miR-224-5p Attenuates Allergic Responses in Mice with Allergic Rhinitis by Modulating the Th1/Th2 Response by Yuxiao Li, Ran An, Mingjin Wu, Jiayan He, Xiaoguang He

“…Human nasal epithelial cells (HNEpCs) were used to establish an AR cell model induced by Der P1, and C57BL/6 mice were used to establish an AR animal model induced by OVA (ovalbumin). RT-qPCR was used to determine the level of miR-224-5p; western blot analysis was used to determine GATA3; ELISA was used to determine the levels of OVA-specific IgE, IFN-γ, IL-4, IL-5, and IL-13; flow cytometry was used to determine the differentiation of Th1 and Th2 cells; and HE and PAS staining was used to observe the histopathological alterations in the mouse nasal mucosa and spleen. …”
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From deadly to life-saving effects: antimicrobial and antibiofilm effects of tarantula cubensis extract on bacterial and fungal pathogens by Elif AYDIN

“…Such natural poisons offer a promising and powerful solution to control microbial populations, combat pathogens, and protect human and animal health.…”
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Sistem Kontrol Kadar Amonia Dan Tinggi Air Pada Kolam Penangkaran Tukik Penyu by Riego Pitos Hababil, Budi Rahmadya

“… Turtles are also one of the animals whose population is decreasing day by day due to several factors ranging from climate change, disease, environmental damage and inadequate processing of conservation techniques and so on. …”
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LIFEPLAN: A worldwide biodiversity sampling design. by Bess Hardwick, Deirdre Kerdraon, Hanna M K Rogers, Dimby Raharinjanahary, Eric Tsiriniaina Rajoelison, Tommi Mononen, Petteri Lehikoinen, Gaia Banelyte, Arielle Farrell, Brian L Fisher, Tomas Roslin, Otso Ovaskainen

“…We describe the steps to collect sequences of animal images (.jpg) from infrared triggered camera traps, audio data (.WAV) of environment sounds from audio recorders, invertebrate samples in ethanol from Malaise traps for DNA metabarcoding, as well as both soil samples and 24-hour air samples obtained from cyclone samplers for fungal DNA metabarcoding. …”
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Spatial Morphology and Geographic Adaptability of Traditional Villages in the Hehuang Region, China by Xinhong Zhang, Haiqin Yang, Yuyuan An

“…Their spatial pattern facilitates agriculture and animal husbandry, with streets and alleys being predominantly grid-shaped, S-shaped, and Z-shaped. (3) The spatial morphology of both types of villages is well-adapted to local terrain and climate conditions, as well as to the resident’s requirements for water use and disaster prevention, which reflects the wisdom of the Hehuang region’s ancestors regarding settlement construction. …”
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Profile and Geospatial Analysis of Dog Bite Cases Attending the Antirabies Vaccine Outpatient Department at the Tertiary Level Hospital of Mumbai by Dinesh Asokan, Anjali Mall, Lalit Sankhe, Nagaraj Jaganathasamy, Geeta Pardeshi

“…Adopting the One Health approach, which considers the interconnection of human, animal, and environmental health, is vital for developing effective interventions. …”
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Anatomical, functional, and blood-born predictors of severity of brachycephalic obstructive airway syndrome severity in French Bulldogs by Claudia Schmid, Claudia Schmid, Claudia Schmid, Aline R. Steiner, Léonie Spielhofer, Léonie Spielhofer, Meltem Galfetti, Meltem Galfetti, Nikki Rentsch, Nikolay Bogdanov, Johannes Vogel, Regina Hofmann-Lehmann, Regina Hofmann-Lehmann, Sonja Hartnack, Georgy Astakhov, Reinhard Furrer, Anna Bogdanova, Anna Bogdanova, Iris Margaret Reichler

“…Among the limitations of this study are the focus on one breed and the low number of animals with severe clinical signs of BOAS in the study cohort.…”
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Global remapping emerges as the mechanism for renewal of context-dependent behavior in a reinforcement learning model by David Kappel, Sen Cheng

“…., place cell activity during spatial navigation in rodents or remapping of place fields when the animal switches between contexts. Furthermore, rodents show context-dependent renewal of extinguished behavior. …”
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Combined Treatment with Zinc Aspartate and Intravenous Immunoglobulins (IVIGs) Ameliorates Experimental Autoimmune Encephalomyelitis (EAE) by Diana Straubel, Anja Thielitz, Annegret Reinhold, Kurt Grüngreiff, Dirk Reinhold

“…The aim of the present study was to investigate the influence of IVIG (Octagam®), zinc aspartate (Unizink®), and the combined application of both preparations in the experimental autoimmune encephalomyelitis (EAE), the animal model of MS. Therapeutic intraperitoneal application of zinc aspartate significantly diminished clinical signs during the relapsing-remitting phase of EAE in SJL/J mice. …”
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THE METHOD OF DESIGNING HYDRAULIC DRIVES ON THE EXAMPLE OF A HYDRAULIC DRIVE OF A LIFTING-MAST DEVICE by S. A. Smirnov, N. A. Gorshkova

“…For visual display an animated 3D model has been created that allows you to observe the progress and results of the simulation. …”
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Effect of Global ATGL Knockout on Murine Fasting Glucose Kinetics by Margarida Coelho, Patricia Nunes, Vera M. Mendes, Bruno Manadas, Arend Heerschap, John G. Jones

“…Measurement of endogenous glucose production (EGP) and Cori cycle activity provide insights into the maintenance of glycemic control in these animals. These parameters were determined in 7 wild-type (ATGL+/−) and 6 ATGL−/− mice by a primed-infusion of [U-13C6]glucose followed by LC-MS/MS targeted mass-isotopomer analysis of blood glucose. …”
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Characteristics and Functional Properties of Bioactive Oleogels: A Current Review by Md. Jannatul Ferdaus, Niaz Mahmud, Sudipta Talukder, Roberta Claro da Silva

“…They provide a healthier alternative to traditional solid or animal fats. They have improved oxidative stability and nutritional value to maintain the desirable sensory qualities of lipid-based foods. …”
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Oral Administration of Piperine as Curative and Prophylaxis Reduces Parasitaemia in Plasmodium berghei ANKA-Infected Mice by Shafia Khairani, Nisa Fauziah, Hesti Lina Wiraswati, Ramdan Panigoro, Endang Yuni Setyowati, Afiat Berbudi

“…Piperine 40 mg/kg bw in curative and prophylactic tests had the maximum parasitaemia chemosuppression of 79.21% and 58.8% (p < 0.05), respectively, with a significant effect on the survival rate compared with control animals. In the curative test, piperine 40 mg/kg bw reduced the mean clinical score compared with the control group. …”
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Les services écologiques des bonobos (Pan paniscus) by David Beaune, François Bretagnolle, Loïc Bollache, Chloé Bourson, Gottfried Hohmann, Barbara Fruth

“…Survival of Afrotropical primary forests depends not only on habitat protection but also on the protection of animal species such as frugivorous primates, recognized as the most important seed dispersers for many plants. …”
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Mast Cells Positive to Tryptase and c-Kit Receptor Expressing Cells Correlates with Angiogenesis in Gastric Cancer Patients Surgically Treated by Michele Ammendola, Rosario Sacco, Giuseppe Sammarco, Giuseppe Donato, Valeria Zuccalà, Roberto Romano, Maria Luposella, Rosa Patruno, Carlo Vallicelli, Giorgio Maria Verdecchia, Davide Cavaliere, Severino Montemurro, Girolamo Ranieri

“…Angiogenesis is a complex process involved in both growth and progression of several human and animal tumours. Tryptase is a serin protease stored in mast cells granules, which plays a role in tumour angiogenesis. …”
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RETHINKING CLIMATE CHANGE AND NATIONAL SECURITY: IMPLICATIONS FOR SUSTAINABLE DEVELOPMENT IN NIGERIA by AUSTEEN NDUBUISI ADIGWE

“…This ranges from decreased precipitation to deforestation and desertification, the poleward shift of vegetation and its impact on animal populations, the unmitigated rise in sea levels among others. …”
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The effects of quercetin on antioxidant system and some blood parameters in rats exposed to acute cadmium toxicity by İhsan Kısadere, Nurcan Dönmez

“…Blood samples were collected from all animals at fourth day after treatments.<p> <b>Results:</b> The levels of serum SOD, MDA, GSH, catalase, and plasma ALT, AST, GGT, total protein, albumin were detected. …”
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BMP6, a potential biomarker of inflammatory fibrosis and promising protective factor for dilated cardiomyopathy by Feng Jiang, Jiayang Tang, Xiaoqi Wei, Hai Pan, Xinyi Fan, Peng Zhang, Shuzhen Guo

“…Method Bulk RNA-seq, single-cell RNA-seq, Mendelian randomization analysis, animal model construction, and BMP6 knockdown were utilized to identify and validate potential specific markers and targets for intervention in DCM heart failure. …”
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Quarter-Millimeter-Resolution Molecular Mouse Imaging with U-SPECT by Oleksandra Ivashchenko, Frans van der Have, Jose L. Villena, Harald C. Groen, Ruud M. Ramakers, Harrie H. Weinans, Freek J. Beekman

“…Limited spatial resolution of preclinical positron emission tomography (PET) and single-photon emission computed tomography (SPECT) has slowed down applications of molecular imaging in small animals. Here we present the latest-generation U-SPECT system (U-SPECT + , MILabs, Utrecht, the Netherlands) enabling radionuclide imaging of mice with quarter-millimeter resolution. …”
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Mutations in Homocysteine Metabolism Genes Increase Keratin N-Homocysteinylation and Damage in Mice by Kamila Borowczyk, Jacek Wróblewski, Joanna Suliburska, Noriyuki Akahoshi, Isao Ishii, Hieronim Jakubowski

“…The accumulation of N-Hcy in hair keratin led to a progressive reduction of N-Hcy-keratin solubility in sodium dodecyl sulfate, from 0.39 ± 0.04 in wild-type mice to 0.19 ± 0.03, 0.14 ± 0.01, and 0.07 ± 0.03 in Mthfr−/−, Cse−/−, or Cbs−/−animals, respectively. N-Hcy-keratin accelerated aggregation of unmodified keratin in Cbs−/− mouse hair. …”
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