Isolated anti-SS-B (La) antibodies: rare occurrence and lack of diagnostic value by Xavier Mariette, Gaetane Nocturne, Pascale Chretien, Claire Goulvestre, Paul Cioni, Eric Ballot, Dounia Khelifi-Touhami

“…Immunodot was performed in 186 of them and confirmed anti-SS-B positivity in 61 patients (3.6% of anti-SS-B positivity). 24 patients (39.3%) presented with a history of various autoimmune or autoinflammatory diseases and only 6 were diagnosed with a new connective tissue disease. …”
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TEVAR for acute type B aortic dissection in pregnant women (35 weeks gestation) with Takayasu's arteritis after cesarean section: a rare case report and literature review by Taiyu Bi, Xiaotian Duan, Yipeng Yin

“…BackgroundTakayasu's arteritis (TA) is an autoimmune disease that invades large arteries and mostly occurs in women of childbearing age. …”
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Low-Dose Irradiation Differentially Impacts Macrophage Phenotype in Dependence of Fibroblast-Like Synoviocytes and Radiation Dose by Lisa Deloch, Jana Fuchs, Michael Rückert, Rainer Fietkau, Benjamin Frey, Udo S. Gaipl

“…Rheumatoid arthritis (RA) is a multifactorial autoimmune disease whose main hallmark is inflammation and destruction of the joints. …”
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Association between spasticity and neuropathic pain in patients with multiple sclerosis by B. Afanasjeva, R. Balnytė

“…Multiple sclerosis (MS) is a chronic inflammatory autoimmune demyelinating central nervous system disease. …”
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COVID-19 Recombinant mRNA Vaccines and Serious Ocular Inflammatory Side Effects: Real or Coincidence? by Arash Maleki, Sydney Look-Why, Ambika Manhapra, C. Stephen Foster

“…Conclusion: There may be a correlation between ocular inflammatory diseases with autoimmune mechanism and the mRNA COVID-19 vaccination.…”
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Population characteristics, prescription patterns and glycemic control of users of flash glucose monitoring systems in Brazil: a real-world evidence study by Karla Santo, Josué Nieri, Karine Risério, Karla F. S. Melo

“…Methods This study is a cross-sectional retrospective study using anonymized aggregated data manually inputted by Glic™ users who self-reported a diagnosis of type 1 diabetes (T1DM), type 2 diabetes (T2DM), gestational diabetes (GDM) and latent autoimmune diabetes in adults (LADA). Results Of the 12,727 individuals included in this study, 11,007 (86.5%) reported their glucose monitoring method to be BGM, while 1720 (13.5%) reported using fCGM. …”
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Changes in Serum Immunoglobulin Levels Play as Predictors of Treatment Response and Prognosis in Pediatric Idiopathic Nephrotic Syndrome During the Remission Phase by Amin sadat Sharif, Naghmeh Nickravesh, Marzieh Heidarzadeh Arani, Mohammad Javad Azadchehr, Hossein Motedayyen

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Immune modulation effects of curcumin in pristane-induced lupus mice by Handono Kalim, Kusworini Handono, Takhta Khalasha, Mirza Zaka Pratama, Tri Wahyudi Iman Dantara, Ayu Pramitha Wulandari, Fahimma Albinsaid, Sofi Nur Fitria, Muhammad Vardian Mahardika

“…Meanwhile, intraperitoneal (i.p.) injection of the hydrocarbon oil pristane into normal mice leads to a lupus-like autoimmune syndrome. We aimed to investigate the effects of curcumin on systemic lupus erythematosus (SLE) clinical manifestation, adaptive immune system components, proinflammatory cytokines, and autoantibody production in pristane-induced lupus mice. …”
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Healthcare Utilization and Costs Among US Adolescents With Alopecia Areata by Markqayne Ray, Elyse Swallow, Kavita Gandhi, Christopher Carley, Vanja Sikirica, Travis Wang, Nicolae Done, James Signorovitch, Arash Mostaghimi

“…**Background:** Alopecia areata (AA) is an autoimmune disease of hair loss affecting people of all ages. …”
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Serum calprotectin and renal function decline in ANCA-associated vasculitides: a post hoc analysis of MAINRITSAN trial by Xavier Romand, Benjamin Terrier, Athan Baillet, Philippe Gaudin, Loic Guillevin, Christian Pagnoux, Minh Vu Chuong, Marie Hélène Paclet

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The Role of Pyroptosis‐Related Gene Signature and Immune Infiltration in Juvenile Dermatomyositis by Qiao W, Zhu C, Huang D, Liu Y, Wang Z, Zhu T, Song Q, Yang X, Wang Y, Wang Y

“…Weizhou Qiao,1,* Cuiping Zhu,2,* Dan Huang,1 Yue Liu,1 Zengkai Wang,1 Tianjie Zhu,1 Qingyu Song,1 Xu Yang,1 Yueying Wang,1 Yushuang Wang1 1Department of Clinical Laboratory, Central Hospital of Dalian University of Technology, Dalian, 116033, People’s Republic of China; 2Blood Purification Center, Central Hospital of Dalian University of Technology, Dalian, 116033, People’s Republic of China*These authors contributed equally to this workCorrespondence: Weizhou Qiao, Department of Clinical Laboratory, Central Hospital of Dalian University of Technology, No. 826, Southwest Road, Shahekou District, Dalian, Liaoning, 116033, People’s Republic of China, Email qiaoweizhou2024@163.comObjective: Juvenile dermatomyositis (JDM) is a complex autoimmune disease, and its pathogenesis remains poorly understood. …”
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Severe Guillain-Barré syndrome with concurrent optic neuritis in a pediatric patient: a case report by Xin Xue, Yingcun Bao, Yakun Yu, Qun Li, Mei Liu, Xiaoling Li

“…It also underscores the need for awareness of overlapping central and peripheral autoimmune neuropathies to improve diagnostic accuracy and patient outcomes.…”
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Real-world clinical experience with secukinumab in psoriatic arthritis: an observational study and a literature review by Eleonora Celletti, Giulio Gualdi, Emanuela Sabatini, Francesco Cipollone, Fabio Lobefaro, Paolo Amerio

“…The major comorbidities recorded were fibromyalgia (33% of patients), recurrent bilateral anterior uveitis, and autoimmune thyroiditis with hypothyroidism (both 13% of the patients). …”
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Targeting NF-kappaB-inducing kinase shapes B-cell homeostasis in myasthenia gravis by Xiaoyu Huang, Zhouao Zhang, Zhouyi Wang, Tiancheng Luo, Mingjin Yang, Xinyan Guo, Xue Du, Tianyu Ma, Yong Zhang

“…In vitro and in vivo, the effects of NIK inhibitor (B022) on the function of CD19+B cells and CD4+T cells were detected under the MG PBMCs, sorted B cells and experimental autoimmune MG (EAMG) rat model, respectively. Results The expression levels of NIK were upregulated in CD19+B cells, CD4+T cells and serum from new-onset MG patients. …”
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Global analysis of influenza epidemic characteristics in the first two seasons after lifting the nonpharmaceutical interventions for COVID-19 by Xiaowei Chen, Honghong Chen, Fangfang Tao, Yinzi Chen, Ying Zhou, Jian Cheng, Xiling Wang

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Synergistic Effects of Extra X Chromosome on Development of Systemic Lupus Erythematosus and Sjögren Disease in Klinefelter and Triple X Syndrome: A Retrospective Cohort Study by Anna‐Kay Palmer, Irene J. Tan

“…Objective Systemic lupus erythematosus (SLE) and Sjögren disease (SjD) are autoimmune diseases with significant female predominance. …”
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Soluble Markers of Antibody Secreting Cell Function as Predictors of Infection Risk in Rheumatoid Arthritis by Maria J. Gutierrez, Stephen V. Desiderio, Nae-Yuh Wang, Erika Darrah, Laura Cappelli, Gustavo Nino, Michelle Jones, Clifton O. Bingham

“…Rheumatoid arthritis (RA) is a systemic autoimmune disease associated with immune dysregulation and increased risk of infections. …”
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NLRX1 limits inflammatory neurodegeneration in the anterior visual pathway by Alexander J. Gill, Matthew D. Smith, Danny Galleguillos, Thomas Garton, Jackson W. Mace, Sachin P. Gadani, Swati Kumar, Aayush Pokharel, Krista Solem, Saahith Potluri, Omar Hussein, Giuliana Sardi Rogines, Arihant Singh, Annatje Clark, Peter A. Calabresi, Marjan Gharagozloo

“…Using multiple experimental autoimmune encephalomyelitis (EAE) models, we discovered that NLRX1 protects neurons in the anterior visual pathway from inflammatory neurodegeneration. …”
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Developing a Label-Free Infrared Spectroscopic Analysis with Chemometrics and Computational Enhancement for Assessing Lupus Nephritis Activity by Mei-Ching Yu, Xiang-Di Huang, Chin-Wei Kuo, Kai-Fu Zhang, Ping-Chung Liang, U-Ser Jeng, Pei-Yu Huang, Frederick Wai Keung Tam, Yao-Chang Lee

“…Patterns of disease and therapeutic responses vary widely among patients with autoimmune glomerulonephritis. This study introduces groundbreaking personalized infrared (IR)-based diagnostics for real-time monitoring of disease status and treatment responses in lupus nephritis (LN). …”
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The absolute number of circulating Treg cells is reduced in difficult-to-treat RA patients and is ameliorated by low-dose IL-2 by Huanhuan Yan, Huanhuan Yan, Huanhuan Yan, Xiaoyu Zi, Xiaoyu Zi, Xiaoyu Zi, Huer Yan, Xiaoying Zhang, Xiaoying Zhang, Xiaoying Zhang, Jie Bai, Jie Bai, Jie Bai, Chong Gao, Xiaofeng Li, Xiaofeng Li, Xiaofeng Li, Caihong Wang, Caihong Wang, Caihong Wang

“…Low-dose interleukin-2 (IL-2) has been considered for the treatment of autoimmune diseases. This study focused on the uniqueness of D2T RA lymphocyte subsets and the feasibility of low-dose IL-2 therapy.MethodsParticipants included 1,042 RA patients who were divided into three groups according to the presence or absence of treatment and their response to treatment in the last 6 months—new group, treated group, and D2T group—and 339 healthy controls (HCs). …”
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