CASE PRESENTATION by Goga Iolanda, Cioc Enache, Boghici Elena-Monica, Moraru Mihaela, Nichita Monica-Adriana, Dumitrescu Elena, Pirlea Andrei-Daniel, Zob Daniela-Luminiţa

“…Diffuse large B-cell lymphoma and metachronous metastatic renal cancer – a case report Malignant melanoma of the leg – challenges. …”
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Towards a Vaccine Against Rheumatic Fever by L. Guilherme, K. C. Faé, F. Higa, L. Chaves, S. E. Oshiro, S. Freschi de Barros, C. Puschel, M. A. Juliano, A. C. Tanaka, G. Spina, J. Kalil

“…We identified T and B cell epitopes with 22 and 25 amino acid residues, respectively. …”
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Immunoinformatics Approach for Epitope-Based Peptide Vaccine Design and Active Site Prediction against Polyprotein of Emerging Oropouche Virus by Utpal Kumar Adhikari, Mourad Tayebi, M. Mizanur Rahman

“…The predicted eight conformational B-cell epitopes represent the accessibility for the entered virus. …”
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CAR T cells for treating autoimmune diseases by Dimitrios Mougiakakos, Ulrike Koehl, Stephan Fricke, Ulrich Blache, Sandy Tretbar

“…We will cover first clinical results of applying anti-CD19 and anti-B cell maturation antigen CAR T cells for B cell elimination in systemic lupus erythematosus, refractory antisynthetase syndrome and myasthenia gravis, respectively. …”
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Maltoma of Thyroid: A Rare Thyroid Tumour by Navisha Latheef, Vijendra Shenoy, M. Panduranga Kamath, Mahesh Chandra Hegde, A. Raghavendra Rao

“…Marginal zone lymphoma encompasses a heterogeneous group of B-cell tumours that variously arise within the lymph nodes, spleen, or extranodal tissues. …”
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The effect of lemon extract (Citrus limon) on the blood sugar levels and pancreatic beta cell regeneration in alloxan-induced hyperglycemic mice by Petrus Mantur, Efrisca Meliyuita Br. Damanik, Elisabeth Levina Sari Setianingrum, Prisca Pakan

“…Objectives: This study explored the effect of lemon (Citrus limon) extract on blood sugar levels and pancreatic b cell regeneration in alloxan-induced hyperglycemic mice (Mus musculus). …”
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Follicular Regulatory T Cells in Systemic Lupus Erythematosus by Xin Xia, Jun Yang, Shengjun Wang

“…They can disrupt Tfh cell- and B cell-linked recognition, induce Tfh apoptosis, and suppress B cell function. …”
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Primary Pulmonary Anaplastic Large Cell Lymphoma: A Rare Malignancy and Rare Cause of the Luftsichel Sign by Elizabeth Von Ende, Travis Kauffman, Philip A. Munoz, Santiago Martinez-Jiménez

“…Of these, the large majority are made up of marginal zone B-cell lymphoma and diffuse large B-cell lymphoma. …”
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Runaway Train: A Leaky Radiosensitive SCID with Skin Lesions and Multiple Lymphomas by Børre Fevang, Unn Merete Fagerli, Hanne Sorte, Harald Aarset, Håkon Hov, Marit Langmyr, Thomas Morten Keil, Ellen Bjørge, Pål Aukrust, Asbjørg Stray-Pedersen, Tobias Gedde-Dahl

“…The nuclease Artemis is essential for the development of T-cell and B-cell receptors and repair of DNA double-strand breaks, and a loss of expression or function will lead to a radiosensitive severe combined immunodeficiency with no functional T-cells or B-cells (T-B-SCID). …”
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Scoping review of the applications of peptide microarrays on the fight against human infections. by Arthur Vengesai, Maritha Kasambala, Hamlet Mutandadzi, Tariro L Mduluza-Jokonya, Takafira Mduluza, Thajasvarie Naicker

“…The research domains explored included the use of peptide microarrays in the mapping of linear B-cell and T cell epitopes, antimicrobial peptide discovery, immunosignature characterisation and disease immunodiagnostics. …”
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Immunoinformatics design of a novel multiepitope vaccine candidate against non-typhoidal salmonellosis caused by Salmonella Kentucky using outer membrane proteins A, C, and F. by Elayoni E Igomu, Paul H Mamman, Jibril Adamu, Maryam Muhammad, Abubarkar O Woziri, Manasa Y Sugun, John A Benshak, Kingsley C Anyika, Rhoda Sam-Gyang, David O Ehizibolo

“…Furthermore, we identified seven highly immunogenic linear B-cell epitopes and three conformational B-cell epitopes. …”
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Inhibition of Germinal Centre Apoptotic Programmes by Epstein-Barr Virus by Lindsay C. Spender, Gareth J. Inman

“…To establish a persistent latent infection, Epstein-Barr virus (EBV) faces a challenge in that the virus-infected host cell must transit through the germinal centre reaction. This is a site of B cell differentiation where antibody responses are optimised, and the selection criteria for B cells are stringent. …”
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Mixed-phenotype Acute Leukemia with Trilineage Differentiation in a 3-year-old Child by I Gusti Ayu Mardewi, Anak Agung Wiradewi Lestari, I Nyoman Wande, Ni Nyoman Mahartini

“…Leukemia phenotyping identified a mixed lineage involving myeloid, B-cell, and T-cell markers, supporting the diagnosis of MPAL. …”
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Mechanisms behind Functional Avidity Maturation in T Cells by Marina Rode von Essen, Martin Kongsbak, Carsten Geisler

“…During an immune response antigen-primed B-cells increase their antigen responsiveness by affinity maturation mediated by somatic hypermutation of the genes encoding the antigen-specific B-cell receptor (BCR) and by selection of higher-affinity B cell clones. …”
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Primary Intraocular Lymphoma in a Patient with Bilateral Epstein-Barr Virus Panuveitis by Seyedeh Maryam Hosseini, Mojtaba Abrishami, Elham Barashki, Ghodsieh Zamani

“…There may be an association between EBV panuveitis and primary intraocular B-cell lymphoma.…”
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The Ratio of CD226 and TIGIT Expression in Tfh and PD-1+ICOS+Tfh Cells Are Potential Biomarkers for Chronic Antibody-Mediated Rejection in Kidney Transplantation by Ji-wen Fan, Yu Fan, Zheng-li Wan, Lin Yan, Ya-mei Li, Yang-juan Bai, Lan-lan Wang, Jie Chen, Yi Li

“…Chronic antibody-mediated rejection (CAMR) is the main cause of graft failure. Tfh and B cells are key immune cells that play important roles in CAMR. …”
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Modeling the co-infection of HTLV-2 and HIV-1 in vivo by A. M. Elaiw, E. A. Almohaimeed, A. D. Hobiny

“…The results suggested that the B-cell response regulates and inhibits the spread of HIV-1. …”
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Targeting B and T Lymphocyte Attenuator Regulates Lupus Disease Development in NZB/W Mice by Gherardi L, Aubergeon L, Sayah M, Fauny JD, Dumortier H, Monneaux F

“…This beneficial effect was associated with a decrease in circulating B cell and spleen follicular B cell numbers. Regarding its mode of action, we demonstrated that the 6F7 antibody is not a depleting antibody and does not block HVEM binding to BTLA, but instead induces BTLA down modulation and exhibits in vivo agonist activity.Conclusion: Overall, our data confirm the involvement of BTLA in lupus pathogenesis and provide the first evidence that BTLA is a potential therapeutic target for the treatment of lupus.Keywords: systemic lupus erythematosus, BTLA, lupus mice, inhibitory receptors…”
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Immunoregulatory programs in anti‐N‐methyl‐D‐aspartate receptor encephalitis identified by single‐cell multi‐omics analysis by Xinhui Li, Yicong Xu, Weixing Zhang, Zihao Chen, Dongjie Peng, Wenxu Ren, Zhongjie Tang, Huilu Li, Jin Xu, Yaqing Shu

“…In parallel, single‐cell B cell receptor sequencing (scBCR‐seq) and repertoire analysis were conducted to assess antigen‐driven clonal expansion within the B cell population. …”
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The trend of phylogenetic and epitope variations of SARS-CoV-2 Omicron sub-lineages in Iran by Mehdi Shabani, Ahmad Nejati, Jila Yavarian, Jila Yavarian, Kaveh Sadeghi, Sevrin Zadheidar, Akram Sadat Ahmadi, Monire Ghadirali, Arghavan Zebardast, Adel Abedi, Mohammad Hossein Najmi, Nazanin-Zahra Shafiei-Jandaghi, Talat Mokhtari-Azad

“…The low B cell epitopes conservation rate among Omicron sub-lineages underscored the escaping from neutralizing humoral immunity. …”
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