GLP1R boosts survival, migration and invasion of endometrial cancer cells and protects against ferroptotic cell death by Wu Li, Wen Lyu, Songjun Liu, Fan Ruan, Xinmei Zhang

“…Cell viability, migration and invasion were significantly reduced, while cell cycle arrest and apoptosis were induced following GLP1R knockdown. …”
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Alleviatory effect of isoquercetin on benign prostatic hyperplasia via IGF-1/PI3K/Akt/mTOR pathway by Young-Jin Choi, Meiqi Fan, Nishala Erandi Wedamulla, Yujiao Tang, Eun-Kyung Kim

“…In BPH-1 cells, IQ led to G0/G1 arrest and suppressed the expression of proliferation factors while inducing apoptosis. …”
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What Drives Embryo Development? Chromosomal Normality or Mitochondria? by A. Bayram, I. Elkhatib, A. Arnanz, A. Linan, F. Ruiz, B. Lawrenz, H. M. Fatemi

“…Objective. To report the arrest of euploid embryos with high mtDNA content. …”
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Administration of Recombinant Heat Shock Protein 70 Delays Peripheral Muscle Denervation in the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis by David J. Gifondorwa, Ramon Jimenz-Moreno, Crystal D. Hayes, Hesam Rouhani, Mac B. Robinson, Jane L. Strupe, James Caress, Carol Milligan

“…Injections of the protein appeared to arrest denervation with preserved large myelinated peripheral axons, and reduced glial activation.…”
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Multiorgan Failure and Refractory Lactic Acidosis due to Pasteurella multocida Septicemia in a Patient with No Animal Exposure by Damaris Pena, Yaneidy Santana, Jose Perez Lara, Efrain Gonzalez, Misbahuddin Khaja

“…The patient subsequently died of cardiopulmonary arrest due to multiorgan failure with refractory shock. …”
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Research advances in Pimpinella thellungiana: Nutrients, bioactive compounds, and functional properties benefitting livestock by Shuxian Zhang, Minglu Yang, Tao Xu, Qiongxian Yan, Allan Degen, Xiaoling Zhou

“…Growth retardation affects the health and production of livestock, while overexertion can cause sudden cardiac arrest. Both cases are considered to be metabolic disorders and are detrimental to livestock production. …”
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RNA N4‐acetylcytidine modification and its role in health and diseases by Qiang Wang, Yixiao Yuan, Qiang Zhou, YingDong Jia, Jing Liu, GuangJun Xiao, Chunhong Li, Xiulin Jiang

“…Furthermore, this review delves into the central roles and molecular mechanisms of ac4C modification in regulating malignant proliferation, cell cycle arrest, EMT, drug resistance, cell death, cancer metabolism, and tumor immunotherapy. …”
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Cannabidiol attenuates lipid metabolism and induces CB1 receptor-mediated ER stress associated apoptosis in ovarian cancer cells by Xuanhe Fu, Zhixiong Yu, Fang Fang, Weiping Zhou, Yuxin Bai, Zhongjia Jiang, Biao Yang, Ye Sun, Xing Tian, Guangyan Liu

“…Conversely, by supplementation with unsaturated fatty acid or blocking CB1R, ER stress or reactive oxygen species (ROS) signals with specific inhibitors could significantly relieve CBD induced, dose-dependent, ER stress associated apoptosis, G0-G1 phase arrest, and mitochondrial dysfunction. Taken collectively, these data indicate that CBD may disrupt lipid metabolism, and lead to ER stress-related apoptosis in OCs. …”
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Treating Metabolic Dysregulation and Senescence by Caloric Restriction: Killing Two Birds with One Stone? by Lara Russo, Serena Babboni, Maria Grazia Andreassi, Jalil Daher, Paola Canale, Serena Del Turco, Giuseppina Basta

“…Cellular senescence is a state of permanent cell cycle arrest accompanied by metabolic activity and characteristic phenotypic changes. …”
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Harnessing the anticancer potential of Piper nigrum: a synergistic approach to chemotherapy enhancement and reduced side effects by Hesti Lina Wiraswati, Ilma Fauziah Ma’ruf, Nur Akmalia Hidayati, Julia Ramadhanti, Daniela Calina, Javad Sharifi-Rad

“…Piper nigrum, a widely available spice with a rich history in traditional medicine, contains bioactive compounds such as piperine, which have demonstrated significant anticancer activities including cell cycle arrest, apoptosis induction, and inhibition of tumor growth and metastasis. …”
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Tegaserod maleate exerts anti-tumor effects on prostate cancer via repressing sonic hedgehog signaling pathway by Maoping Cai, Shengdong Ge, Yaying Hong, Yao Chen, Yang-Zi Ren, Dacai Zhong, Mingkun Chen, Yuan Liu, Zhe-Sheng Chen, Ninghan Feng, Zhanghui Chen, Shan-Chao Zhao

“…In the current study, we found that tegaserod maleate (TM), an FDA-approved agent, inhibited proliferation, colony formation, migration as well as invasion, caused the arrest of the cell cycle, and promoted apoptosis of PCa cells in vitro. …”
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The Geobattery Concept: A Geothermal Circular Heat Network for the Sustainable Development of Near Surface Low Enthalpy Geothermal Energy to Decarbonise Heating by Andrew Fraser-Harris, Christopher Ian McDermott, Mylène Receveur, Julien Mouli-Castillo, Fiona Todd, Alexis Cartwright-Taylor, Andrew Gunning, Mark Parsons

“…We show that thermal recharge under these conditions has the potential to arrest subsurface temperature declines associated with closely spaced borehole heat exchangers, ensure the long-term sustainability of shallow geothermal resources for generations to come, and play an important role in the decarbonisation of heating.…”
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The crosstalk between senescence, tumor, and immunity: molecular mechanism and therapeutic opportunities by Zehua Wang, Chen Chen, Jiaoyu Ai, Yaping Gao, Lei Wang, Shurui Xia, Yongxu Jia, Yanru Qin

“…Abstract Cellular senescence is characterized by a stable cell cycle arrest and a hypersecretory, proinflammatory phenotype in response to various stress stimuli. …”
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The proline-rich antimicrobial peptide Api137 disrupts large ribosomal subunit assembly and induces misfolding by Simon Malte Lauer, Jakob Gasse, Andor Krizsan, Maren Reepmeyer, Thiemo Sprink, Rainer Nikolay, Christian M. T. Spahn, Ralf Hoffmann

“…Abstract The proline-rich antimicrobial designer peptide Api137 inhibits protein expression in bacteria by binding simultaneously to the ribosomal polypeptide exit tunnel and the release factor (RF), depleting the cellular RF pool and leading to ribosomal arrest at stop codons. This study investigates the additional effect of Api137 on the assembly of ribosomes using an Escherichia coli reporter strain expressing one ribosomal protein per 30S and 50S subunit tagged with mCherry and EGFP, respectively. …”
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An analysis of the cultivation, consumption and composition of home-grown cannabis following decriminalisation in the Australian Capital Territory by Cilla Zhou, Isobel Lavender, Rebecca Gordon, Danielle McCartney, Richard C. Kevin, Miguel A. Bedoya-Pérez, Iain S. McGregor

“…Respondents identified various grey areas in current legislation that might lead to inadvertent criminal activity, and many (52%) remained anxious about arrest. In general, recent legislative changes appear to support community needs. …”
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Ambient fine particulate matter provokes multiple modalities of cell death via perturbation of subcellular structures by Yán Wāng

“…Furthermore, PM2.5 exposure disrupts genetic and epigenetic regulation, often resulting in cell cycle arrest and exacerbating cellular damage. The composition, concentration, and seasonal variability of PM2.5 modulate these effects, underscoring the complexity of PM2.5-induced cellular dysfunction. …”
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Genistein Implications in Radiotherapy: Kill Two Birds with One Stone by Xiongxiong Liu, Tong Zheng, Yanyu Bao, Ping Li, Ting Zhao, Yan Liu, Hui Wang, Chao Sun

“…Conversely, genistein increases the radiosensitivity of tumor cells through specific mechanisms such as the inhibition of DNA repair, the arrest of the cell cycle in the G₂/M phase, the generation of reactive oxygen species (ROS), and the modulation of apoptosis. …”
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Large-scale reservoir modeling of the Vendenheim geothermal site (France) by J. Abreu-Torres, G. Hutka, G. Hutka, G. Blöcher, G. Blöcher, M. Cacace, V. Magnenet, J. Schmittbuhl

“…<p>During the Vendenheim deep geothermal project (Strasbourg Eurometropole, France), large induced seismic events led to the arrest of the project. Two important features of the induced seismicity were unexpected: the large distance to the wells of a cluster of seismic events (4–5 km) and the occurrence of the largest event Mlv3. 9 at the bottom of the wells, six months after shut-in. …”
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Color Doppler Score: A New Approach for Monitoring a Large Placental Chorioangioma by Maria Angelica Zoppi, Alessandra Piras, Ambra Iuculano, Maurizio Arras, Federica Mulas, Maria Carmela Fadda, Sergio Cossu, Giovanni Monni

“…The ultrasonographic scan showed an increase of the mass size at the second and third exams and was followed by an arrest of the growth persisting for the rest of the pregnancy. …”
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Influence of breed and environment on leukocyte telomere length in cattle by N. S. Yudin, A. V. Igoshin, G. A. Romashov, A. A. Martynov, D. M. Larkin

“…When telomeric DNA is truncated to a critical length, cell ageing, cell cycle arrest, and apoptosis are induced. As a result, telomere length can be considered as a predictor of health risks and an individual’s lifespan. …”
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