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1381
Comprehensive Enteroviral Serology Links Infection and Anti‐Melanoma Differentiation‐Associated Protein 5 Dermatomyositis
Published 2025-01-01“…Objective Idiopathic inflammatory myopathies (IIMs) are a group of heterogeneous, systemic autoimmune diseases characterized by specific clinical features and, frequently, skeletal muscle inflammation. …”
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1382
Anti-ribosomal P2: could it be a useful new criterion for patients with systemic lupus erythematosus?
Published 2025-01-01“…Abstract Background Systemic lupus erythematosus is a multisystem autoimmune disorder that displays numerous autoantibodies such as anti-nuclear, anti-Smith, anti-double-stranded DNA, and anti-ribosomal antibodies. …”
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1383
Th17 Cell Enhances CD8 T-Cell Cytotoxicity via IL-21 Production in Emphysema Mice
Published 2012-01-01“…Emphysema is a T-cell mediated autoimmune disease caused predominantly by cigarette smoking. …”
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1384
Clinical Outcomes in Patients with Cardiac Lupus: A Retrospective Study
Published 2020-01-01“…Objectives: Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect every organ system. …”
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1385
Correction of Hypothyroidism Seems to Have No Effect on Body Fat
Published 2013-01-01“…Forty-two women with naive autoimmune hypothyroidism were included. Also, 40 healthy participants were enrolled as a control group. …”
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1386
Efficacy of CLT4A variants as immunoregulatory molecules among Vitiligo patients in Saudi Arabia
Published 2025-02-01“…The Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4) gene has been reported to be related to vitiligo and other autoimmune diseases. The purpose of this study was to explore the molecular involvement of rs231775 and rs3087243 SNPs in the CTLA4 gene in vitiligo patients. …”
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1387
A minimal mathematical model for the initial molecular interactions of death receptor signalling
Published 2012-06-01“…TNF itself is a strong proinflammatory regulator of the innate immune system, but has been also recognized as a major factor in progression of autoimmune diseases. A subgroup of the TNF ligand family, including TNF, signals via so-called death receptors, capable to induce a major form of programmed cell death, called apoptosis. …”
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1388
Topical steroids as alternative to systemic hormonal treatment for inflammatory bowel diseases in pediatric practice
Published 2011-05-01“…Etiopathogenesis of IBD represents the cascade of self-maintaining pathophysiological reactions: adaptive microcirculational, hypoxicmetabolic, autoimmune inflammatory and dysbiotic disorders emerging on a background of genetic features of the body under the effect of unfavorable environmental factors. …”
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1389
Rheumatoid Arthritis Effects on Kidney and Liver and their Correlations with CDAI
Published 2022-11-01“… Rheumatoid arthritis (RA) is a disease characterized by chronic autoimmune inflammation of body joints, causing movement disability, loss of functions, joint damage, and many complications. …”
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1390
New treatment options for generalized myasthenia gravis
Published 2024-02-01“…Myasthenia gravis is an autoimmune disease in which autoantibodies against the postsynaptic membrane proteins of the neuromuscular junction disrupt impulse transmission thus causing pathological muscle weakness and fatigue that worsens throughout the day. …”
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1391
Enhancing Mesenchymal Stromal Cell Immunomodulation for Treating Conditions Influenced by the Immune System
Published 2019-01-01“…Thus, immunosuppressive treatment with MSCs has been proposed as a potential therapeutic alternative for conditions in which the immune system cells influence outcomes, such as inflammatory and autoimmune diseases. The precise mechanism by which MSCs affect functions of most immune effector cells is not completely understood but involves direct contact with immune cells, soluble mediators, and local microenvironmental factors. …”
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1392
Manifestaciones bucales de la enfermedad celíaca en pacientes geriátricos consumidores de gluten
Published 2024-09-01“…<p><strong>Foundation</strong>: Celiac disease is a chronic inflammatory and autoimmune disease that affects genetically susceptible individuals due to a permanent intolerance to gluten. …”
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1393
Graves’ ophthalmopathy: the clinical and psychosocial outcomes of different medical interventions – a systematic review
Published 2024-05-01“…Background Graves’ ophthalmopathy is a complex autoimmune disorder that can significantly affect quality of life (QoL), vision and physical appearance. …”
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1394
Evaluation of Clinical Interest of Anti-Aquaporin-4 Autoantibody Followup in Neuromyelitis Optica
Published 2013-01-01“…Neuromyelitis optica (NMO) is an autoimmune disease in which a specific biomarker named NMO-IgG and directed against aquaporin-4 (AQP4) has been found. …”
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1395
Multidose Streptozotocin Induction of Diabetes in BALB/c Mice Induces a Dominant Oxidative Macrophage and a Conversion of TH1 to TH2 Phenotypes During Disease Progression
Published 2005-01-01“…The aim of this study is to investigate the redox status of peritoneal Mp and its cytokine profile during the development of autoimmune diabetes induced by multiple low-dose streptozotocin in BALB/c mice. …”
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1396
Inhibitory Effects of iPSC-MSCs and Their Extracellular Vesicles on the Onset of Sialadenitis in a Mouse Model of Sjögren’s Syndrome
Published 2018-01-01“…No effective treatment for Sjögren’s syndrome (SS), a chronic autoimmune disease affecting mainly salivary and lacrimal glands, is available now. …”
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1397
Pharmacological insights and therapeutic advances of mangiferin against various pathological conditions in liver diseases
Published 2025-03-01“…Currently, liver diseases have become a serious global health issue, and this situation occurs due to the exposure of the liver to different agents, such as chemicals, alcohol, viruses, and autoimmune diseases. Mangiferin is a natural bioactive xanthone C-glycoside compound and a potent antioxidant that is widely found in medicinal plants such as the leaves of Mangifera indica L. …”
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1398
Hydroxysafflor Yellow A Inhibits LPS-Induced NLRP3 Inflammasome Activation via Binding to Xanthine Oxidase in Mouse RAW264.7 Macrophages
Published 2016-01-01“…Hydroxysafflor yellow A (HSYA) is an effective therapeutic agent for inflammatory diseases and autoimmune disorders; however, its regulatory effect on NLRP3 inflammasome activation in macrophages has not been investigated. …”
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1399
How do serum cytokine levels change in myocarditis and inflammatory dilated cardiomyopathy relative to healthy individuals? A protocol for a systematic review and meta-analysis
Published 2025-02-01“…Introduction Myocarditis is an inflammatory heart disease resulting from infections, toxic exposures or autoimmune reactions. Irrespective of the factors responsible for this disease, cytokines play an important role in regulating the immunological response involved in its development and progression. …”
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1400
Adipose Tissue-Derived Mesenchymal Stem Cells Exert In Vitro Immunomodulatory and Beta Cell Protective Functions in Streptozotocin-Induced Diabetic Mice Model
Published 2015-01-01“…Thus, we proposed in vitro assessment of adipose tissue-derived MSCs (AT-MSCs) immunomodulation on autoimmune response along with beta cell protection in streptozotocin- (STZ-) induced diabetic C57BL/6 mice model. …”
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