Effect of Zhuanggu Jianxi Decoction on Synovitis in Knee Osteoarthritis Rabbits via LXRs/NF-κB Pathway by CHEN Peng, GUO Jiemei, XIAO Yan, WANG Jianhui, SU Youxin

“…Compared with the Zhuanggu Jianxi decoction group, the protein expression of LXRα and N-CoR in both the LXRα and N-CoR inhibitor groups were significantly decreased (<italic>P</italic>&lt;0.05), and the protein expression of P50 and P65 were significantly increased (<italic>P</italic>&lt;0.05).ConclusionZhuanggu Jianxi decoction could improve the pathological manifestations of synovial lining cell hyperplasia and the disorder arrangement, inflammatory cell infiltration and fibrous tissue hyperplasia, reduce the content of inflammatory related indexes in tissues, so as to reduce the inflammatory response of KOA synovial tissue in rabbits, which may be related to the up-regulation of LXRα and N-CoR protein expression in synovial cells via LXRs/NF-κB pathway in synovial tissue, thereby down-regulating P50 and P65 protein to reduce IL-1β, TNF-α, MMP-3 and MMP-13.…”
Get full text

Crack of a helicopter main rotor actuator attachment: failure analysis and lessons learned by L. Allegrucci, F. De Paolis, A. Coletta, M. Bernabei

“…This condition is mainly related to the presence of coarse-grained and aligned CuAl2 precipitates. This arrangement is due to an overheating (more than 507°C) or to a cooling process carried out too slowly.Microstructural analysis was carried out on three items: 1) a large portion of the broken actuator attachment; 2) on a servoactuator coming from the same production batch; 3) on a servo actuator coming from a different production batch.The microstructure from the broken actuator attachment showed a great amount of precipitates (second phases) lengthwise aligned to the boundary grain, pores, and also cavities and dendritic globular formations.Analysis results, morphology evidences and reference images available on scientific literature were found to be in excellent agreement and validated the embrittlement and subsequent SCC mechanism hypotesis (intergranular failure propagation). …”
Get full text

Effect of Xingbi Gel Nasal Drops on Rats with Allergic Rhinitis Based on the Nasal Mucosa-Hippocampus Neuroimmune Mechanism by FAN Xueqi, QIU Caixia, YAN Shuiping, ZHUANG Xiangli, AI Si, GUO Lihua, ZHENG Jian

“…Compared with the model group, IgE and TGF-β1 contents in serum in both the traditional Chinese medicine group and the western medicine group were significantly lower (<italic>P</italic>&lt;0.05). (4) Pathological changes of nasal mucosa and EOS counts: the nasal mucosa in the model group was edematous and the epithelial cells were arranged in disorder; the nasal mucosa edema were alleviated significantly in the traditional Chinese medicine group and the western medicine group after treatment, and the epithelial cell structure was more intact. …”
Get full text

Fálétí’s Philosophical Sensibility by Adeshina Afolayan

“…Philosophy and literature, equally, offer critical evaluation of existing and possible forms of political arrangements, beliefs and practices. In addition, they provide insights into political concepts and justification for normative judgements about politics and society. …”
Get full text

Neuroprotective Effect of Crocin on Rats with Focal Cerebral Ischemia-Reperfusion Injury Based on TLR4/NF-κB Pathway by LI Xiaolei, ZHU Haisheng, MA Ruijuan, HU Ke, FENG Lina, WANG Xudong

“….); western blot was used to detect the expression of toll-like receptor 4 (TLR4), nuclear factor-κB p65 (NF-κB p65), p-NF-κB p65, IκBα, p-IκBα, Cleved Caspase-3, B-lymphoma-2 gene (Bcl-2), Bcl-2-related X protein (Bax).Results(1) Neurological function, cerebral infarction rate and cerebral water content: compared with the sham operation group, the mNSS score, cerebral infarction rate, cerebral water content in the model group increased significantly (<italic>P</italic>&lt;0.05); compared with the model group, the mNSS score, cerebral infarction rate, cerebral water content in the crocin group and the crocin + lipopolysaccharide group decreased significantly (<italic>P</italic>&lt;0.05); compared with the crocin group, the mNSS score, cerebral infarction rate, cerebral water content in the crocin + lipopolysaccharide group increased significantly (<italic>P</italic>&lt;0.05). (2) Pathological changes and apoptosis of cortical neurons: the cortical neurons in the sham operation group showed normal morphology and complete structure; the pathological changes of cortical neurons such as disordered arrangement, decreased number, vacuolar degeneration, hyperchromatic cytoplasmic pyknosis, unclear nuclear membrane boundary, inflammatory cell infiltration were observed in the model group; the pathological changes of cortical neurons in the crocin group were significantly improved. …”
Get full text

Suitable Sowing Date Method of Winter Wheat at the County Level Based on ECMWF Long-Term Reanalysis Data by LIU Ruixuan, ZHANG Fangzhao, ZHANG Jibo, LI Zhenhai, YANG Juntao

“…The research results can not only provide decision-making reference for winter wheat yield assessment in Qihe county, but also provide an important theoretical basis for scientifically arrangement of agricultural production.…”
Get full text

Julius Kruopis – the pioneer of applied statistics in Lithuania by Vilijandas Bagdonavičius, Vydas Čekanavičius, Rūta Levulienė, Pranas Vaitkus

“…Under his supervision Vanda Bikelienė (Asymptotic distribution of sums of samples from finite populations, 1981) and  Natalja Kosareva  (Asymptotic analysis of statistics distributions in the scheme of sets of particles arrangement with equal probabilities, 1986) defended their doctoral theses in mathematics. …”
Get full text

Pierre et carrières dans la Saintonge antique : identification, usages et diffusion by Jacques Gaillard, Egle Conforto

“…It remains for the archaeometrist to count, sort, and assign them false colours, as well as to arrange them on individualised layers with the help of image processing software in order to establish discriminating statistical groups of mineral species. …”
Get full text

INTERNATIONAL FORUM OF AMERICAN SOCIETY FOR ENGINEERING EDUCATION by Vasily Ivanov, Yulia Ziyatdinova

“…Kazan National Research Technological University presented an oral report on an integrated university/industry program of improving Russian industrial trainers at continuing professional development division technical session.The lastday ofthe Conference was remarkable for the ASEE International Council meeting which gathered the representatives of different international societies to discussthe prospects of collaboration with ASEE. The preliminary arrangements were made about the possible participation of Kazan National Research Technological University and National Research Tomsk Polytechnic University in the 2015 International Forum to represent the partner society, Association for Engineering Education of Russia.…”
Get full text

Call for Papers: Constitutions and Intergenerational Justice by IF and FRFG

“…Madison disagreed and referred to the uncertainty that would emerge from such an arrangement. Thomas Paine sided with Jefferson and formulated the following famous sentence: ‘Every age and generation must be as free to act for itself in all cases as the ages and generations which preceded it.’ …”
Get full text

Developing an effective teaching model in order to improve the educational level of schools by Mehdi Mohammadi, fardin Abdollahy, Rafigh Hasani

“…In order to analyze the data, the theme analysis method was used.Research findingsIn order to examine and answer the research question, after collecting, arranging and organizing the codes resulting from each interview and based on the thematic method, key words and points in the form of an index was extracted from the interview text. …”
Get full text

Designing a Digital Branding Pattern in Healthy Agricultural Products by Abolghasem Mohammadnezhad Ali Zamini, Arezo Ahmadi danyali, Mahmoud Ahmadi Sharif

“…The country of Iran is proficient in the production of agricultural products, and produces all kinds of agricultural and garden products every year; all Iranian products have a high capacity to be branded due to Iran's special climatic conditions and the country's four season, but unfortunately, many products that are at a high level in terms of quality are bought in bulk and exported to other countries and sold under the brand of these companies; therefore, the lack of a suitable brand is one of the weaknesses of Iran's agriculture, which demands that this sector be given a proper arrangement. Producers of healthy agricultural products should understand the potential of the Internet as a branding tool in the agricultural sector because the Internet can be a powerful branding tool for healthy agricultural products beyond labels and brochures. …”
Get full text

Presenting the Model of Effective Factors on Smart Governance in the Country by Ghaem Gheiravani, Mohammad Montazeri, Shams Sadat Zahedi

“…The results of the analysis showed that the appropriate foundation scenarios in the field of citizenship education and raising awareness, popular participation and citizenship and private sector participation, making arrangements to increase the budget in the field of smartness, and municipal support of the smart government have the most adaptive value in the future of smart urban governance of the city of Rasht. …”
Get full text

Quais et ouvrages portuaires romains de Rouen/Rotomagus (Seine-Maritime) by Marie-Clotilde Lequoy

“…On this side, one finds two massive posts, as well as 12 piles carefully arranged in a joined manner so as to form a single load-bearing element. …”
Get full text

Comparative Ethics of Modern Payment Models by Jacob Riegler

“…Physician Compensation Arrangements and Financial Performance Incentives in US Health Systems. …”
Get full text