Deguelin inhibits the proliferation of human multiple myeloma cells by inducing apoptosis and G2/M cell cycle arrest: Involvement of Akt and p38 MAPK signalling pathway by Sun Kening, Chen Ping, Zhang Liang, Lu Zhidong, Jin Qunhua

Subjects: Get full text

Enhanced Activity by NKCC1 and Slc26a6 Mediates Acidic pH and Cl− Movement after Cardioplegia-Induced Arrest of db/db Diabetic Heart by Minjeong Ji, Seok In Lee, Sang Ah Lee, Kuk Hui Son, Jeong Hee Hong

“…We hypothesized that ion transporters might be regulated differently in the diabetic heart and that the differentially regulated ion transporters may involve in ion imbalance of the diabetic heart after cardioplegic arrest. In this study, we modified the Langendorff-free cardioplegia method and identified the involved ion transporters after cardioplegia-induced arrest between wild type and db/db heart. …”
Get full text

Ampelopsin induces MDA-MB-231 cell cycle arrest through cyclin B1-mediated PI3K/AKT/mTOR pathway in vitro and in vivo by Meng Minjun, Yang Qiaolu, Ouyang Zhong, Yang Qingmo, Wu Xinyi, Huang Yufan, Su Yonghui, Chen Shuanglong, Chen Wenlin

Subjects: Get full text

Correlation between the white blood cell/platelet ratio and 28-day all-cause mortality in cardiac arrest patients: a retrospective cohort study based on machine learning by Huai Huang, Guangqin Ren, Shanghui Sun, Zhi Li, Yongtian Zheng, Lijuan Dong, Shaoliang Zhu, Xiaosheng Zhu, Wenyu Jiang

Subjects: “…cardiac arrest (CA)…”
Get full text

La répression anticommuniste du printemps 1940 au printemps 1941 : l’affaire de l’usine Breguet d’Aubervilliers by Louis Poulhès

Subjects: Get full text

Effects of intrathecal administration of sodium nitroprusside and nicardipine on cerebral pial microcirculation, cortical tissue oxygenation, and electrocortical activity in the early post-resuscitation period in a porcine cardiac arrest model. by Hyoung Youn Lee, Najmiddin Mamadjonov, Kyung Woon Jeung, Yong Hun Jung, Wan Young Heo, Yong Soo Cho, Byung Kook Lee, Tag Heo

“…Recent studies suggested intrathecal vasodilator administration as a therapy to mitigate post-ischemic cerebral hypoperfusion following cardiac arrest. We examined the effects of two commonly used intrathecal vasodilators, sodium nitroprusside (SNP) and nicardipine, on cerebral pial microcirculation, cortical tissue oxygen tension (PctO2), and electrocortical activity in the early post-resuscitation period using a porcine model of cardiac arrest. …”
Get full text

Now-Time Poetics: Under The Sign Of Benjamin by Michael Heller

Subjects: Get full text

Pathogenic variants of TUBB8 cause oocyte spindle defects by disrupting with EB1/CAKP5 interactions and potential treatment targeting microtubule acetylation through HDAC6 inhibiti... by Hui Luo, Jianhua Chen, Cao Li, Tian Wu, Siyue Yin, Guangping Yang, Yipin Wang, Zhihan Guo, Saifei Hu, Yanni He, Yingnan Wang, Yao Chen, Youqiang Su, Congxiu Miao, Yun Qian, Ruizhi Feng

Subjects: Get full text

Bland–Altman plot to assess the consistency of arterial and venous blood lactate in the emergency room: a retrospective cohort study by Yongkai Li, Xiaojing He, Dandan Li, Xin Yuan, Jun Xu, Jianzhong Yang

Subjects: Get full text

From Infection to Tumor: Exploring the Therapeutic Potential of Ciprofloxacin Derivatives as Anticancer Agents by Hesham M. Hassan, Roket Hassan, Ranya Mohammed Elmagzoub, Ahmed Al-Emam, Konstantinos Kossenas, Ahmed S. Abdel-Samea, Hazim O. Khalifa, Suleyman Akocak, Stefan Bräse, Hamada Hashem

Subjects: Get full text

Altered zygotic gene expression caused by sperm with Tdrd6 variants disrupts early embryonic development by Zhijie Hu, Yuqi Zhang, Renfei Cai, Qiuju Chen, Haiyan Guo, Danjun Li, Weidong Lin, Hongxi He, Haibo Wu, Yali Liu, Bin Li, Qianwen Xi, Hongyuan Gao, Jian Zhang, Qifeng Lyu, Yanping Kuang, Xuefeng Lu

Subjects: Get full text

Hypothermia regulates mitophagy and apoptosis via PINK1/Parkin-VDAC 3 signaling pathway during oxygen-glucose deprivation/recovery injury by Luying Zhang, Song Yang, Hao Cui, Chenchen Hang, Xingsheng Wang, Le An, Zhenyu Shan, Zhen Liang, Rui Shao, Ziren Tang

Subjects: Get full text

Students’ and Physical Education Professionals’ Knowledge About First Aid Maneuvers in Cardiopulmonary Resuscitation and Syncope: A Cross-Sectional Study

Subjects: Get full text

Study on the protective effect of naringin-regulated lncRNA GAS5 against mitochondrial apoptosis in osteoarthritic chondrocytes by LIN Qin, ZHU Yingkai, LIN Yanming, LAN Shujie, CHEN Changxing, FU Changlong

Subjects: “…Long-chain noncoding RNA Growth arrest specificity 5…”
Get full text

Standard <i>vs.</i> mass training in basic life support and defibrillation: a prospective analysis among Italian high school students within a municipal project by Luca Dal Corso, Massimiliano Aldegheri, Elena Anselmi, Alberto Burro, Francesca Moretti, Fabio Rossi, Simone Sebastiani, Davide Silvagni, Michele Zandonà, Maria Angela Cerruto

Subjects: Get full text

Is Continuous Chest compression CPR by Untrained Bystanders More Effective than Conventional CPR with Rescue Breathing?

Subjects: Get full text

The tragic route of Baron Tiesenhausen by S. A. Papkov

Subjects: Get full text

STUDY OF DYNAMIC FRACTURE OF X80 NATURAL GAS PIPELINE by LV JinJie, ZHAO JunHua, YU PeiShi

Subjects: Get full text

Redox-dependent purine degradation triggers postnatal loss of cardiac regeneration potential by Yuichi Saito, Yuki Sugiura, Akane Sakaguchi, Tai Sada, Chihiro Nishiyama, Rae Maeda, Mari Kaneko, Hiroshi Kiyonari, Wataru Kimura

Subjects: “…Cell cycle arrest…”
Get full text

Long-Term Therapeutic Effects of ²²⁵Ac-DOTA-E[c(RGDfK)]₂ Induced by Radiosensitization via G2/M Arrest in Pancreatic Ductal Adenocarcinoma by Mitsuyoshi Yoshimoto, Kohshin Washiyama, Kazunobu Ohnuki, Ayano Doi, Miki Inokuchi, Motohiro Kojima, Brian W. Miller, Yukie Yoshii, Anri Inaki, Hirofumi Fujii

“…<b>Results</b>: ²²⁵Ac-DOTA-RGD₂ demonstrated potent cytotoxicity against cells expressing α_vβ₃ or α_vβ₆ integrins and induced G2/M arrest and γH2AX expression as a marker of double-stranded DNA breaks. …”
Get full text