Human microbiome, applied to clinical practice by V. T. Ivashkin, K. V. Ivashkin

“…Besides, the increasing attention of doctors and scientists is attracted to the issue intestinal microflora changes at antibiotic treatment. Conclusion. «The Human microbiome project» is implemented within identification and characterization of the microorganisms associated to the different anatomical regions of the human body tasks of the project include the study of inand interindividual microbiome disorders and their possible effect on the human health. …”
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Flavonoid Compounds from Ethanol Extract of Sungkai Leaves (Peronema canescens. Jack) and Antibacterial Activity Test Against Staphylococcus epidermidis and Escherchia coli by Nindita Clourisa Amaris Susanto, Jammes Ardhica, Nelson, Madyawati Latief

“… The rise of antibiotic-resistant bacteria has intensified the global search for alternative antimicrobial agents, particularly from natural sources. …”
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Diagnostic Challenges of Helicobacter pylori Infection in Ethiopia: A Community-Based Cross-Sectional Study by Esayas Kebede Gudina, Hiwot Amare, Solomon Ali, Melkamu Berhane Arefayine, Dagmawi Tewolde, Million Tesfaye Eshete, Mulusew Gerbaba Jebena, Andreas Wieser, Guenter Froeschl, Markos Tesfaye, Hailemichael Desalegn, Mulatu Gashaw

“…With these methods, it will be hard to ensure adequate diagnosis and early treatment of H. pylori infection, as well as rational antibiotic use.…”
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Short-Term Effect of Continuous Subcutaneous Insulin Infusion and Multiple Daily Injection in Perioperative Patients with Type 2 Diabetes Mellitus by Wei Song, Jianxuan Wen, Jinming Zhang, Meng Luo, Yue Hu, Yu Zhang, Guanjie Fan, Ling Zhao

“…Regarding slack variables, with higher surgical levels, the CSII group was closer to the ideal state than the MDI group, which indicated in improving the average fasting blood glucose (AFBG), antibiotic use days (AUD), preoperative blood glucose control time (PBGCT), first postoperative day fasting blood glucose (FPDFBG), and postoperative hospitalization days (PHD). …”
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Challenges in Diagnosis and Management of Altered Mental Status in the Setting of Urosepsis and Hydrocephalus Secondary to an Occlusive Cyst of the Fourth Ventricle: A Case Report by Matthew Van Ligten, Miles Hudson, Jonathon J. Parker, Wayne A. Martini

“…The acute management involved empirical antibiotic therapy for associated sepsis, followed by the placement of an external ventricular drain for cerebrospinal fluid diversion and sampling, including cytology and cell counts, given the concern for tonsillar herniation with a lumbar puncture. …”
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Synthesis, antibacterial evaluation and in silico studies of novel 2-(benzo[d]thiazol-2-yl)-N-arylacetamides and their derivatives as potential DHFR inhibitors by Nadia Hanafy Metwally, Galal Hamza Elgemeie, Aya Ragab Abdelrazek, Salwa Magdy Eldaly

“…Additionally, compounds 2c and 4m showed enzyme inhibition against dihydrofolate reductase in Escherichia coli with greater potency (IC50 for 2c = 3.796 µM, IC50 for 4m = 2.442 µM) than the standard antibiotic trimethoprim (IC50 = 8.706 µM). Investigation of the physicochemical properties of the newly compounds exhibited their better ADME properties that can be developed for the discovery of new antibacterial agents. …”
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Antifungal Susceptibility and Biofilm Production of Candida spp. Isolated from Clinical Samples by Munmun B. Marak, Biranthabail Dhanashree

“…Presence of other risk factors such as diabetes mellitus, history of antibiotic use, and any urinary tract instrumentations was also recorded. …”
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Prevalence and Antimicrobial Resistance of Bacteria Isolated from Marine and Freshwater Fish in Tanzania by Esther Marijani

“…The isolates were identified by their morphological characteristics, conventional biochemical tests, and analytical profile index test kits. The antibiotic susceptibility of selected bacteria was determined by the disc diffusion method. …”
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A Combination of Coconut Fiber Suture and Tamarind Seed Gel with Dehydrated Human Amnion Membrane for Wound Surgery in Rats by Raghu Babu Pothireddy, Angeline Julius, Manu Thomas Mathai, Ganesh Lakshmanan, Beimnet Asfaw Hailemariam

“…TSP enhanced cell viability, proliferation, and migration in human skin cells and cured wounds both individually and in combination with dHAM. An antibiotic-free combination of the human amniotic membrane with intact epithelium, tamarind seed polysaccharide, and immature coconut fiber provided faster wound healing. …”
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Predictive Factors, Treatment, and Outcomes of Coagulase-Negative Staphylococcal Peritonitis in Malaysian Peritoneal Dialysis Patients: A Single-Center Study by Siew Yan Lau, Boon Cheak Bee, Hin-Seng Wong, Marhanis Salihah Omar, Norazlah Bahari

“…Patients with concomitant exit-site infection (odds ratio (OR) 0.06, 95% confidence interval (CI) 0.01 to 0.40, P<0.01) and history of recent systemic antibiotic use (OR 0.04, 95% CI 0.01 to 0.82, P=0.04) were less likely to achieve primary response. …”
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The diagnostic performance of mean neutrophil volume in neonatal sepsis: A systematic review and meta-analysis by Alpana Mishra, Pratap Kumar Jena, Santosh Kumar Panda

“…Background: There is a need for reliable diagnostic tests for early identification of sepsis to prevent neonatal mortality and antibiotic misuse. During sepsis, many immature neutrophils came into the bloodstream, altering the mean neutrophil volume (MNV) shown in the previous studies. …”
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Frequency of Different Types of Diagnostic Errors in Patients with Central Nervous System Infections: A Cross-Sectional Observational Study by HamidReza Naderi, Fereshte Sheybani, Omid Khosravi, Mehdi Jabbari Nooghabi

“…The relationship between poor clinical outcome and longer delay from the onset of illness to diagnosis, inappropriate empirical antibiotic therapy, and lower level of consciousness on admission were found to be statistically significant. …”
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Strains of a virtuoso: pacemaker infection and ventricular tachycardia in a violinist by Yuanguo Chen, Haibo Zhang, Qi Qiao, Lian Ma

“…Methods A 76-year-old male violinist with a Biotronik Evia DR dual-chamber pacemaker presented with syncope and signs of a pacemaker pocket infection three years after implantation. Despite initial antibiotic treatment, the infection persisted with slightly elevated C-reactive protein (CRP) and negative cultures. …”
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Prevalence and risk factors for childhood asthma: a systematic review and meta-analysis by Weijun Zhou, Jia Tang

“…Moreover, the identified risk factors for childhood asthma included older age, male sex, obesity, parental smoking, high education of the mother, premature birth, cesarean section, no breastfeeding, family history of asthma, rhinitis, eczema, pets, high density of road traffic, meat, margarine, fast food, paracetamol use, and antibiotic use. Conclusion Childhood asthma is common, and the prevalence of asthma is highest in Oceania, with a lower prevalence in Eurasia. …”
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Expression evaluation of exogenous and endogenous alcohol dehydrogenase genes in transgenic Arabidopsis by Haoqiang Yu, Hong Lv, Fengzhong Lu, Qingqing Yang, Huaming Duan, Wanchen Li, Fengling Fu

“…Three homozygous T3 lines with a single integration site were screened for each of the three transformed genes by antibiotic screening, polymerase chain reaction (PCR) identification, and genomic DNA resequencing. …”
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The influence of depth on the global deep-sea plasmidome by Melany Calderón-Osorno, Dorian Rojas-Villalta, Franck Lejzerowicz, Jorge Cortés, Maria Arias-Andres, Keilor Rojas-Jimenez

“…Surprisingly, relatively few antibiotic resistance genes were found in the deep-sea ecosystem, with most being found in the mesopelagic layer. …”
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A CLINICAL CASE OF HOSPITAL-ACQUIRED PNEUMONIA CAUSED BY KLEBSIELLA PNEUMONIA, DUE TO CONTACT WITH A FAMILY MEMBER by N.D. Gerasymenko, N.I. Digtiar

“…Nosocomial pneumonia is provoked by antibiotic-resistant microorganisms; in the intensive care patients, it is complicated by the re-aspiration of bacteria that accumulate above the cuff of the intubation tube. …”
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Bacterial Profile and Antimicrobial Susceptibility Pattern of the Isolates from Stethoscope, Thermometer, and Inanimate Surfaces of Mizan-Tepi University Teaching Hospital, Southwe... by Teshale Worku, Dejene Derseh, Abera Kumalo

“…The severity of infection depends on the characteristics of microorganisms with a high risk of being acquired when the environment is contaminated. Antibiotic-resistant bacteria are emerging rapidly around the globe creating a serious threat. …”
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Embolic risk management in infective endocarditis: predicting the ‘embolic roulette’ by Adela Mihaela Șerban, Diana Pepine, Andreea Inceu, Alexandra Dadarlat, Alexandru Achim

“…Therefore, future perspectives should focus on identifying high-risk profiles for EE and investigating whether early surgical intervention benefits these patients, even if they respond favourably to antibiotic therapy. This review explores current literature on echocardiographic and biomarker predictors of EE in IE, aiming to enhance clinical strategies for mitigating embolic complications and improving patient outcomes.…”
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mecA and PVL genes in methicillin-resistant Staphylococcus aureus from clinical specimens: a cross-sectional hospital based study from Nepal by Sirjana Adhikari, Supriya Sharma, Sanjib Adhikari, Sanjit Shrestha, Dwij Raj Bhatta

“…We aimed to determine the prevalence and antibiotic susceptibility pattern of MRSA isolated from patients attending a burn center and to detect mecA and PVL genes among MRSA isolates. …”
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