Patient-Specific Pluripotent Stem Cells in Neurological Diseases by Serpen Durnaoglu, Sermin Genc, Kursad Genc

“…However, iPSC-based therapeutic strategies need to be thoroughly evaluated in preclinical animal models of neurological diseases before they can be applied in a clinical setting.…”
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Pathological Microenvironment‐Remodeling Nanoparticles to Alleviate Liver Fibrosis: Reversing Hepatocytes‐Hepatic Stellate Cells Malignant Crosstalk by Ling‐Feng Zhang, Wen‐Qi Deng, Xing‐Huan Wang, Qing‐Wen Huang, Su‐Qing Liang, Ze‐Quan Ding, Liang Qi, Yi Wang, Tian‐Jiao Zhou, Lei Xing, Jai‐Woo Lee, Yu‐Kyoung Oh, Hu‐Lin Jiang

“…The C‐NPs/BT shows successful remodeling of vicious cellular crosstalk and significant disease regression in animal models. This study presents an innovative strategy to modulate cellular interactions for enhanced anti‐fibrotic therapy and suggests a promising approach for treating other chronic liver diseases.…”
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First records of egg phoretic flies of Dermatobia hominis (Linnaeus, 1781) (Diptera: Cuterebridae) in Ecuador by Alex Pazmiño-Palomino, Cristhian Cusicondor-Loza

“…Knowing and monitoring the phoretic flies of D. hominis eggs is a part of myiasis control to avoid long-term economic losses in animal production. Samples were collected with hand nets and Malaise traps at five localities in the Pacific slopes of the Andes and four on the Amazonian slopes. …”
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Rabbits, Rabbits, Rabbits: Show Rabbit Record Book by Joy C. Jordan, Loretta Rodriguez, Jessica Kochert, Bill Heltemes, Chris Decubellis, Renee Gore

“…Records help youth keep track of vital information that can later help them make the best decisions regarding their animals. By tracking inventory, financial records associated with their project, rabbit health and growth details, industry-specific information such as wool/meat/kit yield, as well as pedigree/breeding and identification methods and dates, youth will be well prepared to relate their experiences in a written narrative as part of their project completion activities. …”
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Optimal Design of Grid-Connected Solar Photovoltaic System Using Selective Particle Swarm Optimization by Habtemariam Aberie Kefale, Elias Mandefro Getie, Kassaye Gizaw Eshetie

“…The interruption of power is due to overloading and failure of distribution lines due to external forces, like trees, animals, and wind. The failure of the radial distribution network brings blackout in the whole power system network as there is no alternative electricity supply. …”
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Les migrations dans les mondes alpin et jurassien suisses du Moyen Age au milieu du XXe siècle : un bref survol by Anne-Lise Head-König

“…The mobility of part of the population was also a consequence of modifications deriving from changes in the prevalent type of production (animal husbandry instead of the cultivation of cereals), as well as from demographic factors. …”
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Use of Autologous Mesenchymal Stem Cells Derived from Bone Marrow for the Treatment of Naturally Injured Spinal Cord in Dogs by Euler Moraes Penha, Cássio Santana Meira, Elisalva Teixeira Guimarães, Marcus Vinícius Pinheiro Mendonça, Faye Alice Gravely, Cláudia Maria Bahia Pinheiro, Taiana Maria Bahia Pinheiro, Stella Maria Barrouin-Melo, Ricardo Ribeiro-dos-Santos, Milena Botelho Pereira Soares

“…Cell suspensions were prepared and surgically administered into the spinal cord. The animals were clinically evaluated and examined by nuclear magnetic resonance. …”
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Central Role of Gimap5 in Maintaining Peripheral Tolerance and T Cell Homeostasis in the Gut by Mehari Endale, H. Ibrahim Aksoylar, Kasper Hoebe

“…In addition, the generation of “IBD-prone” animal models using both reverse and forward genetic approaches has not only helped confirm the identification of susceptibility loci but also shed critical insight into the underlying molecular and cellular pathways that drive colitis development. …”
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Precision nanoparticles for drug delivery, cell therapy tracking, and theranostics by Felder-Flesch, Delphine, Talamini, Laura, Muller, Sylviane

“…Certain dangers or fears regarding their use in human and animal therapy or for users have been mentioned. Finally, conclusions and future perspectives are provided.…”
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Gingival Mesenchymal Stem/Progenitor Cells: A Unique Tissue Engineering Gem by Karim M. Fawzy El-Sayed, Christof E. Dörfer

“…The review further demonstrates their immunomodulatory properties, the transplantation preconditioning attempts via multiple biomolecules to enhance their attributes, and the experimental therapeutic applications conducted to treat multiple diseases in experimental animal models in vivo. G-MSCs show remarkable tissue reparative/regenerative potential, noteworthy immunomodulatory properties, and primary experimental therapeutic applications of G-MSCs are very promising, pointing at future biologically based therapeutic techniques, being potentially superior to conventional clinical treatment modalities.…”
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Curcumin Alters Neural Plasticity and Viability of Intact Hippocampal Circuits and Attenuates Behavioral Despair and COX-2 Expression in Chronically Stressed Rats by Ga-Young Choi, Hyun-Bum Kim, Eun-Sang Hwang, Seok Lee, Min-Ji Kim, Ji-Young Choi, Sung-Ok Lee, Sang-Seong Kim, Ji-Ho Park

“…It also recovered the behavior immobility of FST, rescued the attenuated BDNF expression, and inhibited the enhancement of COX-2 expression in stressed animals. These findings indicate that curcumin can enhance postsynaptic electrical reactivity and cell viability in intact neural circuits with antidepressant-like effects, possibly through the upregulation of BDNF and reduction of inflammatory factors in the brain.…”
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Evaluation of the immunological functions of placental alkaline phosphatase in vivo using ALPP transgenic mice by Tse-Ching Chen, Kwai-Fong Ng, Ning Chen, Yi-Ling Pan, Chun-An Cheng, Hsiao-Chun Wu, Yi-Jen Hsueh, Nien-Yi Chiang, Hsi-Hsien Lin, Hsi-Hsien Lin, Hsi-Hsien Lin, Hsi-Hsien Lin

“…Our results showed that ALPP transgenic mice are more susceptible to intraperitoneal injection of LPS in comparison to control animals. In addition, female ALPP transgenic mice were better at delaying the rejection of male skin grafts. …”
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PCL/PHBV Microparticles as Innovative Carriers for Oral Controlled Release of Manidipine Dihydrochloride by Fernanda Malaquias Barboza, Willian Moreira Machado, Luiz Renato Olchanheski Junior, Josiane Padilha de Paula, Sônia Faria Zawadzki, Daniel Fernandes, Paulo Vitor Farago

“…In vitro dissolution studies showed that all microparticles prolonged MAN release, mainly which one obtained using PCL that contained 5% of drug loaded (PCL-M5). Animal studies demonstrated that formulation PCL-M5 was able to keep the variation of mean arterial pressure after phenylephrine administration up to 24 hours. …”
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The Effect of High Intensity Focused Ultrasound Keratoplasty on Rabbit Anterior Segment by Menglei Wang, Meixuan Li, Pisong Yan, Qiang Luo, Yu Zhang, Zhiyu Du

“…The right corneas of 36 New Zealand rabbits were treated with HIFU keratoplasty. The animals were sacrificed at 1, 7, 15, 30, 60, and 90 days after operation. …”
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COMPARATIVE CLIMATIC CHARACTERISTICS BETWEEN THE WINTER OF 2011–2012 AND THE WINTER OF 1953–1954 IN THE SOUTH OF ROMANIA by ION MARINICĂ, ANDREEA FLORIANA MARINICĂ, OCTAVIA BOGDAN

“…National losses: disrupted traffic of all types, snow-blocked households and animal shelters, black-outs, closed schools,difficulties in conducting supply and salvage operations for the population, etc. …”
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Application of a Plug-and-Play Immunogenicity Assay in Cynomolgus Monkey Serum for ADCs at Early Stages of Drug Development by Montserrat Carrasco-Triguero, Helen Davis, Yuda Zhu, Daniel Coleman, Denise Nazzal, Paul Vu, Surinder Kaur

“…Secondly, we propose a cut point methodology based on animal specific baseline variability instead of a population data approach. …”
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Facultative parthenogenesis: a transient state in transitions between sex and obligate asexuality in stick insects? by Larose, Chloé, Lavanchy, Guillaume, Freitas, Susana, Parker, Darren J., Schwander, Tanja

“…Such a trade-off could help explain why facultative parthenogenesis is rare among animals, despite its potential to combine the known benefits of sex and parthenogenesis. …”
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Expériences paysagères et pratique du ski de randonnée dans les Alpes françaises by Stéphane Marpot, Laine Chanteloup, Clémence Perrin-Malterre

“…This landscape experience will challenge a vision-centric definition of the landscape in order to apprehend the landscape as determined by human perception and, above all, as determined by the relationships formed and materialised between existing elements (animals, plants, abiotic elements). Far from a passive contemplation in which only vision is predominant, "making beautiful or fine traces" entirely engages the practitioners in a physical capacity. …”
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Effect of SIS3 on Extracellular Matrix Remodeling and Repair in a Lipopolysaccharide-Induced ARDS Rat Model by Qiong Liang, Qiqing Lin, Yueyong Li, Weigui Luo, Xia Huang, Yujie Jiang, Chunyan Qin, Jin Nong, Xiang Chen, Suren Rao Sooranna, Liao Pinhu

“…A selective inhibitor of Smad3 (SIS3) was intraperitoneally injected into the disease model, while phosphate-buffered saline (PBS) was used in the control group. Animal tissues were then evaluated using histological analysis, immunohistochemistry, RT-qPCR, ELISA, and western blotting. …”
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Feasibility of Novel Magnetically Controlled Cable Capsule Endoscopy System In Vitro Experiments for Gastric Examination by Yaoping Zhang, Lina Qu, Yani Gou, Jinyong Hao, Xiaojun Huang

“…MCCCE system is feasible for gastric examination in vitro experiments, living animal experiments and human trials need to be further conducted.…”
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