Amoxicillin/Clavulanic Acid for the Treatment of Odontogenic Infections: A Randomised Study Comparing Efficacy and Tolerability versus Clindamycin by Archiel Launch Tancawan, Maria Noemi Pato, Khamiza Zainol Abidin, A. S. Mohd Asari, Tran Xuan Thong, Puja Kochhar, Chandra Muganurmath, Monique Twynholm, Keith Barker

“…Treatment of odontogenic infections includes surgical drainage and adjunctive antibiotics. This study was designed to generate efficacy and safety data to support twice daily dosing of amoxicillin/clavulanic acid compared to clindamycin in odontogenic infections. …”
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Hantavirus Cardiopulmonary Syndrome and Diffuse Alveolar Hemorrhage in the Era of COVID-19 by Khizar Hamid, Swaminathan Perinkulam Sathyanarayanan, Touba Naim, Muhammad Hamza, Mirza Omer Mahmood Baig, Emad Abu Sitta

“…Treatment is mainly supportive; however, patients are usually treated with broad-spectrum antibiotics while workup is underway. In animal models, ribavirin and favipiravir are only effective when administered in the prodromal phase. …”
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Phage therapy in the management of respiratory and pulmonary infections: a systematic review by Patience Sarkodie-Addo, Abdul-Halim Osman, Bill Clinton Aglomasa, Eric S. Donkor

“…This menace is intensified by the alarming increase in drug resistance, which limits the availability of effective antibiotics for bacterial respiratory infections. Consequently, there is an urgent demand for alternative therapeutic options. …”
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Antimicrobial susceptibility patterns of pathogens isolated from clinical specimens at a tertiary care hospital in Bangladesh, 2020–2023 by Mohammad Kamruzzaman, Fahim Alam Nobel, Saiful Islam, Amiyo Haider, Mohammad Nasir Uddin, Mohammod Johirul Islam

“…The objective of the study was to determine the profile of bacteria and antibiotic resistance patterns of various clinical specimens at a tertiary care hospital in Mymensingh, Bangladesh from January 2020 to December 2023. …”
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Antibacterial activity and impact on keratinocyte cell growth of Cutibacterium acnes bacteriophages in a Cutibacterium acnes IA1- colonized keratinocyte model by Juan C Farfán-Esquivel, María Victoria Gutiérrez, Alejandro Ondo-Méndez, John M González, Martha J Vives-Flórez

“…Various treatments for acne can cause side effects, and it has been reported that C. acnes is resistant to prescribed antibiotics. Phage therapy has been proposed as an alternative treatment for acne, given its species-specificity to kill bacteria, its relative innocuity, and its potential to manage antibiotic-resistant pathogens. …”
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Prevalence of neonatal sepsis and associated factors among neonates admitted in the neonatal intensive care unit at Lira Regional Referral Hospital, Northern Uganda. by Brendah Katugume, JohnBaptist Muzungu, Nelson Okello, Eustes Kigongo, Deborah Andrinar Namutebi

“…Therefore, it was suggested that caregivers ensure safe newborn care, detect infections early, and use prophylactic antibiotics for high-risk babies after birth, to reduce NS. …”
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Evaluation of the Synergistic Antimicrobial Activity of Essential Oils and Cecropin A Natural Peptide on Gram-Negative Bacteria by Filippo Fratini, Chiara Pecorini, Ilaria Resci, Emma Copelotti, Francesca Paola Nocera, Basma Najar, Simone Mancini

“…In an era dominated by the phenomenon of antibiotic resistance, it is increasingly important to look for alternatives to synthetic antibiotics. …”
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Permeability-Enhancing and Protective Effect on Small Intestine of Punicic Acid in Different Forms and Their Nanoemulsions With Low Toxicity by Duan D, Xie H, Jiang J, Yang P, Guo Z, Guo X, Chen X, Yao Q

“…Dongyan Duan,1,* Hua Xie,2,* Jiayi Jiang,1 Ping Yang,1 Zhiyuan Guo,2 Xiaoqiang Guo,1 Xingyu Chen,1 Qian Yao1 1Key Laboratory of Medicinal and Edible Plants Resources Development of Sichuan Education Department, Sichuan Industrial Institute of Antibiotics, School of Pharmacy, Chengdu University, Chengdu, 610106, People’s Republic of China; 2Sichuan Provincial Institute for Drug Control and Research, Chengdu, 610000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qian Yao, School of Pharmacy, Chengdu University, Shiling Town, Longquan District, Chengdu, Sichuan Province, 610106, People’s Republic of China, Email yaoqian@cdu.edu.cnPurpose: Most absorption enhancers boost the oral absorption of drugs via increasing intestinal permeability. …”
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Alkali metal salt modulated visible photocatalytic degradation of tetracycline hydrochloride by g-C3N4: Degradation pathway, mechanism and toxicity assessment by Yujie Jiao, Sujin Lu, Ru Li, Qikai Liu, Yongxia Ma, Fei Fu, Yaqi Mao, Yang Liu

“…The frequent occurrence of tetracycline antibiotics in natural water systems poses a substantial risk to aquatic ecosystems and human health. …”
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Some of the applications level of the protection and control of mastitis in dairy cattle farms in turkey with different qualifications by Ali Rişvanlı, Nevzat Saat, Tarık Şafak, Öznur Yılmaz, Burak Fatih Yüksel, Mehmet Akif Kılınç, Halef Doğan, Murat Yüksel, Selim Kul, İbrahim Şeker

“…It was determined that the applications of teat dipping (70.4%), dry period antibiotics (72.8%), teat seal (9.5%) and mastitis vaccine (55.6%) in large farms were higher than small scale farms and It was determined that the proportion of those which do predipping and postdipping is higher than those which do not, and that iodine antiseptics are used the most in applications. …”
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Antimicrobial Resistance Patterns of Bacterial Isolates from Blood Culture among HIV/AIDS Patients at Felege Hiwot Referral Hospital, Northwest Ethiopia by Mohabaw Jemal, Teshiwal Deress, Teshome Belachew, Yesuf Adem

“…Several pathogens were resistant to greater than five antimicrobial agents, so that proper management of patients with bacteremia is needed, and a careful selection of effective antibiotics should be practiced.…”
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Antimicrobial resistance and epidemiological patterns of Streptococcus pyogenes in Türkiye by Nihan Ünübol, Nese Caglayan, Sinan Cebeci, Yeşim Beşli, Banu Sancak, Neval Yurttutan Uyar, Siavosh Salmanzadeh Ahrabi, Masoud Alebouyeh, Tanıl Kocagöz

“…This study investigated the major S. pyogenes strains responsible for infections in Türkiye and their susceptibility to beta-lactam and macrolide antibiotics. Methods: We determined the minimum inhibitory concentration using the penicillin gradient test and performed emm typing and DNA fingerprinting via pulsed-field gel electrophoresis (PFGE) to analyze the clonal spread of 92 S. pyogenes strains isolated from two hospitals in Türkiye between 2020 and 2022. …”
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Clinical management of community-acquired meningitis in adults in the UK and Ireland in 2017: a retrospective cohort study on behalf of the National Infection Trainees Collaborativ... by Amy Robinson, Kamaljit Khalsa, Arjun Chandna, John Bowen, Viva Levee, Jan Coebergh, Tom Solomon, Clive Graham, David Turner, Robert Tilley, Tim Jones, Susan Hopkins, Matthew Stevens, Daniel White, Celestine Eshiwe, Anna Goodman, Ramandeep Singh, Robert S Heyderman, Nicholas Davies, Joseph Thompson, Ed Moran, Martin Williams, Rhea O’Regan, Simon Tiberi, Jonathan Lambourne, Naomi Bulteel, Susan Larkin, Ruth McEwen, Hassan Paraiso, Aarti Shah, Martin Wiselka, Sylviane Defres, Ernest Mutengesa, Maria Krutikov, Ruth Owen, David Griffith, David Harvey, Trupti Patel, Brendan Davies, Emma Mclean, Joanna Allen, Ali Khan, Alastair Miller, Ashutosh Deshpande, Christopher Green, Lewis Jones, Mark Melzer, Fiona McGill, Amanda Fife, Nimal Wickramasinghe, Stephanie Harris, Ewan Hunter, Jayne Ellis, Benedict Rogers, Imogen Fordham, Elen Vink, Victoria Ward, Anna Smith, Andrew Rosser, Alison Muir, Ken Woodhouse, John Shone, Iain Crossingham, Ryan Jayesinghe, Eavan Muldoon, Avneet Shahi, Terry John Evans, Jeremy Wong, Eloisa MacLachlan, Amy Chue, Karishma Gokani, Katherine Ajdukiewicz, Lucinda Barrett, Frances Edwards, Adam Usher, Mairi McLeod, Su su Htwe, Grace Duane, Nicholas Wong, Jennifer Poyner, Jenni Crane, Ollie Lloyd, Emma Chisholm, Ildiko Kustos, Sam Sutton, M. Estee Torok, Isobel Ramsay, Monica Ivan, Joshua York, Jennifer Ansett, Maithili Varadarajan, Priya Sekhon, James Cruise, Shivani Kanabar, Mirella Ling, Charlotte Milne, Jayanta Sarma, Aline Wilson, Lynn Urquhart, Sahar Eldirdiri, Leila White, Jody Aberdein, Phillip Simpson, Hnin Hay Mar, Keying Tan, Eint Shwe Zin thein, Mahmoud Aziz, Anthony Cadwgan, Natasha Weston, Salman Zeb, Angela Houston, Louise Wootton, Iona Willingham, Aimee Johnson, Ashley Horsley, Eamonn Trainor, Olivier Gaillemin, Nicholas J Norton, Katie Cheung, Megan Duxbury, Emilie Bellhouse, Helena Brezovjakova, Kanitkar Tanmay, Alexsander Dawidziuk, Razan Saman, Hugh Adler, Elshadai Ejere, Yiwen Soo, Wendy Beadles, Heather Sturgeon, Brodie Cameron, David Chadwick Ben Tomlinson, Claire McGoldrick, Katie McDowell, Mpho Molosiwa, Katherine FlackAdrian Kennedy, Phoebe Cross, Fay Perry, Vithusha Inpadhas, Sarathy Selvam, Vhairi Bateman, Henry Wu, Monika Pasztor, Ajanthiha Karunakaran, Basma Soliman, Andrew Blanshard, Harish Reddy, Helen Chesterfield, Ben Schroeder, Tee Keat Teoh, Sathyavani Subbarao, Caryn RosmarinLucy Bell, Emma McGuire, Robert Serafino, Ishaan Bhide, Karanjeet Sagoo, Indran Balakrishnan, Kajal Patel, Barzo Faris, Graeme Calver, Ricky Singh, Hazel Sanghvi, Mohamed Eltayeb, Rathur Haris

“…Median time to first dose of antibiotics was 3.2 hours (IQR 1.3–9.2). 80% received empirical parenteral cephalosporins. 55% ≥60 years and 31% of immunocompromised patients received anti-Listeria antibiotics. 21% received steroids. …”
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The Impact of EGDT on Sepsis Mortality in a Single Tertiary Care Center in Lebanon by Christopher El Khuri, Gilbert Abou Dagher, Ali Chami, Ralph Bou Chebl, Tarek Amoun, Rana Bachir, Batoul Jaafar, Nesrine Rizk

“…Time to and duration of vasopressor use, choice of appropriate antibiotics, and length of ED stay were not significantly different between the two groups. …”
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Successful Treatment of Myeloid Sarcoma in an Elderly Patient with Myelodysplastic Syndrome with Reduced-Dose Azacitidine by Kazuya Sato, Nodoka Tsukada, Junki Inamura, Shigetsuna Komatsu, Keisuke Sato, Masayo Yamamoto, Motohiro Shindo, Kentaro Moriichi, Yusuke Mizukami, Mikihiro Fujiya, Yoshihiro Torimoto, Toshikatsu Okumura

“…They were refractory for antibiotics and topical tacrolimus hydrate. A tumor biopsy was performed, and the histological findings of the tumor lesion showed a proliferation of tumor cells that were positive for myeloperoxidase and CD68 and negative for CD4 and CD123. …”
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Rapid detection of carbapenem-resistant Escherichia coli and carbapenem-resistant Klebsiella pneumoniae in positive blood cultures via MALDI-TOF MS and tree-based machine learning... by Xiaobo Xu, Zhaofeng Wang, Erjie Lu, Tao Lin, Hengchao Du, Zhongfei Li, Jiahong Ma

“…This rapid identification of CREC and CRKP reduces detection time and contributes to early warning and response to potential antibiotic resistance problems in the clinic. Clinical trial number Not applicable.…”
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Age influences the circulating immune profile in pediatric sepsis by Grace Fisler, Grace Fisler, Grace Fisler, Mariana R. Brewer, Mariana R. Brewer, Mariana R. Brewer, Omar Yaipen, Clifford S. Deutschman, Clifford S. Deutschman, Clifford S. Deutschman, Matthew D. Taylor, Matthew D. Taylor, Matthew D. Taylor

“…Patients were included if they were < 21 years, admitted to the PICU, and received fluid resuscitation and antibiotics. Peripheral blood mononuclear cells were isolated from samples collected on PICU day 1.ResultsEighty patients were enrolled. …”
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Traumatic Blunt Force Renal Injury in a Diseased Horseshoe Kidney with Successful Embolization to Treat Active Bleeding: A Case Report and Literature Review by Chonlada Krutsri, Pongsasit Singhatas, Preeda Sumpritpradit, Chunlaches Chaijareenont, Wit Viseshsindh, Tharin Thampongsa, Pattawia Choikrua

“…An infected hematoma found on day 7 was successfully controlled with antibiotics. His recovery was uneventful. At the 6-month follow-up, his serum creatinine level had returned to normal. …”
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Drug-induced autoimmune-like hepatitis: A disproportionality analysis based on the FAERS database. by Wangyu Ye, Yuan Ding, Meng Li, Zhihua Tian, Shaoli Wang, Zhen Liu

“…Disproportionality analysis identified 50 drugs with strong associations to DI-ALH, with biologics, statins, antibiotics, and antiviral drugs representing the most common categories. …”
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The symbiont Wolbachia increases resistance to bifenthrin in Ectropis grisescens by regulating the host detoxification function by Tian Gao, Yong Zhang, Wanpeng Sun, Qiangkun Li, Xueyu Huang, Dian Zhi, Huabin Zi, Ruijie Ji, Yanhua Long, Chunmei Gong, Yunqiu Yang

“…Here, we initially selected appropriate antibiotic mixtures at a concentration of 300 μg ml−1. …”
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