Pseudovibriamides from Pseudovibrio marine sponge bacteria promote flagellar motility via transcriptional modulation by Yitao Dai, Vitor Lourenzon, Laura P. Ióca, Dua Al-Smadi, Lydia Arnold, Ian McIntire, Roberto G. S. Berlinck, Alessandra S. Eustáquio

“…This gene cluster is also present in Pseudomonas bacteria that interact with terrestrial plants and animals. Here, we first assign functions to pseudovibriamide biosynthetic genes using reverse genetics. …”
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Assessing and evaluating human-wildlife interactions for coexistence in shared landscapes by Katia Maria Paschoaletto Micchi de Barros Ferraz, Isabella de Freitas Bento, Anna Beatriz Queiroz Di Souza, Caio da Silveira Nunes, Maria Augusta de Mendonça Guimarães, Monicque Silva Pereira, Monicque Silva Pereira, Livia Lima da Silva, Letícia Keiko Nunes de Campos, Anita Seneme Gobbi, José Caio Quadrado Alves, Loisa Fabrícia Prates Alvarez, Silvio Marchini, Ana Carla Medeiros Morato de Aquino, Vinicius Kenji de Moraes Sato, Roberta Montanheiro Paolino, Roberta Montanheiro Paolino

“…We had a total of 570 events, of which 297 were characterized as encounters and 273 as HWI. We recorded 42 animal taxa related to the events, of which 36 interacted with humans, being Nasua nasua, Cairina moschata, and Didelphis albiventris the most frequent ones. …”
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The active roles of Rhodotorula mucilaginosa ZTHY2 in regulating antioxidant capacity and immune function of Leizhou black ducks by Jiang Wu, Yingxin Hu, Namula Zhao, Wei Yang, Zhibao Chen, Zhibao Chen

“…Previous studies in mice have demonstrated that Rhodotorula mucilaginosa ZTHY2 can promote animal growth, enhance antioxidant and immune functions, and regulate intestinal flora in our laboratory. …”
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Early Changes in [18F]FDG Uptake as a Readout for PI3K/Akt/mTOR Targeted Drugs in HER-2-Positive Cancer Xenografts by Yanina Dockx, Christel Vangestel, Tim Van den Wyngaert, Manon Huizing, Sven De Bruycker, Patrick Pauwels, Steven Staelens, Sigrid Stroobants

“…CD-1 nude mice were inoculated with HER-2-overexpressing JIMT1 (trastuzumab-resistant) or SKOV3 (trastuzumab-sensitive) human cancer cells. Animals were treated with trastuzumab, everolimus (mTOR inhibitor), PIK90 (PI3K inhibitor), saline, or combination therapy. [18F]FDG scans were performed at baseline, two, and seven days after the start of the therapy. …”
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Clinical-grade extracellular vesicles derived from umbilical cord mesenchymal stromal cells: preclinical development and first-in-human intra-articular validation as therapeutics f... by Aliosha I. Figueroa-Valdés, Patricia Luz-Crawford, Yeimi Herrera-Luna, Nicolás Georges-Calderón, Cynthia García, Hugo E. Tobar, María Jesús Araya, José Matas, Darío Donoso-Meneses, Catalina de la Fuente, Jimena Cuenca, Eliseo Parra, Fernando Lillo, Cristóbal Varela, María Ignacia Cádiz, Rolando Vernal, Alexander Ortloff, Gino Nardocci, Verónica Castañeda, Catalina Adasme-Vidal, Maximiliano Kunze-Küllmer, Yessia Hidalgo, Francisco Espinoza, Maroun Khoury, Francisca Alcayaga-Miranda

“…In vitro studies evaluated the efficacy, safety, and potency of sEV; animal studies confirmed their effectiveness and safety. …”
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Large-scale production of Mansonella perstans infective larvae from engorged Culicoides milnei by Chi Anizette Kien, Chi Anizette Kien, Rene Ebai, Rene Ebai, Fanny Fri Fombad, Fanny Fri Fombad, Frederick Esofi, Frederick Esofi, Anna Ning Ntuh, Anna Ning Ntuh, Emmanuel Ouam, Emmanuel Ouam, Narcisse Victor Tchamatchoua Gandjui, Narcisse Victor Tchamatchoua Gandjui, Valerine Chawa Chunda, Valerine Chawa Chunda, Relindis Ekanya, Relindis Ekanya, Franck Noel Nietcho, Franck Noel Nietcho, Juluis Visnel Foyet, Juluis Visnel Foyet, Lucy Cho Nchang, Lucy Cho Nchang, Chefor Magha, Chefor Magha, Abdel Jelil Njouendou, Abdel Jelil Njouendou, Peter Enyong, Peter Enyong, Achim Hoerauf, Achim Hoerauf, Achim Hoerauf, Manuel Ritter, Manuel Ritter, Samuel Wanji, Samuel Wanji

“…Previous studies have developed in vitro culture systems using infective stage 3 larvae (L3), but these life stages are difficult to obtain and thus the performance of in vitro cultures is restricted and does not allow large-scale testing of drugs or even infection experiments in animal models. Therefore, we aim to establish a platform for the large-scale production of M. perstans infective larvae from engorged Culicoides milnei.MethodsCulicoides species were caught in Yangom (Yabassi Health District) in the Littoral Region of Cameroon following a blood meal on six microfilariae-positive donors with different microfilaraemic loads over one year. …”
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Restraint stress effects on glutamate signaling protein levels in the rats’ frontal cortex: Does β1 adrenoceptor activity matter? by Agnieszka Zelek-Molik, Anna Gądek-Michalska, Michał Wilczkowski, Adam Bielawski, Katarzyna Maziarz, Grzegorz Kreiner, Irena Nalepa

“…In the current study, we adopted a restraint stress (RS) model in male Wistar rats to investigate whether the blockade of β1 adrenergic receptors (β1AR) with betaxolol (BET) in stressed animals influences the body’s stress response and the expression of selected signaling proteins in the medial prefrontal cortex (mPFC).MethodsThe study was divided into two parts. …”
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Zero-BertXGB: An Empirical Technique for Abstract Classification in Systematic Reviews by Mohammad Shariful Islam, Mohammad Abu Tareq Rony, Md Rasel Hossain, Samah Alshathri, Walid El-Shafai

“…Five diverse datasets are utilized: Aceves-Martins (2021), comprising 1,258 excluded and 230 included abstracts on the utilization of animal models in depressive behaviour studies; Bannach-Brown (2016), with 896 excluded and 73 included abstracts focusing on the methodological rigour of environmental health systematic reviews; Meijboom (2021), containing 599 excluded and 32 included abstracts on the retransitioning of Etanercept in rheumatic disease patients; Menon (2022), with 896 excluded and 73 included abstracts on environmental health reviews; and a custom Clinical Review Paper Abstract (CRPA) dataset, featuring 500 excluded and 50 included abstracts. …”
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Green tea silver nanoparticles improve physiological motor and cognitive function in BALB/c mice during inflammation by Herbert Izo, Ninsiima, Ejike, Daniel Eze, Kenneth, Ssekatawa, Halima, Nalugo, Caroline, Asekenye, David, Onanyang, Edson Ireeta, Munanura, Moses, Ariong, Kevin, Matama, Gerald, Zirintunda, Ngala Elvis, Mbiydzenyuy, Fred, Ssempijja, Adam Moyosore, Afodun, Ibe Michael, Usman, Oscar Hilary, Asiimwe, Julius, Tibyangye, Keneth Iceland, Kasozi

“…Acute inflam- mation was induced in groups I–V of the experimental rodents by injecting 0.5 ml/kg of fresh egg albumin on the subplantar surface of the right hind paw and animals were monitored for 36 h. Group I–III were administered 100%, 10%, 1% green tea nanoparticles extract while group IV was given diclofenac. …”
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Characterization of Myf6 and association with growth traits in swimming crab (Portunus trituberculatus) by Baohua Duan, Weibiao Liu, Chen Zhang, Tongxu Kang, Haifu Wan, Shumei Mu, Yueqiang Guan, Zejian Li, Yang Tian, Yuqin Ren, Xianjiang Kang

“…Abstract Background Myogenic factor 6 (Myf6) plays an important role in muscle growth and differentiation. In aquatic animals and livestock, Myf6 contributes to improving meat quality and strengthening the accumulation of muscle flavor substances. …”
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GATA1-mediated macrophage polarization via TrkB/cGMP–PKG signaling pathway to promote the development of preeclampsia by Wushan Li, Fei Hou, Di Cheng, Fengchun Gao, Jin Wang, Baoxia Cui

“…Transcriptomic sequencing, bioinformatics analysis, animal experiments, and clinical sample collection were conducted to validate the role of GATA1 in PE. …”
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Synthesis and characterization of innovative GA@Ag-CuO nanocomposite with potent antimicrobial and anticancer properties by Amr H. Hashem, Mostafa A. Abdel-Maksoud, Sabiha Fatima, Saeedah M. Almutairi, Mohamed A. Ghorab, Ahmed I. El-Batal, Gharieb S. El-Sayyad

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Fractional Factorial Design and Desirability Function-Based Approach in Spice Paprika Processing Technology to Improve Extractable Colour Stability by Arnold Koncsek, Lajos Szokol, Vivien Krizsa, Hussein G. Daood, Lajos Helyes, Antal Véha, Balázs Szabó P.

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A MALDI-ToF mass spectrometry database for identification and classification of highly pathogenic bacteria by Peter Lasch, Wolfgang Beyer, Alejandra Bosch, Rainer Borriss, Michal Drevinek, Susann Dupke, Monika Ehling-Schulz, Xuewen Gao, Roland Grunow, Daniela Jacob, Silke R. Klee, Armand Paauw, Jörg Rau, Andy Schneider, Holger C. Scholz, Maren Stämmler, Le Thi Thanh Tam, Herbert Tomaso, Guido Werner, Joerg Doellinger

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Metabolomics Biomarkers in Prediction of Sudden Infant Death Syndrome: The Role of Short Chain Fatty Acids by Maria Aslam, Omer Riaz, Jawaria Aslam, Dost Muhammad Khan, Mustafa Hameed, Muhammad Suleman, Rizwan Shahid, Turke Althobaiti, Naeem Ramzan

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Low dose DNA methyltransferase inhibitors potentiate PARP inhibitors in homologous recombination repair deficient tumors by Romain Pacaud, Scott Thomas, Sibapriya Chaudhuri, Ann Lazar, Luika A. Timmerman, Pamela N. Munster

“…In contrast, the parental MDA-MB-231 cells and other HRR proficient cell lines produced smaller cell populations with short term treatment, but with much less cumulative DNA damage, and minimal cell death. In animal studies, our BRCA-engineered hypomorphs and several independent PDX models with clinically relevant BRCA mutations were acutely more vulnerable to this drug combination. …”
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Polyploidization-driven transcriptomic dynamics in Medicago sativa neotetraploids: mRNA, smRNA and allele-specific gene expression by D. F. Santoro, G. Marconi, S. Capomaccio, M. Bocchini, A. W. Anderson, A. Finotti, M. Confalonieri, E. Albertini, D. Rosellini

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Oral Supplementation with Three Vegetable Oils Differing in Fatty Acid Composition Alleviates High-Fat Diet-Induced Obesity in Mice by Regulating Inflammation and Lipid Metabolism by Waleed Aldamarany, Huang Taocui, Deng Liling, Yang Wanfu, Geng Zhong

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Advantages and Disadvantages of Partial High Pressure Homogenisation of Milk in Relation to Full-Stream Homogenisation by Katarzyna Ambroziak, Katarzyna Kiełczewska, Dorota Mickiewicz, Aneta Dąbrowska

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A genogeographic study of the Kyrgyz mountain merino via microsatellite markers by A. В. Bekturov, Zh. T. Isakova, V. N. Kipen, T. Dzh. Chortonbaev, S. B. Mukeeva, S. K. Osmonaliev, К. A. Aitbaev

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