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1061
Comprehensive analysis of scRNA-seq and bulk RNA-seq reveals the non-cardiomyocytes heterogeneity and novel cell populations in dilated cardiomyopathy
Published 2025-01-01“…Based on gene-specific expression and prior marker genes, we identified 9 distinct subtypes, including fibroblasts, endothelial cells, myeloid cells, pericytes, T/NK cells, smooth muscle cells, neuronal cells, B cells, and cardiomyocytes. Using machine learning methods to quantify bulk RNA-seq data, we found significant differences in fibroblasts, T cells, and macrophages between DCM and normal samples. …”
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1062
Hypoxia specifically induces CADM3 expression in pulmonary endothelial cells and promotes monocyte adhesion
Published 2025-01-01“…The adhesion rate between hypoxia rPEC with CD11b+ cells was the highest, with statistical significance (P<0.01). …”
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1063
Immune status in patients differing in the stage of choroidal melanoma
Published 2024-12-01“…Immunologic evaluation of peripheral blood included absolute counts and percentages of leukocytes, lymphocytes, CD3+ T cells, CD4+ T helpers, CD8+ T suppressors, CD19+ B cells, СD16+ natural killer (NK) cells, phagocytic neutrophil activity (PNA), and imminoglobulins (Ig) A, M and G. …”
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1064
Role of Aging in Ulcerative Colitis Pathogenesis: A Focus on ETS1 as a Promising Biomarker
Published 2025-02-01“…In addition, these hub genes were closely associated with the infiltration of specific immune cells (such as neutrophils, memory B cells, and M2 macrophages) as well as with the JAK/STAT pathway. …”
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1065
Exploring the Kidney-Brain Crosstalk: Biomarkers for Early Detection of Kidney Injury-Related Alzheimer’s Disease
Published 2025-01-01“…These biomarkers are associated with NK_cells_resting and B_cells_memory and could be targeted for intervention in KI-related AD by treating gefitinib and plumbagin.Conclusion: Our study elucidates that ferroptosis may be an important pathway for kidney-brain crosstalk. …”
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1066
Investigating the dual causative pathways linking immune cells and venous thromboembolism via Mendelian randomization analysis
Published 2025-01-01“…Specifically, secreting CD4 regulatory T cells (OR = 0.9084; 95% CI: 0.8418–0.9804; P = 0.0135; FDR = 0.7339) and activated and resting CD4 regulatory T cells (OR = 0.9275; 95% CI: 0.8622–0.9977; P = 0.0433; FDR = 0.8048) suggested a potential protective trend against VTE. On the other hand, B cells expressing CD20 (OR = 1.0697; 95% CI: 1.0227–1.1188; P = 0.0033; FDR = 0.5767) and myeloid cells expressing CD33 (OR = 1.0199; 95% CI: 1.0021–1.0382; P = 0.0296; FDR = 0.7339) may be linked to an increased risk of VTE. …”
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1067
CCR7 and CD48 as Predicted Targets in Acute Rejection Related to M1 Macrophage after Pediatric Kidney Transplantation
Published 2024-01-01“…In the HPA database, CCR7 and CD48 are mainly expressed in T cells, B cells, macrophages, and tissues where these immune cells are distributed. …”
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1068
Identification of a 5-Gene-Based Scoring System by WGCNA and LASSO to Predict Prognosis for Rectal Cancer Patients
Published 2021-01-01“…TCL1A and GPR15 influenced the infiltration levels of B cells and dendritic cells, while the expression of PRPH was positively associated with the abundance of macrophages. …”
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1069
Soluble and cell-based markers of immune checkpoint inhibitor-associated nephritis
Published 2023-01-01“…By peripheral blood flow cytometry analysis, lower absolute CD8+T cells, CD45RA+CD8+ T cells, memory CD27+B cells, and expansion of plasmablasts were prominent features of ICI-nephritis compared with ICI-treated controls. …”
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1070
Synergistic effect of inhibiting CHK2 and DNA replication on cancer cell growth
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1071
The expression of CCL17 and potential prognostic value on tumor immunity in thyroid carcinoma based on bioinformatics analysis
Published 2024-12-01“…Our findings showed that B cells naïve, T cells CD4 memory resting, T cells CD8, T cells regulatory (Tregs), and dendritic cells resting were the main immune components of THCA tumor microenvironment (TME). …”
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