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33101
PCT/ALB Ratio in Initial Three days for the Prediction of Secondary Infection in Septic Patients
Published 2025-02-01“…Chunmei Zhang,1,* Guoge Huang,2,* Haizhong Li,1,3,* Tiancao Zhang,1 Mengling Jian,1 Chunyang Huang,1 Yingqin Zhang,1,4 Zheng Wang,5 Xun Hou,1 Yuanyuan Xia,6 Wenqiang Jiang1,7 1Emergency Intensive Care Unit, Department of Emergency Medicine, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong, People’s Republic of China; 2Department of Emergency Medicine, People’s Hospital of Longhua, Shenzhen, Guangdong, People’s Republic of China; 3Department of Emergency, Boai Hospital of Zhongshan, Zhongshan, Guangdong, People’s Republic of China; 4School of Medicine, South China University of Technology, Guangzhou University City, Guangzhou, Guangdong, People’s Republic of China; 5Guangdong Cardiovascular Institute, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, People’s Republic of China; 6Medical Oncology Department, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong, People’s Republic of China; 7Emergency Intensive Care Unit, Department of Emergency Medicine, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University; Guangdong Cardiovascular Institute, Guangdong Provincial People’s Hospital,Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Wenqiang Jiang; Yuanyuan Xia, Email jiangwenqiang@gdph.org.cn; xiayuany1021@163.comBackground: Procalcitonin (PCT) to albumin (ALB) ratio (PAR) in initial three days is a rapidly available indicator to assess the prognosis of patients with sepsis. …”
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33102
MetaboLINK is a novel algorithm for unveiling cell-specific metabolic pathways in longitudinal datasets
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33103
Playing hide and seek with primates: A comparative study of Theory of Mind
Published 2015-03-01“…Further analyses are in progress to identify predictive factors (e.g. familiarity with humans, age, motivation and frustration during the game) that could explain away inter-individual differences, thus eventually revealing (or not) inter‑species differences [Authors Aurore San‑Galli and Marie Devaine contributed equally to this work].…”
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33104
Paramedic Recognition of Sepsis in the Prehospital Setting: A Prospective Observational Study
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33105
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33106
Contezolid Harbored Equivalent Efficacy to Linezolid in Tuberculosis Treatment in a Prospective and Randomized Early Bactericidal Activity Study
Published 2025-01-01“…Guanglu Jiang,1,* Rongmei Liu,2,* Yi Xue,1 Qiping Ge,2 Lihui Nie,2 Zizheng Lv,2 Zhongshun Kong,2 Jin Shi,2 Hongmei Chen,2 Hua Li,2 Xiaoguang Wu,2 Li Xie,2 Yanhua Song,2 Hairong Huang,1 Mengqiu Gao2 1National Clinical Laboratory on Tuberculosis, Beijing Key Laboratory on Drug-Resistant Tuberculosis, Beijing Chest Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Department of Tuberculosis, Beijing Chest Hospital, Capital Medical University, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Mengqiu Gao; Hairong Huang, Email gaomqwdm@aliyun.com; huanghairong@tb123.orgBackground: Contezolid (CZD) is an analog of Linezolid (LZD) that has demonstrated potent in vitro and in vivo activity against tuberculosis (TB) while presenting a safer side-effect profile. …”
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33107
A Case Study Identified a New Mutation in the TTN Gene for Inherited Hypertrophic Cardiomyopathy
Published 2025-01-01“…Jiangtao Dong,1– 4,* Meilin Liu,1– 3,* Qianwen Chen,1– 3,5 Lingfeng Zha1– 3 1Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People’s Republic of China; 2Hubei Key Laboratory of Biological Targeted Therapy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People’s Republic of China; 3Hubei Provincial Engineering Research Center of Immunological Diagnosis and Therapy for Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People’s Republic of China; 4Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People’s Republic of China; 5Department of Pediatric Cardiology, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430070, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lingfeng Zha, Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, 430022, People’s Republic of China, Tel +86-15827177185, Email zhalf@hust.edu.cnBackground: Hypertrophic cardiomyopathy (HCM) is the most common hereditary cardiomyopathy, with variable pathogenesis, clinical presentation, and prognosis. …”
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33108
Noninvasive Detection of Alpha-Amylase in Saliva Using Screen-Printed Carbon Electrodes: A Promising Biomarker for Clinical Oral Diagnostics
Published 2025-01-01“…Faris Hernando Reviansyah,1,* Azzahra Delvyra Ristin,1,* Adil Abdul Rauf,2 Prisilia Dita Sepirasari,2 Fahmi Nur Alim,2 Yuspian Nur,3 Veni Takarini,4 Muhammad Yusuf,5 Dudi Aripin,6 Sri Susilawati,7 Maria Komariah,8 Boy Yoseph Cahya Sunan Sakti Syah Alam9 1Undergraduate Program, Faculty of Dentistry, Universitas Padjadjaran, Sumedang, 45363, Indonesia; 2Undergraduate Program, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Sumedang, 45363, Indonesia; 3Laboratory of Research and Development of FARMAKA TROPIS, Faculty of Pharmacy, Universitas Mulawarman, Samarinda, East Kalimantan, 75119, Indonesia; 4Department of Dental Materials and Technology, Faculty of Dentistry, Universitas Padjadjaran, Bandung, 40132, Indonesia; 5Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Sumedang, 45363, Indonesia; 6Department of Conservative Dentistry, Faculty of Dentistry, Universitas Padjadjaran, Bandung, 40132, Indonesia; 7Department of Dental Public Health, Faculty of Dentistry, Universitas Padjadjaran, Bandung, 40132, Indonesia; 8Department of Fundamental Nursing, Faculty of Nursing, Padjadjaran University, Bandung, 40132, Indonesia; 9Faculty of Geological Engineering, Universitas Padjadjaran, Jatinangor, Jawa Barat, 45363, Indonesia*These authors contributed equally to this workCorrespondence: Faris Hernando Reviansyah, Email faris21001@mail.unpad.ac.idBackground: Biomarkers are essential tools for diagnosing diseases. …”
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33109
The Association of Inflammatory Indexes Derived from Peripheral Blood Cell Count and Clinical Signs with Response to Treatment with Dupilumab in Pediatric Patients with Moderate-to...
Published 2025-01-01“…Lingzhao Zhang,1,2 Jiangshan Pi,1,2 Jinsong Wang,3 Jingsi Chen,1 Yunxuan Zhang,1,2 Jie Li,4 Lingling Wang,1,2 Yue Li,1,2 Anwei Chen,1 Xiaoyan Luo,1,5,* Hua Wang1,2,5,* 1Department of Dermatology, Children’s Hospital of Chongqing Medical University, Chongqing, People’s Republic of China; 2Chongqing Key Laboratory of Child Infection and Immunity, Children’s Hospital of Chongqing Medical University, Chongqing, People’s Republic of China; 3Department of Gastroenterology, Chongqing Dongnan Hospital, Chongqing, People’s Republic of China; 4Department of Pediatrics, Chongqing Jiangjin District Maternal and Child Health Hospital, Chongqing, People’s Republic of China; 5Ministry of Education Key Laboratory of Child Development and Disorders, Children’s Hospital of Chongqing Medical University, Chongqing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hua Wang; Xiaoyan Luo, Department of Dermatology, Children’s Hospital of Chongqing Medical University, No. 136 Zhongshan Second Road, Yuzhong District, Chongqing, 400015, People’s Republic of China, Tel +8615123380348, Email huawang@hospital.cqmu.edu.cn; xyluo@hospital.cqmu.edu.cnBackground: Dupilumab is a safe and effective treatment for moderate to severe atopic dermatitis (AD), but real-world data in pediatric patients in China are limited. …”
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33110
USC-Derived Small Extracellular Vesicles-Functionalized Scaffolds Promote Scarless Vaginal Defect Repair via Delivery of Decorin and DUSP3 Proteins
Published 2025-02-01“…Yiyun Xu,1,* Jie Li,1,* Yu Qiu,1 Fuyue Wu,2 Zhuowei Xue,1 Bin Liu,1 Hongjie Fan,1 Yuedi Zhou,1 Qingkai Wu1 1Department of Obstetrics and Gynecology, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, People’s Republic of China; 2Organoid Regeneration Research Center, ReMed Regenerative Medicine Clinical Application Institute, Shanghai, 201114, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qingkai Wu; Yuedi Zhou, Email wuqingkai@sjtu.edu.cn; zhouyuedi@126.comBackground: Scar formation following large-area vaginal defects post-vaginoplasty is a major clinical challenge. …”
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33111
Clinical Utility of the Trajectory of Serum Bilirubin and International Normalized Ratio Values in Hepatitis B Virus-Related Acute-on-Chronic Liver Failure
Published 2025-02-01“…Ya-qi Song,1,2,* Xin-yu Fu,1,3,* Si-yan Yan,4 Rong-bin Qi,5 Yi-jing Zhou,1 Jia-wei Liang,6 Jin-qiu Zhang,1 Li-ping Ye,1 Xin-li Mao,1 Shao-wei Li1 1Department of Gastroenterology, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, Zhejiang, People’s Republic of China; 2Department of Gastroenterology, Taizhou Hospital of Zhejiang Province, Linhai, Zhejiang, People’s Republic of China; 3Dalian Medical University, Dalian, People’s Republic of China; 4Department of Gastroenterology, Taizhou Hospital of Zhejiang Province, Zhejiang University, Linhai, Zhejiang, People’s Republic of China; 5Department of Respiratory Medicine, TaiZhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, Zhejiang, People’s Republic of China; 6Department of Thoracic Surgery, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xin-li Mao; Shao-wei Li, Department of Gastroenterology, Taizhou Hospital of Zhejiang Province affiliated With Wenzhou Medical University, Linhai, Zhejiang Province, People’s Republic of China, Email maoxl@enzemed.com; li_shaowei81@hotmail.comBackground and Aim: Acute-on-chronic liver failure (ACLF) is a rapidly progressive and highly fatal condition. …”
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33112
Prognostic Value of Inflammatory and Nutritional Indicators in Non-Metastatic Soft Tissue Sarcomas
Published 2025-02-01“…Yuan Yan,1– 3,* Yunhui Zhang,1– 3,* Yonghan Chen,1– 3,* Guoqing Zhong,2,3 Wenhan Huang,2,3 Yu Zhang1– 3 1School of Medicine, South China University of Technology, Guangzhou, Guangdong, People’s Republic of China; 2Department of Orthopaedics Oncology, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong, People’s Republic of China; 3School of Materials Science and Engineering (National Engineering Research Center for Tissue Restoration and Reconstruction), South China University of Technology, Guangzhou, Guangdong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yu Zhang; Wenhan Huang, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Zhongshan 2nd Road, Guangzhou, Guangdong, People’s Republic of China, Email luck_2001@126.com; wenhanx@126.comBackground: Soft tissue sarcoma (STS) has lacked reliable prognostic indicators. …”
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33113
Diagnostic Value of Glycosylated Extracellular Vesicle microRNAs in Gastric Cancer
Published 2025-01-01“…., Ltd, Beijing, 102600, People’s Republic of China; 5Department of Endoscopy, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, People’s Republic of China*These authors contributed equally to this workCorrespondence: Shun He, Department of Endoscopy, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, People’s Republic of China, Email heshuns@126.com Jianwei Zhang, Department of Pancreatic and Gastric Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, People’s Republic of China, Email panchutong@163.comIntroduction: Early diagnosis is crucial for improving the prognosis of patients with gastric cancer (GC). …”
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33114
Neuroprotective Effects of Eugenol Acetate Against Ischemic Stroke
Published 2025-01-01“…Liqiu Chen,1,2,* Ran Zhang,1,2,* Jing Xiao,1,2,* Ying Liang,1,2 Zhen Lan,3 Yingao Fan,2 Xi Yu,2 Shengnan Xia,2– 5 Haiyan Yang,2– 5 Xinyu Bao,2– 5 Hailan Meng,1– 6 Yun Xu,1– 6 Linjie Yu,1– 6 Xiaolei Zhu1– 6 1Department of Neurology, Nanjing Drum Tower Hospital, Clinical College of Nanjing University of Chinese Medicine, Nanjing, 210008, People’s Republic of China; 2Department of Neurology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210008, People’s Republic of China; 3Department of Neurology, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing, 210008, People’s Republic of China; 4State Key Laboratory of Pharmaceutical Biotechnology and Institute of Translational Medicine for Brain Critical Diseases, Nanjing University, Nanjing, 210008, People’s Republic of China; 5Jiangsu Provincial Key Discipline of Neurology, Nanjing, 210008, People’s Republic of China; 6Nanjing Neurology Medical Center, Nanjing, 210008, People’s Republic of China*These authors contributed equally to this workCorrespondence: Linjie Yu; Xiaolei Zhu, Department of Neurology, Nanjing Drum Tower Hospital, Clinical College of Nanjing University of Chinese Medicine, Nanjing, 210008, People’s Republic of China, Email yulinjie126@126.com; zhuquelee@126.comObjective: To explore the neuroprotective effect of Eugenol Acetate (EA) on post-stroke neuroinflammation and investigate the underlying mechanisms.Methods: For in vitro experiments, primary microglia were pre-incubated with EA for 2 hours, followed by lipopolysaccharide (LPS) stimulation for 24 hours or Oxygen-Glucose Deprivation (OGD) treatment for 4 hours. …”
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33115
Deciphering Immunometabolic Landscape in Rheumatoid Arthritis: Integrative Multiomics, Explainable Machine Learning and Experimental Validation
Published 2025-01-01“…Qiu Dong,1,* Jiayang Wu,2,3,* Huaguo Zhang,4,* Xinhui Chen,2,3 Xi Xu,2,3 Jifeng Chen,3 Changzheng Shi,2,3,5 Liangping Luo,3,5 Dong Zhang2,3 1Department of Bone and Joint Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, People’s Republic of China; 2Medical Imaging Centre, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, People’s Republic of China; 3The Guangzhou Key Laboratory of Molecular and Functional Imaging for Clinical Translation, the First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, People’s Republic of China; 4Department of Ultrasonography, the First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, People’s Republic of China; 5Medical Imaging Centre, the Fifth Affiliated Hospital of Jinan University, Heyuan, Guangdong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Dong Zhang, Email lbzhangdong@126.comPurpose: Immunometabolism is pivotal in rheumatoid arthritis (RA) pathogenesis, yet the intricacies of its pathological regulatory mechanisms remain poorly understood. …”
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33116
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33117
Impact of Antimicrobial Stewardship and Infection Prevention and Control Programmes on Antibiotic Usage and A. baumannii resistance: A 2016–2023 Multicentre Prospective Study
Published 2025-02-01“…Lei Liu,1,2,* Bin Liu,1,2,* Liang Li,1,2 Yu Li,3 Xiangdong Zhou,1,2 Qi Li1,2 1Department of Respiratory Medicine, The First Affiliated Hospital, Hainan Medical University, Haikou, Hainan, People’s Republic of China; 2Hainan Province Clinical Medical Center of Respiratory Disease, Haikou, Hainan, People’s Republic of China; 3Department of Respiratory Medicine, The Fourth Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qi Li, Email lqlq198210@sina.comObjective: This study assesses the efficacy of antimicrobial stewardship (AMS) and infection prevention and control programmes (IPCP) in guiding the use of antibiotics and the control of A. baumannii (AB) resistance at multiple medical centres.Methods: We evaluated the effectiveness of the policy on antibiotic consumption and AB resistance by determining the relationship between the defined daily doses (DDD) for antibiotics – or alcohol-based hand gel (ABHG) consumption – and the incidence of carbapenem-resistant AB (CR-AB), multidrug-resistant AB (MDR-AB) and extensively drug-resistant AB (XDR-AB) at two medical centers from 2016– 2023.Results: In total, 4057 AB isolates were collected; 64.95% of the AB isolates were CR, 59.48% were MDR and 1.41% were XDR. …”
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33118
Assessing Sedation Depth with PSI in Elderly ERCP Patients: A Prospective Cohort Study
Published 2025-02-01“…Lei Huang,1,2,* Lin-lin Liu,1,2,* Yong-da Lu,3,* Min-yuan Zhuang,1,2 Wei Dou,1,2 Hong Liu,4 Fu-hai Ji,1,2 Ke Peng1 1Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, People’s Republic of China; 2Institute of Anesthesiology, Soochow University, Suzhou, Jiangsu, People’s Republic of China; 3Department of Gastroenterology, First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, People’s Republic of China; 4Department of Anesthesiology and Pain Medicine, University of California Davis Health, Sacramento, CA, USA*These authors contributed equally to this workCorrespondence: Ke Peng, Department of Anesthesiology, First Affiliated Hospital of Soochow University, 188 Shizi Street, Suzhou, Jiangsu, 215006, People’s Republic of China, Tel +86-512-67780056 ; +86-15962155989, Email pengke0422@163.comBackground: Adequate sedation is important for elderly patients undergoing endoscopic retrograde cholangiopancreatography (ERCP). …”
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33119
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33120
Stress and Interpersonal Relationships in Medical Students During Public Health Emergencies: A Network Analysis
Published 2025-01-01“…Yi Cui,1,* Zhihua Guo,2,* Tianqi Yang,2,3,* Man Zhang,4 Hezi Mu,5 Jiayao Li,1 Jiaxin Fang,6 Tianshu Du,1,2 Xiaomei Yang7 1Department of Nursing, Air Force Medical University, Xi’an, People’s Republic of China; 2Department of Military Medical Psychology, Air Force Medical University, Xi’an, People’s Republic of China; 3 93575 Unit of the Chinese People’s Liberation Army, Chengde, People’s Republic of China; 4Department of Nursing, Shaanxi Provincial People’s Hospital, Xi’an, People’s Republic of China; 5Department of Orthopedics, The Second Affiliated Hospital of Air Force Medical University, Xi’an, People’s Republic of China; 6Department of Nursing, Beijing University of Chinese Medicine, Beijing, People’s Republic of China; 7Department of Gynecology, Shaanxi Provincial People’s Hospital, Xi’an, People’s Republic of China*These authors contributed equally to this workCorrespondence: Tianshu Du, Department of Nursing, Air Force Medical University, Xi’an, 710000, People’s Republic of China, Email dutianshu1985@163.com Xiaomei Yang, Department of Gynecology, Shaanxi Provincial People’s Hospital, Xi’an, 710000, People’s Republic of China, Email XiaoMeiYang2081@outlook.comBackground: With the growing demand for medical services worldwide, especially during public health emergencies, medical students, as a special group of future medical workers, are important for the development of health services, and they therefore experience more stress than ordinary college students do. …”
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