CLINICAL PROFILES OF FROSTBITE IN DR. SOETOMO GENERAL ACADEMIC HOSPITAL: A CASE SERIES by Thomas Eduardus Sudrajat Wahyu Nugroho, Beta Subakti Nata’atmadja

“…All received standard antibiotics and three days of hospital care. No initial surgeries were performed; instead, wound checks and rehabilitation were done as outpatients. …”
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Neonatal Bacterial Meningitis: Single Reference Center Experience and Review of Current Literature: A Retrospective Cohort Study by Alper Aykanat, Hasan Tolga Celik, Gulsen Hazirolan, Sule Yigit, Murat Yurdakok

“…CONCLUSIONS: The present study underlines high rates of culture-proven neonatal bacterial meningitis among suspected newborns despite improvements in modern health care, which raises attention to careful evaluation of these patients and early administration of properly-selected antibiotics. Our incidence rates are in keeping with studies from the developed world. …”
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Optimising the secondary use of primary care prescribing data to improve quality of care: a qualitative analysis by Robert A Verheij, Niek Klazinga, Erica Barbazza, Lotte Ramerman, Dionne Kringos

“…We anchored our investigation around three tracer prescription types: antibiotics; benzodiazepines and opioids. Descriptive and explanatory themes were derived from interview data using thematic analysis.Setting Stakeholders were sampled from across the micro (clinical), meso (organisational) and macro (policy) contexts of the Dutch primary care system.Participants The study involved 28 informants representing general practitioners (GPs), community pharmacists, regional chronic care networks (care groups), academia and research institutes, insurers, professional associations, electronic health record (EHR) vendors and national authorities.Results In the Netherlands, three main sources of data for improving prescribing in primary care are in use: clinical data in the EHRs of GP practices; pharmacy data in community pharmacy databases and claims data of insurers. …”
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Occurrence of Florfenicol and Linezolid Resistance and Emergence of optrA Gene in Campylobacter coli Isolates from Tunisian Avian Farms by Manel Gharbi, Rihab Tiss, Chadlia Hamdi, Safa Hamrouni, Abderrazak Maaroufi

“…During the last two decades, due to the irrational use of antibiotics in poultry farms, high rates of antimicrobial resistance have been globally reported in C. coli and C. jejuni isolates. …”
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Unveiling the potential of spirulina algal extract as promising antibacterial and antibiofilm agent against carbapenem-resistant Klebsiella pneumoniae: in vitro and in vivo study by Mohamed I. Selim, Tarek El-banna, Fatma Sonbol, Walaa A. Negm, Engy Elekhnawy

“…In this study, thirty carbapenem-resistant K. pneumoniae isolates were collected, identified, and then screened for their susceptibility to several antibiotics and carbapenemase production genes using PCR. …”
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Innovative epitopes in Staphylococcal Protein-A an immuno-informatics approach to combat MDR-MRSA infections by Pengjun Zhou, Pengjun Zhou, Xing Shi, Jinquan Xia, Yifei Wang, Shaowei Dong

“…BackgroundMethicillin-resistant Staphylococcus aureus (MRSA) poses a significant challenge in clinical environments due to its resistance to standard antibiotics. Staphylococcal Protein A (SpA), a crucial virulence factor of MRSA, undermines host immune responses, making it an attractive target for vaccine development. …”
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The safety and efficacy of neutral electrolyzed water solution for wound irrigation: post-market clinical follow-up study by Veronika Valdová, Vladimíra Štěpánová, Lenka Lapčíková

“…No reliable data exist regarding the time to wound closure, type of interventions, the use of antibiotics, the nature and rate of complications, or the causes of treatment failures.MethodsThis Post-Market Clinical Follow-Up (PMCF) study is a prospective, multicentric, observational, descriptive, qualitative survey among healthcare professionals that involves 237 patients with acute and chronic wounds treated with superoxide-based wound irrigation solution DebriEcaSan Alfa in real-world settings over 12 weeks, both outpatient and inpatient. …”
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A retrospective clinical study on the influencing factors of Clostridium difficile infection in elderly patients by Yang Chen, Yingjun Gong, Cui Li, Huan Li, Jia Chen, Hui Su, Xiaoming Wang, Xiaoxuan Ning

“…[Conclusion] The incidence of Clostridium difficile infection is negatively correlated with vitamin D, albumin and hemoglobin levels, and positively correlated with antibiotic use and serum creatinine level.The above indicators need to be closely monitored in elderly hospitalized patients.…”
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Marine actinobacteria metabolites: unlocking new treatments for acne vulgaris by María Clara De La Hoz-Romo, María Clara De La Hoz-Romo, Luis Díaz, Luis Díaz, Javier Gómez-León, Marynes Quintero, Luisa Villamil

“…Notably, extract Z9.216 from Kocuria sp. exhibited the highest efficacy, inhibiting S. epidermidis by 68%, S. aureus by 93%, and C. acnes by 98.7% at a concentration of 0.003 mg/mL, which was comparable to the standard antibiotics erythromycin and vancomycin, while maintaining over 90% cell viability in both HDFa and HaCaT cell lines. …”
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Chemical Constituents and Antimicrobial and Antioxidant Activities of Essential Oil from Dried Seeds of Xylopia aethiopica by Samba Fama Ndoye, Yoro Tine, Insa Seck, Lalla Aicha Ba, Seydou Ka, Ismaila Ciss, Abda Ba, Seynabou Sokhna, Moussa Ndao, Rokhaya Sylla Gueye, Nango Gaye, Abdoulaye Diop, Jean Costa, Julien Paolini, Matar Seck

“…The results indicate that consumption of X. aethiopica seeds can reduce the virulence of food-borne pathogens and their resistance to antibiotics.…”
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Screening of the Dichloromethane: Methanolic Extract of Centella asiatica for Antibacterial Activities against Salmonella typhi, Escherichia coli, Shigella sonnei, Bacillus subtili... by Berick Moturi Sieberi, George Isanda Omwenga, Rachael Kitondo Wambua, Judith Chemutai Samoei, Mathew Piero Ngugi

“…Moreover, many synthetic antibiotics are associated with side effects and progressive increase in antimicrobial resistance. …”
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Septic shock caused by emphysematous hepatitis complicated with intracranial infection by Miao Chen, Jianbo Chen, Zhengzhi Zhuang, Xiaojun He, Yue Wang, Junwen Liang, Runpei Lin, Gengxin Cai

“…The patient was treated with antibiotics and received percutaneous liver puncture drainage early and was discharged preferably in remission. …”
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Probiotic Potential of Lactobacillus Strains with Antifungal Activity Isolated from Animal Manure by Soundharrajan Ilavenil, Hyung Soo Park, Mayakrishnan Vijayakumar, Mariadhas Valan Arasu, Da Hye Kim, Sivanesan Ravikumar, Ki Choon Choi

“…The strains exhibited susceptibility against commonly used antibiotics with negative hemolytic property. Strains KCC-25, KCC-26, KCC-27, and KCC-28 showed strong antifungal activity against Aspergillus fumigatus, Penicillium chrysogenum, Penicillium roqueforti, Botrytis elliptica, and Fusarium oxysporum, respectively. …”
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Reforming the innovation system to deliver affordable medicines: a conceptual framework of pharmaceutical innovation as a complex adaptive system (forest) and theory of change by Suerie Moon, Adrian Alonso Ruiz, Marcela C. F. Vieira, Kaitlin E. Large, Iulia Slovenski

“…We found a critical mass of initiatives clustered around four areas: pandemic preparedness, neglected diseases, rare diseases and antibiotics, which we conceptualised as niches within the ecosystem. …”
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Characterization and Biofilm Inhibition of Multidrug-Resistant Acinetobacter baumannii Isolates by Poonam Yadav, Sreska Shrestha, Deepak Basyal, Ananda Tiwari, Ranjit Sah, Anil Kumar Sah, Bishal Yadav, Mark Willcox, Shyam Kumar Mishra

“…Identification and antibiotic sensitivity testing of A. baumannii isolates from clinical specimens were conducted according to the guidelines of the American Society for Microbiology. …”
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COVID-19 Infection Clinical Profile, Management, Outcome, and Antibody Response in Kidney Transplant Recipients: A Single Centre Experience by Sanjiv Jasuja, Gaurav Sagar, Anupam Bahl, Shalini Verma

“…The treatment options and used were steroids (100%), convalescent plasma (32.8%), ivermectin (58.2%), doxycycline (55.2%), remdesivir (34.3%), tocilizumab (10.4%), antibiotics (61.2%), anti-fungals (26.9%), low molecular weight heparin (45.3%), and oral anti-coagulants (26.9%). …”
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Primary Intimal (Spindle Cell) Sarcoma of the Heart: A Case Report and Review of the Literature by A. Ibrahim, A. Luk, P. Singhal, Bo Wan, A. Zavodni, R. J. Cusimano, J. Butany

“…His symptoms persisted despite a course of antibiotics for presumed diverticulitis. Laboratory values were within normal limits, though the haemoglobin was 131 g/L (normal: 140–180). …”
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Abrupt onset or exacerbation of anorexia nervosa following recent infections: a mini-review and a case report with an atypical manifestation of PANS by Lavalle Raffaele, Tournour Cristina, Rubano Serena, Delsedime Nadia, Panero Matteo, Abbate-Daga Giovanni

“…Some cases improved with antibiotics or standard psychiatric treatments, although age, symptom severity, and diagnostic markers like D8/17 varied across studies. …”
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Rare case of spontaneous renal calyx rupture due to vesicoureteral junction stone in a horseshoe kidney by Siham Oukassem, Salma Debbi, Chaima Abourak, Ola Messouad, PhD, Omar EL Aoufir, PhD, Laila Jroundi, PhD, Ali Mohammed Miko, Mamoun Diouri, Ayoub Bouhnib, Ahmed Ibrahimi, PhD

“…The patient was managed with conservative intervention, including the placement of a JJ stent, analgesics, and antibiotics. The obstructing stone was expelled during stent placement, and the patient showed a favorable clinical course thereafter. …”
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Prevalence and Antimicrobial Resistance of Escherichia coli in Chicken Meat and Edible Poultry Organs Collected from Retail Shops and Supermarkets of North Western Province in Sri... by R. A. S. S. Ranasinghe, D. A. Satharasinghe, P. S Anwarama, P. M. S. D. K. Parakatawella, L. J. P. A. P. Jayasooriya, R. M. S. B. K. Ranasinghe, R. P. V. J. Rajapakse, J. T. Y. Huat, Y. Rukayadi, Y. Nakaguchi, M. Nishibuchi, S. Radu, J. M. K. J. K. Premarathne

“…Molecular confirmation for the positive samples was done through polymerase chain reaction (PCR) using previously designed primers. An antibiotic susceptibility test was performed according to CLSI using nine antibiotics: ampicillin, amoxicillin, chloramphenicol, ceftazidime, ciprofloxacin, cephalexin, erythromycin, gentamicin, and tetracycline. …”
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