Establishing an Electrophysiological Recording Platform for Epidural Spinal Cord Stimulation in Neuropathic Pain Rats by Yang CT, Shyu BC, Lin WT, Lu KH, Lin CR, Wen YR, Chen CC

“…., New Taipei City, Taiwan; 5Department of Anesthesiology, National Cheng Kung University Hospital, Tainan, Taiwan; 6Pain Management and Research Center, Department of Anesthesiology, China Medical University Hospital, Taichung, Taiwan; 7Chun Chuan Orthopedic and Pain Specialty Hospital, Taichung, Taiwan; 8Pain Management Center, Department of Anesthesiology, Jen-Ai General Hospital, Taichung, Taiwan; 9Neuroscience Program of Academia Sinica, Academia Sinica, Taipei, Taiwan; 10Taiwan Mouse Clinic, Biomedical Translational Research Center, Academia Sinica, Taipei, Taiwan*These authors contributed equally to this workCorrespondence: Chih-Cheng Chen; Yeong-Ray Wen, Email chih@ibms.sinica.edu.tw; yray.wen@gmail.comPurpose: Spinal cord stimulation (SCS) is pivotal in treating chronic intractable pain. …”
Get full text

Editorial by Teddy Surya Gunawan

“…We extend our gratitude to the authors, reviewers, and editorial board for their unwavering commitment to excellence. …”
Get full text

Fabrication of Nano-Silver Composite Using Amomum longiligulare Fruit Polysaccharides and Their Biological Activities by Lian Y, Ma N, Cheng Q, Luo M, Xu Z, He F, Zhou X, Zhang Y, Jin D, Kong Y, Wang Y, Wei N

“…Yong Lian,1,* Ning Ma,2,* Qianying Cheng,1,* Mingquan Luo,1 Zhen Xu,1 Fei He,1 Xiaomei Zhou,1 Ying Zhang,1 Dejun Jin,1 Yidan Kong,1 Yong Wang,1 Na Wei1 1Hainan Provincial Key Laboratory of R&D on Tropical Herbs, Engineering Research Center of Tropical Medicine Innovation and Transformation of Ministry of Education, International Joint Research Center of Human-Machine Intelligent Collaborative for Tumor Precision Diagnosis and Treatment of Hainan Province, School of Pharmacy, Hainan Medical University, Haikou, 571199, People’s Republic of China; 2Reproductive Medical Center, Hainan Women and Children’s Medical Center, Haikou, Hainan Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: Na Wei; Yong Wang, Hainan Provincial Key Laboratory of R&D on Tropical Herbs, School of Pharmacy, Hainan Medical University, Haikou, 571199, People’s Republic of China, Email weina-0613@163.com; wangyong1982_2004@163.comPurpose: Study aims to optimize the synthesis conditions for silver nanoparticle composites [ALP(D)-AgNPs] using a rapid and environmentally friendly method and investigate the antioxidant, antibacterial, and anticancer activities of the fabricated composite.Methods: The polysaccharide component ALP-D was extracted and purified from the fruits of Amomum longiligulare and subsequently used for further experiments. …”
Get full text

Barriers and facilitators to facility-based delivery in rural Zambia: a qualitative study of women’s perceptions after implementation of an improved maternity waiting homes interve... by Peter C Rockers, Godfrey Biemba, Davidson H Hamer, Nancy A Scott, Jeanette L Kaiser, Taryn Vian, Rachel M Fong, Thandiwe Ngoma, Jody R Lori, Michelle Munro-Kramer, Misheck Bwalya, Gertrude Musonda, Eden Ahmed Mdluli, Viviane Rutagwera Sakanga, Kayla J Kuhfeldt

Get full text

Effects of Ciprofol and Propofol General Anesthesia on Postoperative Recovery Quality in Patients Undergoing Ureteroscopy: A Randomized, Controlled, Double-Blind Clinical Trial by Shi S, Wu J, Wu Y, Han X, Dai H, Chen X, Sun Z, Wang F

“…Shuqi Shi,1,2,* Jimin Wu,1,* Yini Wu,1 Xin Han,1 Hong Dai,1 Xuedong Chen,3 Zhangnan Sun,4 Faxing Wang1,2 1Department of Anesthesiology, Lishui People’s Hospital, Wenzhou Medical University Lishui Hospital, The First Affiliated Hospital of Lishui University, Lishui, People’s Republic of China; 2Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China; 3Department of Urology, Lishui People’s Hospital, Wenzhou Medical University Lishui Hospital, The First Affiliated Hospital of Lishui University, Lishui, People’s Republic of China; 4Department of Anesthesiology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, People’s Republic of China*These authors contributed equally to this workCorrespondence: Faxing Wang, Department of Anesthesiology, Lishui People’s Hospital, Wenzhou Medical University Lishui Hospital, The First Affiliated Hospital of Lishui University, No. 15, Dazhong Street, Lishui, Zhejiang Province, 323000, People’s Republic of China, Email wfx2023@wmu.edu.cn Zhangnan Sun, Department of Anesthesiology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050000, People’s Republic of China, Email 28703077@hebmu.edu.cnObjective: This study compares postoperative recovery quality between Ciprofol and Propofol, providing a reference for the clinical application of anesthetics.Methods: We randomized 112 patients undergoing ureteroscopic surgery into two groups: the Ciprofol group (Group C), with an induction dose of 0.4 mg/kg and a maintenance dose of 0.8– 1.5 mg/(kg·h), and the Propofol group (Group P), with an induction dose of 2 mg/kg and a maintenance dose of 4– 10 mg/(kg·h). …”
Get full text

Notation publications in the context of musical life in Lithuania in the XVI-XVII centuries by Jūratė Trilupaitienė

“…That a Gregorian chant hymnal was not published until the very middle of the 17th century was largely due to the fact that the Lithuanian Catholic Church was answerable to higher authorities in Poland, which supplied them with most of the liturgical printed material they needed. …”
Get full text

Viral Mimetic Bacterial Outer Membrane Vesicles for Targeting Angiotensin-Converting Enzyme 2 by Ahn G, Yoon HW, Jeong JH, Kim YH, Shin WR, Song MS, Ahn JY

“…Gna Ahn,1,2,* Hyo-Won Yoon,1,* Ju Hwan Jeong,3,4,* Yang-Hoon Kim,1,* Woo-Ri Shin,1,5,6 Min-Suk Song,3 Ji-Young Ahn1 1Department of Microbiology, Chungbuk National University, Cheongju, Republic of Korea; 2Center for Ecology and Environmental Toxicology, Chungbuk National University, Cheongju, Republic of Korea; 3Department of Microbiology, College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea; 4Functional Biomaterial Research Center, Korea Research Institute of Bioscience and Biotechnology, Jeongeup, Republic of Korea; 5Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA; 6Department of Animal Bioscience & Integrated Biotechnology, Gyeongsang National University, Jinju, Republic of Korea*These authors contributed equally to this workCorrespondence: Ji-Young Ahn; Min-Suk Song, Tel +82-43-261-2301 ; +82-43-261-3778, Email jyahn@chungbuk.ac.kr; songminsuk@chungbuk.ac.krPurpose: Outer membrane vesicles (OMVs) derived from Gram-negative bacteria naturally serve as a heterologous nano-engineering platform, functioning as effective multi-use nanovesicles for diagnostics, vaccines, and treatments against pathogens. …”
Get full text

The Association Between Medication Adherence, Internalized Stigma and Social Support Among Outpatients with Major Depressive Disorder in a Malaysian Hospital: A Cross-Sectional Stu... by Halim R, Kaur M, Syed Mokhtar SS, Chemi N, Sajatovic M, Tan YK, Siau CS, Ng CG

“…Rahilah Halim,1,* Manveen Kaur,2,* Sharifah Suziah Syed Mokhtar,1 Norliza Chemi,1 Martha Sajatovic,3 Yee Kee Tan,4 Ching Sin Siau,4 Chong Guan Ng2 1Department of Psychiatry and Mental Health, Hospital Kajang, Kajang, Selangor, Malaysia; 2Psychological Medicine Department, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Wilayah Persekutuan Kuala Lumpur, Malaysia; 3Neurological and Behavioral Outcomes Center, University Hospital Cleveland Medical Center & Case Western Reserve University School of Medicine, Cleveland, OH, USA; 4Centre for Community Health Studies (Reach), Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Wilayah Persekutuan Kuala Lumpur, Malaysia*These authors contributed equally to this workCorrespondence: Manveen Kaur, Psychological Medicine Department, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Wilayah Persekutuan Kuala Lumpur, Malaysia, Email manveen@um.edu.my Ching Sin Siau, Centre for Community Health Studies, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Wilayah Persekutuan, Malaysia, Email chingsin.siau@ukm.edu.myBackground: Internalized stigma and medication non-adherence pose significant challenges for treating major depressive disorder (MDD), leading to disability, increased suicide risk, and morbidity. …”
Get full text

Dietary intakes, food behaviours, and health indicators among Métis youth in Manitoba, Canada by Chantal Perchotte, Olena Kloss, Joyce Slater, Alan Katz, Bhanu Pilli, Aynslie Hinds, Marcelo L Urquia, Julianne Sanguins, Chris Green, Jaime Cidro, Dan Chateau, Nathan Nickel, Thomas Falkenberg

Get full text

Isolation and characterization of novel peptides from fermented products of Lactobacillus for ulcerative colitis prevention and treatment by Dong He, Wen Zeng, Yi Wang, Yifan Xing, Kang Xiong, Nan Su, Chong Zhang, Yuan Lu, Xinhui Xing

Get full text

Improved Efficacy of a Predictive Model for Swallowing-Induced Breakthrough Pain Based on a Redefined Delineation Method in Locally Advanced Nasopharyngeal Carcinoma by Jian-Da Sun, MD, Ze-Kai Chen, MM, Shu-Peng Liu, PhD, Feng Ye, MD, Ting-Xi Tang, MD, Zhen-Hua Zhou, MD, Han-Bin Zhang, MM, Long-Shan Zhang, MD, Ting Xiao, BS, Lin-Lin Xiao, MM, Xiao-Qing Wang, MD, Jian Guan, MD

Get full text

A Nomogram Based on Circulating Inflammatory Factors for Predicting Prognosis of Newly Diagnosed Multiple Myeloma Patients by Wang M, Yue X, Ding Y, Cai Z, Xiao H, Huang H, He J

“…Mowang Wang,1– 4,* Xiaoyan Yue,5,* Yingying Ding,5,* Zhen Cai,1,4 Haowen Xiao,5 He Huang,1– 4 Jingsong He1,4 1Bone Marrow Transplantation Center, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, People’s Republic of China; 2Liangzhu Laboratory, Zhejiang University Medical Center, Hangzhou, Zhejiang Province, People’s Republic of China; 3Institute of Hematology, Zhejiang University, Hangzhou, Zhejiang Province, People’s Republic of China; 4Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy, Hangzhou, Zhejiang Province, People’s Republic of China; 5Department of Hematology and Cell Therapy, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: He Huang; Jingsong He, Bone Marrow Transplantation Center, the First Affiliated Hospital, Zhejiang University School of Medicine, No. 79 Qingchun Road, Hangzhou, Zhejiang Province, 310006, People’s Republic of China, Email huanghe@zju.edu.cn; hejingsong@zju.edu.cnPurpose: The growth and survival of multiple myeloma (MM) cells depend heavily on bone marrow microenvironment, where inflammation emerges as a significant feature and is commonly associated with unfavorable prognosis in MM. …”
Get full text

Prediction of Distant Metastasis of Renal Cell Carcinoma Based on Interpretable Machine Learning: A Multicenter Retrospective Study by Dong J, Duan M, Liu X, Li H, Zhang Y, Zhang T, Fu C, Yu J, Hu W, Peng S

“…Jinkai Dong,1,* Minjie Duan,2,3,* Xiaozhu Liu,4,* Huan Li,5 Yang Zhang,6 Tingting Zhang,7 Chengwei Fu,1 Jie Yu,8 Weike Hu,9 Shengxian Peng9,* 1Senior Department of Urology, the Third Medical Center of PLA General Hospital, Beijing, People’s Republic of China; 2Medical School of Chinese PLA, Beijing, People’s Republic of China; 3Medical Innovation Research Department, Chinese PLA General Hospital, Beijing, People’s Republic of China; 4Emergency and Critical Care Medical Center, Beijing Shijitan Hospital, Capital Medical University, Beijing, People’s Republic of China; 5Chongqing College of Electronic Engineering, Chongqing, People’s Republic of China; 6College of Medical Informatics, Chongqing Medical University, Chongqing, People’s Republic of China; 7Department of Endocrinology, Fifth Medical Center of Chinese PLA Hospital, Beijing, People’s Republic of China; 8Department of Medical Imaging, The Affiliated Taian City Central Hospital of Qingdao University, Taian, People’s Republic of China; 9Scientific Research Department, First People’s Hospital of Zigong City, Zigong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Shengxian Peng, Scientific Research Department, First People’s Hospital of Zigong City, No. 42, 1st Street, Shangyihao, ZiLiuJing District, ZiGong, SiChuan, 643000, People’s Republic of China, Email 13258280319@163.comBackground: : The traditional tool for predicting distant metastasis in renal cell carcinoma (RCC) is still insufficient. …”
Get full text

Remimazolam Suppresses Oxidative Stress and Apoptosis in Cerebral Ischemia/Reperfusion Injury by Regulating AKT/GSK-3β/NRF2 Pathway by Duan M, Yu N, Liu J, Zhao Y, Zhang J, Song S, Wang S

“…Mei Duan,1,* Ning Yu,1,* Jia Liu,1 Yang Zhao,1 Jing Zhang,1 Siyi Song,2 Shilei Wang1 1Department of Anesthesiology, The Affiliated Hospital of Qingdao University, Qingdao, People’s Republic of China; 2Department of Anesthesia and Perioperative Medicine, The First Affiliated Hospital of Shandong First Medical University, Jinan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Shilei Wang, Department of Anesthesiology, The Affiliated Hospital of Qingdao University, Qingdao, People’s Republic of China, Tel +86 186 6180 6773, Email wshlei@aliyun.comIntroduction: The mechanism of remimazolam, a benzodiazepine that activates γ-aminobutyric acid a (GABAa) receptors, in cerebral ischemia/reperfusion (I/R) injury is not well understood. …”
Get full text

High BMP7 Expression May Worsen Airway Disease in COPD by Altering Epithelial Cell Behavior by Dong W, Xie M, Ming C, Li H, Xu X, Cui L, Wang W, Li Y

“…Wenyan Dong,1,* Mengshuang Xie,2,* Chunjie Ming,3 Haijun Li,2 Xia Xu,2 Liwei Cui,4 Wei Wang,5 Yi Li6 1Department of General Practice, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, People’s Republic of China; 2Department of Geriatric Medicine, Laboratory of Gerontology and Anti-aging Research, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, People’s Republic of China; 3National Key Laboratory for Innovation and Transformation of Luobing Theory, The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, Department of Cardiology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, People’s Republic of China; 4Department of Pulmonary and Critical Care Medicine, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, People’s Republic of China; 5Medical Integration and Practice Center, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, People’s Republic of China; 6Department of Obstetrics and Gynecology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Wei Wang; Yi Li, Email styw28@163.com; 202062009073@email.sdu.edu.cnPurpose: Airway disease is the main pathological basis of chronic obstructive pulmonary disease (COPD), but the underlying mechanisms are unknown. …”
Get full text

A Multifunctional MIL-101-NH2(Fe) Nanoplatform for Synergistic Melanoma Therapy by Shang J, Chen Y, Wang F, Yang J, Li Y, Yang L, Liu X, Zhong Z, Yue C, Zhou M

“…Jinlu Shang,1,2,* Yongjun Chen,2,* Fangliang Wang,3,* Jing Yang,2 Yi Li,4 Liuxuan Yang,2 Xiuqiong Liu,1 Zhirong Zhong,5 Chaochi Yue,6 Meiling Zhou2 1Department of Pharmacy, West China Hospital Sichuan University Jintang Hospital, Chengdu, Sichuan, 610400, People’s Republic of China; 2Department of Pharmacy, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, 646000, People’s Republic of China; 3Chongqing Key Laboratory for Pharmaceutical Metabolism Research, Chongqing Pharmacodynamic Evaluation Engineering Technology Research Center, College of Pharmacy Chongqing Medical University, Chongqing, 400016, People’s Republic of China; 4Department of Nuclear Medicine, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, 646000, People’s Republic of China; 5Department of Pharmaceutical Sciences, School of Pharmacy, Southwest Medical University, Luzhou, Sichuan, 646000, People’s Republic of China; 6Department of Traditional Chinese Medicine, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, 646000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Meiling Zhou; Chaochi Yue, Email meilzhou@163.com; yuechaochi18@swmu.edu.cnBackground: Melanoma is an aggressive form of skin cancer, and single-modality treatments often fail to prevent tumor recurrence and metastasis. …”
Get full text

Integrating Bulk and Single-Cell Transcriptomic Data to Identify Ferroptosis-Associated Inflammatory Gene in Alzheimer’s Disease by Zhou H, Peng Y, Huo X, Li B, Liu H, Wang J, Zhang G

“…Huiqin Zhou,1– 3,* Yunjia Peng,2,3,* Xinhua Huo,2,3 Bingqing Li,2,3 Huasheng Liu,4 Jian Wang,3,5 Gaihua Zhang1 1College of Life Sciences, Hunan Normal University, Changsha, People’s Republic of China; 2Hunan Guangxiu Hospital, Hunan Normal University, Changsha, People’s Republic of China; 3National Engineering Center of Human Stem Cell, Changsha, People’s Republic of China; 4Department of Radiology, The Third Xiangya Hospital, Central South University, Changsha, People’s Republic of China; 5The Institute of Reproduction and Stem Cell Engineering, School of Basic Medical Sciences, Central South University, Changsha, People’s Republic of China*These authors contributed equally to this workCorrespondence: Gaihua Zhang, The National and Local Joint Engineering Laboratory of Animal Peptide Drug Development, College of Life Sciences, Hunan Normal University, Changsha, China. …”
Get full text

Il luogo e il senso: creazione e significazione degli spazi nel mondo globale by Gambardella, Fabiana, Amodio, Paolo

“…These are the sober word that Victor Hugo makes the priest pronounce when, at the down of modern age, he looked on with prophetic dismay at the advent of printing with movable type, a revolution that would completely transform not only the face and features of the human being, but even the stones, the physical and material space of signification, the dimension of belonging and the sacred, that an “emancipated humanity” would change with the use of reason, undermining every form of dogmatic authority and its symbol. If the ways human beings shaped the space around them indicate their evolution - the changes in their anthropological profile - then we wonder what form stones could take in an era when even the paper book is replaced by the changing words that appear on bright and seductive screens – the irreplaceable extensions of a super-emancipated species. …”
Get full text

The Diagnostic Value of Plasma NETs Levels and iCEB in Silent Myocardial Ischemia in Maintenance Hemodialysis Patients by Liu H, Han J, Ni W, Lu Y, Hu X, Wang J, Zhou Y, Wang Z, Cao J, Liu H

“…Haifei Liu,1,2,* Junling Han,3,* Weijie Ni,2 Yuan Lu,2 Xinhui Hu,2 Jing Wang,2 Yan Zhou,2 Ze Wang,4 Jingyuan Cao,1 Hong Liu2 1Department of Nephrology, The Affiliated Taizhou People’s Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, Jiangsu, 225300, People’s Republic of China; 2Institute of Nephrology, Zhongda Hospital, Southeast University School of Medicine, Nanjing, Jiangsu, 210009, People’s Republic of China; 3Clinical Laboratory, The Affiliated Taizhou People’s Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, Jiangsu, 225300, People’s Republic of China; 4Nanjing University of Chinese Medicine, Nanjing, Jiangsu, 210023, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hong Liu; Jingyuan Cao, Email jstzliu@sina.com; caojingyuan1989@163.comObjective: This study evaluated the diagnostic value of plasma Neutrophil extracellular traps (NETs) levels and the index of cardiac electrophysiological balance (iCEB) in identifying silent myocardial ischemia (SMI) in maintenance hemodialysis (MHD) patients.Methods: This cross-sectional observational study involved patients receiving MHD treatment. …”
Get full text

Experimental Investigation on Shear Strength between Ultra-High-Performance Concrete and Normal Concrete Substrates by Xinghong Jiang, Hengxiang Song, Ke Li, Jing Qiang, Jing Tian

Get full text