Using cortical organoids to understand the pathogenesis of malformations of cortical development by Kellen D. Winden, Isabel Gisser, Mustafa Sahin

“…One limitation is the difficulty in modeling these disorders, as animal models frequently do not faithfully mirror the human phenotype. …”
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Piezo1 promotes vibration-induced vascular smooth muscle injury by regulating the NF-κB/p65 axis by Yingshan Zeng, Zhiquan Wu, Mengtian Xiong, Zhishan Liang, Ziyu Chen, Huimin Huang, Hongyu Yang, Qingsong Chen

“…To mimic the effects of vibration, a rat vibration model and a cellular vibration model were used. Animal and cellular models showed that vibration-induced vascular dysfunction while increasing Piezo1 expression. …”
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High Serum Advanced Glycation End Products Are Associated with Decreased Insulin Secretion in Patients with Type 2 Diabetes: A Brief Report by Tsuyoshi Okura, Etsuko Ueta, Risa Nakamura, Yohei Fujioka, Keisuke Sumi, Kazuhisa Matsumoto, Kyoko Shoji, Kazuhiko Matsuzawa, Shoichiro Izawa, Yuri Nomi, Hitomi Mihara, Yuzuru Otsuka, Masahiko Kato, Shin-ichi Taniguchi, Kazuhiro Yamamoto

“…They directly cause insulin secretory defects in animal and cell culture models and may promote insulin resistance in nondiabetic subjects. …”
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Cultivable Actinobacteria First Found in Baikal Endemic Algae Is a New Source of Natural Products with Antibiotic Activity by Denis V. Axenov-Gribanov, Daria V. Kostka, Ulyana А. Vasilieva, Zhanna M. Shatilina, Maria E. Krasnova, Ekaterina V. Pereliaeva, Elena D. Zolotovskaya, Maria M. Morgunova, Olga O. Rusanovskaya, Maxim A. Timofeyev

“…Inadequate use of antibiotics has led to spread of microorganisms resistant to effective antimicrobial compounds for humans and animals. This study was aimed to isolate cultivable strains of actinobacteria associated with Baikal endemic alga Draparnaldioides baicalensis and estimate their antibiotic properties. …”
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Decrease of PPARδ in Type-1-Like Diabetic Rat for Higher Mortality after Spinal Cord Injury by Cheng-Chia Tsai, Kung-Shing Lee, Sheng-Hsien Chen, Li-Jen Chen, Keng-Fan Liu, Juei-Tang Cheng

“…Changes in the peroxisome proliferator-activated receptors-δ (PPARδ) expression in rats after spinal cord injury (SCI) have been previously reported. Diabetic animals show a higher mortality after SCI. However, the relationship between the progress of diabetes and PPARδ in SCI remains unknown. …”
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Dynamics of <i>Nakaseomyces glabratus</i> biofilm formation by E. M. Lenchenko, N. P. Sachivkina, A. V. Liseitsev

“…Formation of biofilms of microorganisms, including those of Nakaseomyces glabratus, is responsible for the development of local and systemic pathologies in humans and animals. The system of gene expression coordination (quorum sensing) in the representation of signaling molecules allows regulation of the amount and composition of biofilm populations thus expanding the adaptive capacity of microorganisms. …”
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Prenatal exposure to nitrate alters uterine morphology and gene expression in adult female F1 generation rats by André Gilberto Cassiani, Thiago Pinheiro Arrais Aloia, Érica Kássia Sousa-Vidal, Sérgio Podgaec, Carla de Azevedo Piccinato, Caroline Serrano-Nascimento

“…Previous studies have shown that nitrate disrupts the reproductive system in aquatic animals, but no study has evaluated the impact of nitrate exposure on the uterus in mammals. …”
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Muscarinic Receptors Types 1 and 2 in the Preoptic-Anterior Hypothalamic Areas Regulate Ovulation Unequally in the Rat Oestrous Cycle by Yadira L. López-Ramírez, Kayro López-Ramírez, Isabel Arrieta-Cruz, Angélica Flores, Luciano Mendoza-Garcés, Raúl A. Librado-Osorio, Roger Gutiérrez-Juárez, Roberto Domínguez, María Esther Cruz

“…The ovulation rate in rats treated with PZP on the oestrous day was lower than that in the vehicle group. Animals treated on dioestrous-1 with PZP or MTC had a higher ovulation rate than those in the vehicle group. …”
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Drosulfakinin signaling encodes early-life memory for adaptive social plasticity by Jiwon Jeong, Kujin Kwon, Terezia Klaudia Geisseova, Jongbin Lee, Taejoon Kwon, Chunghun Lim

“…Given the functional conservation of mammalian Dsk homologs, we propose that animals may have evolved a dedicated neural mechanism to encode early-life experience and transform group properties adaptively.…”
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Plant stem cells: unity and diversity by I. E. Dodueva, V. E. Tvorogova, M. Azarakhsh, M. A. Lebedeva, L. A. Lutova

“…In this review, we will consider the similarities and differences between the principles of organization of stem cell niches in plants and animals, as well as in a variety of meristems of higher plants; special attention will be paid to the role of WOX-CLAVATA systems in maintaining meristems and their interaction with other meristem regulators.…”
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Monitoring Disease Progression and Therapeutic Response in a Disseminated Tumor Model for Non-Hodgkin Lymphoma by Bioluminescence Imaging by Margarethe Köberle, Kristin Müller, Manja Kamprad, Friedemann Horn, Markus Scholz

“…We observed a close correlation of bioluminescence intensity and tumor burden, allowing us to monitor therapy response in the living animal. Cyclophosphamide reduced tumor burden in mice injected with either cell line in a dose-dependent manner. …”
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The Olive Oil Monophenolic Secoiridoid Ligstroside Aglycone Suppresses Melanoma Progression by Targeting the BRAF Signaling Pathway by Md Ashiq Mahmud, Abu Bakar Siddique, Afsana Tajmim, Judy Ann King, Khalid A. El Sayed

“…A Western blot analysis of the collected animal tumors further validated the downregulation of the mutated BRAF–MAPK axis, as well as the GPD1 and ELOVL6 expression levels. …”
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JTT-130, a Novel Intestine-Specific Inhibitor of Microsomal Triglyceride Transfer Protein, Improves Hyperglycemia and Dyslipidemia Independent of Suppression of Food Intake in Diab... by Shohei Sakata, Makoto Ito, Yasuko Mera, Tomohiko Sasase, Hiromi Yamamoto, Makoto Kakutani, Takeshi Ohta

“…We investigated the effects of JTT-130 on glucose and lipid metabolism independent of the suppression of feeding by comparing with pair-fed animals. Male Zucker diabetic fatty (ZDF) rats were divided into control, JTT-130 treatment, and pair-fed groups. …”
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Spectral Discrimination of Archaeological Sites Previously Occupied by Farming Communities Using In Situ Hyperspectral Data by Olaotse Lokwalo Thabeng, Elhadi Adam, Stefania Merlo

“…This study investigates the ability of field spectra measurements to discriminate between soils from non-sites (natural soils) and from archaeological sites, such as middens (rubbish-dumping areas) and animal byres. First, we tested whether there is a difference in the concentration of elements between different soil types using analysis of variance while random forest (RF) and forward variable selection (FVS) methods were used to select important soil elements for the classification of the archaeological sites. …”
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Exertional Myopathy in a Juvenile Green Sea Turtle (Chelonia mydas) Entangled in a Large Mesh Gillnet by Brianne E. Phillips, Sarah A. Cannizzo, Matthew H. Godfrey, Brian A. Stacy, Craig A. Harms

“…While histological changes in the examined muscle were modest, the acid-base, mineral, and electrolyte abnormalities were sufficiently severe to contribute to this animal’s mortality. Exertional myopathy in reptiles has not been well characterized. …”
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Pharmacological Evaluation of the SCID T Cell Transfer Model of Colitis: As a Model of Crohn's Disease by Thomas Lindebo Holm, Steen Seier Poulsen, Helle Markholst, Stine Reedtz-Runge

“…Animal models are important tools in the development of new drug candidates against the inflammatory bowel diseases (IBDs) Crohn's disease and ulcerative colitis. …”
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Timing of dietary effects on the epigenome and their potential protective effects against toxins by Lynnea A. Nicholls, Kendall A. Zeile, London D. Scotto, Rebecca J. Ryznar

“…Numerous studies in humans and animals suggest that diet has the potential to modify the epigenome and these modifications can be inherited transgenerationally, but few studies investigate how diet can protect against negative effects of toxins. …”
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Étude ethnotaxonomique des espèces fruitières spontanées comestibles chez l’ethnie Diola d’Oussouye (Sénégal) by Yves Djihounouck, Doudou Diop, César Bassène, Mame Samba Mbaye, Richard Demba Diop, Babacar Faye, Kandioura Noba

“…In addition 7 tables reference are mentioned and order of importance are : use, animal, morphology, ecology onomatopoeia and metaphor. …”
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Evaluation in terms of various parameters the selçuk university faculty of veterinary medicine graduates opinions by Aşkın Yaşar, Gökhan Aslım, Mehmet Emin Tekin, Mustafa Bahadır Çevrimli, Burak Mat, Mustafa Agah Tekindal

“…<p> <b>Conclusion:</b> Selçuk University Faculty of Veterinary Medicine has made significant contributions to the animal husbandry in almost all industry of the profession since its establishment. …”
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In vivo MRI visualization of growth and morphology in the orthotopic xenotrasplantation U87 glioblastoma mouse SCID model by E. L. Zavjalov, I. A. Razumov, L. A. Gerlinskaya, A. V. Romashchenko

“…The study of tumor formation and the evaluation of new therapies for GBM require accurate and reproducible experimental brain tumor animal models. In this study we used MRI for investigation of tumor morphology and growth dynamic in an orthopic xenotransplantation immunodeficient mouse model (SCID mouse line). …”
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