Empedobacter brevis Meningitis in a Neonate: A Very Rare Case of Neonatal Meningitis and Literature Review by Deepak Sharma, Ankur Patel, Priyanka Soni, Pradeep Sharma, Basudev Gupta

“…The sepsis screen was positive and blood culture and cerebrospinal fluid showed growth of Empedobacter brevis that was resistant to multiple antibiotics. The neonate was treated with appropriate antibiotics and was discharged successfully. …”
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Urosepsis Causing Gastric Ischemia: A Rare but Deadly Complication by Vijay Jarodiya, Chirag Kher, Sangeetha Nanthabalan, Gunjan Shah

“…The patient was treated conservatively with intermittent nasogastric tube suctioning, acid suppression therapy and broad-spectrum antibiotics. The patient improved clinically and repeat imaging and EGD showed resolution of the ischemia. …”
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The Mechanisms of Catalysis by Metallo 𝛽-Lactamases by Michael I. Page, Adriana Badarau

“…Class B 𝛽-lactamases or metallo-𝛽-lactamases (MBLs) require zinc ions to catalyse the hydrolysis of 𝛽-lactam antibiotics such as penicillins, cephalosporins, carbapenems, and cephamycins. …”
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Pancreas as an Occult Source of Recurrent Salmonella enteritidis Bacteremia in an Immunocompromised Patient by Don Bambino Geno Tai, Laxmi Upadhyay, Ruchika Jain, Robert Goldstein

“…She was treated with intravenous and oral antibiotics but still had recurrence of fevers and bacteremia. …”
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Interplay between porin deficiency, fitness, and virulence in carbapenem-non-susceptible Pseudomonas aeruginosa and Enterobacteriaceae. by Hedi Mammeri, Youssouf Sereme, Eya Toumi, Hélène Faury, David Skurnik

“…The increasing resistance of Gram-negative bacteria to last resort antibiotics, such as carbapenems, is particularly of concern as it is a significant cause of global health threat. …”
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Neglected Fournier’s Gangrene Caused by Acinetobacter baumannii: A Rare Case Report by Arif Emre, Mehmet Sertkaya, Sami Akbulut, Yakup Duman, Ilhami Taner Kale

“…Many treatment modalities including broad-spectrum antibiotics, aggressive debridement, negative pressure wound therapy, diversion colostomy, and partial-thickness skin grafts were applied to save the patient’s life.…”
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Primary Meningococcal Type C Arthritis: A Case Report and Literature Review by Maximiliano Barahona, Jaime Catalan, Yoshiro Sato, Jaime Hinzpeter

“…It has a very good response to antibiotics and arthroscopy procedure. Short-term follow-up and functional results are often good or excellent.…”
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Pouchitis unveiled: exploring clinical features, diagnosis, and cutting-edge treatments by Francesca Lusetti, Camilla Almeida Martins Helfenberger, Munique Kurtz de Mello, Natália Sousa Freitas Queiroz

“…Traditionally the mainstay treatment of acute pouchitis involves the use of antibiotics, but one-fifth of patients develop chronic pouchitis (CP), which may be dependent or resistant to antibiotics, posing significant challenges in the management of this condition. …”
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Trichophyton as a Rare Cause of Postoperative Wound Infection Resistant to Standard Empiric Antimicrobial Therapy by Sheema Gaffar, John K. Birknes, Kenji M. Cunnion

“…Multiple wound cultures consistently grew Trichophyton fungus, and his wound infection clinically improved rapidly after starting terbinafine and discontinuing antibiotics.…”
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Identification of new ClpC1-NTD binders for Mycobacterium tuberculosis drug development by Katharina Weinhäupl, Louis Meuret, Sandy Desrat, Fanny Roussy, Nelly Morellet, Sandra Beaupierre, Catherine Guillou, Carine van Heijenoort, Olga Abian, Sonia Vega, Ian Wolf, Tatos Akopian, Olga Krandor, Eric Rubin, Adrian Velazquez-Campoy, Diego Gauto, Hugo Fraga

“…Recent studies have shown that several natural product antibiotics targeting the unfoldase N-terminal domain can impair MtbClpC1 function resulting in cell death. …”
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Pola Kepekaan Bakteri Penyebab Pneumonia terhadap Antibiotika di Laboratorium Mikrobiologi RSUP Dr. M. Djamil Padang Periode Januari sampai Desember 2011 by Jaka Kurniawan, Erly ., Rima Semiarty

“…The research method used was a descriptive and retrospective review of secondary data and antibiotic sensitivity test results of 432 patients types of germs. …”
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Determinants of Deescalation Failure in Critically Ill Patients with Sepsis: A Prospective Cohort Study by Nawal Salahuddin, Lama Amer, Mini Joseph, Alya El Hazmi, Hassan Hawa, Khalid Maghrabi

“…In this prospective study of patients with sepsis/septic shock, patients were categorized into 4 groups based on antibiotic administration: no change in antibiotics, deescalation, escalation (where antibiotics were changed to those with a broader spectrum of antimicrobial coverage), or mixed changes (where both escalation to a broader spectrum of coverage and discontinuation of antibiotics were carried out). …”
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Understanding biofilm--phage interactions in cystic fibrosis patients using mathematical frameworks by Emerenini Blessing O., Hartung Doris, Reyes Grimaldo Ricardo N. G., Canner Claire, Williams Maya, Agyingi Ephraim, Osgood Robert

“…Biofilm formation in a host can be extremely problematic if left untreated, especially since antibiotics can be ineffective in treating the bacteria. …”
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Clostridium difficile Peritonitis: An Emerging Infection in Peritoneal Dialysis Patients by Saira Chaughtai, Bhavika Gandhi, Zeeshan Chaughtai, Dana Tarina, Mohammad A. Hossain, Arif Asif

“…While the peritoneal fluid culture did not grow the organism (possibly because of prior empiric broad-spectrum antibiotics use), the positive PCR on stool analysis suggested C. difficile-related peritonitis, along with the rapid clinical improvement induced by C. difficile-directed therapy (metronidazole) and discontinuation of broad-spectrum antibiotics. …”
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Antimicrobial Susceptibility Patterns of Shigella Species among Children under Five Years of Age with Diarrhea in Selected Health Centers, Addis Ababa, Ethiopia by Basha Ayele, Zeleke Mekonnen, Tesfaye Sisay Tessema, Etsehiwot Adamu, Estifanos Tsige, Getenet Beyene

“…The high levels of antibiotic resistance observed among the commonly prescribed antibiotics are alarming. …”
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Surgical antimicrobial prophylaxis among surgical patients: results from a retrospective observational study at a public hospital in Liberia by Michelle Niescierenko, John Shakpeh, Kayla Enriquez, Saned Raouf, Finda Mayah-Toto

“…Background Surgical antibiotic prophylaxis (SAP) is one of the most effective measures to prevent surgical site infections (SSIs). …”
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Metabolic Profiling by UPLC–Orbitrap–MS/MS of Liver from C57BL/6 Mice with DSS-Induced Inflammatory Bowel Disease by Zhongquan Xin, Zhenya Zhai, Hongrong Long, Fan Zhang, Xiaojun Ni, Jinping Deng, Lunzhao Yi, Baichuan Deng

“…First, a refined and translationally relevant model of DSS chronic colitis in C57BL/6 mice was established, and cecropin A and antibiotics were used as interventions. We found that the levels of tumor necrosis factor (TNF)-α, interleukin (IL)-1β, and IL-6 in the liver tissues of mice were highly increased in the context of DSS treatment but were lowered by cecropin A and antibiotics. …”
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Secondary Aorto-Colonic Fistula: A Case Report and Literature Review of a Rare Complication after EVAR by Nattawadee Wiangphoem

“…After administering intravenous (IV) antibiotics, a staged axillo-bifemoral bypass graft with aortic stent graft explantation was performed. …”
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Central Hyperthermia Treated with Bromocriptine by P. Natteru, P. George, R. Bell, P. Nattanmai, C. R. Newey

“…It typically has a rapid onset with high temperatures and marked fluctuations and responds poorly to antibiotics and antipyretics. It is also associated with worse outcomes in the brain injured patient. …”
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Case report: First reported case of spondylodiscitis caused by Gemella morbillorum in South Africa by J Pillay, N M van der Linden

“…Treatment with culture-driven antibiotics yields good results. …”
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