Qufeng epimedium decoction alleviates rheumatoid arthritis through CYLD-antagonized NF-kB activation by deubiquitinating Sirt1 by Zhiming Wu, Peng Zhang, Wenyan Huang, Yifen Zhou, Zhengliu Cao, Chunhong Wu

“…However, its underlying mechanism remains elusive. Methods: The RA animal model was established to investigate the anti-RA effect and regulatory effect on fibroblast-like synoviocytes (FLS) pyroptosis, qRT-PCR, Western blot, flow cytometry, histology staining, and ELISA were utilized to confirm the gene and protein expressions. …”
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Enhancing Spatial Memory: Anxiolytic and Antidepressant Effects of Tapinanthus dodoneifolius (DC) Danser in Mice by Foyet Harquin Simplice, Tsala David Emery, Ngatanko Abaissou Hervé Hervé

“…In the forced swimming test, the immobility time of the animal was significantly reduced (P<0.05) by TAE (100 mg/kg), compared to control, and this effect was quite comparable to that of imipramine. …”
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Effect of single ethanol administration on behavior and the consumption and preference of ethanol in tame and aggressive rats by R. V. Kozhemyakina, S. G. Shikhevich, A. Cagan, R. G. Gulevich

“…However, data obtained with experimental animals do not always confirm this statement. Model strains of Norway rats selected for tame and aggressive attitude to humans are some of the models for investigation of relationships among anxiety, the function of the hypothalamus – pituitary – adrenal (HPA) axis, and predisposition to alcohol addiction. …”
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Cellular Immunogenicity of Novel Gene Immunogens in Mice Monitored by in Vivo Imaging by Elizaveta Starodubova, Olga Krotova, David Hallengärd, Yulia Kuzmenko, Gunnel Engström, Diana Legzdina, Oleg Latyshev, Olesja Eliseeva, Anna Karin Maltais, Vera Tunitskaya, Vadim Karpov, Andreas Bråve, Maria Isaguliants

“…In vivo imaging performed as an animal-sparing method to estimate the overall performance of DNA immunogens, predicting it early in the experiment. …”
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Cognitive profile in mild cognitive impairment with Lewy bodies by Shuai Liu, Chunyan Liu, Xiao-Dan Wang, Huiru Lu, Yong Ji

“…As for the executive function, the ‘animal fluency test’, ‘repeat digits backward test’ and ‘take paper by your right hand’ in MMSE all showed lower scores in MCI-LB compared with MCI-AD. …”
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PAB-Mamba-YOLO: VSSM assists in YOLO for aggressive behavior detection among weaned piglets by Xue Xia, Ning Zhang, Zhibin Guan, Xin Chai, Shixin Ma, Xiujuan Chai, Tan Sun

“…This work is expected to contribute a glimmer of fresh ideas and inspiration to the research field of precision breeding and behavioral analysis of animals.…”
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Evaluation of hydrogel formulated with seaweed extract (Ulva lactuca) for incised wound healing in white rats (Rattus norvegicus) by Stephanie Taniwan, Refi Ikhtiari, Stephanie Taniwan, Fiska Maya Wardhani

“…Skin, as the largest organ in the human and animal body, serves as the main protection against various external factors such as sharp objects, extreme temperatures, chemicals, or physical trauma. …”
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Investigating the diagnostic accuracy of vertebral heart score, vertebral left atrium score and thoracic width measurement in cats with suspected cardiac problems by B. Ozdil, T. M. Parlak, M. Arican

“…Blood was drawn and Nt-proBNP concentrations were assayed in all animals. As a result, VHS was above the reference range in 14 cases. …”

Comparison and Economic Feasibility Study of The Productivity of Five Varieties of Barley (Hordeum vulgare L.) by Mahmod Karem Ahmad

“…In general, economic and agricultural policy of the successive Iraqi governments was not toward agricultural development and achieve food security, whether for humans or animals, for dependence on exports of oil to import country's food needs in a difficult currency, which cost the state budget amounts. …”
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Known and novel parvoviruses identified in domestic pigeons by Ewa Łukaszuk, Daria Dziewulska, Anthony Khalifeh, Joy M. Custer, Simona Kraberger, Arvind Varsani, Tomasz Stenzel

“…Abstract Background Parvoviridae is a family of single-stranded linear DNA viruses whose members infect both vertebrate and invertebrate species of animals, causing diseases of various systems and often associated with pathology of the gastrointestinal tract. …”
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Evaluating the antifibrotic potential of naringenin, asiatic acid, and icariin using murine and human precision‐cut liver slices by Ke Luo, Yana Geng, Dorenda Oosterhuis, Vincent E. deMeijer, Peter Olinga

“…These natural products have shown promise in animal models, but human data are lacking. In this study, PCLS prepared from male mouse liver tissue (mPCLS), healthy human liver tissue (hhPCLS), and cirrhotic human liver tissue (chPCLS) were cultured for 48 h with varying concentrations of the three compounds. …”
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High-Power, Computer-Controlled, Light-Emitting Diode–Based Light Sources for Fluorescence Imaging and Image-Guided Surgery by Sylvain Gioux, Vida Kianzad, Razvan Ciocan, Sunil Gupta, Rafiou Oketokoun, John V. Frangioni

“…Using this light source, we demonstrated NIR fluorescence–guided surgery in a large-animal model.…”
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A Combination of Coconut Fiber Suture and Tamarind Seed Gel with Dehydrated Human Amnion Membrane for Wound Surgery in Rats by Raghu Babu Pothireddy, Angeline Julius, Manu Thomas Mathai, Ganesh Lakshmanan, Beimnet Asfaw Hailemariam

“…This research signifies the use of TSP gel together with the amnion membrane representing a “smart patch” with wound healing potential, which would encourage further research on the smart patch made using a combination of plant and animal biological materials.…”
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TESTING OF EMULSION VACCINES BASED ON WHITE OILS OBTAINED AS A RESULT OF HYDROCATALYTIC PROCESSING OF OILSTOCK by I. V. Pigoleva, A. S. Sharypov, T. N. Shabalina, S. V. Zaglyadova, M. V. Kitova, S. A. Antonov, V. V. Mikhalishin, V. A. Starikov, D. V. Mikhalishin

“…Blood samples were taken from animals before vaccination and 14 days after it to obtain sera which were further tested for FMD antibodies using VNT. …”
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Melanocortin Peptide Therapy for the Treatment of Arthritic Pathologies by S. J. Getting, M. Kaneva, Y. Bhadresa, D. Renshaw, Giovanna Leoni, H. B. Patel, M. J. P. Kerrigan, I. C. Locke

“…The melanocortin peptides have been shown to display potent anti-inflammatory effects in both animal models of disease and patients. The potential anti-inflammatory role for endogenous peptides in arthritic pathologies is in its infancy. …”
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Semiautomatic Landmark-Based Two-Dimensional—Three-Dimensional Image Fusion in Living Mice: Correlation of Near-Infrared Fluorescence Imaging of Cy5.5-Labeled Antibodies with Flat-... by Christian Dullin, Marta Zientkowska, Joanna Napp, Jeannine Missbach-Guentner, Hans-Willi Krell, Friedemann Muller, Eckhardt Grabbe, Lutz-F. Tietze, Frauke Alves

“…For this purpose, mice were anesthetized and fixed on a multimodality animal bed containing fiducial markers filled with iodine-containing contrast agent and fluorescent dye. …”
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Application of Infrared Spectroscopy for Functional Compounds Evaluation in Olive Oil: A Current Snapshot by Sarfaraz Ahmed Mahesar, Massimo Lucarini, Alessandra Durazzo, Antonello Santini, Anja I. Lampe, Johannes Kiefer

“…In the last few decades, olive oil has received much attention as compared to the other seed-obtained oils as well as to the animal fats due to many functional compounds with positive effects on health. …”
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Modifying non-coding regions of linear DNA vaccines to explore the interplay of expression and inflammation in immunogenicity by David C. Stirling, Maria de Miguel Ferrer, Sungwon Kim, Madina Wane, Daniel Kysh, Lisa J. Caproni, John S. Tregoning

“…However, they have historically underperformed in large animals and human trials due to low immunogenicity. …”
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Comparing extraction conditions for favorable yield of lutein and zeaxanthin from distiller’s grains by Emily Aicher, Abigail S. Engelberth

“…In bioethanol production, distiller’s grains are a low-value byproduct stream that typically become animal feed. However, corn – and thus distiller’s grains – contains notable levels of lutein and zeaxanthin, carotenoids thought to play a role in maintaining eye health. …”
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Chronic Deep Brain Stimulation of the Hypothalamic Nucleus in Wistar Rats Alters Circulatory Levels of Corticosterone and Proinflammatory Cytokines by Juan Manuel Calleja-Castillo, Dora Luz De La Cruz-Aguilera, Joaquín Manjarrez, Marco Antonio Velasco-Velázquez, Gabriel Morales-Espinoza, Julia Moreno-Aguilar, Maria Eugenia Hernández, Lucinda Aguirre-Cruz, Lenin Pavón

“…DBS treated rats had higher levels of TNF-α (120%; P<0.01) and IFN-γ (305%; P<0.001) but lower corticosterone concentration (48%; P<0.001) than C and S. UCVgX animals showed increased corticosterone levels (154%; P<0.001) versus C and S. …”
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