A synthetic biological secondary metabolite, Lycogenâ¢, produced and extracted from Rhodobacter sphaeroides WL-APD911 in an optimizatioal scale-up strategy by Cheng-Chin Wang, Shi-Ying Huang, Shu-Hung Huang, Zhi-Hong Wen, Jyun-Ying Huang, Wen-Sheng Liu, Hui-Min David Wang

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Efficacy and safety of gut microbiome-targeted treatment in patients with depression: a systematic review and meta-analysis by Bo Pan, Yiming Pan, Yu-Song Huang, Meng Yi, Yuwei Hu, Xiaoyu Lian, Hui-Zhong Shi, Mingwei Wang, Guifen Xiang, Wen-Yi Yang, Zhong Liu, Fangfang Xia

“…Subgroup analyses by geography showed that effectiveness was demonstrated in Asia (SMD −0.46, 95% CI [−0.56, −0.36], I 2  = 36%), while no evidence of effectiveness was found in Europe (SMD −0.07, 95% CI [−0.19, 0.05], I 2  = 55%), America (SMD −0.33, 95% CI [−0.67, 0.02], I 2  = 60%), and Oceania (SMD 0.00, 95% CI [−0.18, 0.18], I 2  = 0%). …”
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Temporal and Spatial Patterns of Wind Erosion Climate Indices and Their Responses to Atmospheric and Oceanic Circulation Patterns in the Chinese Mollisol Region over the Past 61 Ye... by HU Wentao, ZHENG Fenli, GAO Xiaoyu, ZHENG Runhe, FU Jinxia, LI Zhi, ZHANG Jiaqiong

“…The spatial distribution of wind erosion climate indices in the Chinese Mollisol region showed an increasing and then decreasing trend from the northwest to the southeast, and topography was a crucial factor affecting the distribution of wind erosion climate indices. Moreover, the Asia Polar Vortex Intensity Index (APVII) was the most important circulation pattern affecting wind erosion climate indices, and the Pacific/North American Pattern (PNA) also had a significant impact on wind erosion climate indices. …”
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Chromosome-level genome assembly and annotation of the gynogenetic large-scale loach (Paramisgurnus dabryanus) by Lei Zhang, Wanting Zhang, Yingyin Cheng, Yutong Fang, Xin Guan, Ao Gong, Yanxin Jiang, You Duan, Lei Huang, Waqar Younas, Yaping Wang, Mijuan Shi, Xiao-Qin Xia

“…Abstracts The large-scale loach (Paramisgurnus dabryanus; Cypriniformes: Cobitidae) is primarily distributed in East Asia. It is an important economic fish species characterized by fast growth, temperature-dependent sex determination and the ability to breathe air. …”
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The implementation of genome sequencing in rare genetic diseases diagnosis: a pilot study from the Hong Kong genome projectResearch in context by Wai Kei Jacky Lam, Chak Sing Lau, Ho Ming Luk, Lisa Wing Chi Au, Gary C.P. Chan, Will Yap Hang Chan, Shirley Sze Wing Cheng, Timothy Hua Tse Cheng, Li Li Cheung, Yiu Fai Cheung, Josephine Shuk Ching Chong, Annie Tsz Wai Chu, Claudia Ching Yan Chung, Kin Lai Chung, Cheuk Wing Fung, Eva Lai Wah Fung, Yuan Gao, Stephanie Ho, Shirley Pik Ying Hue, Chi-Ho Lee, Tsz Leung Lee, Philip Hei Li, Hei Man Lo, Ivan Fai Man Lo, Herbert Ho Fung Loong, Becky Mingyao Ma, Wei Ma, Shirley Yin Yu Pang, Wai-Kay Seto, Steven Wai Kwan Siu, Ho So, Yuk Him Tam, Wenshu Tang, Rosanna Ming Sum Wong, Desmond Yat Hin Yap, Maggie Lo Yee Yau, Brian Hon Yin Chung, Su-Vui Lo

“…However, the impact of GS on patients with RDs is yet to be investigated among genome projects in Asia. The Hong Kong Genome Project (HKGP) was implemented to benefit patients and families with RDs in Hong Kong, and to increase the inclusiveness of Chinese genomic data. …”
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New Species of <i>Diaporthales</i> (<i>Ascomycota</i>) from Diseased Leaves in Fujian Province, China by Xiayu Guan, Taichang Mu, Nemat O. Keyhani, Junya Shang, Yuchen Mao, Jiao Yang, Minhai Zheng, Lixia Yang, Huili Pu, Yongsheng Lin, Mengjia Zhu, Huajun Lv, Zhiang Heng, Huiling Liang, Longfei Fan, Xiaoli Ma, Haixia Ma, Zhenxing Qiu, Junzhi Qiu

“…This study contributes to our understanding on the biodiversity of diaporthalean fungi that are inhabitants of the phyllosphere of trees native to Asia.…”
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Identification and Mass Spectrometric Fragmentation Pathways of Chemical Components in the Traditional Chinese Medicine Formula of Jiuwei Decoction by Jia-yu ZHAO, Yue-guang LYU, Tong XIN, Qian-qian GUO, Wen-ying ZHANG, Jin-hong LI, Hong-yu XUE, Qiang MA

“…Traditional Chinese medicine (TCM), both a longstanding medical practice in Asia and an increasingly utilized supplement or alternative medicine in Western countries, has become a focal point within the life sciences in recent years. …”
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Mechanisms of blaIMP-4 dissemination across diverse carbapenem-resistant clinical isolates by Ying Fu, Faye C. Morris, Stephanie C. Pereira, Xenia Kostoulias, Yan Jiang, Callum Vidor, Galain Williams, Yogi Srikhanta, Nenad Macesic, Yunsong Yu, Dena Lyras, Anton Y. Peleg

“…ABSTRACT: Objective: The IMP-4 carbapenemase is an endemic cause of carbapenem resistance in the Asia-Pacific region. Our aim was to determine the dissemination mechanism of the blaIMP-4 gene. …”
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Investigating the Effect of Chicken Manure and Potassium Sulfate on the Physiological Properties of Fenugreek )Trigonella foenum-graecum L.( Medicinal Plant by Mohammad hossein Aminifard, Sajjad Nadafa, Hassan Hassan, Mehdi Jahani

“….), is an annual plant found in many countries in Africa, Asia, and Europe, and India is the largest producer in the world. …”
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Molecular Phylogenetics and Estimation of Evolutionary Divergence and Biogeography of the Family Cordycipitaceae (Ascomycota, Hypocreales) by Huili Pu, Jiao Yang, Nemat O. Keyhani, Lixia Yang, Minhai Zheng, Chenghao Qiu, Yuchen Mao, Junya Shang, Yongsheng Lin, Chengjie Xiong, Longbing Lin, Pengyu Lai, Yanbin Huang, Xin Yuan, Huiling Liang, Longfei Fan, Xiaoli Ma, Chunjin Qiu, Junzhi Qiu

“…The historical biogeography of <i>Akanthomyces sensu lato</i> was reconstructed using reconstructing ancestral state in phylogenies (RASP) analysis, indicating that it most likely originated in Asia. Combined morphological characterization and phylogenetic analyses were used to identify and taxonomically place five species within Cordycipitaceae. …”
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Preparedness, prevention and control related to zoonotic avian influenza by EFSA Panel on Animal Health and Animal Welfare (AHAW), ECDC, Julio Alvarez, Anette Boklund, Sabine Dippel, Fernanda Dórea, Jordi Figuerola, Mette S. Herskin, Virginie Michel, Miguel Ángel Miranda Chueca, Eleonora Nannoni, Søren Saxmose Nielsen, Romolo Nonno, Anja B. Riber, Jan Arend Stegeman, Karl Ståhl, Hans‐Hermann Thulke, Frank Tuyttens, Christoph Winckler, Claire Brugerolles, Thorsten Wolff, Anna Parys, Erika Lindh, Neus Latorre‐Margalef, Marie‐Anne Rameix Welti, Ralf Dürrwald, Ramona Trebbien, Sylvie Van der Werf, Magnus Gisslén, Isabella Monne, Alice Fusaro, Claire Guinat, Alessio Bortolami, Leonidas Alexakis, Theresa Enkirch, Olov Svartstrom, Katriina Willgert, Francesca Baldinelli, Ludovica Preite, Malin Grant, Alessandro Broglia, Angeliki Melidou

“…AI viruses (AIVs) carrying multiple adaptive mutations and traits belonged to both low and highly pathogenic subtypes, mainly to A(H9N2), A(H7N9), A(H5N6) and A(H3N8), were sporadic and primarily detected in Asia. In the EU/EEA, H5Nx viruses of clade 2.3.4.4b, which have increased opportunities for evolution due to widespread circulation in birds and occasional cases/outbreaks in mammals, have acquired the highest number of zoonotic traits. …”
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Longitudinal associations of flare and damage accrual in patients with systemic lupus erythematosus by Rangi Kandane-Rathnayake, Sang-Cheol Bae, Zhanguo Li, Shereen Oon, Vera Golder, Mandana Nikpour, Masayoshi Harigai, Zhuoli Zhang, Eric Morand, Chak Sing Lau, Worawit Louthrenoo, Alberta Hoi, Sandra Navarra, Sean O’Neill, Shue-Fen Luo, Yanjie Hao, Yasuhiro Katsumata, Dominique Milea, Aisha Lateef, Laniyati Hamijoyo, Sargunan Sockalingam, Madelynn Chan, Jiacai Cho, Leonid Zamora, Fiona Goldblatt, Yeong-Jian Jan Wu, Xiaomeng Xu, Aldo A Navarro Rojas

“…Objective To estimate the prevalence of organ damage (damage) and flare and to examine longitudinal associations between flares and subsequent damage accrual, in patients with systemic lupus erythematosus (SLE).Methods Patients enrolled in the Asia Pacific Lupus Collaboration cohort with ≥3 years of prospectively captured data were studied. …”
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Global, regional, and national burdens of heart failure in adolescents and young adults aged 10–24 years from 1990 to 2021: an analysis of data from the Global Burden of Disease St... by Chengzhi Yang, Yuhe Jia, Changlin Zhang, Zening Jin, Yue Ma, Xuanye Bi, Aiju Tian

“…Noticeable changes in HF prevalence were found in 1994, 2001, 2004, 2010, and 2018. Regionally, East Asia had the most pronounced increase in HF prevalence rate (AAPC = 1.35 [1.28–1.43]) and YLDs rate (AAPC = 1.32 [1.27–1.38]), while the highest HF prevalence rates per 100,000 population were observed in High-income North America (232 [185.4–292]). …”
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Features and evolutionary adaptations of the mitochondrial genome of Garuga forrestii W. W. Sm by Rong Chen, Rong Chen, Rong Chen, Rong Chen, Rui Rao, Rui Rao, Rui Rao, Rui Rao, Chun Wang, Chun Wang, Chun Wang, Chun Wang, Dongbo Zhu, Dongbo Zhu, Dongbo Zhu, Dongbo Zhu, Fen Yuan, Fen Yuan, Fen Yuan, Fen Yuan, Liangliang Yue, Liangliang Yue, Liangliang Yue, Liangliang Yue

“…It enhances our understanding of the species' biogeography in tropical Southeast Asia and Southwest China, providing key information on the evolutionary history of this genus.…”
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Causes of growing middle-to-upper tropospheric ozone over the northwest Pacific region by X. Ma, X. Ma, J. Huang, J. Huang, M. I. Hegglin, M. I. Hegglin, P. Jöckel, T. Zhao

“…Yet, these changes remain poorly quantified through observations in East Asia. Concerns also persist regarding the data quality of the ozonesondes available at the World Ozone and Ultraviolet Radiation Data Centre (WOUDC) for this region. …”
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Recombinase-based amplification coupled with lateral flow chromatography for the specific and sensitive detection and identification of Leishmania major in cutaneous leishmaniasis... by Insaf Bel Hadj Ali, Yusr Saadi-Ben Aoun, Imen Khammeri, Hejer Souguir, Emna Harigua-Souiai, Hamed Chouaieb, Ahmed S. Chakroun, Meryem Lemrani, Aicha Kallel, Kalthoum Kallel, Nabil Haddad, Oussaima El Dbouni, Rhea N. Coler, Rhea N. Coler, Rhea N. Coler, Steven G. Reed, Akila Fathallah-Mili, Akila Fathallah-Mili, Ikram Guizani

“…L. major is hyperendemic in many countries in Africa, the Middle East, and Asia, where other species co-occur with different endemicity levels according to the situations. …”
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Aerosol layer height (ALH) retrievals from oxygen absorption bands: intercomparison and validation among different satellite platforms, GEMS, EPIC, and TROPOMI by H. Kim, H. Kim, X. Chen, X. Chen, J. Wang, J. Wang, J. Wang, J. Wang, Z. Lu, Z. Lu, Z. Lu, M. Zhou, G. R. Carmichael, G. R. Carmichael, S. S. Park, J. Kim

“…In this study, we evaluate ALH products retrieved using oxygen absorption measurements from multiple satellite platforms: the Geostationary Environment Monitoring Spectrometer (GEMS) focusing on Asia, the Earth Polychromatic Imaging Camera (EPIC) in deep space, and the polar-orbiting TROPOspheric Monitoring Instrument (TROPOMI). …”
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Global, regional, and national epidemiology of childhood neuroblastoma (1990–2021): a statistical analysis of incidence, mortality, and DALYsResearch in context by Jusen Nong, Cheng Su, Changhua Li, Congjun Wang, Wei Li, Yong Li, Peng Chen, Yanqiang Li, Zihao Li, Xinjin She, Zuxin Yuan, Sentian Liu, Chao Chen, Qian Liao, Yige Luo, Bo Shi

“…Among the five Sociodemographic Index (SDI) regions, the highest EAPCs were observed in the low-to-mid SDI regions for incidence (1.87%; 95% CI, 1.64%–2.10%), mortality (1.22%; 95% CI, 1.09%–1.34%), and DALYs (1.36%; 95% CI, 1.15%–1.57%). Regionally, Central Asia exhibited the fastest annual increase in incidence (EAPC = 2.76%; 95% CI, 2.18%–3.34%). …”
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Development of indicators to measure health system capacity for quality abortion care in 10 countries: a rapid assessment of a measurement framework and indicators by Leopold Ouedraogo, Katy Footman, Fahdi Dkhimi, Bela Ganatra, Mohamed Ali, Antonella Lavelanet, Souleymane Zan, Shikha Bansal, Karima Gholbzouri, Eman Aly, Nilmini Hemachandra, Laurence Läser, Ulrika Rehnstrom Loi, Dina Gbenou, Yelmali Hien, Asmani Chilanga, Hayfa Elamin, Priya Karna, Laurence Codjia, Heidi Bart Johnston, Ghislaine Glitho Alinsato, Sithembile Dlamini-Nqeketo, Lisa Hedman, Md Khurshid Alam Hyder, Theopista John, Amrita Kansal, Belete Mihretu, Pamela Amaka Onyiah, Sikander Qais, Ellen Thom, Meera Upadhyay, Qudsia Uzma

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Antenatal Care - How to ensure quality! by Lubna Ejaz

“…Pakistan is still contributing 14.47% of the total maternal deaths in South Asia16. In this scenario, it becomes the professional responsibility of the public tertiary care hospitals to develop evidence-based strategies for improvement in ANC quality. …”
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