Prevalence of Plasmid-Mediated Quinolone Resistance Determinants and OqxAB Efflux Pumps among Extended-Spectrum β-Lactamase Producing Klebsiella pneumoniae Isolated from Patients w... by Mehdi Goudarzi, Mehdi Azad, Sima Sadat Seyedjavadi

“…Given the linkage observed between resistance to quinolones and beta lactam antibiotics, therapeutic protocol with fluoroquinolones and beta lactam antibiotics should be seriously revised in Tehran hospitals.…”
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Assessing the probiotic potential of Lactococcus lactis isolated from the intestine and gill of rainbow trout (Oncorhynchus mykiss) through in vitro analysis by Lucano Billy M., Feria Manuel A., Zatan Adrian E., Toledo Odalis E., Aguilar Jorge L., Diringer Benoit M., Castañeda Arnaldo E.

“…The emergence of diseases and the indiscriminate use of antibiotics have had deleterious consequences in the aquaculture industry. …”
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A nursing and midwifery training program in Kathmandu on antimicrobial resistance and stewardship and infection prevention and control: a qualitative and quantitative outcomes and... by Jamuna Tamrakar Sayami, Rakchya Amatya, Kshitij Karki, Deepak Bajracharya, Basudha Shrestha, Sreenidhi Srinivasan, Tyler Prentiss, Anita Shallal, Marcus Zervos, Katie Latack, Linda Kaljee

“…Key outcomes were AMS and IPC knowledge, and decision-making about empirical dispensing of antibiotics. The process evaluation focused on training content, integration into practice, implementation barriers, and recommendations for dissemination. …”
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Outcome and Management of Sepsis at RozhHalat Emergency Hospital in Erbil –Kurdistan region of Iraq by Samir Qader Ahmad, Shakawan Muhamad Ismaeel, Dara Ahmed Mohammed Ahmed Mohammed, Halgurd Fathulla Ahmed

“…All patients received empirical antibiotic therapy however 46% of cases received the wrong antimicrobials. …”
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Antibacterial Potential of Honeybee Venom and <i>Monascus purpureus</i> Extracellular Metabolites Against Multidrug-Resistant Pathogenic Bacteria by Islam I. Teiba, Yasser S. A. Mazrou, Abeer H. Makhlouf, Yasser Nehela, Abdallah E. Mohamed, Ahmed M. Abbas, Islam Mamdouh, Emad H. El-Bilawy

“…Although the three bacterial strains were resistant to the antibiotic ampicillin-sulbactam (10/10 µg), both extracts exhibited superior antibacterial activity against the three bacterial strains compared to five standard antibiotics, especially RD extract, which produced the largest inhibition zone (20 ± 0.20 mm) against <i>S. aureus.…”
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Management of Necrotising Fasciitis

“…Fasciotomy and surgical debridment was done in these cases under antibiotic cover but antibiotics failed to prove as effective mode of treatment …”
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PHOTOCHEMISTRY OF FLUOROQUINOLONES: A REVIEW by Rahila Bano

“… Fluoroquinolone antibiotics are widely used in the treatment of various infectious diseases in humans and animals. …”
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Plesiomonas shigelloides Septicemia and Meningitis in a Neonate by Julian D Eason, Donlim Peacock

“…Despite prompt treatment with appropriate antibiotics, he developed endophthalmitis and lytic brain lesions.…”
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Compassionate Use of Omadacycline in a Down Syndrome Pre-Schooler With Critically Ill Atypical Pneumonia Caused by Macrolide-Resistant Mycoplasma Pneumoniae by Wu D, Xie FJ, Wang YJ, Jiang XH, Zhang GL, Zhang H, Zhu YC, Zhang Y, Tang YJ, Lin YL, Xu JX, Zhang JN, Liu BW, Kang K, Gao Y

“…The treatment achieved a favourable therapeutic effect without any related adverse events (AEs) during hospitalization and follow-up.Conclusion: In clinical practice, rapid and accurate identification of causative organisms should be a priority for prompt initiation of pathogen-targeted antibiotics, in which tNGS possesses enormous potential, particularly for difficult-to-culture MP. …”
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Dynamic analysis of the epidemiology and pathogen distribution of bronchoalveolar lavage fluid in children with severe pulmonary infection: a retrospective study by Muchun Yu, Mingchao Li, Huiqing Sun

“…This study aims to provide a reference for the rational use of antibiotics at an early stage in children with severe pulmonary infections. …”
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Severe Cutaneous Adverse Drug Reactions at a Tertiary Care Center in Saudi Arabia by Mohammed I. AlJasser

“…The majority of drugs causing AGEP were antibiotics. The mortality rate was the highest in SJS/TEN (5/11 (45.5%)), followed by DRESS (1/23 (4.4%)) and AGEP (1/7 (14.3%)). …”
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Bowel Perforation in Premature Infants with Necrotizing Enterocolitis: Risk Factors and Outcomes by Lingling Yu, Jianmei Tian, Xingli Zhao, Ping Cheng, Xiaoqian Chen, Yun Yu, Xiaochun Ding, Xueping Zhu, Zhihui Xiao

“…Moreover, the perforated NEC group had significantly longer durations of fasting and TPN usage, higher incidences of EUGR and cholestasis, longer duration of antibiotics, higher frequency of advanced antibiotics use, and poorer prognosis than the nonperforated NEC group (all P<0.05). …”
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Miliary Tuberculosis Initially Presenting as an Isolated Hepatic Abscess by Chang Won Ha, Sang Deok Shin, Myung Ji Goh, Byeong Geun Song, Wonseok Kang, Dong Hyun Sinn, Geum-Youn Gwak, Yong-Han Paik, Moon Seok Choi, Joon Hyeok Lee

“…Despite initial treatment with antibiotics for a suspected inflammatory liver abscess, his condition did not improve. …”
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Research Progress in Small-Molecule Detection Using Aptamer-Based SERS Techniques by Li Zheng, Qingdan Ye, Mengmeng Wang, Fan Sun, Qiang Chen, Xiaoping Yu, Yufeng Wang, Pei Liang

“…Small molecules, such as toxins, antibiotics, and pesticides, have significant biological effects and are harmful to both human health and the environment. …”
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Clinical Predictors of Pseudomonas aeruginosa Bacteremia in Emergency Department by Yongsoon Choi, Jin Hui Paik, Ji Hye Kim, Seung Baik Han, Areum Durey

“…Having diabetes or presenting with urinary tract infection could be clinical factors unfavorable to use of antipseudomonal antibiotics.…”
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INNOVATIONS IN THE USE OF ACIDIFIERS: MODERN SOLUTIONS FOR LIVESTOCK PRODUCTION AND INTELLECTUAL PROPERTY ASPECTS by I. Chernega, L. Fihurska, B. Iegorov, A. Makarynska, O. Tsiundyk

“…In many countries, stricter restrictions on the use of antibiotics in livestock farming are being introduced due to concerns about bacterial resistance to drugs. …”
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Prevalence of Multiple Drug-Resistant Bacteria in the Main Campus Wastewater Treatment Plant of Wolaita Sodo University, Southern Ethiopia by Chimdesa Adugna, Krishna Moorthy Sivalingam

“…Wastewater treatment plants (WWTPs) are important reservoirs for the development of drug resistance and a potential route for the dissemination of antibiotic resistance genes (ARGs) in the environment. …”
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Estimating the Economic and Clinical Value of Reducing Antimicrobial Resistance to Three Gram-negative Pathogens in Japan by Tetsuya Matsumoto, Oliver Darlington, Ryan Miller, Jason Gordon, Phil McEwan, Takahisa Ohashi, Amer Taie, Akira Yuasa

“…Despite ample availability of Gram-positive antibiotics, there is a distinct lack of agents against Gram-negative pathogens, including carbapenem-resistant Enterobacterales, which remains a real threat in Japan. …”
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Threat to fish food safety in Nigeria: Role of antimicrobial usage and resistance in aquaculture by Lukman Adegoke Agbabiaka, Favour Ogechi Onwuzuruigbo, Olatunji Abubakar Jimoh

“…Notably, 86.7 % of farmers could not quantify antibiotic use. Concerningly, 50 % respondents used antibiotics for growth promotion, while 36.7 % used it prophylactically. …”
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Irrational medicine use and its associated factors in conflict-affected areas in Mali: a cross-sectional study by Mohamed Ali Ag Ahmed, Alassane Seydou, Issa Coulibaly, Karina Kielmann, Raffaella Ravinetto

“…Overall, 68% of the assessed prescriptions included antibiotics; 58% included injectables; and 75.79% were characterized by polypharmacy, i.e. more than two medicines per prescription. …”
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