Novel Approaches for Concurrent Irradiation in Locally Advanced Cervical Cancer: Platinum Combinations, Non-Platinum-Containing Regimens, and Molecular Targeted Agents by Giannis Mountzios, Aspasia Soultati, Dimitrios Pectasides, Meletios A. Dimopoulos, Christos A. Papadimitriou

“…In patients resistant or intolerant to platinum compounds, numerous non-platinum-containing regimens have been developed, implementing various antimetabolites, taxanes, antineoplastic antibiotics, and topoisomerase II inhibitors. More recently, molecular agents targeting critical pathways in cervical malignant transformation are being assessed in early clinical trials in combination with external-beam irradiation. …”
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Exploring Developmental Care in Neonatal Jaundice Management: A Case Report with Supporting Literature Synthesis by Esther Aduramo, Deborah T. Esan, Emmanuel Adesuyi, Opeoluwa Olabode, Elizabeth Awoniyi, Blessed Oyama, Oluwadamilare Akingbade

“…Upon admission, she required high-flow oxygen therapy for mild respiratory distress and intravenous antibiotics for suspected sepsis. Her serum bilirubin levels reached 236 µmol/L, exceeding the treatment threshold defined by the National Institute for Health and Care Excellence guidelines, leading to the initiation of phototherapy. …”
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Comparative analysis of salivary antimicrobial resistance genes in dental students: A PCR and questionnaire study. by Marwan Mansoor Mohammed, Priyadharshini Sekar, Jahida Al Jamal, Lujayn Abu Taha, Asma Bachir, Sausan Al Kawas

“…<h4>Introduction</h4>Antimicrobial resistance (AMR) is a major global healthcare challenge, with limited treatment options due to the decline in new antibiotics. The human oral cavity, home to diverse bacteria, is crucial for maintaining oral and systemic health. …”
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Bloodstream Infection Etiology among Children and Adults by Svetlana I. Kolesnichenko, Alyona V. Lavrinenko, Lyudmila L. Akhmaltdinova

“…In this study, we have investigated difference of local sepsis etiology and antibiotic susceptibility among children and adults. …”
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Exploring the role of Microbiome in Susceptibility, Treatment Response and Outcome among Tuberculosis Patients from Pakistan: study protocol for a prospective cohort study (Micro-S... by Zia Ul-Haq, Muhammad Shahzad, Simon C Andrews

“…Successful treatment of the disease requires prolonged intake (6–8 months) of multiple antibiotics with potentially detrimental consequences on the composition and functional potential of the human microbiome. …”
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Methicillin-Resistant Staphylococcus aureus: Docking-Based Virtual Screening and Molecular Dynamics Simulations to Identify Potential Penicillin-Binding Protein 2a Inhibitors from... by Motahareh Masumi, Fatemeh Noormohammadi, Fatemeh Kianisaba, Fatemeh Nouri, Mohammad Taheri, Amir Taherkhani

“…The binding affinity of SauPBP2a to beta-lactam antibiotics is low, and thus, it is necessary to discover new effective SauPBP2a inhibitors to combat mortality and morbidity in patients affected by MRSA. …”
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Sustainable utilization of bovine adipose tissue derivatives as robust antimicrobial agents against Methicillin-resistant Staphylococcus aureus by Muhammed Abdelhameed Ismael Alcici, Salma Waheed Abdelhaleem, Karima Mogahed Fahim, Neveen Mohamed Saleh, Heba Saeed Farag

“…Abstract Background The excessive use of antibiotics is a major contributor to the global issue of antimicrobial resistance (AMR), a significant threat to human and animal health. …”
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Boosting the synthesis of 3-acetamido-5-acetylfuran from N-acetyl-D-glucosamine: understanding the significant role of homogeneous Cl - by Delong Yang, Jinhang Dai, Ziting Du, Qingya Cao, Gang Chen, Ting Qi, Weilu Wang, Fukun Li

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Nano-MIP based SPR sensor for tetracycline analysis in milk sample by Monireh Bakhshpour-Yücel, Melike Küçük, Elif Tümay Özer, Bilgen Osman

“…Recent advancements in sensor technology have enabled the detection of antibiotics in food, ensuring human safety. In this study, we developed a surface plasmon resonance (SPR) sensor based on molecularly imprinted nanoparticles (MINps) for the real-time, sensitive, and in-situ detection of tetracycline (Tc). …”
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Clinical-surgical characterization of acute cholecystitis in patients treated in the General Surgery Service. Cienfuegos, 2017-2019 by Jorge Luis Estepa Pérez, Tahiluma Santana Pedraza, Jorge Luis Estepa Ramos, José Antonio Feliú Rosa

“…The variables age, sex, associated diseases, clinical manifestations, diagnostic confirmation, type of treatment, modality of surgical treatment, evolution, complications, use of antibiotics, place of admission and hospital stay were analyzed. …”
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Heme alters biofilm formation in Mycobacterium abscessus by Hadia Aftab, Jessica Samudio, Grace Wang, Lily Le, Rajesh K. Soni, Rebecca K. Donegan

“…During infection, Mabs can form biofilms in the lung which reduce both the ability of the immune response to clear infection and the effectiveness of antibiotic therapy. In the CF lung, heme and hemoglobin levels are increased and may provide both iron and heme to Mabs cells. …”
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Successful Treatment of Cisplatin Overdose with Plasma Exchange by Yasuhiro Yamada, Yoshiaki Ikuta, Kisato Nosaka, Nobutomo Miyanari, Naoko Hayashi, Hiroaki Mitsuya, Hideo Baba

“…Severe bone marrow suppression with high fever ensued on day 10, which was successfully treated with G-CSF and antibiotics. Despite moderate hearing sense reduction, he recovered without significant complications. …”
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Contribution of Medical Wards Contamination to Wound Infection among Patients Attending Ruhengeri Referral Hospital by Emmanuel Munyeshyaka, Parfait Cyuzuzo, Callixte Yadufashije, John Karemera

“…These infections are often caused by multidrug-resistant pathogens acquired via improper antibiotic use, not following infection control and prevention procedures. …”
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Natural Cyclic Peptides: Synthetic Strategies and Biomedical Applications by Devan Buchanan, Shogo Mori, Ahmed Chadli, Siva S. Panda

“…These compounds are employed in diverse roles, including antibiotics, antifungals, antiparasitics, immune modulators, and anti-inflammatory agents. …”
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Clinico- Therapeutic Study of Stevens Johnson Syndrome-Toxic Epidermal Necrolysis and Prognostic Significance of SCORTEN in Indian Patients by Neha Chetan Jangid, Ankita Nirmal Choudhary, Bela Jashwantlal Shah, Shikha Rupalkumar Shah, Harshita R Vyas, Deval Mistry

“…Results: Of 40 cases included in the study, the mean age was 36.2 ± 14 years (range 11–65) with the male: female ratio being 1.67:1. Antibiotics (37.5%) were the most common group followed by anticonvulsants (22.5%). …”
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Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome in a Child with Cystic Fibrosis by Ahmed Abushahin, Haneen Toma, Sara G. Hamad, Mutasim Abu-Hasan

“…The clinical features and the laboratory findings were consistent with the DRESS syndrome. Therefore, all antibiotics were discontinued. Progressive resolution of the symptoms was observed within two days. …”
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Refractory Chronic Diffuse Granular Myringitis with Medial Meatal Stenosis by Siew Wei Ling, Chee Chean Lim, Mohamad Fuad Shah Bin Mohd Damanhuri Shah, Philip Rajan Devesahayam

“…She was treated with multiple courses of ear drop antibiotics but had no improvement. The decision for surgical intervention was driven by the presence of a grade IV medial meatal stenosis, the potential risks associated with prolonged medical management, the distressing impact on the patient’s life, and a shared decision-making process. …”
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Streptococcus pneumoniae Coinfection in COVID-19: A Series of Three Cases by Chaitanya Pal, Paulina Przydzial, Ogechukwu Chika-Nwosuh, Shrey Shah, Pratik Patel, Nikhil Madan

“…Current literature does not favor the use of empiric, broad-spectrum antibiotics in confirmed SARS-CoV-2 infections. We present three cases of confirmed SARS-CoV-2 infections complicated by Streptococcus pneumoniae coinfection. …”
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Diagnostic Value of Mean Platelet Volume, Neutrophil-to-Lymphocyte Ratio, and Platelet to Lymphocyte Ratio for Late-Onset Neonatal Sepsis by Behzad Barekatain, Elahe Mardani, Alireza Sadeghnia, Zahra Heidari

“…However, being time-consuming, false-negative results, being affected by even a single dose of antibiotics, and expensiveness are negative aspects. …”
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Otology/Neurotology recommendations – Choosing Wisely campaign by Andrew K. Ma, Julian Nedzelski, Joseph Chen, Trung Le, Paul Mick, Jane Lea, David Morris, Margaret Aron, Sumit Agrawal, Lorne Parnes, Tamara Mijovic, Vincent Lin, Otology/Neurotology subspecialty group of the Canadian Society of Otolaryngology – Head & Neck Surgery

“…The otology/neurotology subspecialty group within the Canadian Society of Otolaryngology – Head & Neck Society developed a list of five common otologic presentations to help physicians deliver high quality effective care: (1) Don’t order specialized audiometric and vestibular testing to screen for peripheral vestibular disease, (2) Don’t perform computed tomography or blood work in the evaluation of sudden sensorineural hearing loss, (3) Don’t perform auditory brain responses (ABR) in patients with asymmetrical hearing loss, (4) Don’t prescribe oral antibiotics as first line treatment for patients with painless otorrhea associated with tympanic membrane perforation or tympanostomy tube, and (5) Don’t perform particle repositioning maneuvers without a clinical diagnosis of posterior canal benign paroxysmal positional vertigo.…”
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