The Palliative Management of Refractory Cirrhotic Ascites Using the PleurX© Catheter by Jason Reinglas, Kayvan Amjadi, Bill Petrcich, Franco Momoli, Thomas Shaw-Stiffel

“…All patients were treated for SBP successfully with antibiotics. Conclusion. Use of the PleurX catheter for the management of RCA carries a high risk for infection when the catheter remains in situ for more than 3 months but has an excellent patency rate and did not result in significant renal injury.…”
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Heme alters biofilm formation in Mycobacterium abscessus by Hadia Aftab, Jessica Samudio, Grace Wang, Lily Le, Rajesh K. Soni, Rebecca K. Donegan

“…During infection, Mabs can form biofilms in the lung which reduce both the ability of the immune response to clear infection and the effectiveness of antibiotic therapy. In the CF lung, heme and hemoglobin levels are increased and may provide both iron and heme to Mabs cells. …”
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Purification and expression of a novel bacteriocin, JUQZ-1, against Pseudomonas syringae pv. Actinidiae (PSA), secreted by Brevibacillus laterosporus Wq-1, isolated from the rhizos... by Yang Shuai, Yi Langbo, Yang Yi, Chen Danni, Peng Qingzhong

“…., JUQZ-1, a protein with antimicrobial properties and strong environmental tolerance, may serve as a promising alternative to antibiotics.…”
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Successful Treatment of Cisplatin Overdose with Plasma Exchange by Yasuhiro Yamada, Yoshiaki Ikuta, Kisato Nosaka, Nobutomo Miyanari, Naoko Hayashi, Hiroaki Mitsuya, Hideo Baba

“…Severe bone marrow suppression with high fever ensued on day 10, which was successfully treated with G-CSF and antibiotics. Despite moderate hearing sense reduction, he recovered without significant complications. …”
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Contribution of Medical Wards Contamination to Wound Infection among Patients Attending Ruhengeri Referral Hospital by Emmanuel Munyeshyaka, Parfait Cyuzuzo, Callixte Yadufashije, John Karemera

“…These infections are often caused by multidrug-resistant pathogens acquired via improper antibiotic use, not following infection control and prevention procedures. …”
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Natural Cyclic Peptides: Synthetic Strategies and Biomedical Applications by Devan Buchanan, Shogo Mori, Ahmed Chadli, Siva S. Panda

“…These compounds are employed in diverse roles, including antibiotics, antifungals, antiparasitics, immune modulators, and anti-inflammatory agents. …”
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Clinico- Therapeutic Study of Stevens Johnson Syndrome-Toxic Epidermal Necrolysis and Prognostic Significance of SCORTEN in Indian Patients by Neha Chetan Jangid, Ankita Nirmal Choudhary, Bela Jashwantlal Shah, Shikha Rupalkumar Shah, Harshita R Vyas, Deval Mistry

“…Results: Of 40 cases included in the study, the mean age was 36.2 ± 14 years (range 11–65) with the male: female ratio being 1.67:1. Antibiotics (37.5%) were the most common group followed by anticonvulsants (22.5%). …”
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Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome in a Child with Cystic Fibrosis by Ahmed Abushahin, Haneen Toma, Sara G. Hamad, Mutasim Abu-Hasan

“…The clinical features and the laboratory findings were consistent with the DRESS syndrome. Therefore, all antibiotics were discontinued. Progressive resolution of the symptoms was observed within two days. …”
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Refractory Chronic Diffuse Granular Myringitis with Medial Meatal Stenosis by Siew Wei Ling, Chee Chean Lim, Mohamad Fuad Shah Bin Mohd Damanhuri Shah, Philip Rajan Devesahayam

“…She was treated with multiple courses of ear drop antibiotics but had no improvement. The decision for surgical intervention was driven by the presence of a grade IV medial meatal stenosis, the potential risks associated with prolonged medical management, the distressing impact on the patient’s life, and a shared decision-making process. …”
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Streptococcus pneumoniae Coinfection in COVID-19: A Series of Three Cases by Chaitanya Pal, Paulina Przydzial, Ogechukwu Chika-Nwosuh, Shrey Shah, Pratik Patel, Nikhil Madan

“…Current literature does not favor the use of empiric, broad-spectrum antibiotics in confirmed SARS-CoV-2 infections. We present three cases of confirmed SARS-CoV-2 infections complicated by Streptococcus pneumoniae coinfection. …”
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Diagnostic Value of Mean Platelet Volume, Neutrophil-to-Lymphocyte Ratio, and Platelet to Lymphocyte Ratio for Late-Onset Neonatal Sepsis by Behzad Barekatain, Elahe Mardani, Alireza Sadeghnia, Zahra Heidari

“…However, being time-consuming, false-negative results, being affected by even a single dose of antibiotics, and expensiveness are negative aspects. …”
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Otology/Neurotology recommendations – Choosing Wisely campaign by Andrew K. Ma, Julian Nedzelski, Joseph Chen, Trung Le, Paul Mick, Jane Lea, David Morris, Margaret Aron, Sumit Agrawal, Lorne Parnes, Tamara Mijovic, Vincent Lin, Otology/Neurotology subspecialty group of the Canadian Society of Otolaryngology – Head & Neck Surgery

“…The otology/neurotology subspecialty group within the Canadian Society of Otolaryngology – Head & Neck Society developed a list of five common otologic presentations to help physicians deliver high quality effective care: (1) Don’t order specialized audiometric and vestibular testing to screen for peripheral vestibular disease, (2) Don’t perform computed tomography or blood work in the evaluation of sudden sensorineural hearing loss, (3) Don’t perform auditory brain responses (ABR) in patients with asymmetrical hearing loss, (4) Don’t prescribe oral antibiotics as first line treatment for patients with painless otorrhea associated with tympanic membrane perforation or tympanostomy tube, and (5) Don’t perform particle repositioning maneuvers without a clinical diagnosis of posterior canal benign paroxysmal positional vertigo.…”
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Health system interventions and responses to anti-microbial resistance: A scoping review of evidence from 15 African countries. by Jacob Albin Korem Alhassan, Clement Kamil Abdallah

“…The review identified four broad impacts of AMR interventions including 1. Reduction in antibiotics use, 2. Increased adherence to guidelines and protocols, 3. …”
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Kounis Syndrome Secondary to Medicine-Induced Hypersensitivity by Parackrama Karunathilake, Udaya Ralapanawa, Thilak Jayalath, Shamali Abeyagunawardena

“…He was a diagnosed patient with hypertension and dyslipidemia five years ago. After taking the antibiotics, he had developed generalized itching followed by urticaria suggesting an allergic reaction. …”
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A Prospective Open-Label Multicentre Trial on the Use of 1 G, Once Daily Ceftriaxone in Lower Respiratory Tract Infections by Donald E Low, Lionel A Mandell

“…After a minimum of three days of ceftriaxone treatment. 59 palicnls (43%) were switched to oral antibiotics. Favourable treatment outcome was found in 92.9% and treatment failure (including relapse of infection) in 7.1 % o lpalicnls. …”
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An insight into the genome-wide analysis of bacterial defense mechanisms in a uropathogenic Morganella morganii isolate from Bangladesh. by Syed Muktadir Al Sium, Barna Goswami, Sanjana Fatema Chowdhury, Showti Raheel Naser, Mihir Kanti Sarkar, Md Jobaid Faruq, Md Ahashan Habib, Shahina Akter, Tanjina Akhtar Banu, Md Murshed Hasan Sarkar, Md Salim Khan

“…The presence of biosynthetic gene clusters points to the isolate's ability to create bioactive compounds, including antibiotics. Genomic islands contained genes for metal transporters, stress proteins, toxin proteins, and genes related to horizontal gene transfer. …”
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Advances and Challenges in Pediatric Sepsis Diagnosis: Integrating Early Warning Scores and Biomarkers for Improved Prognosis by Susanna Esposito, Benedetta Mucci, Eleonora Alfieri, Angela Tinella, Nicola Principi

“…Traditional biomarkers, like procalcitonin (PCT), have improved diagnostic accuracy but are insufficient alone, often resulting in overprescription of antibiotics or delayed treatment. Combining multiple biomarkers has shown promise for early screening, though this approach can be resource-intensive and less feasible outside hospitals. …”
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Clinicoradiological Manifestations of Melioidosis with Pulmonary Involvement in a Tertiary Hospital Setup by P Prem Ananth, R Anand, R Prathipa, S Raghul Raj, N Nagarajan

“…Conclusion: Our study highlights the importance of clinical assessment, radiological findings, appropriate sampling, and culture methods in suspected melioidosis cases, especially in patients residing in endemic areas such as the coastal areas of Tamil Nadu, thereby initiating early antibiotics for improved patient outcomes.…”
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Antistaphylococcal Activity and Phytochemical Analysis of Crude Extracts of Five Medicinal Plants Used in the Center of Morocco against Dermatitis by Ikrame Zeouk, Mounyr Balouiri, Khadija Bekhti

“…Novel drugs for methicillin-resistant Staphylococcus aureus (MRSA) hospital- and community-acquired infections are needed because of the emergence of resistance against antibiotics. In this study, methanolic and aqueous extracts of Berberis hispanica, Crataegus oxyacantha, Cistus salviifolius, Ephedra altissima, and Lavandula dentata selected from an ethnopharmacological study to treat skin infections in Sefrou city (Center of Morocco) were tested for their antistaphylococcal activity against strains often involved in cutaneous disorders: two methicillin-resistant Staphylococcus aureus strains and one strain of Staphylococcus epidermidis using the well-diffusion assay, while the agar macrodilution method was used to determine the minimal inhibitory concentrations. …”
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Clinical signs and post-mortem lesions caused by clostridial enterotoxemia in rabbits by A. S. Metleva, M. N. Khakimzyanova, E. E. Sionikhin

“…Low-fiber diets result in slow cecum motility, thus, delaying transit of the intestinal contents and eventually changing the microflora. Use of antibiotics together with stress make Clostridia accumulate in the gastrointestinal tract, at the same time, reducing the number of microorganisms of other groups. …”
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