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32821
Increased Co-Expression of PD-L1 and CTLA-4 Predicts Poor Overall Survival in Patients with Acute Myeloid Leukemia Following Allogeneic Hematopoietic Stem Cell Transplantation
Published 2025-01-01“…Cunte Chen,1,2,* Kangjie Qiu,2,* Jie Chen,3,* Shunqing Wang,1 Yuping Zhang,1 Caixia Wang,1 Yangqiu Li2 1Department of Hematology, Guangzhou First People’s Hospital, Institute of Blood Transfusion and Hematology, Guangzhou Medical University, Guangzhou, 510180, People’s Republic of China; 2Institute of Hematology, School of Medicine, Key Laboratory for Regenerative Medicine of Ministry of Education, Jinan University, Guangzhou, People’s Republic of China; 3Department of Hematology, First Affiliated Hospital, Jinan University, Guangzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yangqiu Li, Institute of Hematology, School of Medicine, Key Laboratory for Regenerative Medicine of Ministry of Education, Jinan University, Guangzhou, 510632, People’s Republic of China, Email yangqiuli@hotmail.com Caixia Wang, Department of Hematology, Guangzhou First People’s Hospital, Institute of Blood Transfusion and Hematology, Guangzhou Medical University, Guangzhou, 510180, People’s Republic of China, Email wangcx225@163.comPurpose: Our previous study has demonstrated that high expression of immune checkpoints (ICs) was significantly associated with adverse clinical outcomes in patients with acute myeloid leukemia (AML). …”
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32822
Measuring. Monitoring. Management. Control
Published 2024-12-01“…To solve this problem, the authors propose the combination and integration of non-precision measurements, which, in turn, requires determining the threshold values of measurement errors. …”
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32823
Motor transport development in Klaipėda district in 1900-1939
Published 2009-12-01“…Based on decrees of the district's authority, people were punished for violation of traffic rules (exceeding the speed limit, driving drunk, using a car without permission extended, etc.), and the most frequent penalty applied was monetary fines. …”
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32824
Impact of Herpesvirus Detection via Metagenomic Next-Generation Sequencing in Patients with Lower Respiratory Tract Infections
Published 2025-01-01“…., Ltd, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Wei Gai, WillingMed Technology (Beijing) Co., Ltd, No. 156 Jinghai 4th Road, Beijing Economic and Technological Development Zone, Beijing, 101103, People’s Republic of China, Email weigai@willingmed.com Huaying Wang, The Affiliated People’s Hospital of Ningbo University, Yinzhou People’s Hospital, No. 251, Baizhang East Road, Ningbo, 315040, People’s Republic of China, Email yingmeire@163.comPurpose: This study aimed to investigate the impact of herpesvirus detection by metagenomic next-generation sequencing (mNGS) of bronchoalveolar lavage fluid (BALF) on lower respiratory tract infections (LRTIs) patients’ lung microbiome composition and prognosis.Patients and methods: We initially enrolled 234 hospitalized patients with LRTIs who underwent BALF mNGS between February 2022 and May 2023. …”
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32825
How Does Indonesian Chronic Disease Patient Adhere to Their Treatment? A Cross-Sectional Analysis of 11,408 Subjects
Published 2025-01-01“…Ivan Surya Pradipta,1,2,* Kevin Aprilio,1,2,* Yozi Fiedya Ningsih,1,2 Mochammad Andhika Aji Pratama,2 Vesara Ardhe Gatera,3 Sofa Dewi Alfian,1,2 Aulia Iskandarsyah,4 Rizky Abdulah1,2 1Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, West Java, 45363, Indonesia; 2Drug Utilization and Pharmacoepidemiology Research Group, Center of Excellence in Higher Education for Pharmaceutical Care Innovation, Universitas Padjadjaran, Sumedang, West Java, 45363, Indonesia; 3Department of Pharmaceutical Biology, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, West Java, 45363, Indonesia; 4Department of Clinical Psychology, Faculty of Psychology, Universitas Padjadjaran, Sumedang, West Java, 45363, Indonesia*These authors contributed equally to this workCorrespondence: Ivan Surya Pradipta, Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Jalan Ir. …”
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32826
LBP-CD155 Liposome Nanovaccine Efficiently Resist Colorectal Cancer and Enhance ICB Therapy
Published 2025-01-01“…Yajuan Yan,1,* Ting Duan,1,* Xiaonan Xue,1,* Xiaojuan Yang,2 Miao Liu,2 Bin Ma,3,4 Xiangguo Duan,2 Chunxia Su1 1Department of Basic Medicine, Ningxia Medical University, Yinchuan, Ningxia, People’s Republic of China; 2Department of Inspection, Ningxia Medical University, Yinchuan, Ningxia, People’s Republic of China; 3Department of Surgery, The First People’s Hospital of Yinchuan, Yinchuan, Ningxia, People’s Republic of China; 4The Second School of Clinical Medicine, Ningxia Medical University, Yinchuan, 750004, People’s Republic of China*These authors contributed equally to this workCorrespondence: Chunxia Su; Xiangguo Duan, Email chunxiasu@qq.com; duanxiangguo@nxmu.edu.cnBackground: Colorectal cancer (CRC) is a highly malignant and aggressive gastrointestinal tumor. …”
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32827
Giant Granular Cell Tumor of the Left Thigh, a Rare Case Report and Literature Review
Published 2025-01-01“…Qian Liu,1,* Xiangyu Kong,2,* Jun Yang,3 Dongdong Zhang1 1Department of Oncology, Xiangyang No. 1 People’s Hospital, Hubei University of Medicine, Xiangyang, 441000, People’s Republic of China; 2Department of Radiology, Xiangyang No. 1 People’s Hospital, Hubei University of Medicine, Xiangyang, 441000, People’s Republic of China; 3Department of Neurology, Xiangyang No. 1 People’s Hospital, Hubei University of Medicine, Xiangyang, 441000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jun Yang, Department of Neurology, Xiangyang No. 1 People’s Hospital, Hubei University of Medicine, Xiangyang, 441000, People’s Republic of China, Email 296051103@qq.com Dongdong Zhang, Department of Oncology, Xiangyang No. 1 People’s Hospital, Hubei University of Medicine, Jiefang Road No. 15, Xiangyang, Hubei, 441000, People’s Republic of China, Tel +8615072278600, Email zhangdongdong@whu.edu.cnBackground: Granular cell tumor (GCT) is a rare soft tissue tumor characterized by Schwann cell differentiation. …”
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32828
Deciphering the Role of CD36 in Gestational Diabetes Mellitus: Linking Fatty Acid Metabolism and Inflammation in Disease Pathogenesis
Published 2025-02-01“…Li Huang,1– 3,* Tong Zhang,4,* Yuanyuan Zhu,5 Xueling Lai,6 Hualin Tao,1– 3 Yuhan Xing,5 Zhaoyinqian Li1– 3 1Department of Laboratory Medicine, the Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, People’s Republic of China; 2Sichuan Province Engineering Technology Research Center of Molecular Diagnosis of Clinical Diseases, Luzhou, Sichuan, People’s Republic of China; 3Molecular Diagnosis of Clinical Diseases Key Laboratory of Luzhou, Luzhou, Sichuan, People’s Republic of China; 4Department of Laboratory Medicine, Southwest Medical University, Luzhou, Sichuan, People’s Republic of China; 5School of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen, Guangdong, People’s Republic of China; 6Shenzhen Guangming Maternal & Child Healthcare Hospital, Shenzhen, Guangdong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhaoyinqian Li, Department of Laboratory Medicine, The Affiliated Hospital of Southwest Medical University, No. 25, Taiping Street, Jiangyang District, Luzhou, Sichuan, 646000, People’s Republic of China, Email lizhaoyinqian@swmu.edu.cn Yuhan Xing, School of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen, 518107, People’s Republic of China, Email xingyh8@mail.sysu.edu.cnAbstract: Gestational diabetes mellitus (GDM) is one of the most common pregnancy complications which exerts detrimental effects on mothers and children. …”
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32829
Unveiling the Effect of Age and IgE Level on Alopecia Areata: Insights from Comparative RNAseq Analysis
Published 2025-01-01“…Huiting Liu,* Sai Yang,* Hua Xian, Yinghui Liu, Yan Zhang, Yangxia Chen, Yingping Xu, Jun Liu, Bin Yang, Ying Luo Department of Dermatology, Dermatology Hospital, Southern Medical University, Guangzhou, 510091, People’s Republic of China*These authors contributed equally to this workCorrespondence: Bin Yang; Ying Luo, Department of Dermatology, Dermatology Hospital, Southern Medical University, No. 2 Lujing Road, Yuexiu District, Guangzhou, People’s Republic of China, Email yangbin1@smu.edu.cn; luoyingmab@yahoo.comBackground: Alopecia areata (AA) is a common autoimmune disease, causes sudden hair loss on the scalp, face, and sometimes other areas of the body. …”
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32830
UPLC-ESI-MS/MS Profile and Antioxidant, Cytotoxic, Antidiabetic, and Antiobesity Activities of the Aqueous Extracts of Three Different Hibiscus Species
Published 2020-01-01“…The aqueous extracts of Hibiscus calyphyllus (HcA), Hibiscus micranthus (HmA), and Hibiscus deflersii (HdA) growing in Saudi Arabia did not receive enough attention in phytochemical and biological studies. This inspired the authors to investigate the phytochemicals of these extracts for the first time using UPLC-ESI-MS/MS in negative and positive ionization modes. …”
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32831
Making Maoshan Great Again: Religious Rhetoric and Popular Mobilisation from Late Qing to Republican China (1864–1937)
Published 2025-01-01“…Through a detailed analysis of primary sources, including editions of the <i>Maoshan Gazetteer</i>, liturgical manuals such as the scripture (<i>jing</i> 經), litany (<i>chan</i> 懺), and performative texts such as the precious scroll (<i>baojuan</i> 寶卷) of the Three Mao Lords, this study identifies six key rhetoric strategies employed by Maoshan Daoists, using the acronym IMPACT: (1) Incorporation: Appending miracle tales (<i>lingyan ji</i> 靈驗記) and divine medicine (<i>xianfang</i> 仙方) to address immediate and practical needs of contemporary society; (2) Memory: Preserving doctrinal continuity while invoking cultural nostalgia to reinforce connections to traditional values and heritage; (3) Performance: Collaborating with professional storytellers to disseminate vernacularized texts through oral performances, thereby reaching broader audiences including the illiterate. (4) Abridgment: Condensing lengthy texts into concise and accessible formats; (5) Canonization: Elevating the divine status of deities through spirit-writing, thereby enhancing their religious authority; (6) Translation: Rendering classical texts into vernacular language for broader accessibility. …”
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32832
Interleukin-6 as a Pan-Cancer Prognostic Inflammatory Biomarker: A Population-Based Study and Comprehensive Bioinformatics Analysis
Published 2025-01-01“…Hailun Xie,1,* Lishuang Wei,1,* Guotian Ruan,2– 5 Heyang Zhang,2– 5 Hanping Shi1 1Department of Gastrointestinal and Gland Surgery, the First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi, People’s Republic of China; 2Department of Gastrointestinal Surgery, Department of Clinical Nutrition, Beijing Shijitan Hospital, Capital Medical University, Beijing, People’s Republic of China; 3National Clinical Research Center for Geriatric Diseases, Xuanwu Hospital, Capital Medical University, Beijing, People’s Republic of China; 4Key Laboratory of Cancer FSMP for State Market Regulation, Beijing, People’s Republic of China; 5Laboratory for Clinical Medicine, Capital Medical University, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hanping Shi, Department of Gastrointestinal and Gland Surgery, the First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi, People’s Republic of China, Email shihp@ccmu.edu.cnPurpose: Interleukin-6 (IL-6) is a central factor linking inflammation to cancer. …”
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32833
Health and school difficulties of children in foster care in the experience of their foster parents
Published 2024-06-01“…The study was implemented as part of a dissertation at the University of South Bohemia in České Budějovice in the Czech Republic on the topic of promotion of the health, social and psychological well-being of school-aged children in the context of their school and family environment. The authors carried out a questionnaire survey in the Czech Republic among a selected sample of respondents, who were foster parents of children aged 6 to 15 attending primary school in the Pardubice Region. …”
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32834
Network Pharmacology Combined With Metabolomics Reveals the Mechanism of Yangxuerongjin Pill Against Type 2 Diabetic Peripheral Neuropathy in Rats
Published 2025-01-01“…Pharmaceutical Factory, Beijing, 100079, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yi Xu; Jinsheng Li, Beijing Tongrentang Technology Development Co., Ltd. …”
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32835
CECT-Based Radiomic Nomogram of Different Machine Learning Models for Differentiating Malignant and Benign Solid-Containing Renal Masses
Published 2025-01-01“…Lu Qian,1,* BinHai Fu,2,* Hong He,2 Shan Liu,1 RenCai Lu2 1Department of Pathology, the First People’s Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, 650032, People’s Republic of China; 2Department of Nuclear Medicine, The First People’s Hospital of Yunnan Province, the Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, 650032, People’s Republic of China*These authors contributed equally to this workCorrespondence: RenCai Lu, Department of Nuclear Medicine, The First People’s Hospital of Yunnan Province, the Affiliated Hospital of Kunming University of Science and Technology, No. 157 Jinbi Road, Kunming, Yunnan, 650032, People’s Republic of China, Tel +86 087163614503, Email lrc_09@126.comObjective: This study aimed to explore the value of a radiomic nomogram based on contrast-enhanced computed tomography (CECT) for differentiating benign and malignant solid-containing renal masses.Materials and Methods: A total of 122 patients with pathologically confirmed benign (n=47) or malignant (n=75) solid-containing renal masses were enrolled in this study. …”
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32836
Genetic and Plasma Proteomic Approaches to Identify Therapeutic Targets for Graves’ Disease and Graves’ Ophthalmopathy
Published 2025-02-01“…Chenxin Ke,1,* Yuefeng Yu,1,* Jiang Li,1 Yuetian Yu,1 Ying Sun,1 Yuying Wang,1 Bin Wang,1 Yingli Lu,1 Mengjun Tang,2 Ningjian Wang,1 Yi Chen1 1Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, People’s Republic of China; 2Orthopedic Department, Taizhou Hospital of Zhejiang Province, Zhejiang University, Taizhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yi Chen, Email chenyi9h@126.com; Ningjian Wang, Email wnj486@126.comBackground: The blood proteome is a major source of biomarkers and therapeutic targets. …”
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32837
Fully Covered Stent-TIPS for Advanced HCC Patients with Portal Vein Tumor Thrombus-Related Severe Symptomatic Portal Hypertension
Published 2025-01-01“…Zechuan Liu,1,* Tianshi Lyu,1,* Jinming Yang,2 Yong Xie,1 Siyuan Fan,1 Li Song,1 Yinghua Zou,1 Jian Wang1 1Department of Interventional and Vascular Surgery, Peking University First Hospital, Beijing, People’s Republic of China; 2Department of Vascular Interventional, Aerospace Central Hospital, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jian Wang; Yinghua Zou, Department of Interventional and Vascular Surgery, Peking University First Hospital, Beijing, People’s Republic of China, Email wangjianbdyy@126.com; Dr_zouyinghua@126.comPurpose: Portal vein tumor thrombus (PVTT)–related severe symptomatic portal hypertension (SPH) leads to a poor prognosis in patients with advanced hepatocellular carcinoma (HCC). …”
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32838
The Combination of D-TACE-HAIC, Lenvatinib, and PD-1 Inhibitors Shows Significant Clinical Efficacy in Patients with Unresectable Hepatocellular Carcinoma
Published 2025-02-01“…Yintao Wu,* Jianyong Zhu,* Hong Zhang, Nianxin Xia Senior Department of Hepato-Pancreato-Biliary Surgery, the First Medical Center of PLA General Hospital, Beijing, 100853, People’s Republic of China*These authors contributed equally to this workCorrespondence: Nianxin Xia, Senior Department of Hepato-Pancreato-Biliary Surgery, the First Medical Center of PLA General Hospital, Beijing, 100853, People’s Republic of China, Email doctorxnx@163.comPurpose: This study was developed to compare the efficacy of combined D-TACE-HAIC + lenvatinib + PD-1 inhibitor treatment to that of TACE + sorafenib treatment for patients with intermediate and advanced HCC.Patients and Methods: Here, a retrospective analysis of patients with unresectable HCC who underwent transarterial chemoembolization (TACE) from March 2018 to March 2022 at the our hospital was conducted. …”
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32839
Statistical match reports of the 2022 volleyball World Championship in the context of network analysis with Gephi
Published 2023-12-01“…The HITS (Hyperlink-Induced Topic Search) metric assesses the node significance in the graph in terms of hubs and authorities. High HITS values pinpoint pivotal players acting as hubs, signifying their numerous connections with fellow teammates. …”
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32840
Tumor-Stroma Ratio is a Critical Indicator of Peritoneal Metastasis in Gastric Cancer
Published 2025-01-01“…Lin Zhong,1,* Hongyun Huang,2,* Dong Hou,1,* Shihai Zhou,3 Yu Lin,4 Yue Yu,4 Jinhao Yu,1 Fanghai Han,5 Lang Xie6 1Department of Gastrointestinal Surgery, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, 510120, People’s Republic of China; 2Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100010, People’s Republic of China; 3Department of Tumor Surgery, Zhongshan City People’s Hospital, Zhongshan, Guangdong, 528403, People’s Republic of China; 4Department of Pathology, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, 510282, People’s Republic of China; 5Department of Gastrointestinal Surgery, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong, 5181025, People’s Republic of China; 6Department of General surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, 510282, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lang Xie; Fanghai Han, Email langxiezj@hotmail.com; fh_han@163.comObjective: This study aims to investigate the correlation between the tumor-stroma ratio (TSR) and peritoneal metastasis (PM) in gastric cancer (GC) and constructs a diagnostic model based on preoperative examination data.Methods: To determine the feasibility of obtaining TSR in GC patients through preoperative examinations, the consistency of TSR between endoscopic biopsy tissues and postoperative histopathological tissues was evaluated. …”
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