The association between recent stressful life events and brain structure: a UK Biobank longitudinal MRI study by Cheryl R.Z. See, Annabel X. Tan, Lucia R. Valmaggia, Matthew J. Kempton

“…Abstract Background Recent stressful life events (SLEs) are an established risk factor for a range of psychiatric disorders. Animal studies have shown evidence of gray matter (GM) reductions associated with stress, and previous work has found similar associations in humans. …”
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Evaluation of tick salivary and midgut extracellular vesicles as anti-tick vaccines in White-tailed deer (Odocoileus virginianus) by Julia Gonzalez, Cristina Harvey, Cárita de Souza Ribeiro-Silva, Brenda Leal-Galvan, Kelly A. Persinger, Pia U. Olafson, Tammi L. Johnson, Adela Oliva Chavez

“…No negative effects were observed in nymphs, but on-host mortality of female A. americanum was significantly higher in vaccinated animals. No effects were observed on reproductive parameters. …”
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Mapping of Minimal Motifs of B-Cell Epitopes on Human Zona Pellucida Glycoprotein-3 by Wan-Xiang Xu, Ya-Ping He, Jian Wang, Hai-Ping Tang, Hui-Juan Shi, Xiao-Xi Sun, Chao-Neng Ji, Shao-Hua Gu, Yi Xie

“…Furthermore, the antigenicity of two peptides for hZP3172–187 and hZP3301–315 and specificity of the antibody response to these peptides were also evaluated, which produced high-titer antibodies in immunized animals that were capable of reacting to ZP on human oocytes, r-hZP3b177–348 protein, as well as r-hZP3172–190, r-hZP3303–310, and r-hZP3313–320 epitope peptides fused with truncated GST188 protein.…”
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Inflammatory-Driven Angiogenesis in Bone Augmentation with Bovine Hydroxyapatite, B-Tricalcium Phosphate, and Bioglasses: A Comparative Study by Vlad M. Anghelescu, Ioana Neculae, Octavian Dincă, Cristian Vlădan, Claudiu Socoliuc, Mirela Cioplea, Luciana Nichita, Cristiana Popp, Sabina Zurac, Alexandru Bucur

“…The study was performed in animal experimental model on the standardized monocortical defects in the tibia of 20 New Zealand rabbits. …”
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Notch Signaling Pathway Is Involved in bFGF-Induced Corneal Lymphangiogenesis and Hemangiogenesis by Fang Xie, Xue Zhang, Wenting Luo, Hongyan Ge, Dawei Sun, Ping Liu

“…Corneal hemangiogenesis reached its peak on day 7 after bFGF implantation, and corneal lymphangiogenesis was significantly higher on day 7 and 14, compared with PBS. mRNA and protein expression of VEGF-A, Dll4, and Notch1 were higher in bFGF-induced animal models compared with controls. Corneal hemangiogenesis and lymphangiogenesis decreased after 7 days of ranibizumab or dexamethasone treatment. …”
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Peripheral nerve injury induces dystonia-like movements and dysregulation in the energy metabolism: A multi-omics descriptive study in Thap1+/− mice by Colette Reinhold, Susanne Knorr, Rhonda L. McFleder, Lisa Harder-Rauschenberger, Tom Gräfenhan, Andreas Schlosser, Michael Sendtner, Jens Volkmann, Chi Wang Ip

“…Multi-omic analysis of the cerebellum, striatum and cortex in nerve-injured Thap1+/− mice revealed differences that are indicative of an altered energy metabolism compared to naive Thap1+/− and nerve-injured wt animals. These findings suggest that aberrant energy metabolism in brain regions relevant to dystonia may underlie the dystonic phenotype observed in nerve injured Thap1+/− mice.…”
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Proximal tubule-on-chip as a model for predicting cation transport and drug transporter dynamics by Isy Petit, Quentin Faucher, Jean-Sébastien Bernard, Perrine Giunchi, Antoine Humeau, François-Ludovic Sauvage, Pierre Marquet, Nicolas Védrenne, Florent Di Meo

“…However, pharmacological research suffers from poor reproducibility across clinical, animal, and experimental models. Predictivity can be improved by using Organs-on-Chips, which are more physiological, human-oriented, micro-engineered devices that include microfluidics. …”
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Deciphering sepsis: transforming diagnosis and treatment through systems immunology by Robert E. W. Hancock, Andy An, Claudia C. dos Santos, Amy H. Y. Lee

“…Achieving this transformation will require addressing barriers to systems immunology research, including its cost and resource-intensiveness, the relatively low volume of available data, and lack of suitable animal models; it will also require a change in the mindset of healthcare providers toward precision approaches. …”
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Temporal trends of community and climate changes in the anthropocene: 21-year dynamics of four major functional groups in a rocky intertidal habitat along the Pacific coast of Japa... by Hiroki Sato, Ken Ishida, Takashi Noda

“…Here, we analyzed 21 years of abundance data at the functional-group and species levels on a regional scale for four major functional groups (benthic algae, sessile animals, herbivorous benthos, and carnivorous benthos) in a rocky intertidal habitat along the northeastern Pacific coast of Japan. …”
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Fatal disseminated infection in a cat from Madrid, Spain by Llibertat Real, Alberto Barneto, Nekane Kortabarria, Gorka Aduriz

“…Case summary Toxoplasma gondii is a globally distributed apicomplexan protozoan infecting all warm-blooded animals. Cats are the definitive host, susceptible to clinical disease. …”
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A CRISPR/Cas12a electrochemical biosensing to detect pig mtDNA D-loop for ensuring food authenticity by Muhammad Ihda H.L. Zein, Clianta Yudin Kharismasari, Ari Hardianto, Salma Nur Zakiyyah, Riezki Amalia, Mehmet Ozsoz, Mara Mirasoli, Irkham, Yeni Wahyuni Hartati

“…Its robustness makes it particularly suitable for ensuring the authenticity of animal-derived food products susceptible to counterfeiting.…”
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Bacillus Calmette-Guerin (BCG) infections following intravesical BCG immunotherapy: a systematic review protocol by Roberta Monardo, Sana Arif, Aparna Rege, Erin Simon, Leila Ledbetter, Arthur W. Baker, Jason Stout, Manuela Carugati

“…No temporal, geographic, or demographic limitations will be applied. Animal studies will be excluded. Gray literature, editorials, and comments will be excluded. …”
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Evaluation of Sleep Disorders in the Elderly with Vestibular Vertigo by Zahra Hosseini Dastgerdi, Nasrin Gohari, Mobina Mehrabifard, Hasti Seifi, Bahare Khavarghazalani

“…Evidence from human and animal studies suggests a link between sleep disorders and vertigo. …”
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The Long Noncoding RNA LOXL1-AS1 Promotes the Proliferation, Migration, and Invasion in Hepatocellular Carcinoma by Jiang Liu, Chengtong Zhai, Degan Liu, Jianhua Liu

“…In addition, in the Hep-G2 cell line, LOXL1-AS1 downregulation significantly inhibited cell proliferation in the light of the MTT and colony formation assays in vitro, which was consistent with animal experiment in vivo. What is more, cell migration was also inhibited in vitro in Matrigel Transwell Assay by LOXL1-AS1 knockdown, which might be partly attributed to the reduction of MMP-2 and MMP-9 protein expressions. …”
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Prevalence of gastrointestinal nematode parasites of dogs and associated risk factors in Gondar town, Northwest Ethiopia by Tsedalu Yirsa, Amare Bihone, Getenew Teshager, Yimer Muktar, Abebe Berihun

“…Regrettably, numerous dog owners do not give priority to managing their pets' health, often ignoring treatment unless the animal is already ill. Thus, a cross-sectional study was conducted from December 2022 to April 2023 in Gondar town to determine the prevalence of gastrointestinal nematode parasites in dogs and their associated risk factors. …”
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Evaluation of radiation therapy on grafted and non-grafted defects: an experimental rat model by Milena Suemi IRIE, Isabella Neme Ribeiro dos REIS, Luiz Gustavo Gonzáles OSUNA, Guilherme José Pimentel Lopes de OLIVEIRA, Rubens SPIN-NETO, Priscilla Barbosa Ferreira SOARES

“…The right femur defect was filled with blood clot (group “Clot”) and the left femur defect by deproteinized bovine bone mineral graft (group “Xenograft”). The animals were divided into two groups: without radiation therapy (nRTX) and with radiation therapy (RTX). …”
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Upregulation of Cardiac IL-10 and Downregulation of IFN-γ in Balb/c IL-4−/− in Acute Chagasic Myocarditis due to Colombian Strain of Trypanosoma cruzi by Marcos Vinicius da Silva, Vera Lúcia de Almeida, Wendyson Duarte de Oliveira, Natália Carasek Matos Cascudo, Pollyana Guimarães de Oliveira, Crislaine Aparecida da Silva, Aline Cristina Souza da Silva, Maria Luíza Gonçalves dos Reis Monteiro, Rosana Rosa Miranda Correa, Milton Adriano Pelli Oliveira, Ruy de Sousa Lino-Júnior, Mara Rúbia Nunes Celes, Juliana Reis Machado

“…After 21 days of infection, animals were euthanized and the blood, spleen, and heart were collected. …”
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Cytokine and Chemokine Responses of Peripheral Blood Mononuclear Cells from Dogs Infected with <i>Mycobacterium bovis</i> by Tyler Morrison, Danielle A. Gunn-Moore, Jayne C. Hope, Conor O’Halloran

“…Mycobacterial infections are an important emerging zoonosis in companion animals for which diagnostic options remain imperfect, and the canine immunological response to these infections has been poorly investigated. …”
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Effect of structured lipids as dietary supplements on the fatty acid profile, carcass yield, blood chemistry, and abdominal fat deposition of female broilers by Hongzeng Ai, Yee-Ying Lee, Yuxia Lu, Chin Ping Tan, Oi Ming Lai, Aijun Li, Yufei Zhang, Yong Wang, Zhen Zhang

“…No significant differences have been observed in carcass yield results of the POL and H-AMD groups. Compared with animal-derived oils such as lard which are also rich in saturated fatty acids at the sn-2 position, plant-derived oils such as POL and its modified products have a smaller effect on abdominal fat deposition.…”
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Effect of soil-groundwater system on migration and transformation of organochlorine pesticides: A review by Haohao Li, Lin Huo, Rui Zhang, Xuefan Gu, Gang Chen, Ying Yuan, Wenbing Tan, Kunlong Hui, Yu Jiang

“…Soil is the place where human beings, plants, and animals depend on for their survival and the link between the various ecological layers. …”
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