Silent witnesses: unveiling the epidemic of femicides in North-west Tshwane, South Africa – a decade of analysis by Yaseen Bismilla, K. K. Hlaise, C. Van Wyk

“…The inclusion criteria comprised female cases at autopsy, with a suspected homicidal manner of death. …”
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Temperature and repeated catecholamine surges modulate regional wall motion abnormalities in a rodent takotsubo syndrome model by Ermir Zulfaj, AmirAli Nejat, Abdulhussain Haamid, Aaron Espinosa, Ahmed Elmahdy, Tetiana Pylova, Sandeep Jha, Björn Redfors, Elmir Omerovic

“…Complications were evaluated through ECG, autopsy, and blood gas analysis. The TS phenotype showed reduced longitudinal strain with RWMA characterized by apical end-systolic akinesia/dyskinesia, a contracting base, and a narrow transition zone, resulting in apical ballooning. …”
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Extended Renal Artery Denervation Is Associated with Artery Wall Lesions and Acute Systemic and Pulmonary Hemodynamic Changes: A Sham-Controlled Experimental Study by Aleksandr D. Vakhrushev, Heber Ivan Condori Leandro, Natalia S. Goncharova, Lev E. Korobchenko, Lubov B. Mitrofanova, Dmitry S. Lebedev, Evgeny N. Mikhaylov

“…In the RDN group, radiofrequency ablation was performed in all available arteries and their segments. An autopsy study of the renal arteries was carried out in both groups. …”
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The influence of external factors on the development of olfactory disorders in patients with the coronavirus disease 2019: an immunomorphological assessment by I.S. Shponka, O.M. Usova

“…The purpose of the study is to clarify the immunomorphological features of the olfactory epithelium of the nasal cavity of patients with the 2019 coronavirus disease, taking into account the background pathological changes in the structures of this area for a better understanding of the mechanisms of the development of olfactory dysfunction during infection with the SARS-CoV-2 coronavirus, depending on the presence of aggravating factors. Autopsy material was used for the study, namely fragments of the mucous membrane of the upper parts of the nasal cavity (olfactory epithelium), obtained from 20 deceased (8 women and 12 men) aged 53 to 86 years with a diagnosis of "Coronavirus disease 2019", confirmed by laboratory (polymerase chain reaction) and olfactory disorders of various degrees in the anamnesis. …”
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Influence of Gender on Cardiac and Encephalic Inflammation in the Elderly with Cysticercosis: A Case Control Study by Camila Lourencini Cavellani, Rosana Rosa Miranda Corrêa, Mara Lúcia Fonseca Ferraz, Laura Penna Rocha, Ana Carolina Guimarães Faleiros, Ruy de Souza Lino Junior, Marlene Antônia dos Reis, Vicente de Paula Antunes Teixeira

“…We aimed to quantify the inflammatory infiltrate caused by cysticercosis, which is related to aging, in the heart and in the encephalon. Methods. 75 autopsy protocols with cysticercosis diagnosis from department of pathology at a university hospital from 1970 to 2008 were reviewed. …”
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Tuberculosis and HIV/AIDS-attributed mortalities and associated sociodemographic factors in Papua New Guinea: evidence from the comprehensive health and epidemiological surveillanc... by Chalapati Rao, Willie Pomat, Tony Okely, Bang Nguyen Pham, Norah Abori, Vinson D Silas, Ronny Jorry

“…This study examines TB and HIV/AIDS mortalities and associated sociodemographic factors in PNG.Method As part of a longitudinal study, verbal autopsy (VA) interviews were conducted using the WHO 2016 VA Instrument to collect data of 926 deaths occurred in the communities within the catchment areas of the Comprehensive Health and Epidemiological Surveillance System from 2018 to 2020.InterVA-5 cause of deaths analytical tool was used to assign specific causes of death (COD). …”
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Lethal necrotizing granulomatous vasculitis after bariatric surgery and bilateral mammaplasty by O. V. Blagova, D. Kh. Aynetdinova, A. V. Nedostup, N. A. Novikova, Ye. A. Kogan, Yu. V. Lerner, L. V. Kozlovskaya, V. V. Rameyev, N. A. Mukhin

“…Despite provided corticosteroid and cyclophosphan treatment, the disease progressed (focal affection of the lungs) and the patient died of brain stem hemorrhage. Autopsy revealed the signs of vasculitis with involvement of the brain, skin, mediastinal lymphnodes, lungs, as well as the signs of chronic inflammation, atrophy of breast gland lobules, embolization of the focal lymphatics by the implant substance, ulceronecrotic enteritis of defunctioning bowel, severe liver steatosis with the chronic vitamin deficiency. …”
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Clarithromycin-Associated Acute Liver Failure Leading to Fatal, Massive Upper Gastrointestinal Hemorrhage from Profound Coagulopathy: Case Report and Systematic Literature Review by Ahmed I. Edhi, Seifeldin Hakim, Christienne Shams, Damanpreet Bedi, Mitual Amin, Mitchell S. Cappell

“…Esophagogastroduodenoscopy was planned after massive blood product transfusions, but the patient rapidly expired from hemorrhagic shock. Autopsy revealed a golden-brown heavy liver with massive hepatic necrosis and sinusoidal congestion. …”
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Primary Terminal Haemochromatosis in a 50 Year-Old Patient by M. I. Gonik, M. S. Zharkova, O. Yu. Kiseleva, E. V. Berezina, Sh. A. Ondos, Yu. V. Lerner, E. A. Kogan, V. T. Ivashkin

“…Despite a cardiovascular and renal failure compensation therapy and albumin transfusion, the patient died. Autopsy revealed a marked organ infiltration with haemosiderin (heart, stomach, liver, pancreas, lungs, kidneys, adrenal glands).Conclusion. …”
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Early Pathologic Findings of Bronchiolitis Obliterans after Allogeneic Hematopoietic Stem Cell Transplantation: A Proposal from a Case by Rie Nakamoto-Matsubara, Hidekazu Nishikii, Kenji Yamada, Masafumi Ito, Yuichi Hasegawa, Naoki Kurita, Naoshi Obara, Yasushi Okoshi, Kazumi Suzukawa, Yasuhisa Yokoyama, Mamiko Sakata-Yanagimoto, Masayuki Noguchi, Shigeru Chiba

“…Definitive BO followed, which was proven by both clinical course and autopsy. While alloreactive lymphocytes associated with chronic graft-versus-host disease are believed to initiate BO, we present a rare case that directly implies such a scenario.…”
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Concurrent severe fever with thrombocytopenia syndrome virus outbreaks on multiple fox farms, China, 2023 by Jian Sun, Lei Qian, Delong Li, Xiurong Wang, Hong Zhou, Cixiu Li, Edward C. Holmes, Jianke Wang, Juan Li, Weifeng Shi

“…These animals exhibited loss of appetite and weight loss, finally resulting in death. In autopsy and histopathology, prominently enlarged spleens and extensive multi-organ hemorrhage were observed, respectively, indicating severe systemic effects. …”
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Development of delayed pulmonary toxicities and transcriptional changes in pre-existing interstitial lung disease mice after partial thoracic irradiation by Jiamei Fu, Xinglong Liu, Yuchuan Zhou, Shengnan Zhao, Liang Zeng, Yan Pan, Jianghong Zhang, Kevin M. Prise, Chunlin Shao, Yaping Xu

“…Enhanced lung injury was observed in the sRRLI model, including higher mortality and pulmonary function loss within six months compared to the mono-treatment groups. Autopsy revealed that bilateral diffuse alveolar damage (DAD) with an overlap of exudative, proliferative, and fibrosing patterns was usually presented in the sRRLI model. …”
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Plasma phospho-tau217 as a predictive biomarker for Alzheimer’s disease in a large south American cohort by Neetesh Pandey, Zikun Yang, Basilio Cieza, Dolly Reyes-Dumeyer, Min Suk Kang, Rosa Montesinos, Marcio Soto-Añari, Nilton Custodio, Lawrence S. Honig, Giuseppe Tosto

“…Most investigations have previously focused on highly selected cohorts with established AD-endophenotypes (CSF biomarkers, autopsy report, PET etc.), while data on cohorts with clinical assessment are currently lacking, especially in non-European populations.…”
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Adrenal aldosterone synthase (CYP11B2) histopathology and its association with disease-induced sudden death: a cross-sectional studyResearch in context by Antero Ylänen, Juhani Isojärvi, Antti Virtanen, Helena Leijon, Tiina Vesterinen, Aapo L. Aro, Heini Huhtala, Eeva Kokko, Ilkka Pörsti, Marianna Viukari, Pasi I. Nevalainen, Niina Matikainen

“…Methods: In this study, autopsies and histopathological analyses, including aldosterone synthase staining of adrenal glands, were performed on 403 consecutive individuals who experienced sudden death. …”
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A Case of Medullary Carcinoma of the Jejunum Combined with the Intestinal Lymphangiectasia Accompanied by the Malabsorption Syndrome by O. A. Lobanova, D. S. Trusova, M. A. Afonina, V. E. Varentsoy, D. D. Protsenko, N. V. Kretova, N. B. Serezhnikova, M. A. Peshkova, N. V. Zharkov, S. E. Kochetkova, Yu. Yu. Stepanova, Z. D. Shtanev, K. A. Vekhova, V. A. Yumasheva, A. O. Kolesnikova, M. Akan, M. O. Chanturiya, T. V. Serebrov, A. S. Tertychnyy, H. Guski, E. E. Rudenko, T. A. Demura, E. A. Kogan

“…Aim: to present a clinical and morphological observation of an extremely rare combination of medullary carcinoma of the jejunum and intestinal lymphangiectasia in a 33-year-old patient with clinical features of malabsorption syndrome over the 10 years.Key points. An autopsy revealed a tumor formation spreading from the wall of the jejunum to the mesentery, with metastases to the mesenteric lymph nodes. …”
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Increased plasma DOPA decarboxylase levels in Lewy body disorders are driven by dopaminergic treatment by Katharina Bolsewig, Eline A. J. Willemse, Pascual Sánchez-Juan, Alberto Rábano, Minerva Martínez, James D. Doecke, Giovanni Bellomo, Lisa Vermunt, Daniel Alcolea, Steffen Halbgebauer, Sjors in ‘t Veld, Niklas Mattsson-Carlgren, Katerina Veverova, Christopher J. Fowler, Lynn Boonkamp, Marleen Koel-Simmelink, Zulaiga Hussainali, Daimy N. Ruiters, Lorenzo Gaetani, Andrea Toja, Juan Fortea, Yolande Pijnenburg, Afina W. Lemstra, Wiesje M. van der Flier, Jakub Hort, Markus Otto, Oskar Hansson, Lucilla Parnetti, Colin L. Masters, Alberto Lleó, Charlotte E. Teunissen, Marta Del Campo Milán

“…Here we evaluate plasma DDC, measured by proximity extension assay, and the effect of dopaminergic treatment in three independent LBD (with a focus on dementia with Lewy bodies (DLB) and Parkinson’s disease (PD)) cohorts: an autopsy-confirmed cohort (n = 71), a large multicenter, cross-dementia cohort (n = 1498) and a longitudinal cohort with detailed treatment information (n = 66, median follow-up time[IQR] = 4[4, 4] years). …”
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Splenic artery aneurysms – a systematic review of the literature by Marta Machado, Andreia Coelho, João Peixoto, Luís Fernandes, Roberto Boal, Francisco Basílio, Patrícia Carvalho, Beatriz Guimarães, Pedro Brandão, Alexandra Canedo

“… INTRODUCTION: Splenic artery aneurysms (SAA) are the most frequent (50 to 75%) abdominal visceral arterial aneurysms. In autopsy studies, the overall incidence is 0.01%, increasing to 10.4% with age. …”
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Superdominant Right Coronary Artery with Absence of Left Circumflex and Anomalous Origin of the Left Anterior Descending Coronary from the Right Sinus: An Unheard Coronary Anomaly... by Marcos Danillo Peixoto Oliveira, Fernando Roberto de Fazzio, José Mariani Junior, Carlos M. Campos, Luiz Junya Kajita, Expedito E. Ribeiro, Pedro Alves Lemos

“…Most of them are discovered as incidental findings during coronary angiographic studies or at autopsies. We present herein the case of a 70-year-old man with symptomatic severe aortic valvar stenosis whose preoperative coronary angiogram revealed a so far unreported coronary anomaly circulation pattern.…”
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Neurofibromatosis Type I and Stromal Tumor with a Multiple Digestive Localization by Amina Chaka, Farouk Ennaceur, Mohamed Amine Tormen, Ibtissem Korbi, Faouzi Noomen, Khadija Zouari

“…The incidence of gastroduodenal stromal tumor during Recklinghausen disease can reach 35% in autopsies and 5% in clinical cases. In our case, the diagnosis of neurofibromatosis type I was made in a middle-aged women initially diagnosed with a pancreaticoduodenal tumor.…”
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Pathomorphological Study of Coronary Atherosclerosis in Deceased Patients by Halina Pérez Álvarez, José Fernández-Brito Rodríguez

“…The universe consisted of 183 autopsies, consecutively from the Institute of Legal Medicine, from 2018 to 2019 and the population of 108 deceased divided by age groups. …”
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