Acute Appendicitis in a Man Undergoing Therapy for Mantle Cell Lymphoma by Michael Linden, Ajay Gopal, Kerstin Edlefsen

“…Although the lymphoid aggregates in the submucosa and lamina propria were rather unremarkable by routine histologic examination, immunohistochemistry revealed the lymphocytes to be predominantly Cyclin D1-overexpressing B cells. To our knowledge, this is the first reported case of acute appendicitis in association with appendiceal involvement by mantle cell lymphoma.…”
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The role of gut microbiota and its metabolites short-chain fatty acids in food allergy by Chen Chen, Chenglong Liu, Ke Zhang, Wentong Xue

“…The multifaceted mechanisms underlying beneficial effects of gut microbiota composition/metabolites on the regulation of diverse cellular pathways in intestinal epithelial cells, dendritic cells, innate lymphoid cells, T cells, B cells and mast cells in the immune system were discussed systematically. …”
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Automatic Generation of Validated Specific Epitope Sets by Sebastian Carrasco Pro, John Sidney, Sinu Paul, Cecilia Lindestam Arlehamn, Daniela Weiskopf, Bjoern Peters, Alessandro Sette

“…In this context, it is desirable to elucidate a method to select validated reference sets of epitopes to allow detection of T and B cells. However, the ever-growing information contained in the Immune Epitope Database (IEDB) and the differences in quality and subjects studied between epitope assays make this task complicated. …”
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The Emerging Functions of Long Noncoding RNA in Immune Cells: Autoimmune Diseases by Keshav Raj Sigdel, Ao Cheng, Yin Wang, Lihua Duan, YanLin Zhang

“…Recent studies have reported that differentiation and activation of immune cells, T cells, B cells, macrophages, and NK cells have correlation with lncRNAs, which have also an essential role in autoimmune diseases such as rheumatoid arthritis and SLE. …”
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Platelet signaling in immune landscape: comprehensive mechanism and clinical therapy by Mengyao Yan, Zhe Wang, Zhiwei Qiu, Yimin Cui, Qian Xiang

“…Platelets participate in both the innate immune system (neutrophils, monocytes/macrophages, dendritic cells (DCs) and Natural Killer (NK) cells and the adaptive immune system (T and B cells). Clinical therapeutic strategies include targeting platelet activation, platelet-immune cell interaction and platelet-endothelial cell interaction, which display positive development prospects. …”
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Propofol Regulates ER Stress to Inhibit Tumour Growth and Sensitize Osteosarcoma to Doxorubicin by Hua Wei, Xinhui Du, Huaping Zhao, Peipei Sun, Jianjun Yang

“…Propofol of increasing concentrations (2.5, 5, 10, and 20 μg/ml) was used to treat the MG63 and 143B cells for 72 hours, and the CCK8 assay was applied to evaluate the tumour cell proliferation. …”
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Modification of Cɛ mRNA Expression by EBV-Encoded Latent Membrane Protein 1 by Kazuhiko Hanashiro, Shigeto Ohta, Masanori Sunagawa, Mariko Nakamura, Mikio Suzuki, Tadayoshi Kosugi

“…Cɛ mRNA expression in IgE-producing cells are modulated by LMP1, which might depend on the differentiation status of B cells upon exposure to allergen.…”
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Follicular T cells and the control of IgE responses by Pablo F. Cañete, Di Yu

“…We will discuss the exclusion of IgE-producing B cells from germinal centers and explore the recently established role of follicular T cell function and heterogeneity in driving or curtailing these immune responses. …”
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Manufacturing Strategy for Multiwalled Carbon Nanotubes as a Biocompatible and Innovative Material by Hisao Haniu, Naoto Saito, Yoshikazu Matsuda, Yuki Usui, Kaoru Aoki, Masayuki Shimizu, Nobuhide Ogihara, Kazuo Hara, Seiji Takanashi, Masanori Okamoto, Koichi Nakamura, Norio Ishigaki, Tamotsu Tsukahara, Hiroyuki Kato

“…We exposed human bronchial epithelial (BEAS-2B) cells to two sizes and six grades of MWCNTs and measured the resulting cell viability, total reactive oxygen and/or nitrogen species (tROS/RNS) production, and cytokine secretion. …”
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Trigger inducible tertiary lymphoid structure formation using covalent organic frameworks for cancer immunotherapy by Liang Zhang, Boxin Zhang, Meng-Jie Zhang, Wenlang Li, Hao Li, Yantian Jiao, Qi-Chao Yang, Shuo Wang, Yuan-Tong Liu, An Song, Hai-Tao Feng, Jianwei Sun, Ryan T. K. Kwok, Jacky W. Y. Lam, Ben Zhong Tang, Zhi-Jun Sun

“…Single-cell sequencing analysis reveals that this is achieved by promotion of cytokine hypersecretion, which facilitates the maturation, proliferation, and migration of T and B cells, critical for triggering TLS formation. Furthermore, the efficacy of COF-mediated phototherapy in inducing TLS formation is validated in both the MC38 and 4MOSC1 female tumor models. …”
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NALCN expression is down-regulated and associated with immune infiltration in gastric cancer by Xuewei Li, Xuewei Li, Na Wu, Chen Wang, Beibei Pei, Xiaoyan Ma, Jun Xie, Jun Xie, Wenhui Yang

“…Immunofluorescence staining confirmed that B cells and CD8 T cells were more abundant in GC tumor tissues with high NALCN expression, whereas Th17 and Th2 cells were less prevalent. …”
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Immunoinformatics Approach for Multiepitope Vaccine Prediction from H, M, F, and N Proteins of Peste des Petits Ruminants Virus by Bothina B. M. Gaafar, Sumaia A. Ali, Khoubieb Ali Abd-elrahman, Yassir A. Almofti

“…Immune Epitope Database (IEDB) analysis resources were used to predict B and T cell epitopes. For B cells, the criteria for electing epitopes depend on the epitope linearity, surface accessibility, and antigenicity. …”
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IFN-γ licenses normal and pathogenic ALPK1/TIFA pathway in human monocytes by Amandine Martin, Solène Caron, Mélissa Marcotte, Pauline Bronnec, Etienne Garneret, Nora Martel, Georgina Maalouf, Pascal Sève, David Saadoun, Yvan Jamilloux, Thomas Henry

“…Notably, IFN-γ is required to license the ALPK1/TIFA pathway in monocytes, while it was dispensable for the responsiveness of B cells. IFN-γ induced TIFA upregulation in monocytes, and TIFA induction was sufficient to recapitulate the licensing effect of IFN-γ. …”
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Host-microbe multiomic profiling identifies distinct COVID-19 immune dysregulation in solid organ transplant recipients by Harry Pickering, Joanna Schaenman, Hoang Van Phan, Cole Maguire, Alexandra Tsitsiklis, Nadine Rouphael, Nelson Iván Agudelo Higuita, Mark A. Atkinson, Scott Brakenridge, Monica Fung, William Messer, IMPACC Network, Ramin Salehi-rad, Matthew C. Altman, Patrice M. Becker, Steven E. Bosinger, Walter Eckalbar, Annmarie Hoch, Naresh Doni Jayavelu, Seunghee Kim-Schulze, Meagan Jenkins, Steven H. Kleinstein, Florian Krammer, Holden T. Maecker, Al Ozonoff, Joann Diray-Arce, Albert Shaw, Lindsey Baden, Ofer Levy, Elaine F. Reed, Charles R. Langelier

“…In addition, transplant recipients exhibit decreased plasmablasts and transitional B cells, and increased senescent T cells. Blood and nasal transcriptional profiling demonstrate unexpected upregulation of innate immune signaling pathways and increased levels of several proinflammatory serum chemokines. …”
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Endoplasmic Reticulum Stress in Systemic Lupus Erythematosus and Lupus Nephritis: Potential Therapeutic Target by Hui-Yuan Li, Li-Feng Huang, Xiao-Rong Huang, Dan Wu, Xiao-Cui Chen, Ji-Xin Tang, Ning An, Hua-Feng Liu, Chen Yang

“…ERS is involved in the dysfunction of B cells, macrophages, T cells, dendritic cells, neutrophils, and other immune cells, causing immune system disorders, such as SLE. …”
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Recent advances in the biosynthesis of polysaccharide-based antimicrobial glycoconjugate vaccines by Yuhui Wang, Yuhui Wang, Yuhui Wang, Yuhui Wang, Haodi Liu, Haodi Liu, Haodi Liu, Haodi Liu, Baoying Wang, Baoying Wang, Baoying Wang, Baoying Wang, Gülzire Gheyret, Jingliang Qin, Hanlin Wang, Hanlin Wang, Hanlin Wang, Hanlin Wang, Yuhan Di, Yuhan Di, Yuhan Di, Yuhan Di, Yanling Wang, Juan Wang, Haining Tan, Haining Tan, Haining Tan, Haining Tan

“…Given that they produce a stronger and longer-lasting immune response than pure polysaccharides that activate only B cells, glycoconjugate vaccines have become one of the most promising vaccine types. …”
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Differences of IL-1β Receptors Expression by Immunocompetent Cells Subsets in Rheumatoid Arthritis by Alina A. Alshevskaya, Julia A. Lopatnikova, Nadezhda S. Shkaruba, Oksana A. Chumasova, Aleksey E. Sizikov, Aleksander V. Karaulov, Vladimir A. Kozlov, Sergey V. Sennikov

“…The resulting data indicate differences in the expression of IL-1β receptors among T cells, B cells, and monocytes in healthy volunteers and in rheumatoid arthritis patients. …”
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miR-155: An Important Role in Inflammation Response by Jingyan Hu, Songli Huang, Xiaoli Liu, Yuan Zhang, Shengli Wei, Xiuhua Hu

“…We analyze the articles about miR-155 for nearly five years, review the advanced study on the function of miR-155 in different inflammatory cells like T cells, B cells, DCs, and macrophages, and then summarize the biological functions of miR-155 in different inflammatory cells. …”
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The Role of Inflammation in the Pathogenesis of Osteoarthritis by Yoke Yue Chow, Kok-Yong Chin

“…This stimulates the release of early-stage inflammatory cytokines like interleukin-1 beta (IL-1β), which in turn induces the activation of signaling pathways, such as nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB), phosphoinositide 3-kinase/protein kinase B (PI3K/AKT), and mitogen-activated protein kinase (MAPK). …”
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Identification of Specific Cell Surface Markers on Immune Cells of Squirrel Monkeys (Saimiri sciureus) by Bharti P. Nehete, Ashley DeLise, Pramod N. Nehete

“…Here, we report specific expression of HLA-DR, PD-1, and CD123 on different circulating immune cell subsets in the peripheral blood that included T cells (CD3+), T cells subsets (CD4+ and CD8+), B cells (CD20+), natural killer (NK) cells (CD3–CD16+), and natural killer T cells (CD3+CD16+) along with different monocyte subsets in squirrel monkey (Saimiri sciureus). …”
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