Antimicrobial use regulations are associated with increased susceptibility among bovine Salmonella isolates from a U.S. surveillance system by Claudia Cobo-Angel, Maya Craig, Marwan Osman, Kevin J. Cummings, Casey L. Cazer

“…Health authorities around the world have called to limit antimicrobial use in food-producing animals. In the United States, two recent regulatory actions have changed the use of antimicrobials in livestock, banning production uses in 2017 and restricting extra-label use of cephalosporins in 2012. …”
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Development of a conjunctival contact–type drug delivery device for latanoprost using hyaluronic acid by Soomin Lee, Mi-Young Jung, Choul Yong Park

“…However, these results are based on animal testing, so further development is needed for clinical use.…”
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Evaluation of the Digital Ventilated Cage® system for circadian phenotyping by Selma Tir, Russell G. Foster, Stuart N. Peirson

“…C57BL/6J mice exhibited a 24 h period under light/dark conditions, with a free-running period of 23.5 h under constant dark, and period lengthening under constant light. Animals displayed expected phase shifting responses to jet-lag and nocturnal light pulses. …”
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Traffic-related-air-pollutant PM2.5 Caused Toxicity on Caenorhabditis elegans with Cotreatment of High-dose Glucose and Tempeh by Jian-He Lu, Ming-Hsien Tsai, Sen-Ting Huang, Jia-De Lee, Ta-Chih Hsiao, Wan Nurdiyana Wan Mansor, How-Ran Chao

“…Using Caenorhabditis elegans (C. elegans) as an in vivo animal model, we found that exposure to 12.74 mg L−1 TRAP PM2.5 and 80 mM D-glucose could induce toxicity in nematodes that affects growth, reproduction, locomotion behavior, and lifespan. …”
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Selection of an optimal method for screening the collection of narrow-leaved lupine held by the Vavilov Institute for the qualitative and quantitative composition of seed alkaloids by A. V. Kushnareva, Т. V. Shelengа, I. N. Perchuk, G. P. Egorova, L. L. Malyshev, Yu. A. Kerv, A. L. Shavarda, M. A. Vishnyakova

“…However, the presence of secondary metabolites – alkaloids – in lupine seeds considerably affects the quality of raw produce, reducing its nutritive value; in addition, high concentrations of alkaloids are toxic to humans and animals. Therefore, plant breeders working with lupine need to gain knowledge about the variability of alkaloid content in seeds of different genotypes and search for the sources of their low concentrations in the crop’s gene pool. …”
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AFP shields hepatocellular carcinoma from macrophage phagocytosis by regulating HuR-mediated CD47 translocation in cellular membrane by Yinglian Pan, Qiushi Yin, Zhaoliang Wang, Gang Wu, Kun Liu, Xiaowei Li, Jinchen Liu, Jiangzheng Zeng, Bo Lin, Wei Li, Mingyue Zhu, Mengsen Li

“…The effect of AFP on regulating the level of CD47 in cellular membrane and growth of tumor in vivo was performed by animal experiment. The association of AFP and CD47 in HCC cells was detected by single cell analysis. …”
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Attenuation of Myocardial Injury by HMGB1 Blockade during Ischemia/Reperfusion Is Toll-Like Receptor 2-Dependent by Jan Mersmann, Franziska Iskandar, Kathrina Latsch, Katharina Habeck, Vera Sprunck, René Zimmermann, Ralf R. Schumann, Kai Zacharowski, Alexander Koch

“…Injection of HMGB1 did, however, not increase infarct size in WT animals. In TLR2−/−-hearts, neither BoxA nor HMGB1 affected infarct size. …”
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Physical activity, Vitamin D, and all-cause/cardiovascular mortality: a prospective study in older Chinese adults by Mingrui Chen, Ling Cheng, Sisi Yang, Yan Zhang

“…Furthermore, vitamin D accounted for a greater mediating proportion in the physical activities of housework and raising domestic animals/pets. Conclusions Physical activity could reduce the risk of all-cause/cardiovascular mortality and was mediated by vitamin D in older Chinese adults.…”
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Lack of intracranial atherosclerosis in various atherosclerotic mouse models by Diewertje I Bink, Katja Ritz, Claire Mackaaij, Olga Stam, Sanny Scheffer, Mark R Mizee, Hanneke J Ploegmakers, Bert J van het Hof, Onno J de Boer, Judith C Sluimer, Guido R Y De Meyer, Louise van der Weerd, Helga E de Vries, Mat J A P Daemen

“…Since intracranial atherosclerosis is a common cause of stroke and is associated with dementia, a relevant animal model is needed to study these diseases. We examined the presence of intracranial atherosclerosis in different atherogenic mouse strains and studied differences in vessel wall characteristics in mouse and human tissue in search of possible explanations for the differing atherosclerotic susceptibility between extracranial and intracranial vessels. …”
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Optimizing Fresh-Cut Apple (Malus sylvestris (L.) Mill.) Quality Through Combination of Sodium Alginate and Calcium Chloride Coatings by Maharani Retna Duhita, Muhammad Khairul Ikhsan

“…The study was conducted at the Biochemistry and Food Laboratory of the Biology Study Program of UIN Maulana Malik Ibrahim Malang and the Animal Husbandry Laboratory of Universitas Brawijaya. …”
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Contamination of Japanese Retail Foods With Enterotoxigenic Clostridium Perfringens Spores by Takahiro Ohnishi, Maiko Watanabe, Yusuke Yodotani, Emiri Nishizato, Seiya Araki, Satomi Sasaki, Yukiko Hara-Kudo, Yuka Kojima, Naoaki Misawa, Nobuhiko Okabe

“…The contamination of Japanese retail foods and the intestinal contents of animals with the spores of enterotoxigenic Clostridium perfringens were investigated by analyzing clostridial toxin genes (cpa and cpe) using a culture method and PCR. …”
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Plasticizers May Activate Human Hepatic Peroxisome Proliferator-Activated Receptor α Less Than That of a Mouse but May Activate Constitutive Androstane Receptor in Liver by Yuki Ito, Toshiki Nakamura, Yukie Yanagiba, Doni Hikmat Ramdhan, Nozomi Yamagishi, Hisao Naito, Michihiro Kamijima, Frank J. Gonzalez, Tamie Nakajima

“…However, species differences in the receptor functions between rodents and human make it difficult to precisely extrapolate their toxicity from animal studies to human. In this paper, we compared the species differences in the activation of mouse and human hepatic PPARα by these plasticizers using wild-type (mPPARα) and humanized PPARα (hPPARα) mice. …”
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Assessing the dynamics of  Mycobacterium bovis infection in three French badger populations by Calenge, Clément, Payne, Ariane, Réveillaud, Édouard, Richomme, Céline, Girard, Sébastien, Desvaux, Stéphanie

“…In all the clusters, the infection was strongly spatially structured, whereas the mean correlation between the infection status of the animals trapped in the same commune was negligible. …”
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Lactoferrin: a secret weapon in the war against pathogenic bacteria by Lucero Ruiz-Mazón, Gerardo Ramírez-Rico, Mireya de la Garza

“…Because of its effectiveness, accessibility, low cost, and nontoxicity, Lf could be a promising alternative for preventing or treating infections in animals and humans.…”
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The effect of space flight on genes expression in brain by A. S. Tsybko, T. V. Ilchibaeva, N. K. Popova

“…Decreased genetic control of the dopamine system may contribute to the spaceflight-induced locomotor impairment and dyskinesia described for both animals and humans. Also, the system of neuronal apoptosis is activated under the influence of microgravity as evidenced by changes in the expression of antiapoptotic protein Bcl-XL in the hippocampus and hypothalamus. …”
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Interferon gamma‐mediated prevention of tumor progression in a mouse model of multiple myeloma by Zoltán Kellermayer, Sabrin Tahri, Madelon M. E. deJong, Natalie Papazian, Cathelijne Fokkema, Elodie C. G. Stoetman, Remco Hoogenboezem, Gregory vanBeek, Mathijs A. Sanders, Louis Boon, Chelsea Den Hollander, Annemiek Broijl, Pieter Sonneveld, Tom Cupedo

“…Transfer of 5TGM1 cells in C57Bl/6 mice led to stable disease with low tumor burden in a subset of animals. Stable disease was associated with sustained activation and expansion of NK cells, ILC1, and CD8+ T cells, a response that was lost upon disease progression. …”
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Advancing Food Security with Farmed Edible Insects: Economic, Social, and Environmental Aspects by José E. Aguilar-Toalá, Abraham M. Vidal-Limón, Andrea M. Liceaga

“…From a socioeconomic point of view, edible insects have lower production costs compared to conventional animal protein sources because of their high feed efficiency conversion, rapid growth rate, and short life cycles. …”
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Recherche-action et promotion écocentrée : expériences de refondation mémorielle et de construction territoriale à partir d’une écriture située by Maria Luisa Mura

“…À partir de l’analyse du terrain de recherche mené dans le village et de l’animation littéraire qui en a suivi, il sera question de montrer la validité analytique et le potentiel applicatif de la recherche-action en littérature (au sein de l’écocritique matérielle notamment) dans un contexte promo­tionnel régional et périurbain, à l’intérieur de l’horizon méthodologique et opérationnel ample des parcs et des promenades littéraires. …”
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Effects of molybdenum to growth parameters and lipid content of two algae in Scenedesmaceae taxa by Celal Caner, Dilara Erdaği, Büşranur Şeker, Hüseyin Altundağ, Gizem Çeti̇n, Hatice Tunca

“…Although this compound provides the catalysis and electron transport of many biochemical reactions, it causes serious health problems in animals at high concentrations. For this reason, its recovery of water resources is one of the main subjects of scientific studies called bioremediaiton. …”
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Possible erythropoietin pharmacotherapeutic targets on painful diabetic neuropathy in rats by SAMUEL SUAREZ-MENDEZ, DEYSI Y. BERMÚDEZ-OCAÑA

“…Current evidence indicates that erythropoietin exerts pleiotropic effects in animal models. However, its role in painful diabetic neuropathy, as well as the possible action mechanisms are not yet established. …”
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