Dose and strain dependent lethality of Usutu virus in an Ifnar−/− mouse model by Johanna M. Duyvestyn, Eleanor M. Marshall, Peter J. Bredenbeek, Barry Rockx, Martijn J. van Hemert, Marjolein Kikkert

“…These results enhance our understanding of the pathogenicity of different USUV strains and provide guidance for the use of low doses for inoculation in an Ifnar−/− animal model.…”
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Conservation value and ecosystem service provision of Nothofagus antarctica forests based on phenocluster categories by Guillermo J. Martínez Pastur, Julián Rodríguez-Souilla, Yamina M. Rosas, Natalia Politi, Luis Rivera, Eduarda M. O. Silveira, Ashley M. Olah, Anna M. Pidgeon, María V. Lencinas, Pablo L. Peri

“…Conservation value and capacity to supply ES significantly varied among phenocluster categories: (i) cultural, regulating, and provisioning ES and potential biodiversity at landscape level, (ii) soil carbon and nitrogen, (iii) dominant height, crown cover, basal area, total volume, and domestic animal stock, and (iv) understory plant richness and cover at stand level. …”
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Negative Influence of a Long-Term High-Fat Diet on Murine Bone Architecture by Hinrich Fehrendt, Thomas Linn, Sonja Hartmann, Gabor Szalay, Christian Heiss, Reinhard Schnettler, Katrin Susanne Lips

“…Four-week-old male C57BL/6J mice received a high-fat diet (HFD, 60% kcal from fat) and were analyzed by means of dual X-ray absorptiometry, histological methods, real-time RT-PCR, and transmission electron microscopy in comparison to control animals (10% kcal from fat). The cancellous bone mass, collagen 1α1 expression, amount of osteoid, and cohesion of cells via cell-to-cell contacts decreased in HFD mice whereas the bone mineral density and the amount of osteoblasts and osteoclasts were not modified. …”
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The MMP-1/PAR-1 Axis Enhances Proliferation and Neuronal Differentiation of Adult Hippocampal Neural Progenitor Cells by Maria Maddalena Valente, Megan Allen, Valeria Bortolotto, Seung T. Lim, Katherine Conant, Mariagrazia Grilli

“…In complementary studies, we found that the percentage of Sox2+ undifferentiated progenitor cells is increased in hippocampi of MMP-1 tg animals, compared to wt mice. Together, these results add to a growing body of data suggesting that MMPs are effectors of hippocampal neuroplasticity in the adult CNS and that the MMP-1/PAR-1 axis may play a role in neurogenesis following physiological and/or pathological stimuli.…”
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Pi bon fason pou timoun piti (ki gen laj pou ale lekòl) lave men yo by Amy Simonne, Nicole Monval, Emmanuel Jean Claude Duvalsaint

“…Jèm ki bay maladi tankou larim, grip, dyare, ak vomisman ka vinn nan men w lè w manyen objè ki nan alantou w. Moun, animal domestik, manje kri, jwèt, tè, ak tout objè nou itilize plizyè fwa pa jou, yo tout ka gen jèm mikwòb sou yo. …”
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Injectable Chitosan Hydrogel Particles as Nasal Packing Materials After Endoscopic Sinus Surgery for Treatment of Chronic Sinusitis by Yusuke Yamashita, Kei Hosoya, Yukio Fujiwara, Yoichi Saito, Masahiro Yoshida, Shoji Matsune, Kimihiro Okubo, Takayuki Takei

“…In this study, we show in animal experiments that the chitosan hydrogel (hydrogel particles) had higher wound healing properties than a commercially available solid wound dressing (dry state) composed of the same polymer. …”
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Technique of Coaxial Frame in Reflection for the Characterization of Single and Multilayer Materials with Correction of Air Gap by Zarral Lamia, Djahli Farid, Ndagijimana Fabien

“…Techniques based on fixture probes in reflection are used in microwave reflectometry as a novel diagnostic tool for detection of skin cancers, for complex permittivity measurements on liquid samples and oil shale, and for complex dielectric permittivity of animals’ organs and tissues measurements in microwave band for the needs of modern veterinary medicine. …”
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The Protective Effect of Naringenin on Airway Remodeling after Mycoplasma Pneumoniae Infection by Inhibiting Autophagy-Mediated Lung Inflammation and Fibrosis by Yan Lin, Dan Tan, Qianna Kan, Zhen Xiao, Zhiyan Jiang

“…The results show proinflammatory cytokines (interleukin- [IL-] 6, IL-1β, and tumor necrosis factor-α), and transforming growth factor beta (TGF-β) expression was significantly increased after MP infection from both clinical and animal experiment. In vivo experimental confirmation showed that NRG treatment decreased MPP-induced lung injury in mice by inhibiting autophagy-mediated inflammatory cytokine expression and pulmonary fibrosis. …”
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Strategy and mechanism of One Health governance: case study of China by Xinchen Li, Yanyan Zhang, Qiyu Zhang, Jingshu Liu, Zelin Zhu, Xinyu Feng, Lefei Han, Xiaoxi Zhang

“…Background: Strategy and mechanism are crucial components of One Health governance in China, designed to address the interconnected health issues between humans, animals, and the environment. This study aims to evaluate China's current One Health governance framework, identify key strengths and gaps, and provide recommendations for establishing a more integrated and effective system. …”
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Phagocytosis by macrophages decreases the radiance of bioluminescent Staphylococcus aureus by Elles C. Boonstra, Liliana Agresti, Henny C. van der Mei, Paul C. Jutte, Jelmer Sjollema

“…Abstract Background In vivo evaluations of the antimicrobial efficacy of biomaterials often use bioluminescent imaging modalities based on bioluminescent bacteria to allow follow-up in single animals. Bioluminescence production by bacteria is dependent on their metabolic activity. …”
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Prevalence of hard ticks (acari: ixodidae) in spur-thighed tortoise (testudo graeca ibera) population of konya by Uğur Uslu, Muhammad Sohail Sajid, Onur Ceylan, Adil Ejaz

“…<b>Aim:</b>This study was carried out to determine the prevalence of ixodid tick species which play a role in the transmission of many diseases in humans and animals in spur-thighed tortoises.<p> <b>Materials and Methods:</b> Ticks were brought to the Laboratory of Parasitology by putting in sample collection bottles containing 70% ethanol and and were taxonomically identified was using standard keys.…”
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Phenolic extract from Ocimum basilicum restores lipid metabolism in Triton WR-1339-induced hyperlipidemic mice and prevents lipoprotein-rich plasma oxidation by Ilham Touiss, Saloua Khatib, Oussama Bekkouch, Souliman Amrani, Hicham Harnafi

“…The hypolipidemic activity was studied in mice model injected intraperitoneally with Triton WR-1339 at a dose of 200 mg/kg body weight. The animals were grouped as follows: normolipidemic control group (n = 8), hyperlipidemic control group (n = 8) and phenolic extract-treated group (n = 8) at a dose of 200 mg/kg body weight. …”
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Network pharmacology and experimental verification reveal the mechanism of Qingfei Tongluo mixture in treating pulmonary fibrosis by Ying Zhou, Wenlong Wang, Wanping Zhu, Tingting Cai, Nannan Wang, Xia Liu, Wenmin Wang, Kequn Chai

“…Immunohistochemistry showed elevated FTO and TGF-β1 levels in PF tissues. Animal experiments demonstrated that QTm improved alveolar structure, reduced interstitial lesions, and enhanced lung function while decreasing hydroxyproline content and the expression of FTO and TGF-β1 proteins. …”
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Restorative effects of camellia oil on the skin-barrier function in a model of DNCB-induced atopic dermatitis by Shicheng Jiao, Lijun Deng, Mu Niu, Jie Yang

“…A mouse model of AD was created via topical application of DNCB; subsequently, the animals were randomly divided into four groups: the blank control (Control), model (Model), moisturizing cream (Moisturizer), and camellia oil (Camellia) groups. …”
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Acute toxicity test combination of binahong leaves extract (Anredera cordifolia) and catfish oil (Pangasius micronema Blkr.) in mice by Rahma Shabrina Auliya, Meitasari Annisa Diyan, Sasongko Heru

“…The LD50 value in this study is a pseudo-LD50 because there is no death in all test animals. This shows that the combination of binahong extract and catfish oil is categorized as practically non-toxic with LD50 > 5000 mg/kg.…”
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Testicular and Related Size Evaluations in Nigerian Sahel Goats with Optimal Cauda Epididymal Sperm Reserve by Y. Abba, I. O. Igbokwe

“…Testicular sizes of animals are important for identification of those with adequate sperm production. …”
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Injectable supramolecular hydrogel co-loading abemaciclib/NLG919 for neoadjuvant immunotherapy of triple-negative breast cancer by Binyu Zhu, Ying Cai, Lingli Zhou, Lei Zhao, Jiameng Chen, Xiaoting Shan, Xujie Sun, Qian You, Xiang Gong, Wen Zhang, Helen He Zhu, Pengcheng Zhang, Yaping Li

“…The neoadjuvant immunotherapy reduces tumor recurrence and pulmonary metastasis and prolongs the survival of animals. This hydrogel provides a potential platform for neoadjuvant immunotherapy of triple-negative breast cancer with reduced toxicity compared with free abemaciclib.…”
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Secretion and signaling activities of lipoprotein-associated hedgehog and non-sterol-modified hedgehog in flies and mammals. by Wilhelm Palm, Marta M Swierczynska, Veena Kumari, Monika Ehrhart-Bornstein, Stefan R Bornstein, Suzanne Eaton

“…Hedgehog (Hh) proteins control animal development and tissue homeostasis. They activate gene expression by regulating processing, stability, and activation of Gli/Cubitus interruptus (Ci) transcription factors. …”
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Expanding Yarrowia lipolytica’s metabolic potential for detoxification of cyanogenic glycosides in edible plants by Fidelis Azi, Zhiyu Li, Peng Xu

“…The findings demonstrate that the strain is a robust, sustainable, and potentially efficient strain that could be used for industrial bioconversion of plant materials containing glycosylated toxicants into safe foods and animal feeds.…”
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Liver GlucokinaseA456V Induces Potent Hypoglycemia without Dyslipidemia through a Paradoxical Induction of the Catalytic Subunit of Glucose-6-Phosphatase by Anna Vidal-Alabró, Alícia G. Gómez-Valadés, Andrés Méndez-Lucas, Jordi Llorens, Ramon Bartrons, Jordi Bermúdez, Jose C. Perales

“…PEPCK mRNA was not affected, whereas the mRNA for the catalytic subunit of glucose-6-phosphatase was upregulated ~4 folds in the liver of GKA456V-treated animals, suggesting that glucose cycling was stimulated. …”
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