A Case of Waterhouse-Friderichsen Syndrome Resulting from an Invasive Pneumococcal Infection in a Patient with a Hypoplastic Spleen by Kazumasa Emori, Nobuhiro Takeuchi, Junichi Soneda

“…After admission to the intensive care unit, extensive treatment, including polymyxin-B direct hemoperfusion and administration of methylprednisolone and broad spectrum antibiotics was immediately initiated. Despite of our efforts to save his life, the patient died six hours after the arrival. …”
Get full text

Pseudomonas mendocina bacteraemia secondary to cellulitis – a report and brief series of cases by Jorge Reis, Francisca Carmo, Inês Soares, Catarina Salvado, Mariana Fidalgo

“…He was treated with antibiotics and recovered, and was discharged home. …”
Get full text

A Comparison of the Morbidities Associated with Different Early Treatments in Tubo-Ovarian Abscess Patients by Sumanta Saha, Sujata Saha

“… OBJECTIVE: A tubo-ovarian abscess needs hospitalization and early treatment with parenteral antibiotics only or along with imaging-guided drainage. …”
Get full text

WHEAT ANTIMICROBIAL PEPTIDES by T. I. Odintsova, T. V. Korostyleva, L. L. Utkina, Ya. A. Andreev, A. A. Slavokhotova, E. A. Istomina, V. A. Pukhal’skii, T. A. Egorov

“…Plant AMP genes can be used in the engineering of pest resistance in crops and development of novel antibiotics and antimycotics. We provide a concise review of properties and gene structures of major AMP families discovered by the authors in Triticum kiharae seeds, including glycine-rich peptides, defensins, hevein-like peptides and the so-called 4-Cys peptides.…”
Get full text

Brain Metastasis Mimicking Brain Abscess in ALK-Positive Non-Small-Cell Lung Cancer by Toshio Sakatani, Hidenori Kage, Shunsaku Takayanagi, Kaoru Watanabe, Yoshihisa Hiraishi, Aya Shinozaki-Ushiku, Shota Tanaka, Tetsuo Ushiku, Nobuhito Saito, Takahide Nagase

“…However, after treatment with antibiotics, the brain lesion increased in size. Aspiration of the liquid content of the brain lesion revealed cancer cells. …”
Get full text

Recent advances in nanomaterials and their mechanisms for infected wounds management by Jianping Zhu, Fan Xia, Shuaifei Wang, Yan Guan, Fuqiang Hu, Fangying Yu

“…Wounds infected by bacteria pose a considerable challenge in the field of healthcare, particularly with the increasing prevalence of antibiotic-resistant pathogens. Traditional antibiotics often fail to achieve effective results due to limited penetration, resistance development, and inadequate local concentration at wound sites. …”
Get full text

Early Clinical Outcomes of Surgical Management following Vacuum-Assisted Closure in Poststernotomy Mediastinitis by Rafik F. Soliman, Hatem M. Soltan, Saeed O. Abdelwahed, Ibrahim M. Khalil

“…The optimal way for management is still not well established; antibiotics and frequent debridement followed by surgical closure are the mainstay for better outcomes. …”
Get full text

Erythromycin and clarithromycin modulation of growth factor-induced expression of heparanase mRNA on human lung cancer cells in vitro by Masahiro Sasaki, Takefumi Ito, Masayuki Kashima, Shin Fukui, Noriko Izumiyama, Akiko Watanabe, Masaaki Sano, Yosimasa Fujiwara, Mamoru Miura

“…In addition, we examined the effect of erythromycin (EM) and clarithromycin (CAM), which are 14-membered ring macrolide antibiotics that act as biological response modifiers, on the expression of heparanase mRNA induced by growth factors.…”
Get full text

Diversity and antibacterial potential produced by marine endophytic fungi by submerged fermentation from Buton Island, Indonesia by Isti’anah Ismi, Tarman Kustiariyah, Heri Suseno Sugeng, Nugraha Roni, Effendi Irzal, Lee Wen-Chien, Lukitaningsih Endang, Manggau Marianti A., Sari Rodiah Nurbaya

“…This study underscores the untapped potential of marine fungi for the development of new antibiotics.…”
Get full text

Polyurethanes as Biomaterials in Medicine: Advanced Applications, Infection Challenges, and Innovative Surface Modification Methods by Drożdż Kamil, Gołda-Cępa Monika, Brzychczy-Włoch Monika

“…An important challenge lies in bacterial biofilms, which complicate treatment and enhance bacterial resistance to antibiotics. To address these issues, innovative PU surface modification methods are being developed, including laser texturing, nanoparticle deposition with antibacterial properties, ion implantation, cold metal spraying, the integration of biodegradable and biocompatible components, and plasma modifications. …”
Get full text

Brucellosis Presenting with Febrile Pancytopenia: An Atypical Presentation of a Common Disease and Review of Brucellosis by Carina Chang, Bryce D. Beutler, Mark B. Ulanja, Chukwudum Uche, Milan Zdrnja

“…Treatment involves a prolonged course of multiple antibiotics; six weeks of combination therapy with aminoglycoside or rifampin and tetracycline represents the most common regimen. …”
Get full text

Does the Gut Microbiota Influence Immunity and Inflammation in Multiple Sclerosis Pathophysiology? by Monika Adamczyk-Sowa, Aldona Medrek, Paulina Madej, Wirginia Michlicka, Pawel Dobrakowski

“…The type of intestinal flora is affected by antibiotics, stress, or diet. The effects on MS through the intestinal microflora can also be achieved by antibiotic therapy and Lactobacillus. …”
Get full text

Management of Anal Fistula with Crohn's Disease by Shota Takano, Yasushi Nakamura, Kohei Tamaoka, Takafumi Yoshimoto, Yasue Irei, Yoriyuki Tsuji

“…In the past, radical surgery was performed for PFCD, but due to the risk of anal sphincter impairment, conservative therapy using antibiotics and immunosuppressive medications is currently the first treatment option. …”
Get full text

Antibacterial action of penicillin against Mycobacterium avium complex by D. Deshpande, G. Magombedze, S. Srivastava, T. Gumbo

“…INTRODUCTION: β-lactam antibiotics are promising treatments for Mycobacterium avium complex (MAC) lung disease. …”
Get full text

Streptomyces sp. MUM 195J: A Promising Probiotic for Controlling Vibrio parahaemolyticus Infection in Aquaculture by Joanna Xuan Hui Goh, Loh Teng-Hern Tan, Jodi Woan-Fei Law, Giva Kuppusamy, Janaranjani M, Kooi-Yeong Khaw, Wei Hsum Yap, Kok-Gan Chan, Vengadesh Letchumanan, Learn-Han Lee, Bey-Hing Goh

“…Its application as a feed additive elevates the survival rate of M. rosenbergii threefold, thus demonstrating efficacy at par with florfenicol antibiotic when challenged with the V. parahaemolyticus pathogen. …”
Get full text

Incidence, Antibiogram, and Comorbid Conditions of Nontyphoidal Salmonella Infections Before and After the COVID-19 Outbreak: A Retrospective, Cross-sectional Study by Kundoly V. Suseela, Aiswariya Alex, Subi Das, V. Geethalakshmi

“…No significant change in resistance to antibiotics other than ciprofloxacin was noted in the present study. …”
Get full text

A Human/Murine Chimeric Fab Antibody Neutralizes Anthrax Lethal Toxin In Vitro by Guipeng Ding, Ximin Chen, Jin Zhu, Nicholas S. Duesbery, Xunjia Cheng, Brian Cao

“…Human anthrax infection caused by exposure to Bacillus anthracis cannot always be treated by antibiotics. This is mostly because of the effect of the remaining anthrax toxin in the body. …”
Get full text

Rinosinusitis Kronis dengan Komplikasi Abses Periorbita by Effy Huriyati, Bestari Jaka Budiman, Heru Kurniawan Anwar

“…Conservative management with the provision of broad-spectrum and or combination intravenous antibiotics, decongestants and corticosteroid. The surgery management can be performed with esternal approach or functional endoscopic sinus surgery (FESS). …”
Get full text

Antibacterial properties of substituted phenethylamine-based β-lactam derivatives in oral infections by Merve Yildirim, Elif Aksakal, Taha Yasin Bayram, Eda Irmak, Harun Gun, Bunyamin Ozgeris, Arzu Gormez

“…These bacteria act as opportunistic pathogens, potentially leading to serious diseases. Moreover, antibiotic resistance is developing in these pathogenic bacteria, limiting treatment options. β-lactam antibiotics are particularly important due to their broad spectrum and selective toxicity. …”
Get full text

Green Synthesis of Iron Oxide Nanoparticles and Their Antibacterial Efficacy against Carbapenem-resistant Klebsiella pneumoniae in Bloodstream Infections by Rahul Harikumar Lathakumari, Leela Kakithakara Vajravelu, Jayaprakash Thulukanam, Vishnupriya Panneerselvam, Poornima Baskar Vimala, Dakshina Manoj Nair, Sujith Sri Surya Ravi

“…Background: Carbapenem-resistant Klebsiella pneumoniae (CRKP) poses a significant threat to global public health by rendering traditional antibiotic treatments ineffective. The increasing resistance to carbapenems and other critical antibiotics highlights an urgent need for alternative therapeutic strategies. …”
Get full text