plaTform fOr Urinary tract infection diagnostiC evAluatioN (TOUCAN): a protocol for a prospective diagnostic accuracy study of point-of-care testing in patients suspected of acute... by Thomas R Fanshawe, Philip J Turner, Gail N Hayward, Margaret Glogowska, Alastair D Hay, Michael Moore, Mark Lown, Christopher C Butler, Mandy Wootton, Mark H Wilcox, Jane Freeman, Nicola Kenealy, Valerie Tate, Owain Llion, Rebecca Lowe

“…Around half of all women have a UTI in their lifetime, and a quarter experience an infection caused by organisms resistant to more than one antibiotic. Reducing inappropriate prescribing of antibiotics is a core tenet of antimicrobial stewardship. …”
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Comparative-effectiveness research of COVID-19 treatment: a rapid scoping review by Sharon E Straus, Jesmin Antony, Andrea C Tricco, Rachel Warren, Erin Macdonald, Ba Pham, Milan Patel, Fatemeh Yazdi, Amruta Radhakrishnan, Marco Ghassemi, Patricia Rios, Chantal Williams, Naveeta Ramkissoon, Matthew P Muller, Nazia Darvesh, Gordon V Cormack, Maura R Grossman, Melissa Kampman, Reid Robson

“…The most common therapeutic categories involving multiple drugs were antimalarials/antibiotics (16%), steroids/non-steroidal immunosuppressants (9%) and antimalarials/antivirals/antivirals (7%). …”
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Tannin alleviated reproductive dysfunction in pregnant ewes infected with Haemonchus contortus by Xin Li, Xin Li, Hai Xiang, Hai Xiang, Rong Liang, Rong Liang, Xinyu Han, Xinyu Han, Rongzhen Zhong, Rongzhen Zhong, Hongyu Liu, Hongyu Liu, Yi Fang, Yi Fang

“…Therefore, tannin is a suitable potential alternative to antibiotics as a feed additive.…”
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Selective dry cow therapy: Clinical field trial on prevention and cure of intramammary infections by R.E. Niemi, M. Hovinen, P.J. Rajala-Schultz

“…ABSTRACT: Intramammary antibiotic dry cow therapy (DCT) at the end of lactation is a key measure in the management and control of bovine mastitis. …”
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Factors influencing pregnancy rate following estradiol-free fixed TAI protocols in water buffaloes by Adriana Camacho de Gutiérrez, Obdulio Camacho, Steward Fernández, Yerixo González, Juan Carlos Gutiérrez-Añez

“…Furthermore, animals treated with PGF2α and antibiotics to correct abnormal uterine status showed a higher PR 86% vs 50% than animals with apparently normal uterine status. …”
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The role of artificial intelligence and machine learning in predicting and combating antimicrobial resistance by Hazrat Bilal, Muhammad Nadeem Khan, Sabir Khan, Muhammad Shafiq, Wenjie Fang, Rahat Ullah Khan, Mujeeb Ur Rahman, Xiaohui Li, Qiao-Li Lv, Bin Xu

“…In addition, AI-based clinical decision support systems in real-time guide healthcare professionals to improve prescribing of antibiotics. The review also outlines how can AI improve AMR surveillance, analyze resistance trends, and enable early outbreak identification. …”
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Evaluation of Tumour Necrosis Factor Alpha, Interleukin-2 Soluble Receptor, Nitric Oxide Metabolites, and Lipids as Inflammatory Markers in Type 2 Diabetes Mellitus

“…To restrict the influence of variables that could interfere in the interpretation of data, subjects with obesity and/or acute or chronic inflammatory disease, haemoglobinopathies, recent use of antibiotics, antiinflammatory drugs, and trauma were excluded. …”
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Perbandingan Levofloxacin dengan Ciprofloxacin Peroral dalam Menurunkan Leukosituria Sebagai Profilaksis Isk pada Kateterisasi di RSUP. Dr. M. Djamil Padang by Marwazi Sofyan, Alvarino ., Erkadius3 .

“…It is therefore a research on this efficacy between those antibiotics in lowering the incidence of leukocyturia as the measure to prevent UTI in patients with Foley catheter. …”
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Phenotypic and Complete Reference Whole Genome Sequence Analyses of Two <i>Paenibacillus</i> spp. Isolates from a Gray Wolf (<i>Canis lupus</i>) Gastrointestinal Tract by Jessika L. Bryant, Jennifer McCabe, C. Cristoph Klews, MiCayla Johnson, Ariel N. Atchley, Thomas W. Cousins, Maya Barnard-Davidson, Kristina M. Smith, Mark R. Ackermann, Michael Netherland, Nur A. Hasan, Peter A. Jordan, Evan S. Forsythe, Patrick N. Ball, Bruce S. Seal

“…The bacteria were typed as Gram-variable, and both were catalase/oxidase positive as well as sensitive to commonly used antibiotics. The bacteria digested complex carbohydrates and lipids by standard assays. …”
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Antimicrobial Stewardship in the Pediatric Emergency Department: An Observational Pre-Post Study by Erika Silvestro, Ilaria Mussinatto, Antonia Versace, Marco Denina, Giulia Pruccoli, Raffaella Marino, Giulia Mazzetti, Lorenzo Scaglione, Federico Vigna, Alessandra Macciotta, Silvia Garazzino, Claudia Bondone

“…We recorded all systemic antibiotic prescriptions for children attending our pediatric ED from January to March and from July to September 2020. …”
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Antimicrobial Resistance Surveillance of Skin and Soft Tissue Infections: Hospital-Wide Bacterial Species and Antibiograms to Inform Management at a Zonal Tertiary Hospital in Mwan... by Justine BN, Mushi MF, Silago V, Igembe Z, Muyombe J, Kishengena PP, Michael Jnr NS, Maganga MG, Massenga A, Tegete F, Massaga FA, Seni J

“…Revisiting SSTIs treatment guidelines at BMC and inclusion of SSTIs in the on-going AMR surveillance in Tanzania are recommended.Plain Language Summary: Tanzania National Action Plan on combating resistant bugs is exclusively focused on urinary tract infections and blood stream infections despite enormous impact conferred by skin and soft tissue infections.Bugs which are resistant to commonly used antibiotics were found more among patients admitted in the hospital in contrast to those attending outpatient clinics.This study highlights a pressing need to develop treatment guidelines based on generated local research-evidence to foster favorable patients’ outcomes.Keywords: skin and soft tissue infections, antimicrobial resistance, surveillance, Tanzania…”
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Purpurin suppresses Salmonella invasion of host cells by reducing the secretion of T3SS-1 effector proteins by Zhenxu Shi, Zhimin Guo, Siqi Li, Chenxiao Jiang, Jianfeng Wang, Xuming Deng, Hongtao Liu, Jiazhang Qiu

“…Typhimurium, ST) is a food-borne pathogen that can be transmitted from animals to humans and causes symptoms such as diarrhea, fever, and vomiting. While antibiotics are commonly used to treat clinical infections, the increase in drug resistance has limited their effectiveness. …”
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Efficacy and safety of anemoside B4 in canine pneumonia treatment: a prospective, randomized controlled trial by Jinzhao Ji, Jinzhao Ji, Xiaoqing Ding, Xiaoqing Ding, Chuanli Liu, Chuanli Liu, Lingling Dai, Lingling Dai, Junting Yu, Junting Yu, Linghao Li, Linghao Li, Shaobing Wan, Shaobing Wan, Yangyang Song, Junqing Zhao, Zhetong Su, Kun Jia, Kun Jia, Shoujun Li, Shoujun Li

“…Current treatment strategies primarily rely on antibiotics and corticosteroids; however, the emergence of antibiotic resistance and potential side effects from prolonged corticosteroid use limit the effectiveness of these therapies in clinical practice. …”
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Tackling antimicrobial resistance in Bangladesh: A scoping review of policy and practice in human, animal and environment sectors. by Roksana Hoque, Syed Masud Ahmed, Nahitun Naher, Mohammad Aminul Islam, Emily K Rousham, Bushra Zarin Islam, Shaikh Hassan

“…Nineteen articles on human health dealt with prescribing and/or use of antimicrobials, five on self-medication, two on non-compliance of dosage, and 10 on the sensitivity and resistance patterns of antibiotics. Four papers focused on the use of antimicrobials in food animals and seven on environmental contamination. …”
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Immunomodulatory and growth-promoting effects of Rauwolfia serpentina root powder in broiler chicks challenged with Salmonella Gallinarum by Yingyu Zhang, Hiba Rehman, Farina Khattak, Maryam Tariq, Bushra Nisar Khan, Sadia Chaman, Ayaesha Riaz, Muhammad Ovais Omer, Aqib Ali, Qamar un Nisa, Muhammad Muddassir Ali, Gulbeena Saleem

“…BackgroundAmid growing concern about antimicrobial resistance due to the irrational use of antibiotics in treating common poultry diseases, particularly Salmonella which is a foodborne pathogen in humans. …”
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Genome analysis of Bifidobacterium adolescentis and investigation of its effects on inflammation and intestinal barrier function by Bo Li, Bo Li, Haoyu Wang, Haoyu Wang, Haoyu Wang, Mengmeng Wang, Mengmeng Wang, Hewei Liang, Hewei Liang, Hewei Liang, Tongyuan Hu, Tongyuan Hu, Tongyuan Hu, Jinlong Yang, Jinlong Yang, Jinlong Yang, Shangyong Li, Xinbi You, Xinbi You, Xinbi You, Binbin Xia, Binbin Xia, Binbin Xia, Yue Yuan, Yue Yuan, Yuanqiang Zou, Yuanqiang Zou, Yinglei Miao, Yinglei Miao, Yang Sun, Yang Sun, Yang Sun

“…Genomic analysis highlighted the probiotic attributes of B. adolescentis AF91-08b2A, including resistance to antibiotics and stress, and metabolic pathways related to energy and carbohydrate metabolism, which are likely to enhance its therapeutic efficacy. …”
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Adhesive micro-liquid for efficient removal of bacterial biofilm infection by Ying Wang, Zhibang Li, Lingli Ji, Jiao Sun, Fei Gao, Ruiqing Yu, Kai Li, Wenjun Wang, Weiwei Zhao, Qi-Zhi Zhong, Shaohua Ge, Jianhua Li

“…Ionic liquids have emerged as a novel class of alternatives to antibiotics, however their inherent hydrophobicity and immiscible in water exhibits poor adhesion to bacteria and diminishes its utilization and bioavailability for infection control. …”
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Synthesis of silver Nanoparticles@Carbon Dot nanocomposites using Aegle marmelos and Euphorbia hirta: Anti vibriocidal and antioxidant properties by Gali Raman, Sirangu Joseph, D Ramachandran, Phanindra Babu Kasi, Abhinash Marukurti, Alavala Matta Reddy, P Vijaya Nirmala, V S Manikanta, R. Lohitha Kavya, K Sarojani, Anitha Kadimi, Silpa Rani Medapalli, S B Sonia Shankar, G Dinesh Ratna, K Gayathri, P Tirupathi Rao

“…In spite of the increasing Antimicrobial Resistance (AMR) in pathogenic organisms due to inappropriate usage of conventional antibiotics, there is an urgent need of alternative therapeutic antimicrobials. …”
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Occurrence of micropollutants in surface water and removal by catalytic wet peroxide oxidation enhanced filtration using polymeric membranes loaded with carbon nanotubes by Adriano S. Silva, Paulo Zadra Filho, Ana Paula Ferreira, Fernanda F. Roman, Arthur P. Baldo, Madeleine Rauhauser, Jose L. Diaz de Tuesta, Ana I. Pereira, Adrián M.T. Silva, Juliana M.T. Pietrobelli, Marzhan S. Kalmakhanova, Daniel D. Snow, Helder T. Gomes

“…The statistical analysis revealed the correlation between the pollutants, showed the oscillation in their amounts, and enabled the identification of specific pollutant groups that deserve attention for treatment, such as antibiotics and antidepressants. Moreover, an innovative catalytic wet peroxide oxidation (CWPO) intensified filtration process was investigated as a possible water treatment solution, using composite polymeric membranes loaded with carbon nanotubes (CNTs). …”
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Clostridioides difficile infection and recurrence in cancer patients (CIRCA): A multicentre, international study by Pedro Puerta-Alcalde, Jessica O'Keefe, Rachel Woolstencroft, Shipraa Kaul, Néstor López, Katie Cronin, Andrew Lim, Nicole Garcia-Pouton, Míriam Álvarez, Lynette Chee, Mateu Espasa, Ignacio Grafia, Maria Suárez-Lledó, Olivia Smibert, Carolina Garcia-Vidal, Monica A. Slavin, Michelle K. Yong, Alex Soriano, Leon J. Worth

“…Treatment predominantly involved vancomycin (81.5%), followed by metronidazole (15.0%) and fidaxomicin (9.1%). Combined antibiotics were used in 61 (11.2%) episodes. The 90-day recurrence rate was 15.6%. …”
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