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661
Hypericin-Mediated Photodynamic Therapy for Head and Neck Cancers: A Systematic Review
Published 2025-01-01“…Inclusion criteria encompassed preclinical in vitro and in vivo studies and clinical trials focusing on HY-PDT for head and neck malignancies and its subtypes. <b>Results</b>: A total of 13 studies met the inclusion criteria, comprising both in vitro and in vivo investigations. …”
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662
Reprogramming the tumor immune microenvironment using engineered dual-drug loaded Salmonella
Published 2024-08-01“…Here, we report a method of targeted immunotherapy using an attenuated Salmonella typhimurium (SAM-FC) engineered to release dual payloads: cytolysin A (ClyA), a cytolytic anti-cancer agent, and Vibrio vulnificus flagellin B (FlaB), a potent inducer of anti-tumor innate immunity. …”
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663
Factors Associated with Adherence to Diabetic Retinopathy Screening Among Patients Attending a Nurse-Led Community Clinic in Australia: A Qualitative Study
Published 2025-01-01“…The interview data were analyzed thematically using NVivo based on the socio-ecological model, with salience identified by the frequency of the theme. <b>Results:</b> A total of 22 participants completed the interview, including 10 females with a mean age of 60 ± 16.2 years. …”
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664
Post-Diagnostic Aspirin Use in Breast Cancer Treatment: A Systematic Review and Meta-Analysis of Survival Outcomes with Trial Sequential Analysis Validation
Published 2024-12-01“…This meta-analysis evaluates the role of post-diagnostic aspirin use in breast cancer management. <b>Methods</b>: A systematic review and meta-analysis were conducted using PubMed, EMBASE, and Cochrane Library databases. …”
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665
Long-Haul COVID: Investigating the Effects Within the Mauritian Context
Published 2025-01-01“…<b>Research Setting:</b> A cross-sectional study was performed using an adapted online questionnaire, using two definitions of Long COVID, namely the WHO and NICE, SIGN and RCGP definitions. …”
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666
Integrated bioinformatics and experimental analysis of CHAF1B as a novel biomarker and immunotherapy target in LUAD
Published 2025-01-01“…Chromosomal assembly factor 1B (CHAF1B), a p60 component of the CAF-1 complex, is closely linked to tumor incidence and cell proliferation. …”
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667
Xanthomonas citri subsp. citri requires a genus-specific outer membrane protein and TolB to coordinate cell membrane integrity and virulence
Published 2025-02-01“…Pull-down and yeast two-hybrid assays revealed that OMPXan interacts with TolB, a substrate of the Tol/Pal membrane protein system. …”
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668
Controversies in the Application of AI in Radiology—Is There Medico-Legal Support? Aspects from Romanian Practice
Published 2025-01-01“…This narrative review manuscript analyzes the existing literature data regarding the medico-legal aspects of AI application in radiology, highlighting the controversial aspects and the lack of statutory legislative regulations in Romania. <b>Methods</b>: A detailed search was conducted across three electronic databases including MEDLINE/PubMed, Scopus, and Web of Science, with 53 papers serving as the literature corpus of our review. …”
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669
Investigations of Long-Acting Formulations in Children, Adolescents, and Pregnant Women: A Systematic Review
Published 2025-01-01“…After abstract review and duplication removal, full-text articles were obtained for further review, reviewed by two independent reviewers, and disagreements were resolved by a third reviewer. <b>Results:</b> a total of 101 studies of long-acting therapeutics were completed in these populations, and most (80%) of these had a sample size of <100 individuals. …”
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670
Comparison of Visual and Refractive Outcomes Between Refractive Lens Exchange and Keratorefractive Lenticule Extraction Surgery in Moderate to High Myopia
Published 2024-12-01“…<b>Background/Objectives</b>: To evaluate the visual and refractive outcomes of keratorefractive lenticule extraction (KLEx) surgery and refractive lens exchange (RLE) surgery in moderate to high myopia patients. <b>Methods</b>: A retrospective cohort study was performed, and patients receiving KLEx or RLE surgeries with myopia within −3.00 to −10.00 diopter (D) were enrolled. …”
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671
Concept, features and types of corruption
Published 2022-03-01“…The main features of corruption: 1) committed by a special subject of law; 2) is performed within the scope of official authority or related opportunities; 4) is committed for the purpose of obtaining illegal benefit for oneself or other persons; 5) is committed in a certain form (the legislator establishes two forms of corruption: a) acceptance of illegal benefit or acceptance of a promise / proposal of illegal benefit; b) a promise / proposal or provision of illegal benefit to a person specified in Part 1 of Art. 3 of the Law of Ukraine “On Prevention of Corruption”); 6) the result is improper performance of duties. …”
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672
Quantitative Changes in Vascular and Neural Fibers Induced by Subretinal Fluid Excluding the Peripapillary Region in Patients with Chronic Central Serous Chorioretinopathy
Published 2025-01-01“…<b>Background:</b> This study aims to evaluate the quantitative changes in retinal nerve fiber layer (RNFL) thickness and radial peripapillary capillary (RPC) vessel density in patients with chronic central serous chorioretinopathy (CSCR), specifically excluding the peripapillary region. <b>Methods:</b> A prospective case–control study was conducted at the Antalya Training and Research Hospital, Health Sciences University, involving 65 patients with chronic CSCR. …”
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673
Inhibition of A2B Adenosine Receptor Attenuates Intestinal Injury in a Rat Model of Necrotizing Enterocolitis
Published 2020-01-01“…Necrotizing enterocolitis (NEC) is a lethal gastrointestinal tract disease that occurs in premature infants. Adenosine receptor A2B (A2BR) regulates the inflammation cytokine secretion and immune cell infiltration in the colonic pathophysiology conditions. …”
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674
Microbiology and Antimicrobial Resistance Profile in Patients with Diabetic Foot Sepsis at a Central Hospital in Johannesburg, South Africa
Published 2024-12-01“…<b>Materials and Methods</b>: A retrospective review was conducted on patients who were 18-years and older admitted with DFS. …”
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675
Effectiveness of Space Maintainers in Pediatric Patients: A Systematic Review and Meta-Analysis
Published 2025-01-01“…The present study’s goal is to evaluate the survival rate of different types of space maintainers—removable, fixed with a metal base, or fixed with a resin base—indicated for children as a consequence of premature loss of primary teeth. <b>Methods:</b> A systematic review was conducted in accordance with PRISMA recommendations and was previously registered in PROSPERO under registration number: CRD42024534183. …”
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676
Spatial and temporal variability in sea surface temperatures and monsoon dynamics in the northwestern Arabian Sea during the last 43 kyr
Published 2025-01-01“…Comparatively higher SST occurred during some Dansgaard–Oeschger interstadials (D–O 11 and D–O 4–9), the Bølling–Allerød (B–A), and the mid-Holocene. The SST was predominantly influenced by the SW monsoon during warmer periods and the NE monsoon during cold intervals. …”
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677
A Review of Needle Navigation Technologies in Minimally Invasive Cardiovascular Surgeries—Toward a More Effective and Easy-to-Apply Process
Published 2025-01-01“…<b>Background:</b> This review evaluates needle navigation technologies in minimally invasive cardiovascular surgery (MICS), identifying their strengths and limitations and the requirements for an ideal needle navigation system that features optimal guidance and easy adoption in clinical practice. <b>Methods:</b> A systematic search of PubMed, Web of Science, and IEEE databases up until June 2024 identified original studies on needle navigation in MICS. …”
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678
Long-Term Comparative Outcomes of Short Implants Versus Maxillary Sinus Elevation in Posterior Maxilla Rehabilitation
Published 2024-12-01“…This study was designed to assess the clinical outcomes of short implant placement in alveolar ridges with severe bone atrophy, compared with conventional-length implants placed in areas undergoing conventional sinus elevation. <b>Methods</b>: A retrospective split-mouth study was conducted to compare conventional sinus elevation with standard-length implants versus short implants for addressing vertical bone atrophy in the posterior maxilla. …”
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679
Potential Modulatory Role of Phoenixin-14 in Epithelial–Mesenchymal Transition of Endometriotic 12Z Cells
Published 2025-01-01“…This increase coincided with the decrease in <i>THBS2</i> expression, suggesting a potential link between PNX-14, <i>THBS2</i>, and cell viability. <b>Conclusions</b>: A negative correlation between cell viability and the expression of both EMT markers further highlights their possible involvement in the survival and adaptability of ectopic epithelial cells. …”
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680
Rhegmatogenous retinal detachment: current treatment approaches
Published 2020-06-01“…<p> <br> </p> <p> <b>A.V. Doga, D.O. Shkvorchenko, L.A. Kryl’, M.R.…”
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