Analytical validation of a novel bioassay for thyroid-stimulating immunoglobulin by Paul D. Olivo, Hannah Kim, Lynn Miao, Jeffery A. Houtz, George J. Kahaly

“…The Turbo TSI bioassay demonstrated 95.2% (95% CI 83.3-98.1) positive percent agreement and 94.8% (95% CI 90.9-97.1) negative percent agreement with an FDA-cleared bioassay (Thyretain® TSI) using serum from 295 patients with autoimmune thyroid disease.ConclusionsThe Turbo TSI bioassay exhibits excellent analytical performance and a high level of reproducibility. …”
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Pharmacological Inhibition of Glutaminase 1 Normalized the Metabolic State and CD4+ T Cell Response in Sjogren’s Syndrome by Jiayao Fu, Yiping Pu, Baoli Wang, Hui Li, Xiujuan Yang, Lisong Xie, Huan Shi, Zhijun Wang, Junhao Yin, Tianle Zhan, Yanxiong Shao, Changyu Chen, Qi Luo, Jiabao Xu, Zirui Zong, Xindi Wei, Wanwen Xiao, Chuangqi Yu, Lingyan Zheng

“…Previous studies have shown that abnormal metabolic reprogramming in CD4+ T cells could explain the occurrence of several autoimmune disorders, including Sjogren’s syndrome (SS). …”
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Oxypeucedanin hydrate alleviates rheumatoid arthritis by inhibiting the TLR4-MD2/NF-κB/MAPK signaling axis by Liu Mengdan, Huo Xueyan, Li Congcong, Hu Yunjie, Lei Haoran, Wang Dong, Zhu Lin, Gu Yucheng, Guo Dale, Huang Lijun, Deng Yun

“…Rheumatoid arthritis (RA) is an idiopathic and chronic autoimmune disease for which there are currently no effective treatments. …”
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Levels of Pathogenic Th17 and Th22 Cells in Patients with Rheumatoid Arthritis by Marlen Vitales-Noyola, Berenice Hernández-Castro, Diana Alvarado-Hernández, Lourdes Baranda, Sofía Bernal-Silva, Carlos Abud-Mendoza, Perla Niño-Moreno, Roberto González-Amaro

“…Rheumatoid arthritis (RA) is a chronic autoimmune condition characterized, among others, by tissue damage and activation/differentiation of proinflammatory lymphocytes. …”
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Confounding Risk Factors in Developing Type 1 Diabetes Mellitus among Children and Adolescents at Sulaimani Chronic Diabetes Health Center by Pary Mohammad Azize, Chia H. Sadiq

“…Residency and Family history of autoimmune disease were ranked in the fifth line of factor, finally the weakest factor is nationality by total variance of 8.552%. …”
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Increased Fas and Bcl-2 Expression on Peripheral Blood T and B Lymphocytes from Juvenile-Onset Systemic Lupus Erythematosus, but not from Juvenile Rheumatoid Arthritis and Juvenile... by Bernadete L. Liphaus, Maria H. B. Kiss, Solange Carrasco, Claudia Goldenstein-Schainberg

“…Defective regulation of apoptosis may play a role in the development of autoimmune diseases. Fas and Bcl-2 proteins are involved in the control of apoptosis. …”
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AMPD1 and MTHFR genes are not associated with calcium levels in rheumatoid arthritis patients with methotrexate therapy in Indonesia by Dika P. Destiani, Sumartini Dewi, Syed A. S. Sulaiman, Sofa D. Alfian, Melisa I. Barliana, Rizky Abdulah

“…Abstract Rheumatoid Arthritis (RA) is a chronic and progressive autoimmune disease that affects synovial tissues has greater risk of developing secondary osteoporosis (OP). …”
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Strengths of pelvic floor muscles in women with multiple sclerosis and its relationship with urinary incontinence and quality of life by Poorandokht Afshari, Parvin Abedi, Nastaran Majdinasab, Samaneh Tafakh, Mohammadhossein Haghighizadeh

“…BackgroundMultiple sclerosis (MS) is a debilitating autoimmune disease that mostly affects women.ObjectivesIn this study we evaluated the relationship of pelvic muscle strengths with urinary incontinence and quality of life in women with MS.Materials and methodsIn this cross-sectional study 87 women with MS were recruited. …”
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An Unusual Presentation of Glandular Fever by Dominic Worku, Li Hui Chang, Ian Blyth

“…Admission liver function tests, coeliac serology, autoimmune panel (ANA, ANCA, and anti-dsDNA), hepatitic (hepatitis A, B, and E), human immunodeficiency virus (HIV), toxoplasmosis, parvovirus, and CMV serology were normal. …”
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Correlation Between Vitamin D3 Levels, Autoantibodies, and Antibody-Related Diseases in Patients with Hashimoto's Thyroiditis by Ali Saad Kadhim, Abdullah Salim Al-Karawi

“…In this disorder, several autoantibodies play an essential role in the dysfunction of the thyroid, including the metabolism of 1,25-dihydroxyvitamin D3 (1,25 VitD3)-XP, and leading to contributed to the development of related autoimmune diseases. The aim of current study to explore the important correlation between 1,25 VitD3 deficiency and specific types of autoantibodies in the patients. …”
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Cryptogenic Organizing Pneumonia with a Rare Radiographic Presentation of a Diffuse Micronodular Pattern Mimicking Miliary Lung Infiltration: A Case Report and Review of the Litera... by Jakrin Kewcharoen, Kittika Poonsombudlert, Sakda Sathirareuangchai, Wichit Sae-Ow, Hanh La, Narin Sriratanaviriyakul

“…His final culture results, microbiological data and serology workup for autoimmune disease were all unremarkable. The patient was diagnosed with COP and was started on systemic corticosteroids. …”
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Combination of Gilbert's syndrome and gastrointestinal diseases by G. M. Dubrovina, O. K. Botvinyev, A. I. Kolotilina

“…The protective role of unconjugated bilirubin in relation to various diseases - cardio-vascular, autoimmune, oncologic is studied.Conclusion. The reasons of development of symptoms related to gastro-intestinal organs in patients with Gilbert's syndrome are investigated insufficiently. …”
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EXamining the feasibility of exerCisE to manage symptoms of Lupus (EXCEL): a protocol for a randomised controlled pilot study by John Reynolds, Katie Hesketh, Matthew Cocks, Megan Quickfall, Alex J Wadley, Scott Green, Jet Veldhuijzen Van Zanten

“…Introduction SLE is a chronic autoimmune disease that results in sustained hyperactivation of innate and adaptive immune cells and widespread inflammatory damage. …”
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Circulating CD3+HLA-DR+ Extracellular Vesicles as a Marker for Th1/Tc1-Type Immune Responses by Ryutaro Oba, Motomichi Isomura, Akira Igarashi, Kinya Nagata

“…The results suggest that these EV subpopulations reflect in vivo activation status of total CD4+, total CD8+, and Th1/Tc1-type T cells, respectively, and may be helpful in T cell-related clinical settings, such as cancer immunotherapy and treatment of chronic infection, autoimmune diseases, and graft-versus-host disease.…”
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Comorbidity in in patients with relapsing-remitting multiple sclerosis by O.V. Somilo, S.O. Makarov, O.I. Kalbus

“…Multiple sclerosis is a chronic autoimmune inflammatory disease that affects the brain and spinal cord. …”
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The potential of stem cell therapy in Multiple Sclerosis treatment: a review by Sorina Amarculesei, Ava O'Meara Cushen, Cathy Brougham

“…Multiple Sclerosis is an autoimmune and neurodegenerative disease of the central nervous system. …”
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Disruption of Gut Microbiota and Associated Fecal Metabolites in Collagen-Induced Arthritis Mice During the Early Stage by Wu D, Yin M, Cao D, Zhang X, Zhu Y, Wei Y, Li Y, Wen C, Zhou J

“…Dehong Wu,1,* Mengdi Yin,2,* Dandan Cao,2,* Xiafeng Zhang,2 Yichun Zhu,2 Ying Wei,2 Yiling Li,2 Chengping Wen,2 Jia Zhou2 1Department of Rheumatology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310005, People’s Republic of China; 2Institute of Basic Research in Clinical Medicine, College of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, 310053, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jia Zhou; Chengping Wen, Email zhoujia@zcmu.edu.cn; chengpw2010@126.comBackground: Rheumatoid arthritis (RA) is a chronic autoimmune disease and increasing evidence suggests that disturbances in the composition and function of gut microbiota are potentially implicated in the progression of RA. …”
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Development of a Conceptual Model to Understand Disease Burden in Patients With Systemic Lupus Erythematosus and Organ Damage by Lynne Broderick, Wen-Hung Chen, Roger A. Levy, April Mitchell Foster, Cindy Umanzor Figueroa, Kerry Gairy, Deven Chauhan

“…**Background:** Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can lead to irreversible organ damage (OD). …”
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Influence of Cosmetic Skincare Products with pH < 5 on the Skin Microbiome: A Randomized Clinical Evaluation by Ciska Janssens-Böcker, Claudia Doberenz, Marta Monteiro, Marta de Oliveira Ferreira

“…Disruptions to the skin microbiome can impact immune function, leading to inflammatory and autoimmune conditions. The importance of pH for the microbiome is paramount. …”
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Exploring Clec9a in dendritic cell-based tumor immunotherapy for molecular insights and therapeutic potentials by Zubair Hussain, Yueteng Zhang, Lu Qiu, Shanshan Gou, Kangdong Liu

“…These effects include the enhancement of the cDC1s cross-presentation, reducing autoimmune responses and systemic inflammation, as well as preventing the non-specific activation of other immune cells. …”
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