Discovery of conserved peptide-MHC epitopes for directly alloreactive CD8+ T cells by Alexandra E. Hill, Eric T. Son, Moumita Paul-Heng, Chuanmin Wang, Shivanjali Ratnaseelan, Martina Denkova, Pouya Faridi, Asolina Braun, Anthony W. Purcell, Nicole A. Mifsud, Alexandra F. Sharland

“…In conclusion, small animal studies have demonstrated the feasibility of high-throughput approaches for the discovery of pMHC epitopes recognised by directly alloreactive T cells. …”
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Protective role of vitamin D receptor against mitochondrial calcium overload from PM2.5-Induced injury in renal tubular cells by Mengqiu Lu, Zishun Zhan, Dan Li, Hengbing Chen, Aimei Li, Jing Hu, Zhijun Huang, Bin Yi

“…Purpose: This research explores the consequences of being exposed to PM2.5 contribute to renal injury while also evaluating the protective role of Vitamin D-VDR signaling in alleviating mitochondrial calcium imbalance and oxidative stress in renal tubular cells. Methods: Animal models of chronic PM2.5 exposure were used to simulate environmental conditions in wild type and VDR-overexpressing mice specific to renal tubules. …”
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Cottonseed Meal Protein Hydrolysate Improves the Growth Performance of Chinese Mitten Crab (Eriocheir sinensis) by Promoting the Muscle Growth and Molting Performance by Chao-Fan He, Wen-Bin Liu, Ling Zhang, Wei-Liang Chen, Zi-Shang Liu, Xiang-Fei Li

“…Plant protein hydrolysates contain a large number of small peptides and free amino acids, which can improve the growth performance of aquatic animals. However, the potential mechanisms are still not well elucidated. …”
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Medicinal plants with neuroprotective potential in East African countries: A systematic review by Ibe Michael Usman, Ekom Monday Etukudo, Elna Owembabazi, Wusa Makena, Augustine Oviosun, Makeri Danladi, Vivian Ojiakor, Patrick Maduabuchi Aja, Emeka Anyanwu, Yanurkis Duranones Rosales, Mario Edgar Fernandez Diaz, Josiah Ifie, Ismahil Adekunle Adeniyi, Ilemobayo Victor Fasogbon, Victor Bassey Archibong

“…Method: The present study is a systematic review that included randomized controlled trial studies using experimental animal models for various nervous system related conditions treated with medicine plants sourced from within any of the East African countries. …”
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Topical Application of Orabase Bromelain Gel Reduces Inflammatory Process, Bone Loss and Steatosis in Experimental Periodontitis by Even Herlany Pereira Alves, Hélio Mateus Silva Nascimento, Luiz Felipe de Carvalho França, Any Carolina Cardoso Guimarães Vasconcelos, Larissa dos Santos Pessoa, Felipe Rodolfo Pereira da Silva, John Arlley Sousa Pinho de Lira, Paulo Roberto Carneiro Gomes, André dos Santos Carvalho, André Luiz dos Reis Barbosa, Daniel Fernando Pereira Vasconcelos

“…The bromelain-based gel was formulated in two concentrations (1% and 10%). Ten animals were used per group: Control, Periodontitis, Periodontitis + Neutral Gel, Periodontitis + 1% Bromelain Gel, Periodontitis + 10% Bromelain Gel and Periodontitis + 2% Chlorhexidine Gel. …”
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Activation of KATP channels in pain modulation: a systematic review of preclinical studies by Signe Schønning Beich, Lili Kokoti, Mohammad Al-Mahdi Al-Karagholi, Mohammad Al-Mahdi Al-Karagholi

“…The main findings of the present systematic review were that KATP channel openers can attenuate induced pain in various animal models and potentiate the effects of analgesics.ConclusionLocal, systemic, spinal, and supraspinal activation of KATP channels can attenuate pain and potentiate the efficacy of analgesic drugs. …”
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Drought and rural communities: strategies to deal with its consequences (Case study: Border Rural of Zahedan Township) by masood safari aliakbari, mohammad reza poodineh, mohammad azadpour

“…The results showed that drought in Zahedan city villages had the greatest effect on reducing water resources, cultivation, employment, income, rural poverty, number of livestock or animal products, rural migration, vegetation loss, erosion and soil salinity and reduced price Had land and land. …”
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Depth-electrode stimulation and concurrent functional MRI in humans: Factors influencing heating with body coil transmission by Hiroyuki Oya, Ralph Adolphs, Matthew A. Howard, J. Michael Tyszka

“…Widely used to map effective functional connectivity in animal studies, its application to the human brain has been limited due to safety concerns. …”
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Chelate compounds and their use for correction of trace element deficiencies in livestock (review) by A. G. Koshchaev, N. E. Gorkovenko, A. V. Kosykh, D. V. Antipova

“…The mechanism of biological action of chelate compounds and the pathogenesis of trace element deficiencies in animals are considered, while the advantages of chelate compound use in microelementoses therapy and prevention are specified.…”
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The guanine nucleotide exchange factor DOCK5 negatively regulates osteoblast differentiation and BMP2-induced bone regeneration via the MKK3/6 and p38 signaling pathways by Ju Ang Kim, Soomin Im, Jiwon Lim, Jung Min Hong, Hye Jung Ihn, Jong-Sup Bae, Jung-Eun Kim, Yong Chul Bae, Eui Kyun Park

“…Osteoblast differentiation and bone regeneration were analyzed using bone marrow mesenchymal stem cells (BMSCs) and various animal models. C21 significantly enhanced osteoblast differentiation and mineral deposition in mouse MC3T3-E1 cells and in human and mouse BMSCs. …”
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Effect of dietary lecithin on antioxidant defense of rainbow trout, Oncorhynchus mykiss broodstock and offspring by Fatemeh Jafari, Naser Agh, Farzaneh Noori, Abdoljabbar Irani, Reyhaneh Ravanbakhsh, Mahdi Imani

“…Introduction: Soybean lecithin (SBL) is usually added to aquafeed as a phospholipids source because aquatic animals including crustaceans and fish cannot synthesize phospholipids. …”
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Multidrug-Resistant Salmonella enterica Serovar Rissen Clusters Detected in Azores Archipelago, Portugal by Leonor Silveira, Miguel Pinto, Joana Isidro, Ângela Pista, Patrícia Themudo, Luís Vieira, Jorge Machado, João Paulo Gomes

“…In the present study, we analyzed by whole genome sequencing (WGS) all clinical, animal, food, and environmental isolates received up to 2017 in the Portuguese Reference Laboratories. …”
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Characterization of Cantal and Salers Protected Designation of Origin Cheeses Based on Sensory Analysis, Physicochemical Characteristics and Volatile Compounds by Cécile Bord, Louis Lenoir, Julie Benoit, Delphine Guérinon, Gilles Dechambre, Christophe Chassard, Christian Coelho

“…The PDO Salers cheeses presented the highest flavor variability compared to the PDO Cantal cheeses due to compounds belonging to alcohols, acids, aldehydes and ester conferring ammonia, vegetal and animal flavors compared to the PDO Cantal cheeses that were perceived as more pungent and bitter.…”
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Prevention of Foodborne Listeriosis by JM Farber, J Harwig, A Carter

“…Included among these recommendations is avoidance of consumption of potentially hazardous foods such as soft cheese and raw products of animal origin.…”
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The effect of high-sugar feeding on rodent metabolic phenotype: a systematic review and meta-analysis by Sophie Lucic Fisher, G. Jean Campbell, Alistair Senior, Kim Bell-Anderson

“…Additionally, many preclinical animal studies provide liquid sugar which more readily leads to excess consumption and weight gain, confounding any outcomes driven by high-sugar intake alone. …”
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Synoptic Analysis of Early Heat Waves in Northwest of Iran by Mahmoud Hooshyar, behrouz sobhani, nader parvin

“…Early heat waves are extreme events that cause heavy losses in plant and animal life and cause many social and economic problems for communities. …”
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Evaluación del bienestar bovino: Evolución hacia el enfoque de los 5 Dominios by Sonia Alejandra Romera, María Eugenia Munilla, Catalina Medrano-Galarza

“… El bienestar animal positivo es un concepto novedoso que valoriza la importancia de las experiencias gratas de vida para contribuir al estado mental. …”
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Clinical outcomes and long-term efficacy of high tibial osteotomy in treating knee instability: An updated systematic review by Mustamsir Edi, Aji Aulia Pandu, Adiwangsa Ahmad Abdilla, Akmalizzan Azfar Ahnaf

“…Exclusion criteria included animal studies, non-knee joint studies, and reviews. …”
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Tangduqing Granules Attenuate Insulin Resistance and Abnormal Lipid Metabolism through the Coordinated Regulation of PPARγ and DGAT2 in Type 2 Diabetic Rats by Qinghua Zhang, Yingying Huang, Xiaojin Li, Hongyi Liu, Baichuan He, Bin Wang, Yuntao Ma, Xiang Zhou, Yaqin Liu, Shentao Wu

“…The present study is aimed at evaluating a Chinese medicinal formula, Tangduqing granules (TDQ), with multifaceted actions against lipid and glucose metabolism disorder and IR of type 2 diabetes. An animal model of type 2 diabetes was developed by high-fat diet feeding plus low-dose streptozotocin injection. …”
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Recovery response of coenzyme Q10 to exercise-related physiological muscle damage, inflammation and oxidative stress: A systematic review by Muhammet Enes Yasul, Vedat Çınar, Yavuz Yasul, Büşra Yılmaz, Ömer Şenel

“…In the analysis, one study was conducted with experimental animals, two studies were conducted with male and female participants, and 12 studies were conducted with only male participants. …”
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