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  1. 9161

    Neuroplasticity of Acupuncture for Stroke: An Evidence-Based Review of MRI by Jinhuan Zhang, Chunjian Lu, Xiaoxiong Wu, Dehui Nie, Haibo Yu

    Published 2021-01-01
    “…After searching PubMed, Web of Science, and Embase databases, 24 human and five animal studies were identified. This review focuses on the evidence on the possible mechanisms underlying mechanisms of acupuncture therapy in treating stroke by regulating brain plasticity. …”
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  2. 9162

    Effect of Transplantation of Bone Marrow Derived Mesenchymal Stem Cells and Platelets Rich Plasma on Experimental Model of Radiation Induced Oral Mucosal Injury in Albino Rats by Basma Elsaadany, Samar El Kholy, Dalia El Rouby, Laila Rashed, Tarek Shouman

    Published 2017-01-01
    “…Twelve rats served as control group (N) and 48 rats received a single radiation dose of 13 Gy to the head and neck region; then, they were equally divided into 4 experimental groups: irradiated only (C), irradiated + MSCs (S), irradiated + (PRP) (P), and combined group (PS). Animal scarification occurred in 3 and 7 days after radiation. …”
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  3. 9163

    Single-cell sequencing elucidates the mechanism of NUSAP1 in glioma and its diagnostic and prognostic significance by Meng-Yu Zhao, Zhao-Lei Shen, Hongzhen Dai, Wan-Yan Xu, Li-Na Wang, Yu- Gu, Jie-Hui Zhao, Tian-Hang Yu, Cun-Zhi Wang, Jia-feng Xu, Guan-Jun Chen, Dong-Hui Chen, Wen-Ming Hong, Wen-Ming Hong, Fang Zhang

    Published 2025-02-01
    “…We found that elevated NUSAP1 expression correlated with poor prognosis, prompting further investigation of its functional role through both cellular and animal studies.ConclusionsNUSAP1-based risk models hold potential as predictive and therapeutic tools for personalized glioma treatment. …”
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  4. 9164

    From Scientific Research to Geoconservation and Geopark by Dan Grigorescu

    Published 2020-11-01
    “…The region illustrates the phenomenon of “insular dwarfism”, linked to the lengthy persistence of animals in isolated habitats. Palaeontological research in the region took place across two periods, separated by a 50-year gap in which no systematic studies were carried out. …”
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  5. 9165

    Advances in liver organoids: replicating hepatic complexity for toxicity assessment and disease modeling by Weidong Shao, Hui Xu, Kanghua Zeng, Mingzhou Ye, Renjun Pei, Kai Wang

    Published 2025-01-01
    “…Traditional cellular and animal models, while widely used, have significant limitations in replicating the liver’s complex responses to various stressors. …”
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  6. 9166

    Nutritional cardiomyopathy in a young camel (c. dromedarius) by Özgür Özdemir, Mustafa Kemal Çiftçi, Fatih Hatipoğlu, Mustafa Ortatatlı, Orhan Yavuz, Özgür Kanat

    “…So, it is advisable to have a vitamin and mineral supplement to animal especially within the enclosed areas like zoos.…”
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  7. 9167

    From Serendipity to Precision: Integrating AI, Multi-Omics, and Human-Specific Models for Personalized Neuropsychiatric Care by Masaru Tanaka

    Published 2025-01-01
    “…Despite these advancements, traditional methodologies such as animal models and single-variable analyses continue to be used, frequently failing to capture the complexities of human neuropsychiatric conditions. …”
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  8. 9168

    Wisdom of Landscape Construction of China’s West Lakes in Historical Period and Its Implications by Lyuyuan Jia, Qing Lin, Xiyue Wang, Wenzhen Jia, Ying Zhao, Zhiqing Zhang, Ziqi Cui, Song Chen, Aibo Jin

    Published 2024-12-01
    “…The results indicate the following: (1) The overall spatial distribution of WLs is related to China’s history of water conservancy development. (2) The evolution of and functional changes in WLs are influenced by multiple factors such as politics, economy, and culture during different historical periods and are directly related to the will of local administrators. (3) The initial functions of WLs can be categorized into three types, primarily related to urban infrastructure. (4) In terms of spatial relationships, there are four types of spatial relationships between WLs and their water sources and three types of spatial relationships between WLs and cities, forming a common pattern of “Mountains/Hills(–Water)–WL(–Water)–Cities(–Water, River, Sea)” or “WL(–Water)–Cities(–Water, River, Sea)”. (5) The scenery of WLs comprises six elements, including natural basements, water conservancy facilities, human settlements, secularization, landscape architecture, and animal and human activities, all imbued with poetic cultural connotations. …”
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  9. 9169

    Quantitative Proteomic Analysis of Hepatic Tissue of T2DM Rhesus Macaque by Tingfu Du, Shuaiyao Lu, Qinfang Jiang, Yun Li, Kaili Ma

    Published 2017-01-01
    “…The high-fat/high-sucrose diets combined with streptozotocin- (STZ-) induced nonhuman primate animal model of diabetes are a valuable research source of T2DM. …”
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  10. 9170

    Planes de vacunación en animales de compañía y sistemas de producción en equinos y bovinos by Adriana Michelle García-Meneses, Angie Nikole Cruz-Peña, Dumar Jaramillo Hernández

    Published 2024-08-01
    “…En equinos es profiláctica para la encefalomielitis y la influenza equina, pudiendo evitar el sufrimiento del animal y las posibles pérdidas económicas; mientras que, en producción bovina puede ser altamente preventiva contra afecciones como brucelosis y fiebre aftosa, las cuales pueden tener consecuencias económicas graves en la industria. …”
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  11. 9171

    Comparative Evaluation of Bone Repair with Four Different Bone Substitutes in Critical Size Defects by Gustavo Grossi-Oliveira, Leonardo P. Faverani, Bruno Coelho Mendes, Tárik Ocon Braga Polo, Gabriel Cury Batista Mendes, Valthierre Nunes de Lima, Paulo Domingos Ribeiro Júnior, Roberta Okamoto, Osvaldo Magro-Filho

    Published 2020-01-01
    “…For this, 24 male Albino rabbits were submitted to the creation of a bilateral 8 mm calvarial bone defect. The animals were divided into four groups—bovine hydroxyapatite, Bio-Oss® (BIO); Lumina-Bone Porous® (LBP); Bonefill® (BFL); and an alloplastic material, Clonos® (CLN)—and were euthanized at 14 and 40 days. …”
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  12. 9172

    Impact of Bifidobacterium longum NSP001 on DSS-induced colitis in conventional and humanised mice by Menglin Chen, Hong Yao, Huizi Tan, Wenqi Huang, Quanyong Wu, Shaoping Nie

    Published 2023-07-01
    “…However, differences between human and animal microbiota may confound the data reproducibility from rodent experiments to clinical trials. …”
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  13. 9173

    Study of information needs of students in the field of environmental policy by I. D. Porfirieva

    Published 2018-12-01
    “…The thoughtless, unlimited satisfaction of the growing needs of people has led to an irreversible change in the properties of landscapes, the depletion and loss of minerals, the disappearance of many species of the animal and plant world. Unsolved problems in the field of ecology, at the moment, reflect the reality of the twenty-first century. …”
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  14. 9174

    Toll-Like Receptor 4 in Bone Marrow-Derived Cells Contributes to the Progression of Diabetic Retinopathy by Hui Wang, Haojun Shi, Jing Zhang, Guoliang Wang, Jinxiang Zhang, Fagang Jiang, Qing Xiao

    Published 2014-01-01
    “…To further elucidate the mechanism of DR, we used bone marrow transplantation to establish reciprocal chimeric animals of TLR4 mutant mice and TLR4 WT mice combined with diabetes mellitus (DM) induction by streptozotocin (STZ) treatment to identify the role of TLR4 in different cell types in the development of the proinflammatory state during DR. …”
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  15. 9175

    Deficient Autophagy in Microglia Aggravates Repeated Social Defeat Stress-Induced Social Avoidance by Mai Sakai, Zhiqian Yu, Ryo Hirayama, Masa Nakasato, Yoshie Kikuchi, Chiaki Ono, Hiroshi Komatsu, Miharu Nakanishi, Hatsumi Yoshii, David Stellwagen, Tomoyuki Furuyashiki, Masaaki Komatsu, Hiroaki Tomita

    Published 2022-01-01
    “…We found that RSD stress, an animal model of MDD, significantly induced initial autophagic signals followed by increased transcription of autophagy-related genes (Atg6, Atg7, and Atg12) in the PFC. …”
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  16. 9176

    Differential Micronuclei Induction in Human Lymphocyte Cultures by Imidacloprid in the Presence of Potassium Nitrate by Polychronis Stivaktakis, Dimitris Vlastos, Evangelos Giannakopoulos, Demetrious P. Matthopoulos

    Published 2010-01-01
    “…Humans are exposed to pesticides as a consequence of their application in farming or their persistence in a variety of media, including food, water, air, soil, plants, animals, and smoke. The interaction of pesticides with environmental factors may result in the alteration of their physicochemical properties. …”
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  17. 9177

    Inhibition of mutagenic activation of orthoaminoazotoluene increases its carcinogenicity for mouse liver by V. I. Kaledin, L. P. Ovchinnikova, S. I. Ilnitskaya, T. S. Morozkova, N. A. Popova

    Published 2016-12-01
    “…Various mutationally impaired genes are often found in malignant tumors of animals and humans. At the same time, a large number of carcinogens demonstrate positive activity in different in vitro tests for mutagenicity. …”
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  18. 9178

    Major royal-jelly proteins intake modulates immune functions and gut microbiota in mice by Hang Wu, Shican Zhou, Wenjuan Ning, Xiao Wu, Xiaoxiao Xu, Zejin Liu, Wenhua Liu, Kun Liu, Lirong Shen, Junpeng Wang

    Published 2024-01-01
    “…The production of IL-1β, IL-6, and IFN-γ was negatively associated with estrogen levels, which were higher in the MRJP-treated animals than in the control group. Analysis of the gut microbiota revealed that feeding mice 250 mg/kg of MRJPs maintained the stability of the natural intestinal microflora of mice. …”
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  19. 9179

    Potential Use of Euphorbia hirta for Dengue: A Systematic Review of Scientific Evidence by Sashini D. Perera, Uthpala A. Jayawardena, Chanika D. Jayasinghe

    Published 2018-01-01
    “…Eight full papers were entitled to the review; out of those, two studies focused on ethnobotanical surveys, three on animal experiments, one on human trial, and two on in vitro antiviral activities, and one was computational study. …”
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  20. 9180

    Maresin 1 Mitigates Inflammatory Response and Protects Mice from Sepsis by Ruidong Li, Yaxin Wang, Zhijun Ma, Muyuan Ma, Di Wang, Gengchen Xie, Yuping Yin, Peng Zhang, Kaixiong Tao

    Published 2016-01-01
    “…Maresin 1 (Mar1) is a new proresolving mediator with potent anti-inflammatory effect in several animal models. However, its effect in sepsis is still not investigated. …”
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