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12241
Apoptosis induction and tumor growth suppression by hydroxyapatite nanoparticles–cisplatin combined treatment in Ehrlich solid carcinoma-bearing mice
Published 2025-01-01“…ESC group was administrated distilled water, the HAP-NPs group was treated orally with 100 mg/kg of hydroxyapatite nanoparticles, the CDDP group was administrated intraperitoneally with 5 mg/kg of Cisplatin, the HAP-NPs + CDDP group was treated with both doses of hydroxyapatite and cisplatin, the animal treatment was conducted for 20 days. Antitumor activity was assessed for two durations after 10 and 20 days. …”
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12242
Secreted LGALS3BP facilitates distant metastasis of breast cancer
Published 2025-01-01“…Compared with sensitive cells, xenograft animal experiments with MCF7/TAMR cells showed increased pulmonary metastasis, which completely disappeared in LGALS3BP-knockdown TAMR cells. …”
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12243
Mapping mycological ignorance – checklists and diversity patterns of fungi known for West Africa
Published 2020-07-01“…For several groups of animals and plants, such data are available, but for fungi, especially in tropical regions like West Africa, they are mostly missing. …”
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12244
Revealing the Neuroimaging Mechanism of Acupuncture for Poststroke Aphasia: A Systematic Review
Published 2022-01-01“…After removing the literature studies, animal studies, and case reports, 16 studies were included in the final analysis. …”
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12245
Bentonita como adsorbente de arsénico y plomo en el tracto digestivo de bovinos: estudio in vitro
Published 2024-04-01“…La proporción de bentonita recomendable como quelante de As y Pb es de 1.5%, ya que la dosis de 4.5% afectan la DIVMS y por consiguiente, la productividad animal. …”
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12246
A Neural Circuit From Paraventricular Nucleus of the Thalamus to the Nucleus Accumbens Mediates Inflammatory Pain in Mice
Published 2025-01-01“…The nucleus accumbens (NAc) plays a pivotal role in the regulation of animal behavior, and extensive research has unequivocally demonstrated its significant involvement in the occurrence and development of pain. …”
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12247
Life cycle assessment of agricultural waste recycling for sustainable environmental impact
Published 2024-01-01“…This study considered methods for recycling different agricultural waste streams, such as crop waste, animal manure, pruning materials, and by-products and subsequent uses. …”
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12248
<i>Salmonella enterica</i> serovar Schwarzengrund: Distribution, Virulence, and Antimicrobial Resistance
Published 2025-01-01“…</i> Schwarzengrund by analyzing the sequences of 2058 isolates from both human patients (N = 313) and food- and animal-associated sources, including chicken (N = 1145), turkey (N = 300), pork (N = 132), and other sources (N = 168). …”
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12249
A Risk Management Approach to Global Pandemics of Infectious Disease and Anti-Microbial Resistance
Published 2024-11-01“…The One Health approach recognizes the interconnectedness of human, animal, and environmental health, but is grounded in the biomedical model, which reduces health to the absence of disease. …”
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12250
The viability of treated piggery wastewater for reuse in agricultural irrigation
Published 2024-02-01“…Moreover, the water consumption for swine production is approximately 15 L/animal/day in southern Brazil, resulting in an unsustainable water resource demand. …”
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12251
Comparative abundance and diversity of populations of the Pseudomonas syringae and Soft Rot Pectobacteriaceae species complexes throughout the Durance River catchment from its Fren...
Published 2023-09-01“…The dynamics of human and animal pathogens in catchments have been widely studied in a large variety of contexts allowing the optimization of disease risk reduction. …”
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12252
Shift work schedules alter immune cell regulation and accelerate cognitive impairment during aging
Published 2025-01-01“…These alterations in light-dark entrainment were closely associated with dramatic impairment in the Barnes maze test for the entire group of shifted LD mice at middle age, well before cognitive decline was first observed in aged (18-22mo) animals maintained on fixed LD cycles. In conjunction with the effects of circadian dysregulation on cognition, shifted LD mice at middle age were distinguished by significant expansion of splenic B cells and B cell subtypes expressing the activation marker CD69 or inflammatory marker MHC Class II Invariant peptide (CLIP), differential increases in CLIP+, 41BB-Ligand+, and CD74 + B cells in the meningeal lymphatics, alterations in splenic T cell subtypes, and increased number and altered functional state of microglia in the dentate gyrus. …”
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12253
Stimulation of DC-CIK with PADI4 Protein Can Significantly Elevate the Therapeutic Efficiency in Esophageal Cancer
Published 2019-01-01“…Induction of CIK cells with rPADI4-stimulated DCs elevated the cell proliferation by 50.3% and the ability of CIK cells to kill ECA-109 cells by 14.7% and suppressed tumor volume by 35.1% in the animal model. Conclusion. This study demonstrates that stimulation of DC-CIK cells with PADI4 significantly suppressed tumor growth in tumor-bearing mice by promoting DC maturation, CIK cell proliferation, and cytotoxicity. …”
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12254
PET Study of Sphingosine-1-phosphate Receptor 1 Expression in Response to S. aureus Infection
Published 2021-01-01“…The specificity of [18F]TZ4877 was assessed using S1PR1-specific antagonist, NIBR-0213, and S1PR1-specific DsiRNA pretreated the animals. Immunohistochemical studies were performed to confirm the increase of S1PR1 expression in response to infection. …”
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12255
Altered functional brain connectivity in Dyt1 knock-in mouse models
Published 2025-02-01“…We also hypothesized that EMX mice would exhibit altered functional connectivity and activation patterns, supporting the idea that TorsinA dysfunction in the sensorimotor cortex alone can induce network abnormalities. In dGAG animals, we observed significantly lower functional connectivity between key sensorimotor nodes, such as the globus pallidus, somatosensory cortex, thalamus, and cerebellum. …”
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12256
Spotted fever group rickettsiae in black rats, pets, and humans in Zungarococha community, A rural area in the surroundings of Iquitos, Peru
Published 2025-01-01“…There are scarce data on rickettsial ecology in rural areas of the Peruvian Amazon basin, where seroprevalence has not been determined, and the identities of animals acting as reservoirs of these bacteria are not known. …”
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12257
QuickStroop for screening for minimal hepatic encephalopathy in patients with cirrhosis
Published 2025-03-01“…At present, there are no data on its clinical utility for MHE screening in patients in Europe, and only limited data are available regarding its comparison to the Animal Naming Test (ANT). Methods: In total, 242 patients with cirrhosis without signs of hepatic encephalopathy (HE) ≥ grade 1 and no history of overt HE were included as the development cohort. …”
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12258
Reconstruction and computer analysis of the structural and functional organization of the gene network regulating cholesterol biosynthesis in humans and the evolutionary characteri...
Published 2025-01-01“…Cholesterol is an essential structural component of cell membranes and a precursor of vitamin D, as well as steroid hormones. Humans and other animal species can absorb cholesterol from food. Cholesterol is also synthesized de novo in the cells of many tissues. …”
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12259
RNA m6A involves in regulation of oxidative stress and apoptosis may via NF-kB pathway in cadmium-induced lung cells
Published 2025-01-01“…It is also noteworthy that the results based on animals indicate that the relevant indicators and biological changes are partially similar to cell experiments. …”
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12260
A murine model of acute and prolonged abdominal sepsis, supported by intensive care, reveals time-dependent metabolic alterations in the heart
Published 2025-01-01“…For comparison, we included acutely septic mice killed at 30 h (acute sepsis, n = 15) and healthy controls animals (HC, n = 15). Cardiac tissue was collected for assessment of inflammatory and metabolic markers through gene expression, metabolomic analysis and histological assessment. …”
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