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Functional Characteristics and Lipid Lowering Activity of Auricularia heimuer Soluble Dietary Fiber
Published 2025-01-01“…Its molecular weight, monosaccharide composition and sugar chain composition were analyzed, its water holding capacity, oil holding capacity, swelling power and other physical and chemical properties were detected, and its lipid-lowering activity in vitro was evaluated by measuring cholesterol adsorption capacity, lipase inhibition rate and cholate binding rate. The obese animal model was constructed by high fat diet (HFD) C57BL/6J mice, and treated with A. heimuer soluble dietary fiber. …”
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Migrasomes derived from human umbilical cord mesenchymal stem cells: a new therapeutic agent for ovalbumin-induced asthma in mice
Published 2025-01-01“…Results Here, we showed that inhibition of migrasomes’ production dramatically impaired the anti-inflammatory effects of hUCMSCs in OVA animals, as evidenced by a notable increase in both the infiltration of inflammatory cells and the number of epithelial goblet cells. …”
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Biochemical, Histological, and Multi-Omics Analyses Reveal the Molecular and Metabolic Mechanisms of Cold Stress Response in the Chinese Soft-Shelled Turtle (<i>Pelodiscus sinensis...
Published 2025-01-01“…The Chinese soft-shelled turtle (<i>Pelodiscus sinensis</i>), a type of warm-water reptile, is frequently chosen as the model animal to understand how organisms respond to environmental stressors. …”
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12284
Identification of Three Significant Genes Associated with Immune Cells Infiltration in Dysfunctional Adipose Tissue-Induced Insulin-Resistance of Obese Patients via Comprehensive B...
Published 2021-01-01“…Moreover, we verified the predicted hub genes by performing RT qPCR analysis in animals and human samples. Besides, the relative fraction of 22 immune cell types in adipose tissue was detected by using the deconvolution algorithm of CIBERSORT (Cell Type Identification by Estimating Relative Subsets of RNA Transcripts). …”
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Neuroprotection by chronic administration of Fluoroethylnormemantine (FENM) in mouse models of Alzheimer's disease
Published 2025-01-01“…Similar effects were observed with the daily FENM or MEM treatments. Animals infused with 0.1 mg/kg/day FENM showed prevention of Aβ25–35-induced neuroinflammation, oxidative stress and apoptosis. …”
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12287
Short-Term Activation of Peroxisome Proliferator-Activated Receptors α and γ Induces Tissue-Specific Effects on Lipid Metabolism and Fatty Acid Composition in Male Wistar Rats
Published 2019-01-01“…Male Wistar rats were randomized into three groups: a control group receiving placebo (n=8); a PPARα agonist group receiving WY-14,643 (n=6); and a PPARγ agonist group receiving rosiglitazone (n=6) for 12 days. All animals received a low-fat standard chow diet and were given a daily dose of placebo or agonist orally. …”
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Effect of K-N-Humates on Dry Matter Production and Nutrient Use Efficiency of Maize in Sarawak, Malaysia
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12292
Biodesulfurization of high-sulfur oil from the Karazhanbas field of Kazakhstan with deep eutectic solvents
Published 2025-01-01Get full text
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Associations among circulating sphingolipids, β-cell function, and risk of developing type 2 diabetes: A population-based cohort study in China.
Published 2020-12-01“…<h4>Background</h4>Animal studies suggest vital roles of sphingolipids, especially ceramides, in the pathogenesis of type 2 diabetes (T2D) via pathways involved in insulin resistance, β-cell dysfunction, and inflammation, but human studies are limited. …”
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The use of bacterial culture for Leptospirosis di- agnosis in female water buffaloes
Published 2023-11-01“…For this, 18 blood samples (16 females and two males) were extracted by puncture of the jugular vein, and these were allowed to coagulate to obtain the serum and urine samples from 2 female buffaloes, one male buffalo, and semen from 2 other animals, were collected. Additionally, two fetuses of 120 and 75 days of gestation were collected. …”
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12299
Identification of Anoikis-Related Genes in Chronic Kidney Disease Based on Bioinformatics Analysis Combined with Experimental Validation
Published 2025-01-01“…And then, we adopted the quantitative real-time PCR (RT-qPCR) assay to validate the hub genes among several CKD animal models. Furthermore, we constructed a competitive endogenous RNA (ceRNA) network for the hub genes utilizing the ENCORI and miRDB databases, while also calculating Spearman correlation coefficients. …”
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