Microiontophoretic Application of Dynorphin in Dental Pain: Excitatory or Inhibitory Effects by Choi SH, Kim YM, Son JY, Ahn DK

“…Seung-Ho Choi,* Yu-Mi Kim,* Jo-Young Son, Dong-Kuk Ahn Department of Oral Physiology, School of Dentistry, Kyungpook National University, Daegu, Korea*These authors contributed equally to this workCorrespondence: Dong-Kuk Ahn, Department of Oral Physiology, School of Dentistry, Kyungpook National University, 2177, Dalgubeol-Daero, Jung-Gu, Daegu, 41940, Korea, Tel +82-53-660-6840, Email dkahn@knu.ac.krBackground: The tooth exhibits increased sensitivity to noxious stimuli due to the dense innervation of thin myelinated Aδ fibers and unmyelinated C fibers within the dental pulp. …”
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Developing a business model focused on the planning sustainability of forest sector enterprises by Ihor Soloviy, Orest Kiyko, Vasyl Lavnyy, Igor Bukhanevych, Oksana Pelyukh, Mykhailo Ilkiv, Taras Chelepis, Dmytro Savka, Andriy Lutsenco

“…The article analyzes the main countries, journals, leading authors and main disciplinary areas in which articles on sustainable business models are published. …”
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Exploring the Causal Relationship and Molecular Mechanisms Between Fasting Insulin and Androgenetic Alopecia: A Mendelian Randomization Study with Bioinformatics Analysis by Ding X, Bai Z, Wang W, Gu Y, Li Z, Fan Y

“…Xiaoxia Ding,1,* Zicheng Bai,2,* Wenwen Wang,2 Yu Gu,3 Zhiming Li,2 Yibin Fan1 1Center for Plastic & Reconstructive Surgery, Department of Dermatology, Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, People’s Republic of China; 2Department of Dermatology and Venereology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China; 3Department of Dermatology, The First People’s Hospital of Aksu Prefecture, Aksu, XinJiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yibin Fan, Email fanyibin@hmc.edu.cn; Zhiming Li, Email zhi-mingli@wmu.edu.comBackground: Prior studies have suggested a significant connection between fasting insulin (FI) and androgenetic alopecia (AGA), but the exact cause of this connection and underlying molecular mechanism has not been clarified. …”
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Treatment of Severe Hypercapnic Respiratory Failure Caused by SARS-CoV-2 Lung Injury with ECCO2R Using the Hemolung Respiratory Assist System by Ramiro Saavedra-Romero, Francisco Paz, John M. Litell, Julia Weinkauf, Carina C. Benson, Lisa Tindell, Kari Williams

“…She met the criteria for treatment with an investigational ECCO2R device (Hemolung Respiratory Assist System) available through FDA Emergency Use Authorization. ECCO2R is similar to extracorporeal membrane oxygenation (ECMO) but operates at much lower blood flows (350–550 mL/min) through a smaller 15.5 French central venous catheter. …”
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The Association Between Insomnia and Temporomandibular Disorders in Orthodontic Patients by Dong Y, Zhou X, Xiang J, Zheng Y, Zheng Y, Xiong X, Wang J

“…Yanhua Dong,* Xueman Zhou,* Jie Xiang, Yunhao Zheng, Yingcheng Zheng, Xin Xiong, Jun Wang State Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xin Xiong; Jun Wang, West China Hospital of Stomatology, Sichuan University, No. 14 section 3, Renmin South Road, Chengdu, 610041, People’s Republic of China, Email drxiongxin@scu.edu.cn; wangjunv@scu.edu.cnObjective: This cross-sectional study aimed to investigate the association between insomnia and the presence of temporomandibular disorders (TMD) and its subtypes in orthodontic patients.Methods: A total of 648 adult orthodontic patients (158 males and 490 females, median age 26) were included and completed a questionnaire containing sociodemographic information, insomnia severity index (ISI), the five major temporomandibular disorder symptoms (5Ts) checklist, and self-reported sleep bruxism. …”
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Participant Contributions to Person-Generated Health Data Research Using Mobile Devices: Scoping Review by Shanshan Song, Micaela Ashton, Rebecca Hahn Yoo, Zoljargal Lkhagvajav, Robert Wright, Debra J H Mathews, Casey Overby Taylor

“…We observed a rapid increase in all publications from 2016 to 2021, with the largest contribution from US authors, with 1 exception, review articles. Few original research publications used crowdsourcing platforms (7%, 3/45). …”
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Comprehensive Analysis of Metabolic Changes in Mice Exposed to Corilagin Based on GC-MS Analysis by Xu B, Wang C, Zhu X, Zhu L, Han G, Cui C

“…Biao Xu,1,* Changshui Wang,2,* Xiaodong Zhu,2 Li Zhu,3 Guangkui Han,2 Changmeng Cui2 1Clinical Medical School, Jining Medical University, Jining, 272067, People’s Republic of China; 2Department of Neurosurgery, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, 272000, People’s Republic of China; 3Translational Pharmaceutical Laboratory, Jining No. 1 People’s Hospital, Shandong First Medical University, Jining, 272000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Changmeng Cui; Guangkui Han, Department of Neurosurgery, Affiliated Hospital of Jining Medical University, 89 Guhuai Road, Jining, Shandong, 272000, People’s Republic of China, Tel +86 0537 2908518, Email cmcuidr1989@163.com; guangkui_han@163.comBackground: Corilagin is widely distributed in various medicinal plants. …”
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Peculiarities of the clinical picture and diagnosis of dirofilariasis in the maxillofacial area: a series of cases from practice by Kh.A. Buniatian, Yu.V. Khotimska, I.V. Kovach, Yu.Yu. Yaroslavska, O.V. Bondarenko, R.S. Nazaryan

“…Dirofilariasis is a helminthiasis that occurs in carnivorous animals (dogs, cats, foxes, wolves, etc.) and less often in humans, although according to some authors it is believed that the number of infected animals approximately corresponds to the number of infected people. …”
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Unmet medical needs definition and incentives: stakeholders perspectives on the reform of the EU pharmaceutical legislation by Io Wens, Zilke Claessens, Alice Vanneste, Liese Barbier, Rosanne Janssens, Isabelle Huys

“…All stakeholder groups favored including “absence of satisfactory authorized treatment” and “disease seriousness” as defining criteria for UMN. …”
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Extrahepatic portal vein obstruction in children of the first year of life: diagnostic and treatment approaches by O.S. Godik, D.S. Diehtiarova, O.I. Kvilinska

“…No conflict of interests was declared by the authors.…”
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Relationship Between Novel Inflammatory Indices and the Incidence of Postoperative Pneumonia After Endovascular Embolization for Aneurysmal Subarachnoid Hemorrhage by Li S, Li H, Qiu W, Wu B, Wang J, Li Y, Gao H

“…Shaojie Li,1,* Hongjian Li,2,* Weizhi Qiu,1,* Baofang Wu,1 Jiayin Wang,1 Yasong Li,1 Hongzhi Gao1 1Department of Neurosurgery, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, 362000, People’s Republic of China; 2School of Medical Imaging, North Sichuan Medical College, Nanchong, 634700, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yasong Li; Hongzhi Gao, Email 503553815@qq.com; gaohongzhi@fjmu.edu.cnBackground: Accurate identification of the risk of postoperative pneumonia (POP) in aneurysmal subarachnoid hemorrhage (aSAH) is essential for the implementation of stratified treatment. …”
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Indicators Of Morbidity And Mortality From Diseases of the Digestive System in the Krasnodar Krai and the Quality of Medical Care for Gastroenterological Patients by N. V. Korochanskaya, V. M. Durleshter, O. V. Kovalevskaya, S. N. Serikova, K. I. Popandopulo

“…The analysis was carried out according to C 51 “Distribution of deaths by gender, age groups and causes of death” form of the Territorial Authority of the Federal State Statistics Service for the Krasnodar Krai for the period from 2006 to 2018, as well as on the basis of the “Demography” block database of the Parus software of the healthcare management system of the Krasnodar Krai for 6 months of 2019. 1341 medical records of patients receiving outpatient medical care and the medical records of people who had died from digestive diseases in 2017-2019 were reviewed.Results. …”
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The effect of waiting time on ovarian cancer survival in oncology centres, Addis Ababa, Ethiopia: a retrospective cohort study by Abrham Tesfaye Habteyes, Jembere Tesfaye Deressa, Roza Teshome Kassa

“…The main outcome of interest for this study was death due to ovarian cancer. The authors compared the ovarian cancer patients with waiting times ≤ 10 weeks and waiting times > 10 weeks for overall survival rate using the log rank test. …”
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Incidence of diabetic retinopathy and predictors among adult patients with diabetes in central and southern Ethiopia: a multicentre retrospective cohort study by Tagese Yakob, Awoke Abraham, Begidu Yakob, Mesfin Menza Jaldo

“…Thus, health professionals and concerned health authorities should target these factors in their efforts to prevent DR among diabetics.…”
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Analgesic Quality Improvement in Paravertebral Blocks for Pediatric Nuss Procedure: An Exploratory Report on the Effects of Perineural Combined Glucocorticoids by Donham RN, Jin E, Caty MG, Thomas DA, Yuan C, Hollingsworth K, Zhang X, Yanez ND, Li J

“…Rebecca N Donham,1,* Evan Jin,2,* Michael G Caty,3 Donna-Ann Thomas,2 Claire Yuan,4 Kamren Hollingsworth,2 Xuewei Zhang,2 N David Yanez,5 Jinlei Li2,* 1Alabama College of Osteopathic Medicine, Dothan, AL, USA; 2Department of Anesthesiology, Yale University School of Medicine, New Haven, CT, USA; 3Department of Surgery, Yale University School of Medicine, New Haven, CT, USA; 4Harvard University, Cambridge, MA, USA; 5Department of Anesthesiology, Duke University School of Medicine, Durham, NC, USA*These authors contributed equally to this workCorrespondence: Jinlei Li, Department of Anesthesiology, Yale University School of Medicine, 20 York Street, New Haven, CT, 06510, USA, Tel +1 (475) 434-4038, Email jinlei.li@yale.eduPurpose: Pectus excavatum repair using the Nuss procedure is associated with significant postoperative opioid consumption even in the presence of a continuous thoracic paravertebral block.Patients and Methods: A CQI project was initiated by adding combined glucocorticoids as perineural adjuvants to continuous thoracic paravertebral block. …”
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Justification of military neutrality of the Republic of Serbia at a time of erosion of neutrality in Europe by Kajtez Ilija, Starčević Srđan

“…The third chapter lists the advantages in regards to social values implied by the position of military neutrality. Authors conclude that military neutrality represents a favorable strategic option for the Republic of Serbia, not just due to painful collective memory of Serbian citizens of the NATO aggression on Yugoslavia and the support of the Russian Federation to Serbia in regards to Kosovo and Metohija, but also due to the intrinsic values of neutrality which could become an identity attribute and a foundation of the renewal of solidarity in Serbian society.…”
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Patella height ratios diagnose the same healthy knees differently by Martinique Vella-Baldacchino, Alessandra Cipolla, Zahid Asghar, Sally LiArno, Ahmad Faizan, Jean-Noel Argenson, Matthieu Ollivier

“…The inter-rater reliability of both ratios was calculated using kappa statistics. Two authors made all calculations and compared them for consistency using the intraclass correlation coefficient. …”
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Patient education materials for non-specific low back pain and sciatica: a protocol for a systematic review and meta-analysis by Kris Aubrey-Bassler, Amanda Hall, Michelle Swab, Bradley Furlong, Andrea Pike, Holly Etchegary, Georgia Darmonkow

“…Study selection will include a title and abstract scan and full-text review by two authors. Only randomised controlled trials will be included in this review. …”
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The Relationship between Landing Error Scoring System Performance and Injury in Female Collegiate Athletes by Peter Lisman, Joshua N. Wilder, Joshua Berenbach, Enric Jiao, Bethany Hansberger

“…# Background The Landing Error Scoring System (LESS) is a standardized tool used to identify aberrant biomechanical movement patterns during a jump-landing task. Prior authors have examined the value of the LESS in identifying ACL injury risk in athletic populations. …”
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DIGITAL ECONOMY AND RECRUITMENT POTENTIAL: STRATEGICAL INTERCONNECTION AND PROSPECTS by G. Yu. Peshkova, А. Yu. Samarina

“…The perspective directions of higher education and recruitment policy of enterprise and the whole state are identified. The authors have come to the conclusion that rational recruitment policy is an essential part of Russian economy’s digitalisation. …”
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