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10921
Investigating the antioxidant effects of Cucurbita maxima Duchesne extract on motor coordination and memory impairment induced by scopolamine in rats
Published 2024-12-01“…Results: The results from the MWM indicated that animals receiving SCOP along with CM extract at concentrations of 50, 100, and 200 mg/kg spent significantly more time on the target platform compared to the SCOP-only group. …”
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10922
Current Status and Global Research Trend Patterns of Insect Meal in Aquaculture From Scientometric Perspective: (2013–2022)
Published 2024-01-01“…In the past decade, insect meal has gained popularity in the animal feed industry, particularly in aquafeed, due to rising costs and decreased availability of fish meal (FM) and fish oil. …”
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10923
Chemical Changes Under Heat Stress and Identification of Dendrillolactone, a New Diterpene Derivative with a Rare Rearranged Spongiane Skeleton from the Antarctic Marine Sponge <i>...
Published 2024-12-01“…This polar area is home to a large and rich community of benthic marine invertebrates, such as sponges, tunicates, corals, and many other animals. Among the sponges, the bright yellow <i>Dendrilla antarctica</i> is commonly known for using secondary diterpenoids as a defensive mechanism against local potential predators. …”
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10924
Pathogen Detection and Resistome Analysis in Healthy Shelter Dogs Using Whole Metagenome Sequencing
Published 2025-01-01“…According to the Humane Society, 25 to 40 percent of pet dogs in the United States are adopted from animal shelters. Shelter dogs can harbor bacterial, viral, fungal, and protozoal pathogens, posing risks to canine and human health. …”
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10925
Physical Activity and Quality of Life in Retinitis Pigmentosa
Published 2017-01-01“…Aerobic exercise has been found to be neuroprotective in animal models of retinal degeneration. This study aims to report physical activity levels in patients with RP and investigate the relationship between physical activity and vision-related quality-of-life (QOL). …”
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10926
Noise-induced ribbon synapse loss in the mouse basal cochlear region does not reduce inner hair cell exocytosis
Published 2025-01-01“…Depolarization-evoked calcium currents in IHCs 2 weeks after exposure were slightly but not significantly smaller as compared to controls from age-matched non-exposed animals. Exocytic changes monitored as changes in membrane capacitance did not follow that trend and remained similar to controls despite significant loss of ribbons, likely reflecting increased exocytosis at the remaining synapses. …”
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10927
Renal glomerular and tubular injury in the offspring of the preeclampsia-like syndrome
Published 2025-01-01“…Epidemiological studies and animal experiments have demonstrated that PE adversely affects the cardiovascular and nervous systems of offspring, increasing their risk of hypertension and renal pathology. …”
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10928
The effect of vitamin and mineral supplementation on pregnancy rates in kangal sheep during the breeding season
Published 2022-06-01“…<p> <b>Materials and Methods:</b> The presented study was carried out with 200 Kangal ewe. The animals included in the study were randomly divided into four equal groups. …”
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10929
Stem Cell Therapy for the Treatment of Amyotrophic Lateral Sclerosis: Comparison of the Efficacy of Mesenchymal Stem Cells, Neural Stem Cells, and Induced Pluripotent Stem Cells
Published 2024-12-01“…NSCs, isolated from the fetal spinal cord or brain, demonstrate promise in animal models but face functional integration and ethical challenges. iPSCs, created by reprogramming patient-specific somatic cells, offer a novel approach by potentially replacing or supporting neurons. iPSC therapy addresses ethical issues related to embryonic stem cells but encounters challenges regarding genotoxicity and epigenetic irregularities, somatic cell sources, privacy concerns, the need for extensive clinical trials, and high reprogramming costs. …”
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10930
Effect of diabetes mellitus on levels of insulin-like growth factors and their carrier proteins in Guerin’s carcinoma and it’s perifocal tissue in rats
Published 2021-12-01“…Experimental DM was reproduces in animals by the single intraperitoneal alloxan injection (150 mg/kg body weight). …”
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10931
Effects of Muse Cell on a Mouse Model With Acute Encephalopathy
Published 2025-01-01“…We aimed to examine the effects of Muse cells in a cytokine storm–induced AE animal model using immunocompromised nonobese diabetic/severe combined immunodeficiency (NOD/SCID) neonatal mice. …”
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10932
Activities and programmes that support the emotional wellness and well-being of refugees, immigrants and other newcomers within settlement agencies: a scoping review protocol
Published 2020-09-01“…The article searches will take place between August and October 2020.Ethics and dissemination Ethics is not required as the research will not involve human or animal subjects. The research is a scoping review, and thus relies on published and grey literature studies and documents. …”
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10933
Aerobic capacity and muscle proteome: Insights from a mouse model
Published 2025-02-01“…In McArdle mice, the proteins associated with AC were involved in skeletal muscle fibre differentiation/development, lipid oxidation, mitochondrial function and calcium homeostasis, whereas in wild‐type animals AC‐associated proteins were related to cytoskeleton structure (intermediate filaments), cell cycle regulation and endocytic trafficking. …”
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10934
A synergistic effect of secondhand smoke with vitamin D deficiency on cognitive impairment in older adults: a cross sectional study
Published 2025-02-01“…Although it only had an association with cognitive impairment indicated by DSST and the Animal Fluency test (AFT) in the crude model, SHS exposure showed significant synergistic effects with VDD on DSST (aOR: 3.03, 95% CI: 1.57 ~ 5.83, Pinteraction = 0.001) and AFT (aOR: 2.40, 95% CI: 1.34 ~ 4.29, Pinteraction = 0.003), respectively, after adjusting for the possible confounders. …”
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10935
ALKBH3-mediated m1A demethylation promotes the malignant progression of acute myeloid leukemia by regulating ferroptosis through the upregulation of ATF4 expression
Published 2025-12-01“…To investigate the role of ALKBH3 in acute myeloid leukemia (AML), we constructed an animal model of xenotransplantation of AML. Our study demonstrated that ALKBH3-mediated m1A demethylation inhibits ferroptosis in KG-1 cells by increasing ATF4 expression, thus promoting the development of AML. …”
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10936
Colorectal Peritoneal Metastases: A Systematic Review of Current and Emerging Trends in Clinical and Translational Research
Published 2019-01-01“…A systematic review in accordance with PRISMA guidelines was undertaken on all English language studies published between 2007 and 2017. In vitro and animal model studies were deemed eligible for inclusion in the sections pertaining to biomarkers and therapeutic optimisation, as these areas of research currently remain in the early stages of development. …”
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10937
Salidroside promotes pro-angiogenesis and repair of blood brain barrier via Notch/ITGB1 signal path in CSVD Model
Published 2025-02-01“…Subsequently, the MRI, pathomorphism, as well as Morriss water maze test were conducted to determine CSVD-related indicators. 8 weeks post-surgery, animals were randomly administered SAL, DAPT, ATN161 or saline.The aim was to explore the protective effects of SAL in CSVD as well as its possible mechanism. …”
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10938
Mutation in CDC42 Gene Set as a Response Biomarker for Immune Checkpoint Inhibitor Therapy
Published 2025-01-01“…Furthermore, our analysis of immune response landscapes among different statuses of the CDC42 gene set supports its role as a biomarker. Animal experiments also revealed that the combination of the CDC42 inhibitor (ML141) with anti‐PD‐1 blockade can additively reduce tumor growth. …”
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10939
Iron Content of Some Popular Cooked Foods Consumed by the Rural School Children in Sri Lanka
Published 2019-01-01“…Iron deficiency is common in populations consuming cereal-based diets with little or no animal-derived food products. Rice is the staple for Sri Lankans, which may not provide sufficient bioavailable iron. …”
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10940
Nonpharmacological Treatment for Supporting Social Participation of Adults with Depression
Published 2021-01-01“…Conclusion. Both OBI such as animal-assisted therapy and CBT-BI such as behavioral change program and health education have a strong level of certainty and low risk of bias in promoting social participation by supporting positive behavioral change and reducing depressive symptoms. …”
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