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561
The Expansion of CD25highIL-10highFoxP3high B Regulatory Cells Is in Association with SLE Disease Activity
Published 2015-01-01“…B regulatory cells (Bregs) belong to a subgroup of activated B cells tasked with maintaining self-tolerance and preventing autoimmunity. While sharing similar regulatory mechanisms such as IL-10 dependency, they also defer in exhibiting their suppressive effects by expressing Fas-Ligand, TGF-beta, and PDL-1. …”
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562
cGAS-STING targeting offers therapy choice in lung diseases
Published 2025-02-01“…However, chronic and aberrant activation of the cGAS-STING axis results in inflammatory and autoimmune diseases. cGAS-STING has emerged as a vital mechanism driving inflammation-related diseases, including lung diseases. …”
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563
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564
Radiological Patterns of Lung Involvement in Inflammatory Bowel Disease
Published 2018-01-01“…The common embryonic origin of intestine and lungs from the foregut, autoimmunity, smoking, and bacterial translocation from the colon may all be involved in the pathogenesis of these manifestations in IBD patients. …”
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565
Toll-like receptors in atopic dermatitis: pathogenesis and therapeutic implications
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566
Development and Evaluation of an In-House ELISA to Detect Anti-FcεR1α IgG Autoantibodies in Chronic Spontaneous Urticaria Patients
Published 2022-01-01“…Association between chronic spontaneous urticaria (CSU) and autoimmunity has been well documented. Autologous serum skin testing could support the autoimmune etiology of CSU, whereas it is difficult to interpret and could not be performed on antihistamine omitted patients. …”
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567
Large-Scale Screening in General Population Children for Celiac Disease with a Multiplex Electrochemiluminescence (ECL) Assay
Published 2020-01-01“…Background. Autoimmunity Screening for Kids (ASK) study was launched to screen general population children for type 1 diabetes (T1D) and celiac disease (CD). …”
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568
The Association of TNF-Alpha Inhibitors and Development of IgA Nephropathy in Patients with Rheumatoid Arthritis and Diabetes
Published 2020-01-01“…Discontinuation of anti-TNF-alpha therapy and initiation of immunosuppressive therapy led to improvement in serologic abnormalities and renal function in two patients, while the third patient’s 24-hour proteinuria was only partially reduced, which supports previous reports on TNF-alpha inhibitor induced autoimmunity. Two of our patients had previously been diagnosed with type 2 diabetes mellitus while the third patient developed diabetes years after the onset of IgAN. …”
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569
Roitt's essential immunology /
Published 2017Table of Contents: “…Innate immunity -- Specific acquired immunity -- Antibodies -- Membrane receptors for antigen -- Antigen-specific recognition -- Immunological methods and applications [JS2] -- The anatomy of the immune response -- Lymphocyte activation -- The production of effectors -- The regulation of the immune response -- Development and evolution of the immune response -- Adversarial strategies during infection -- Vaccines -- Immunodeficiency -- Allergy and other hypersensitivities -- Transplantation -- Tumor immunology -- Autoimmune diseases.…”
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Electronic eBook -
570
Why is it so difficult to understand why we don’t understand human systemic lupus erythematosus? Contemplating facts, conflicts, and impact of “the causality cascade paradigm”...
Published 2025-01-01“…Classification criteria, autoimmunity, DNA structures, and anti-dsDNA antibodies are integrated aspects in this discussion.…”
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571
Circulating Visfatin in Hypothyroidism Is Associated with Free Thyroid Hormones and Antithyroperoxidase Antibodies
Published 2016-01-01“…The autoimmune study group (AIT) consisted of 39 patients newly diagnosed with hypothyroidism in a course of chronic autoimmune thyroiditis. …”
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572
lncRNA IGHCγ1 Acts as a ceRNA to Regulate Macrophage Inflammation via the miR-6891-3p/TLR4 Axis in Osteoarthritis
Published 2020-01-01“…Accumulating data have implicated that long noncoding RNA (lncRNA) plays an important role in osteoarthritis (OA), which may function as a competitive endogenous RNA (ceRNA) of microRNAs (miRNAs). lncRNA IGHCγ1 has been demonstrated to regulate inflammation and autoimmunity. Nonetheless, the altering effect of IGHCγ1 in OA remains unclear. …”
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573
Towards a Vaccine Against Rheumatic Fever
Published 2006-01-01“…Rheumatic fever (RF) is an autoimmune disease which affects more than 20 million children in developing countries. …”
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574
B7-H4 Pathway in Islet Transplantation and β-Cell Replacement Therapies
Published 2011-01-01“…The two main obstacles after islet transplantation are alloreactive T-cell-mediated graft rejection and recurrence of autoimmune diabetes mellitus in recipients. T cells play a central role in determining the outcome of both autoimmune responses and allograft survival. …”
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575
Inborn Errors of Immunity Presenting with Early-Onset Severe Atopy
Published 2025-01-01“…Additionally, we discuss the importance of recognizing such severe atopy as a potential indicator of an underlying immune deficiency, particularly when accompanied by unusual infections, growth failure, or autoimmunity. This review aims to raise awareness of this association and emphasize the need for early diagnosis and genetic testing in patients with atypical or treatment-resistant allergic diseases, allowing for more timely diagnosis of underlying immunodeficiencies and appropriate treatments.…”
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576
In Vitro Effects of Some Botanicals with Anti-Inflammatory and Antitoxic Activity
Published 2016-01-01“…Several extrinsic factors, like drugs and chemicals, can foster autoimmunity. Tetracyclines, in particular oxytetracycline (OTC), appear to correlate with the emergence of immune-mediated diseases. …”
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577
Genetic insight into dissecting the immunophenotypes and inflammatory profiles in the pathogenesis of Sjogren syndrome
Published 2025-01-01“…Abstract Background Sjogren syndrome (SS) is a chronic systemic autoimmune disease and its pathogenesis often involves the participation of numerous immune cells and inflammatory factors. …”
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578
Breg Cells in Celiac Disease Isolated or Associated to Hashimoto’s Thyroiditis
Published 2018-01-01“…The behavior of Th17 subset in patients with celiac disease associated with HT might have been sensitive to the effect of long-lasting GFD, and it is essentially determined by the presence of thyroid autoimmunity.…”
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579
Insights from Dysregulated mRNA Expression Profile of β-Cells in Response to Proinflammatory Cytokines
Published 2022-01-01“…Type 1 diabetes mellitus (T1DM) is a chronic autoimmune disease that is characterized by autoimmunity and its mediated β-cell damage. …”
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580
Differential Production of Midkine and Pleiotrophin by Innate APCs upon Stimulation through Nucleic Acid-Sensing TLRs
Published 2023-01-01“…This highlights the potentially important role of iAPCs in angiogenesis, tumors, infections, and autoimmunity through the differential production of MK and PTN upon TLR triggering.…”
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