B-cell multicentric lymphoma in a creole mare - a case report by T.G. Cristo, L. Marian, T.C. Valente, J.J.S. Sá, E.V. Rocha, N.C.C.A. Fernandes, C.S.C. Borges, R.A. Casagrande

“…The association of histopathology and IHC results allowed classifying the neoplastic process as a multicentric large B-cell lymphoma. This type of lymphoma in equines tends to have a silent clinical behavior, with a progressive evolution and clinical condition usually culminating in death.…”
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Diffuse Large B-Cell Lymphoma in an Adolescent Male Presenting as Ureteral Stricture by Christopher D. Jaeger, Kelly L. McAlvany, Shannon N. Zingula, Stephen A. Kramer, Candace F. Granberg

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An Unusual Initial Presentation of Diffuse Large B-Cell Lymphoma as Recurrent Syncope by Kunhwa Kim, Harpreet Kaur, Matthew Chan, Manju Balasubramanian, Sorab Gupta, Vinicius M. Jorge

“…We describe a rare presentation of diffuse large B-cell Lymphoma (DLBCL) with recurrent episodes of syncope. …”
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Myricetin exposure reduces PC differentiation in vitro in primary human B cells by Shabirul Haque, Betty Diamond

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Langerhans Cells, T Cells, and B Cells in Oral Lichen Planus and Oral Leukoplakia by Amal Dafar, Angelica Siarov, Yasaman Mostaghimi, Jairo Robledo-Sierra, Shahin De Lara, Daniel Giglio, Göran Kjeller, Paulo Henrique Braz-Silva, Jenny Öhman, Bengt Hasséus

“…A more robust immune activation involving T cells and B cells is seen in OLP. The role of B cells in OLP needs to be further elucidated. …”
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Prognostic significance of CDK1 expression in diffuse large B-Cell lymphoma by Qiuni Chen, Lei Xu, Chuanyang Lu, Yujie Xue, Xue Gong, Yuye Shi, Chunling Wang, Liang Yu

Subjects: “…Diffuse large B-cell lymphoma…”
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Illuminating the impact of CD38-induced adenosine formation in B-cell lymphoma by Shams ElDoha Galal ElDin Zaiema, Heba Mohamed Saber Hafez, Diaa El-Din Moussa Sherif Abou El-Ela, Rawda Ahmed Alaaeldin Ahmed Mohamed Saad

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Does Adiponectin Act as an Antiangiogenic Factor in B-Cell Chronic Lymphocytic Leukemia? by Stefano Molica, Giovanna Digiesi, Angelo Vacca, Rosanna Mirabelli, Katia Todoerti, Caterina Battaglia, Fortunato Morabito, Antonino Neri, Domenico Ribatti

“…Angiogenesis is involved in the pathogenesis of B-cell chronic lymphocytic leukemia (CLL), and high microvascular density has been found in CLL to be associated with a poor prognosis. …”
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Congenital T-cell activation impairs transitional-to-follicular B-cell maturation in humans by Hugues Allard-Chamard, Kirsty Hillier, Michelle L. Ramseier, Alice Bertocchi, Naoki Kaneko, Katherine Premo, Grace Yuen, Marshall Karpel, Vinay S. Mahajan, Christina Tsekeri, Joseph S. Hong, Jean Vencic, Rory Crotty, Anish V. Sharda, Sara Barmettler, Emma Westermann-Clark, Jolan E. Walter, Musie Ghebremichael, Alex K. Shalek, Jocelyn R. Farmer, Shiv Pillai

“…Abstract: Patients with cytotoxic T-lymphocyte–associated protein 4 (CTLA4) deficiency exhibit profound humoral immune dysfunction, yet the basis for the B-cell defect is not known. We observed a marked reduction in transitional-to-follicular (FO) B-cell development in patients with CTLA4 deficiency, correlating with decreased CTLA4 function in regulatory T cells, increased CD40L levels in effector CD4+ T cells, and increased mammalian target of rapamycin complex 1 (mTORC1) signaling in transitional B cells (TrBs). …”
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Targeting the B-Cell Pathway in Lupus Nephritis: Current Evidence and Future Perspectives by Panagiotis Pateinakis, Athina Pyrpasopoulou

“…Several hypotheses are currently experimentally tested to further elucidate the direct induction of inflammation through interaction of the pathological autoantibodies with intrinsic glomerular components and the triggering of a complement-driven autoinflammatory cascade. B-cells have, in the last decade, emerged as a promising new therapeutic target, as biological treatments successfully attempting B-cell depletion, inhibition of B-cell proliferation and differentiation, or modulation of B-cell function have become bioengineered. …”
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B Cell Activation, Differentiation, and Their Potential Molecular Mechanisms in Osteoarthritic Synovial Tissue by Lu P, Li Y, Yang S, Yao H, Tu B, Ning R

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IL-21 shapes the B cell response in a context-dependent manner by Youngjun Kim, Francesca Manara, Simon Grassmann, Kalina T. Belcheva, Kanelly Reyes, Hyunu Kim, Stephanie Downs-Canner, William T. Yewdell, Joseph C. Sun, Jayanta Chaudhuri

“…Summary: The T-cell-derived cytokine IL-21 is crucial for germinal center (GC) responses, but its precise role in B cell function has remained elusive. Using IL-21 receptor (Il21r) conditional knockout mice and ex vivo culture systems, we demonstrate that IL-21 has dual effects on B cells. …”
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Recurrent Diffuse Large B-Cell Lymphoma with the Initial Manifestation of Retinal Involvement by Wan-Ting Yeh, Jen-Tsun Lin*

Subjects: “…diffuse large b-cell lymphoma…”
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Towards an HCV vaccine: an overview of the immunization strategies for eliciting an effective B-cell response by Gabriel L. Costa, Giuseppe A. Sautto

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B-cell non-Hodgkin's lymphoma in the patient with chronic hepatitis C and mixed cryoglobulinemia by V. S. Adonyeva, Ye. A. Kolodyazhnaya, A. B. Bochkarev

“…Presented case shows development of B-cell non-Hodgkin's lymphoma in the patient with long-term infection of hepatitis C virus and autoimmune disorders, i.e. mixed cryoglobulinemia. …”
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Evaluation of B cell related markers and autoantibodies in rheumatoid arthritis patients treated with abatacept by Ting Wang, Natalia V. Giltiay, Christian Lood, Ning Wang, Bobby Kwanghoon Han

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False Positive B-Cells Crossmatch after Prior Rituximab Exposure of the Kidney Donor by Judith Desoutter, Marie-Joëlle Apithy, Ségolène Bartczak, Nicolas Guillaume

“…We report donor and recipient investigations that revealed unexpected positive B-cells crossmatch, probably due to donor cells, as the donor had received rituximab therapy shortly before organ harvesting, in a context of severe idiopathic thrombocytopenic purpura. …”
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T Cell/Histiocyte-Rich Large B Cell Lymphoma of the Thymus: A Diagnostic Pitfall by Jie Xu, Xiaojun Wu, Vishnu Reddy

“…T cell/histiocyte-rich large B cell lymphoma (THRLBCL) is predominantly a nodal disease, with extranodal involvement, such as bone marrow, spleen, and liver. …”
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A prognostic model of 8-T/B cell receptor-related signatures for hepatocellular carcinoma by Xuan Zuo, Hui Li, Shi Xie, Mengfen Shi, Yujuan Guan, Huiyuan Liu, Rong Yan, Anqi Zheng, Xueying Li, Jiabang Liu, Yifan Gan, Haiyan Shi, Keng Chen, Shijie Jia, Guanmei Chen, Min Liao, Zhanhui Wang, Yanyan Han, Baolin Liao

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Clonally Related Plasmablastic Lymphoma Simultaneously Occurring with Diffuse Large B-Cell Lymphoma by Norisato Hashimoto, Tomoki Ueda, Shinichiro Hiraiwa, Takuma Tajiri, Naoya Nakamura, Kenji Yokoyama

“…PBL immunohistochemically expresses plasmacytic markers and lacks pan B-cell markers. The cells of origin of PBL are considered to be plasmablasts. …”
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