Posttransplant Lymphoproliferative Disease Presenting as an Extracranial Mass by Reuben J. Arasaratnam, Alejandro Restrepo

“…We report a renal transplant recipient presenting with an extracranial frontoparietal soft tissue mass that was subsequently diagnosed as a B-cell lymphoma. The patient was treated successfully with immunosuppression reduction, anti-CD20 monoclonal antibody therapy, and cytotoxic chemotherapy. …”
Get full text

Th2 cells and cytokine networks in allergic inflammation of the lung by Anthony J. Coyle, Shogo Tsuyuki

“…IL-4 has emerged as a central target, not only for B cell IgE production, but also in the commitment of both CD4+ and CD8+ T cells to cells with Th2 effector function capable of secreting IL-5 resultlng in eosinophilic inflammation. …”
Get full text

EBV-RELATED LYMPHOPROLIFERATIVE DISEASES: A REVIEW IN LIGHT OF NEW CLASSIFICATIONS by Pietro Tralongo, Arianna Bakacs, Luigi Maria Larocca

“…However, in some populations, EBV has been linked to a variety of B-cell lymphoproliferative disorders (LPDs), such as Burkitt lymphoma, classic Hodgkin lymphoma, and other LPDs. …”
Get full text

Control of Herpesvirus Infection in Organ Transplant Recipients by Nina E Tolkoff-Rubin, Robert H Rubin

“…This in turn is translated into clinical disease: fever; pneumonia; gastrointestinal ulcerations; broad-based suppression of host defences leading to opportunistic superinfection and, perhaps, allograft injury in the case of CMV; and B cell lymphoproliferative disease in the case of EBV. …”
Get full text

Anaplastic, T-Cell, Non-Hodgkin's Lymphoma Presenting with Haematuria by C. Blick, S. Abdelhadi, D. Bailey, A. Muneer

“…Although accounting for only 0.2% of all primary bladder tumours, the majority of bladder lymphomas are B-cell lymphomas. T-cell lymphoma of the bladder is incredibly rare. …”
Get full text

Mechanism of triptolide regulating proliferation and apoptosis of hepatoma cells by inhibiting JAK/STAT pathway by Wang Guanglian, Zhu Zhenxin, Sun Zhengang, Yang Zhiqi

“…The apoptosis rate of 10 ng/mL transforming growth factor-beta + high-dose group was reduced than that in the high-dose group, and the expression of p-JAK1 and p-STAT3 protein was higher than that in the high-dose group (P < 0.05). The activity of B-cell lymphoma/leukemia-2-associated X protein (Bax) protein and cysteine aspartic acid protease (Caspase)-3/9 in TPL cells at each dose was raised than that in the control group, and the expression of B-cell lymphoma/leukemia-2 (Bcl-2) protein was decreased than that in the control group. …”
Get full text

A bioinformatics approach for identifying the probable cause of the cross-interaction of antibodies to the antigenic protein HPV16 L1 with the HPV6 L1 protein by A. S. Stolbikov, R. K. Salyaev, N. I. Rekoslavskaya

“…For the analysis of antigenic determinants, the programs BepiPred-2.0: Sequential B-Cell Epitope Predictor, DiscoTope 2.0 Server and SYFPEITHI have been used. …”
Get full text

Serological Immunoglobulin-Free Light Chain Profile in Myasthenia Gravis Patients by Umberto Basile, Mariapaola Marino, Cecilia Napodano, Krizia Pocino, Paolo Emilio Alboini, Francesca Gulli, Amelia Evoli, Carlo Provenzano, Emanuela Bartoccioni

“…From our data, FLCs appear to be a sensitive marker of B cell activation in MG. Further investigations are necessary to exploit their potential as reliable biomarkers of disease activity.…”
Get full text

Flow cytometric characterisation of acute leukaemia in adolescent and adult Ethiopians by Jemal Alemu, Balako Gumi, Aster Tsegaye, Abdulaziz Sherif, Fisihatsion Tadesse, Amha Gebremedhin, Rawleigh Howe

“…A subset of acute leukaemia, CD19+/CD56+ AML was identified in 3 cases (6% of AML). Of the B-cell ALL cases, 21 (42%) were CD34+/CD10+/CD66c+, 10% were CD34+/CD10+/CD66c–, 32% were CD34-/CD10+, and 6% were CD34+/CD10–. …”
Get full text

Cellular therapies in rheumatic and musculoskeletal diseases by Pedro Franco-Fuquen, Juana Figueroa-Aguirre, David A. Martínez, Eider F. Moreno-Cortes, Juan E. Garcia-Robledo, Fabio Vargas-Cely, Daniela A. Castro-Martínez, Mustafa Almaini, Januario E. Castro

“…This strategy has demonstrated efficacy in treating B-cell malignancies by achieving long-term depletion of malignant and normal B cells. …”
Get full text

Delta-Like-1 Changes the Immunomodulatory Property of OP9 Cells by Lei Zhang, Rui-Jie Dang, Yan-Mei Yang, Dian-Chao Cui, Ping Li, Yan-Li Ni, Tong Hao, Changyong Wang, Xiao-Xia Jiang, Nan-Zhu Fang

“…DL1 overexpression alone changed the properties of OP9 cells in addition to their role in early B cell development.…”
Get full text

A Case of Rituximab-Induced Necrotizing Fasciitis and a Review of the Literature by Abdullateef Abdulkareem, Ryan S. D’Souza, Oluwaseun Shogbesan, Anthony Donato

“…Rituximab is a generally well-tolerated immunosuppresive medication used for B-cell malignancies and some rheumatological disorders. …”
Get full text

Inflammatory Duodenal Polyposis Associated with Primary Immunodeficiency Disease: A Novel Case Report by Irfan Ali Shera, Sheikh Mudassir Khurshid, Mohd Shafi Bhat

“…Agammaglobulinemia is a rare form of B-cell primary immunodeficiency disease characterized by reduced levels of IgG, IgA, or IgM and recurrent bacterial infections. …”
Get full text

Plasmablastic lymphoma of the sphenoid bone in an immunocompetent patient: A diagnostic challenge by Anurag Singh, Vinita Agrawal, Alka Singh

“…Plasmablastic lymphoma is a rare type of highly aggressive B-cell non-Hodgkin lymphoma that usually occurs in immunocompromised patients and involves chiefly extra-nodal sites such as the oral cavity, jaw, gastrointestinal tract, soft tissue, bone, and skin. …”
Get full text

Second Cancers in a Patient with Gastric MALT Lymphoma by Lucy Navsaria, Alfonso Badillo, Michael Wang

“…Mucosa-associated lymphoid tissue (MALT) lymphoma is an extranodal low-grade B-cell lymphoma, which is thought to arise from a background of chronic immune stimulation, bacterial, viral, or autoimmune stimuli. …”
Get full text

Successful Treatment of Disseminated Subcutaneous Panniculitis-Like T-Cell Lymphoma with Single Agent Oral Cyclosporine as a First Line Therapy by Nida Iqbal, Vinod Raina

“…Currently there are no standardized therapies for SPTL; however good responses have been seen with chemotherapy regimens generally employed for B-cell lymphomas. Cyclosporine, an immunosuppressant, has shown good responses in relapsed/refractory SPTL; however its use in first line setting is not well established. …”
Get full text

Delftia Acidovorans: A Rare Pathogen in Immunocompetent and Immunocompromised Patients by Huseyin Bilgin, Abdurrahman Sarmis, Elif Tigen, Guner Soyletir, Lutfiye Mulazimoglu

“…The present article describes a B cell lymphoblastic leukemia patient with D acidovorans pneumonia who was successfully treated with antibiotic therapy. …”
Get full text

Cerebral Amyloidoma Resulting from Central Nervous System Lymphoplasmacytic Lymphoma: A Case Report and Literature Review by Geetha Jagannathan, Guldeep Uppal, Kevin Judy, Mark T. Curtis

“…Cerebral amyloid accumulation can be the result of a number of disease states and it is crucial for proper patient care to identify the pathogenic process leading to amyloidoma formation. Low grade clonal B-cell processes are one cause of cerebral amyloidomas. …”
Get full text

Cytomegalovirus Retinitis in Primary Immune Deficiency Disease by Jia Jeane Ngai, Ka Lung Chong, Shelina Oli Mohamed

“…Case Report. 13-year-old child with combined T and B cell deficiencies was diagnosed of bilateral zone 1 CMV retinitis. …”
Get full text

Life-threatening Pneumocystis jiroveci Pneumonia with Cytomegalovirus Coinfection in a Follicular Lymphoma Patient During Rituximab-based Chemotherapy by Mu-Chun Yang, Sheng-Kang Chiu, Jong-Kai Hsiao, Woei-Yau Kao

“…In the era of target therapy, we face the challenge of the risk of opportunistic infection in patients with B-cell lymphoma who receiving rituximab-based chemotherapy. …”
Get full text