Successful Treatment of High-Level Aminoglycoside-Resistant Enterococcus faecalis Bacteremia in a Preterm Infant with Ampicillin and Cefotaxime by Jennifer Tam, Santina J. Lee, Vibhuti Shah, Shaun K. Morris

“…Enterococcal bloodstream infections are usually treated with single-agent antibiotics. In persistent infections, synergistic combination therapy is often required with a beta-lactam and an aminoglycoside antibiotic. …”
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Spontaneous ureteral rupture: A rare case report and review of literature by Anass El Alaoui, MD, Abdelghani Ouraghi, MD, Hemdellah Debbe Salem, MD, Anouar El Moudane, MD, Ali Barki, MD

“…The treatment involved antibiotics and double-J stenting. This case demonstrates that spontaneous ureteral rupture should be suspected in urolothiasis patients presenting for a severe pain even if the calculus is small and the laboratory markers are normal. …”
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Suppression of the Oncogenic Transcription Factor FOXM1 by Proteasome Inhibitors by Andrei L. Gartel

“…We identified the thiazole antibiotics Siomycin A and thiostrepton as inhibitors of transcriptional activity and FOXM1 expression via proteasome inhibition. …”
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Quinazoline scaffold as a target for combating microbial resistance: Synthesis and antimicrobial profiling of quinazoline derivatives by Vishwanath Halappanavar, Sangappa Teli, Hanamant B. Sannakki, Dharyappa Teli

“…With their natural accomplishments, quinazoline derivatives have the potential to advance the development of novel antibiotics and fill the gap for potent antimicrobial drugs. …”
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Extensive Mycobacterium abscessus Pneumonia in an Immunocompetent Infant with No Underlying Lung Pathology by Morouge M. Alramadhan, James R. Murphy, Michael L. Chang

“…Treatment is complicated by frequent resistance to many antibiotics. We present a case report of a 4-month-old female infant with 2 months of cough, difficulty feeding, and failure to thrive, with extensive culture-confirmed M. abscessus pulmonary infection without identified immunodeficiency or underlying lung pathology following multidisciplinary evaluation. …”
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Hemoglobin: A Nitric-Oxide Dioxygenase by Paul R. Gardner

“…NOD inhibitors are being pursued for therapeutic applications as antibiotics and antitumor agents. Transgenic NOD-expressing plants, fish, algae, and microbes are being developed for agriculture, aquaculture, and industry.…”
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Fatal Septic Shock in a Patient with Hemophagocytic Lymphohistiocytosis Associated with an Infectious Mononucleosis by Giorgio Berlot, Ariella Tomasini, Lorenzo Zandonà, Eugenio Leonardo, Rossana Bussani, Nadia Zarrillo

“…Despite the aggressive treatment, which included antibiotics, vasopressors, IV immunoglobulins, and the use of an extracorporeal device aimed to remove mediators released both during sepsis and the cytokine storm determined by the hemophagocytic lymphohistiocytosis, the patient died. …”
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Native Aortic and Tricuspid Valve Endocarditis Complicated by Embolic ST Elevation Myocardial Infarction by Mumtaz Zaman, Richard Loynd, Anthony Donato

“…The patient underwent urgent replacement of tricuspid and aortic valves as well as 6 weeks of IV antibiotics followed by chronic antibiotic suppression.…”
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Cotrimoxazole Prophylaxis Specifically Selects for Cotrimoxazole Resistance in Streptococcus mutans and Streptococcus sobrinus with Varied Polymorphisms in the Target Genes folA an... by Buwembo William, Charles Mugisha Rwenyonyi, Göte Swedberg, Fred Kironde

“…The selection of antibiotic resistance by cotrimoxazole prophylaxis was evaluated, and we characterized the mechanism of cotrimoxazole resistance in Streptococcus mutans and Streptococcus sobrinus. …”
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Cerebrospinal fluid leak-associated ventriculitis – a case report by Amir Waheed, Faryal Amir

“…She made an uneventful recovery after 6 weeks of intravenous antibiotics. The patient had surgical repair of bony defects to prevent recurrence.This highlights a rare case of ventriculitis associated with a spontaneous CSF leak, with no existing set diagnostic criteria, and high mortality. …”
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Septic Arthritis of the Pediatric Shoulder: From Infancy to Adolescence by Justin W. Walker, William L. Hennrikus

“…All cases were treated operatively with irrigation and debridement and with antimicrobial therapy. Patients received antibiotics for an average of 6 weeks. Conclusion. Septic arthritis of the shoulder occurs in all pediatric ages. …”
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A Case of Cutaneous Leishmaniasis Presenting to the Emergency Department by Gordon A, Malik AN

“…She was admitted on suspicion of leishmaniasis, and physicians of several specialties initiated a broad laboratory workup, collected wound cultures, prescribed antibiotics, and surgically repaired the lesion. The rapid recognition of leishmaniasis allowed for the patient to begin treatment before the definitive diagnosis returned, emphasizing the importance of knowledge of worldwide diseases and their presenting features for the ED physician.Keywords: case report, rash, parasite, vector-borne disease…”
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A Rare Case of Herpes Simplex Virus-2 Hepatitis with Negative Serology by Mohanad Soliman, Olalekan Akanbi, Ihab Almagdub, Kishore Karri, Pradeep Yarra, Saad Emhmed Ali, Hanine El Haddad

“…She was initially misdiagnosed with sepsis of unclear source and treated with broad-spectrum antibiotics. Empiric acyclovir was started one week into her hospitalization despite negative serologies while awaiting HSV2 PCR leading to complete resolution of symptoms. …”
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“The Clock Is Ticking”: The Timely Management of a Painful Skin Rash in a Seventy-Year-Old Woman by Susan Thomas, Folashade Omole, Vijaykumar G. Patel, Michelle L. Nichols

“…Management consists of immediate resuscitation, early surgical debridement, and administration of broad spectrum intravenous antibiotics. We report a case of a 70 year old woman who presented with a painful erythematous rash, was admitted as a case of cellulitis, later developed worsening of symptoms and septic shock, and was diagnosed as necrotizing fasciitis.…”
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Emphysematous Cystitis: Report of an Atypical Case by Karen De Baets, Joost Baert, Luc Coene, Marc Claessens, Robert Hente, Geert Tailly

“…Treatment consists of broad-spectrum antibiotics, bladder drainage, and management of the risk factors. …”
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Ozone therapy as support in the treatment of diabetic foot ulcer. A case report by Isidro Matos Lamote, Jorge Enrique Rodríguez León, Carlos García Arencibia, Maydelin Pérez Reina

“…Drainage of the abscess, modification of insulin treatment, and debridement of the lesion were performed. In addition, antibiotics and Heberprot-P® were indicated. In the absence of satisfactory evolution, new debridement was performed, with amputation of the third and fourth toes of the left foot; the initial treatment was resumed, this time combined with local and rectal ozone therapy. …”
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An Unusual Case of Streptococcus pyogenes Causing Ruptured Aortic Mycotic Aneurysm by Ali Someili, Anjali Shroff

“…He was treated with appropriate antibiotics. To determine the source, a white blood cell scan was done, which showed increased localization within a left-sided upper mediastinum mass. …”
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Pulmonary Vein Stenosis Mimicking Nonspecific Interstitial Pneumonia by Karthika R. Linga, Andras Khoor, Jonathan A. Phelan, Isabel Mira-Avendano

“…After an initial diagnosis of pneumonia and its nonimprovement with antibiotics, a surgical lung biopsy was done and interpreted as nonspecific interstitial pneumonia (NSIP) with vascular changes consistent with pulmonary arterial hypertension. …”
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Emphysematous Cystitis Occurred in the Case Treated with Steroid for Autoimmune Hepatitis by Tateki Yoshino, Shinya Ohara, Hiroyuki Moriyama

“…On the basis of diagnosis with emphysematous cystitis, she was treated with antibiotics based on the results of blood culture and indwelling Foley catheter. …”
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Update on Peripheral Arterial Vasodilation, Ascites and Hepatorenal Syndrome in Cirrhosis by Mladen Knotek, Boris Rogachev, Robert W Schrier

“…Another complication of decompensated cirrhosis is spontaneous bacterial peritonitis, the incidence of which can be reduced by primary or secondary antibiotic prophylaxis by using orally active antibiotics.…”
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