Performance and limitations of linkage-disequilibrium-based methods for inferring the genomic landscape of recombination and detecting hotspots: a simulation study by Raynaud, Marie, Gagnaire, Pierre-Alexandre, Galtier, Nicolas

“…Such methods have been used in a broad range of plant and animal species to build genome-wide recombination maps. …”
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Russia-India Economic Cooperation: Current Trends and Promising Directions by Lydia Kulik

“…Nevertheless, the trade volume between Russia and India is now experiencing rapid growth due to the significant increase in exports of energy, fertilizers, iron and steel, wood products, vegetable and animal oils from Russia to India. This article not only examines this phenomenon but also assesses the necessary conditions to address India's escalating trade deficit with Russia. …”
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The Role of Yersinia enterocolitica O:3 Lipopolysaccharide in Collagen-Induced Arthritis by Katarzyna Kasperkiewicz, Anna S. Świerzko, Marta Przybyła, Janusz Szemraj, Jarosław Barski, Mikael Skurnik, Andrzej Kałużyński, Maciej Cedzyński

“…However, in contrast to the latter, Yersinia Rd1 LPS was associated neither with the adjuvancity nor with the enhancement of pathological changes in animal paws/impairment of motility. On the other hand, it seemed to be more hepatotoxic when compared with the other tested endotoxins, while the enlargement of inguinal lymph nodes and drop in hepatic MBL-C expression (at the mRNA level) were independent of LPS chemotype. …”
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Hemorrhagic Shock Induces a Rapid Transcriptomic Shift of the Immune Balance in Leukocytes after Experimental Multiple Injury by Lisa Debler, Annette Palmer, Sonja Braumüller, Bettina Klohs, Tom Eirik Mollnes, Karlheinz Holzmann, Markus Huber-Lang, Rebecca Halbgebauer

“…C57BL/6 mice were randomized into a control, PT, and PT + HS group with three animals in each group. Four hours after trauma, corresponding to three hours after induction of hemorrhage, RNA was isolated from all peripheral blood leukocytes, and a microarray analysis was performed. …”
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Transformation of History Learning in the Digital Era: Application of Riau Local History as an Interactive Educational Media by Septiani Chairul Nisa, Ajat Sudrajat, Ardian Fahri

“…The developed application, Riauxplore, integrates multimedia features such as videos, animations, and interactive quizzes to increase students’ interest in learning about local history. …”
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Cangfudaotan Decoction Alleviates Insulin Resistance and Improves Follicular Development in Rats with Polycystic Ovary Syndrome via IGF-1-PI3K/Akt-Bax/Bcl-2 Pathway by Chenye Wang, Caifei Ding, Zhoujia Hua, Chunyue Chen, Jia Yu

“…In this study, first, chemical components in CFD were clarified using UPLC-Q/TOF-MS analysis. Then, an animal model of PCOS was established, granular cells were also isolated from the rats with PCOS, and CFD was administrated at different dosages in PCOS rats and granular cells, to investigate the therapeutic effect and mechanisms of CFD for PCOS treatment. …”
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Drug delivery systems for oral cancer treatment: A patent perspective by Mohamed Hassan Dehghan, Abrar Abdul Malik Siddiqui

“…The review study shows assays like RT-PCR, immunohistochemistry, animal carcinoma models, and cytotoxicity tests to demonstrate anticancer efficacy. …”
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Increased Small Dense LDL and Decreased Paraoxonase Enzyme Activity Reveals Formation of an Atherogenic Risk in Streptozotocin-Induced Diabetic Guinea Pigs by Mutay Aslan, Filiz Ozcan, Ertan Kucuksayan

“…Guinea pigs were given a single intraperitoneal (ip) injection of streptozotocin (STZ) and animals having fasting blood glucose levels greater than 200 mg/dl, were considered diabetic. …”
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Impact of Edible Insect Polysaccharides on Mouse Gut Microbiota: A Study on White-Spotted Flower Chafer Larva (<i>Protaetia brevitarsis seulensis</i>) and Silkworm Pupa (<i>Bombyx... by Joon-Ha Lee, Hyojung Son, Sathiyamoorthy Subramaniyam, Hyun-Jung Lim, Sohyun Park, Ra-Yeong Choi, In-Woo Kim, Minchul Seo, Hae-Yong Kweon, Yongsoon Kim, Seong-Wan Kim, Jong-Soon Choi, Younhee Shin

“…In particular, <i>Lactococcus garvieae</i>, which has promising effects on the gastrointestinal tracts of humans and animals, was significantly enriched in both <i>Protaetia brevitarsis seulensis</i> larva and <i>Bombyx mori</i> pupa polysaccharides, similar to fracto-oligosaccharide. …”
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Sirtuin1 Targeting Reverses Innate and Adaptive Immune Tolerance in Septic Mice by Ayana N. Martin, Martha Alexander-Miller, Barbara K. Yoza, Vidula Vachharajani, Charles E. McCall

“…During sepsis, however, both strategies fail, and animal and human victims often die from combined innate and adaptive immune suppression with persistent bacterial and viral infections. …”
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Digital connection, real bonding: Brief online chats boost interpersonal closeness regardless of the conversational topic by Chiara Fini, Vanessa Era, Giovanna Cuomo, Ilenia Falcinelli, Mattia A. Gervasi, Matteo Candidi, Claudia Mazzuca, Marco Tullio Liuzza, Bodo Winter, Anna M. Borghi

“…., philosophical/spiritual, emotional, social, physical/spatio-temporal) and concrete topics (e.g., tools, animals, food). The results of the first experiment were replicated, reinforcing the idea that the quality of the virtual exchange—rather than the topic itself—plays a crucial role in fostering feelings of closeness between individuals.…”
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Ultrasonographic evaluation of the thorax in dogs with tick paralysis by Erdem Gülersoy, Canberk Balıkçı, İsmail Günal, Adem Şahan, Esma Kısmet

“…Thus, the aim of this study is to describe thoracic ultrasonography lesions in dogs with tick paralysis and to identify potential patterns that could aid in diagnosis and prognosis prediction. The animal material consisted of 58 dogs in total, 10 of which were healthy and 48 of which were suspected to be affected by tick paralysis. …”
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Prevalence and Antimicrobial Resistance of Escherichia coli in Chicken Meat and Edible Poultry Organs Collected from Retail Shops and Supermarkets of North Western Province in Sri... by R. A. S. S. Ranasinghe, D. A. Satharasinghe, P. S Anwarama, P. M. S. D. K. Parakatawella, L. J. P. A. P. Jayasooriya, R. M. S. B. K. Ranasinghe, R. P. V. J. Rajapakse, J. T. Y. Huat, Y. Rukayadi, Y. Nakaguchi, M. Nishibuchi, S. Radu, J. M. K. J. K. Premarathne

“…Escherichia coli is a commensal bacterium that lives in human and animal intestines. Shiga toxin-producing strains of E. coli STECs are responsible for most food-related E. coli infections. …”
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Lactic Acid Regulation: A Potential Therapeutic Option in Rheumatoid Arthritis by Qianlei Wang, James Asenso, Ning Xiao, Jinzhang Gao, Feng Xiao, Jiajie Kuai, Wei Wei, Chun Wang

“…Rapid energy supply depends on the anaerobic glucose metabolic pathway in both RA animal models and clinical patients. Anaerobic glycolysis can increase intracellular lactic acid (LA) content. …”
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Comparative Biochemical and Histopathological Studies on the Efficacy of Metformin and Virgin Olive Oil against Streptozotocin-Induced Diabetes in Sprague-Dawley Rats by Khadijah Saeed Balamash, Huda Mohammed Alkreathy, Elham Hamed Al Gahdali, Sawsan Omer Khoja, Aftab Ahmad

“…Thirty-six healthy male Sprague-Dawley rats were divided into six groups (6 rats per group) including nondiabetic control (NC), diabetic control (DC), and animals treated with metformin, olive oil, and a combination of olive oil and metformin, respectively. …”
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Ginger polysaccharide UGP1 suppressed human colon cancer growth via p53, Bax/Bcl-2, caspase-3 pathways and immunomodulation by Yanfang Qian, Chenying Shi, Chen Cheng, Dengwei Liao, Junping Liu, Gui-tang Chen

“…In this article, we aimed to illustrate the underlying mechanism of UGP1 exerted antitumor activities on colon cancer by using in vitro cell models and in vivo animal models. The results demonstrated that UGP1 could induce S-phase cell cycle arrest, up-regulate the expression of Bax and p53, down-regulate the expression of Bcl-2, and activate the downstream protein caspase-9 and caspase-3, which was related to intrinsic apoptosis pathway on HCT116 cells. …”
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Induced Hypothermia Does Not Harm Hemodynamics after Polytrauma: A Porcine Model by Matthias Weuster, Philipp Mommsen, Roman Pfeifer, Juliane Mohr, Steffen Ruchholtz, Sascha Flohé, Matthias Fröhlich, Claudia Keibl, Andreas Seekamp, Martijn van Griensven, Ingo Witte

“…Induced hypothermia had neither harmful nor major positive effects on the animals’ hemodynamics. Though heart rate significantly decreased and mixed venous oxygen saturation significantly increased during therapeutic hypothermia. …”
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Characterization of the Collagen Extraction Manufacturing Process Using Markov Chains and Artificial Neural Networks by Rosa Trasvina-Osorio, Sergio Alonso-Romero, Juan de Anda-Suarez, Valentin Calzada-Ledesma, Javier Yanez-Mendiola, Luis Fernando Villanueva-Jimenez, Erick Rojas-Mancera

“…This research aims to identify industrial applications for derivatives from animal by-products, such as tilapia skin, to develop an alternative methodology for issues related to collagen. …”
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Pharmacological evidence supporting a role for IL-1, IL-2 and serotonin in the inflammation induced by Schistosoma mansoni Soluble Egg Antigen (SEA) in rat paws by C. M. F. Pacheco, C. A. P. Tavares, P. M. Z. Coelho, O. A. Rocha, J. M. M. Santos, F. R. M. Prado, J. N. Francischi

“…The increased oedematogenic response derived from SEA-challenge (10 μg) of rat paws derived from a local rather than systemic reaction, since it was not observed if the sensitization was in the contralateral paw or the peritoneal cavity of the animals. Chronic tre atment with inhibitors of IL-2 synthesis / release such as cyclosporin or dexamethasone during the sens itization phase reduced the oedematogenic response due to SEA challenge by 51% and 55%, respectively. …”
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Histopathological studies upon effects of zeranol on the reproductive system in male merino lambs by M. Kemal ÇİFTÇİ, Metin Münir KIRAN

“…Each group consisted of 15 animals. Group I and group II were implanted with 12 mg zeranal subcutaneously the base of ear of lambs at the baginning of trials. …”
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