OMP38 of Carbapenem‐Resistant Acinetobacter Baumannii‐Mediated mtDNA Release Activates the cGAS‐STING Signaling to Induce Inflammatory Response by Yang Yang, Yuanyuan Zeng, Jianjie Zhu, Jianjun Li, Lei Gu, Lin Wei, Zeyi Liu, Jian‐an Huang

“…Abstract Carbapenem‐resistant Acinetobacter baumannii (CRAB) has become a major threat in the treatment of bacterial infection, and immunotherapy in a non‐antibiotic‐dependent manner is an effective way to overcome CRAB infection. …”
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Targeted next-generation sequencing for antimicrobial resistance detection in ventilator-associated pneumonia by Yuting Li, Yanfang Jiang, Hao Liu, Yao Fu, Junying Lu, Hongyan Li, Lulu Sheng, Dejian Gu, Dong Zhang

“…Its rapid workflow makes it ideal for managing critically ill patients, enhancing treatment precision, and reducing antibiotic misuse.…”
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A Rare Case of Pneumonia Caused by Shewanella putrefaciens by Rajshree Patel, Albin Abraham, Johnson Thomas, Wanqing Zhi, Shadab Ahmed, Janice Verley

“…On the second day of hospitalization, he was diagnosed to have pneumonia based on the clinical, radiological, and laboratory findings. Empirical antibiotic treatment with vancomycin and piperacillin/tazobactam combination was initiated. …”
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A Mysterious Gram-Positive Rods by Javzandulam Natsag, Zaw Min, Yasir Hamad, Bassel Alkhalil, Atiq Rahman, Richard Williams

“…Interestingly, serum alkaline phosphatase level fell with antibiotic treatment. Mycobacterium fortuitum is ubiquitous worldwide, being found in tap water, and soil. …”
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Coexistence of β-Lactamases in Community-Acquired Infections in a Tertiary Care Hospital in India by Shahzad Mirza, Savita Jadhav, R. N. Misra, Nikunja Kumar Das

“…Nonrepetitive clinical samples from the out-patient department (OPD) were processed for bacteriological culture and identification of Enterobacteriaceae. An antibiotic susceptibility test, screening, and phenotypic confirmation for ESBLs and carbapenemases and AmpC producers were performed to check for coexistence of these enzymes. …”
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Study on Drug Usage, Storage and Wastage among Households in Chengalpattu, Tamil Nadu, India - A Cross-Sectional Study by Nancy L, Palanivel Sundaram M, Logaraj M, Anantharaman VV, Kalaivanan R

“…Increased rates of unintentional poisoning, decreased drug efficacy, and the emergence of antibiotic resistance are just a few adverse consequences that might result from such negligence. …”
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Essential oils modulate virulence phenotypes in a multidrug-resistant pyomelanogenic Pseudomonas aeruginosa clinical isolate by Jayalekshmi Haripriyan, Christy Rose Binu, Nitasha D Menon, Muralidharan Vanuopadath, Malavika B. Hari, N Namitha, Kesiya Binoy, Anil Kumar, Bipin G. Nair, Victor Nizet, Geetha B. Kumar

“…EO treatment also resulted in a significant reduction of efflux pump activity, indicative of their effect on antibiotic sensitization. Garlic oil enhanced the permeability of the bacterial membrane, resulting in decreased survival, when combined with sub-MIC concentrations of colistin. …”
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Effect of Glycyrrhiza glabra L. on Broiler Growth Performance, Slaughter and Carcass Characteristics, Blood biochemistry, and Hematological Parameters: A Systematic Review by Esen Selim, Prete Andrea, Centoducati Gerardo, Lackner Maximilian, Palangi Valiollah, Tölü Cemil

“…Future research should concentrate on uncovering underlying mechanisms, expanding geographical diversity, and exploring interactions with other feed additives, especially in antibiotic-free diets. Despite its promise, further investigation is necessary to optimize licorice’s role in poultry production.…”
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Metagenomic insights into pathogenic bacteria and antimicrobial resistance in offshore coastal sediments – An example from Gulf waters by Nazima Habibi, Saif Uddin, Hanan Al Sarawi, Ahmad Aldhameer, Montaha Behbehani, Saja Fakhraldeen, Waleed Al-Zekri, Nasreem Abdulrazzack, Farhana Zakir, Anisha Shajan

“…Globally, indiscriminate waste discharges in marine environments are one of the key contributors to pathogenic bacteria, antibiotic resistance genes (ARGs), and mobile genetic elements (MGEs). …”
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Isolation and Identification of Methicillin-Resistant Staphylococcus aureus (MRSA) from Milk in Shire Dairy Farms, Tigray, Ethiopia by Weldemelak Girmay, Getachew Gugsa, Habtamu Taddele, Yisehak Tsegaye, Nesibu Awol, Meselu Ahmed, Aklilu Feleke

“…Antibiotic-resistant Staphylococcus aureus isolates pose a severe challenge to both veterinary and health professions and dairy cattle producers. …”
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Improving Geldanamycin Production in <i>Streptomyces geldanamycininus</i> Through UV Mutagenesis of Protoplast by Yuan Yuan, Lu Yang, Zhikai Fang, Haimin Chen, Fei Sun, Hong Jiang, Jian Zhou

“…Geldanamycin, a benzoquinone ansa antibiotic, has been extensively applied in medical, agricultural, and health research areas due to its antitumor, antifungal, herbicidal, and antiradiation effects. …”
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Granulomatous Lung Disease Requiring Mechanical Ventilation Induced by a Single Application of Oxaliplatin-Based Chemotherapy for Colorectal Cancer: A Case Report by Dane Wildner, Frank Boxberger, Axel Wein, Kerstin Wolff, Heinz Albrecht, Gudrun Männlein, Rolf Janka, Kerstin Amann, Jürgen Siebler, Werner Hohenberger, Markus F. Neurath, Richard Strauß

“…Despite high-dose empiric antibiotic and antimycotic treatment, no clinical improvement was seen. …”
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Neutropenic Sepsis in the ICU: Outcome Predictors in a Two-Phase Model and Microbiology Findings by Jan M. Kruse, Thomas Jenning, Sibylle Rademacher, Renate Arnold, Clemens A. Schmitt, Achim Jörres, Philipp Enghard, Michael Oppert

“…Ineffective initial antibiotic therapy, fungal infections, and detection of multiresistant bacteria displayed a particularly poor outcome. …”
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Antibacterial potential of celery (Apium graveolens L.) extract gel against Staphylococcus aureus by Martinus Ezra Sunarno, Anita Lidesna Shinta Amat, Arley Sadra Telussa, Prisca Deviani Pakan

“…Conventional topical therapies often lead to side effects such as contact dermatitis and pruritus, compounded by the increasing problem of antibiotic resistance. Natural ingredients like celery (Apium graveolens L.) offer promising alternatives due to their antibacterial properties and gentler effects. …”
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Uncovering the genetic basis of antiviral polyketide limocrocin biosynthesis through heterologous expression by Sofiia Melnyk, Marc Stierhof, Dmytro Bratiichuk, Franziska Fries, Rolf Müller, Yuriy Rebets, Andriy Luzhetskyy, Bohdan Ostash

“…Abstract Background Streptomyces roseochromogenes NRRL 3504 produces clorobiocin, an aminocoumarin antibiotic that inhibits DNA replication. No other natural products have been isolated from this bacterium so far, despite the presence of a rich repertoire of specialized metabolite biosynthesis gene clusters (smBGCs) within its genome. …”
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The complexities of elexacaftor/tezacaftor/ivacaftor therapeutic drug monitoring in a person with cystic fibrosis and Mycobacterium abscessus pulmonary disease by Claire Y Mou, Daniel J Henderson, Angela G Matson, Karen M Herd, David W Reid, Timothy Riddles, Ellie Johnson, Brett McWhinney, Rebecca Swenson, Andrew Burke, Ieuan E S Evans

“…Utilising National Association of Testing Authorities (NATA) accredited assays and target considerations published by the Therapeutic Goods Administration (TGA), Australia, ETI plasma concentration variability was monitored over the course of an acute admission with added complexity from an antibiotic regimen including rifabutin, a moderate cytochrome P450 3A (CYP3A) inducer, and clofazimine, a mild CYP3A inhibitor. …”
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Retrospective Use of Whole-Genome Sequencing Expands the Multicountry Outbreak Cluster of Listeria monocytogenes ST1247 by Mihkel Mäesaar, Rafael Mamede, Terje Elias, Mati Roasto

“…It was concluded that the persistent nature of the multicountry outbreak-related L. monocytogenes strain VLTRLM2013 together with stress island, virulence, and antibiotic resistance genes could potentially be the determining factors for the extensive and prolonged outbreak affecting five European Union countries. …”
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Epidemiological Study of Hospital-Acquired Bacterial Conjunctivitis in a Level III Neonatal Unit by Catarina Dias, Márcia Gonçalves, Anabela João

“…Susceptibility patterns revealed bacterial resistances to several antibiotic classes. Gentamicin remains the adequate choice for empirical treatment of HAC in our NICU. …”
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Severe Wound Infection with Photobacterium damselae ssp. damselae and Vibrio harveyi, following a Laceration Injury in Marine Environment: A Case Report and Review of the Literatur... by Jörg Hundenborn, Steffi Thurig, Mechthild Kommerell, Heike Haag, Oliver Nolte

“…Management with daily wound dressing and antibiotic therapy (ofloxacin empirically, followed by doxycycline after availability of microbiology) led in the reported case to a favorable outcome, which seems to be, however, the exception based on a review of the available literature.…”
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Treated Follicular Lymphoma, Recurrent Invasive Pneumococcal Disease, Nonresponsiveness to Vaccination, and a Unique Pneumococcus by Clare Murphy, Donald Inverarity, Claire McGoldrick, Lindsay Mitchell, Pamela Paterson, Louise Thom, Giles Edwards

“…Patient management was influenced by host predisposition to pneumococcal infection, antibiotic intolerance, and poor response to polysaccharide pneumococcal vaccine. …”
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