Idiopathic Thrombocytopenic Purpura after Mastectomy and Axillary Lymph Node Dissection by Wil L. Santivasi, Meghan M. Routt, Alicia M. Terando

“…First described in 1916, idiopathic thrombocytopenic purpura (ITP) is an autoimmune disease resulting in the destruction of platelets. …”
Get full text

A Case of Systemic Lupus Erythematosus Presenting as Guillain-Barré Syndrome by Helen Chioma Okoh, Sandeep Singh Lubana, Spencer Langevin, Susan Sanelli-Russo, Adriana Abrudescu

“…Systemic lupus erythematosus (SLE) is an autoimmune systemic disease with multiple organ involvement with high morbidity and mortality rate. …”
Get full text

The changing landscape of treatment for acquired hemophilia A by Massimo Franchini, Daniele Focosi

“… Acquired hemophilia A (AHA) is a rare acquired autoimmune disorder caused by autoantibodies against coagulation factor VIII (FVIII), which cause a hemorrhagic diathesis, not rarely of severe degree. …”
Get full text

A Case Report of Steroid-Resistant Cryptogenic Organizing Pneumonia Managed with Intravenous Immunoglobulins by Christian Akem Dimala, Urvi Patel, Benjamin Lloyd, Anthony Donato, William B. Kimmel, Robert Hallowell, Caitlyn Moss

“…Following no improvement with antibiotics and negative complementary investigations for infectious, malignant, and autoimmune etiologies, COP was confirmed on lung biopsy. …”
Get full text

18F-FDG PET/CT findings of erythema induratum by KyungAh Chun, MD, PhD

“…18F-FDG (fluorodeoxyglucose) accumulates in malignant tissues but also at the sites of infection and inflammation and in autoimmune and granulomatous diseases by the overexpression of distinct facultative glucose transporter (GLUT) isotypes (mainly GLUT-1 and GLUT-3) in cancer cells and inflammatory cells.A 75-year-old female with a history of skin rash with tenderness for 1 month underwent 18F-FDG positron emission tomography/computed tomography (PET/CT) to determine the presence of an underlying disease including malignant tumor. …”
Get full text

Characteristics of Sjögren’s syndrome associated with rheumatoid arthritis by Xavier Mariette, Raphaele Seror, Gaetane Nocturne, Nolan Hassold

Get full text

Circulating (CD3−CD19+CD20−IgD−CD27highCD38high) Plasmablasts: A Promising Cellular Biomarker for Immune Activity for Anti-PLA2R1 Related Membranous Nephropathy? by Agnieszka Pozdzik, Ingrid Beukinga, Chunyan Gu-Trantien, Karen Willard-Gallo, Joëlle Nortier, Olivier Pradier

“…Membranous nephropathy (MN) is a kidney specific autoimmune disease mainly mediated by anti-phospholipase A2 receptor 1 autoantibody (PLA2R1 Ab). …”
Get full text

Blood Genomics Identifies Three Subtypes of Systemic Lupus Erythematosus: “IFN-High,” “NE-High,” and “Mixed” by Mintian Cui, Taotao Li, Xinwei Yan, Chao Wang, Qi Shen, Hongbiao Ren, Liangshuang Li, Ruijie Zhang

“…Systemic lupus erythematosus (SLE) is a systemic and multifactorial autoimmune disease, and its diverse clinical manifestations affect molecular diagnosis and drug benefits. …”
Get full text

Chronic Atrophic Gastritis Presenting as Hemolytic Anemia due to Severe Vitamin B12 Deficiency by Amanda M. Woodford, Rabhea Chaudhry, Gabriella A. Conte, Varsha Gupta, Madhurima Anne

“…Such causes include achlorhydria, gastritis, gastrectomy, or the use of PPIs or antacids. A rarer cause is autoimmune chronic atrophic gastritis, resulting in pernicious anemia. …”
Get full text

Impact of Cyclosporine A on Cognitive Functions and Neuronal Oxidative Stress, Apoptosis and Inflammatory Markers in Rats by Awyed Batah Almutairi, Abdulaziz Arif A. Alshammari, Arshad Husain Rahmani, Ali Yousif Babiker, Long Chiau Ming, Maha A. Aldubayan, Ahmad H. Alhowail, Vasudevan Mani

“… Cyclosporine A (CYP-A), a potent immunosuppressive agent, significantly impacts organ transplantation and the treatment of autoimmune disorders, and its ability to control autoimmune reactions and prevent organ rejection has made it indispensable in contemporary medicine. …”
Get full text

Citrullinated IGF2BP1 promotes rheumatoid synovial aggression via increasing the mRNA stability of SEMA3D by Yang Qin, Li Liu, Yanwen Zhang, Xiaowei Chen, Jiani Zhang, Sunwang Ling, Jianguang Wang, Xinyu Yang

Get full text

Clinical Correlations of Novel Autoantibodies in Patients with Dry Eye by Sezen Karakus, Alan N. Baer, Esen K. Akpek

“…Whether these patients have an early stage of SS or a different type of autoimmune condition may be determined through longitudinal studies.…”
Get full text

Autoantibodies in type 1 diabetes: Prevalence and clinical profiles by Raja Hazime, Saad Lamjadli, Morad Guennouni, Mounir Belkrachni, Fatima-Ezzohra Eddehbi, Ider Oujamaa, Lahcen Elmoumou, Aicha Bourrahouate, Imane Ait Sab, Hicham Baizri, Nawal El Ansari, Brahim Admou

“…Identifying autoantibodies can help predict the onset of T1D and associated autoimmune disorders, enhancing patient management strategies.We aimed to determine the prevalence of T1D autoantibodies and their clinical significance in the pediatric and adult populations. …”
Get full text

ImmunoglobuliN in the Treatment of Encephalitis (IgNiTE): protocol for a multicentre randomised controlled trial by R Kneen, M Lim, A Vincent, A J Pollard, W K Chong, L-M Yu, M A Iro, M Sadarangani, M Absoud, C A Clark, A Easton, V Gray, M Pike, T Solomon, L Willis

“…Safety, radiological, other autoimmune and tertiary outcomes will also be assessed.Ethics and dissemination This trial has been approved by the UK National Research Ethics committee (South Central—Oxford A; REC 14/SC/1416). …”
Get full text

Anti-PL-7/PL-12 antisynthetase syndrome associated with interstitial lung disease following SARS-COV-2 infection and vaccination: A case study review by Laura García-Bravo, Ángela Villegas, Bárbara López Uceda, Anaís Mariscal, Cristina Vadillo, M Asunción Nieto Barbero, Juan Luis Rodríguez-Hermosa, Beatriz Mediero Valeros, José Carlos Plaza-Hernández, Miguel Fernández-Arquero, María Guzmán-Fulgencio, Gloria Candelas-Rodríguez, Silvia Sánchez-Ramón, Juliana Ochoa-Grullón

“…Cumulative evidence suggests a link between specific autoimmune diseases (AD), including idiopathic inflammatory myopathies (IIM), and SARS-CoV-2 infection or COVID-19 vaccination. …”
Get full text

Pure White Cell Aplasia and Necrotizing Myositis by Peter Geon Kim, Joome Suh, Max W. Adelman, Kwadwo Oduro, Erik Williams, Andrew M. Brunner, David J. Kuter

“…PWCA has been associated with autoimmune, drug-induced, and viral exposures. Here, we report a case of a 74-year-old female who presented with severe proximal weakness without pain and was found to have PWCA with nonspecific inflammatory necrotizing myositis and acute liver injury on biopsies. …”
Get full text

Umbilical Cord-Derived Mesenchymal Stem Cells Suppress Autophagy of T Cells in Patients with Systemic Lupus Erythematosus via Transfer of Mitochondria by Jinyun Chen, Qian Wang, Xuebing Feng, Zhuoya Zhang, Linyu Geng, Ting Xu, Dandan Wang, Lingyun Sun

“…Aberrant autophagy played an important role in the pathogenesis of autoimmune diseases, especially in systemic lupus erythematosus (SLE). …”
Get full text

Henoch-Schönlein Purpura with Adalimumab Therapy for Ulcerative Colitis: A Case Report and Review of the Literature by Joseph J. LaConti, Jean A. Donet, Jeong Hee Cho-Vega, Daniel A. Sussman, Dana Ascherman, Amar R. Deshpande

“…We review similar cases reported in the literature and discuss the consequences of these autoimmune diseases.…”
Get full text

Stauffer’s Syndrome in Patient with Metastatic Prostate Cancer by Andris Romašovs, Aldis Puķītis, Viktorija Mokricka, Elina Frolova

“…Cholestasis is a symptom that can be present in many conditions, such as bile duct obstruction by malignant mases, obstruction by gallstone, acute and chronic viral hepatitis, and autoimmune disorders, such as primary biliary and sclerosing cholangitis. …”
Get full text

Case report: Testicular manifestation of ANCA vasculitis by Noah J. Sandel, Henry Wielzen

“…ANCA-associated vasculitis is a rare autoimmune disorder affecting small to medium-sized vessels, often targeting the respiratory tract and kidneys. …”
Get full text