Rwandan Farmers’ Perceptions of the Acoustic Environment and the Potential for Acoustic Monitoring by Destiny Kwabla Amenyedzi, Micheline Kazeneza, Frederic Nzanywayingoma, Philibert Nsengiyumva, Peace Bamurigire, Emmanuel Ndashimye, Anthony Vodacek

“…Farmers have a clear priority to listen to animals on the farm, whether they are pests (specifically, birds) or livestock. …”
Get full text

The Anthelmintic Effect of Pumpkin Seed (Cucurbita moschata Durch) Infusion on Lethal Death Time of Fasciola giganticaIn Vitro by Andriani Dwi Siswarini, Kusnoto Kusnoto, Retno Bijanti

“…Fasciola gigantica is a worm which could infect breeding animal and human. One of the plants that can be used as worm drug is Pumpkin seed (Cucurbita moschata Durch).Pumpkin seed (Cucurbita moschata Durch) has been used in traditional anthelmintic medicine. …”
Get full text

Diabetes Downregulates Allergen-Induced Airway Inflammation in Mice by Vinicius F. Carvalho, Emiliano O. Barreto, Ana Carolina S. Arantes, Magda F. Serra, Tatiana Paula T. Ferreira, Yago A. P. Jannini-Sá, Cory M. Hogaboam, Marco A. Martins, Patrícia M. R. Silva

“…Diabetes was induced by intravenous injection of alloxan into 12 h-fasted A/J mice, followed by subcutaneous sensitization with ovalbumin (OVA) and aluminum hydroxide (Al(OH)3), on days 5 and 19 after diabetes induction. Animals were intranasally challenged with OVA (25 μg), from day 24 to day 26. …”
Get full text

Histopathological, Immunohistochemical and Biochemical Studies of Murine Hepatosplenic Tissues Affected by Chronic Toxoplasmosis by Samah Hassan Yahia, Samia Elsayed Etewa, Nesreen Saeed Saleh, Samira Metwally Mohammad, Nora Ibrahim Aboulfotouh, Ahmad Mansour Kandil, Mohamed Hassan Sarhan

“…Toxoplasmosis is a serious health problem in humans and animals resulting from obligatory intracellular invasion of reticuloendothelial tissue by Toxoplasma gondii. …”
Get full text

Effects of hyaluronic acid on bone graft healing: An experimental study on sheep. by Muhmmed Ahmed Mustafa, Othman A. Omar

“…The samples then sacrificed in deferent period interval 2 weeks, 6 weeks and 12 weeks and the sample collected and sent for histological examination. Results: all animals survived till the end of study. Both groups were characterized by new bone formation in defects however the bone formation in group 1 significantly preceded. …”
Get full text

Hydrogen-Rich Saline Inhibits NLRP3 Inflammasome Activation and Attenuates Experimental Acute Pancreatitis in Mice by Jian-Dong Ren, Jie Ma, Jun Hou, Wen-Jin Xiao, Wei-Hua Jin, Juan Wu, Kai-Hua Fan

“…Hydrogen-rich saline (HRS), a well-known ROS scavenger, has been shown to possess therapeutic benefit on AP in many animal experiments. Recent findings have indicated that the NOD-like receptor family, pyrin domain-containing 3 (NLRP3) inflammasome, an intracellular multiprotein complex required for the maturation of interleukin- (IL-) 1β, may probably be a potential target of HRS in the treatment of AP. …”
Get full text

The Potential for Cellular Therapy Combined with Growth Factors in Spinal Cord Injury by Jack Rosner, Pablo Avalos, Frank Acosta, John Liu, Doniel Drazin

“…Therapies that show promise in small animal models may not transfer to nonhuman primates and humans. …”
Get full text

Untargeted metabolomic and proteomic analysis implicates SIRT2 as a novel therapeutic target for diabetic nephropathy by Ruijing Zhang, Runze Chang, Heng Wang, Jinshan Chen, Chuanlong Lu, Keyi Fan, Yuhang Zhang, Lizheng Li, Sheng Yan, Honglin Dong

“…The serum of 10 patients who were diagnosed with DN and 10 healthy individuals via untargeted metabolomics and Olink proteomics. Animal models were used to validate the characterized genes. …”
Get full text

4-Methoxycarbonyl Curcumin: A Unique Inhibitor of Both Inflammatory Mediators and Periodontal Inflammation by Ying Gu, Hsi-Ming Lee, Nicole Napolitano, McKenzie Clemens, Yazhou Zhang, Timo Sorsa, Yu Zhang, Francis Johnson, Lorne M. Golub

“…In the current study, we demonstrate that a novel CMC (CMC 2.5: 4-methoxycarbonyl curcumin) has significant inhibitory effects, better than the parent compound curcumin, on proinflammatory cytokines and MMPs in in vitro, in cell culture, and in an animal model of periodontal inflammation. The therapeutic potential of CMC 2.5 and its congeners may help to prevent tissue damage during various chronic inflammatory diseases including periodontitis and may reduce the risks of systemic diseases associated with this local disorder.…”
Get full text

Population Genomics Reveals Elevated Inbreeding and Accumulation of Deleterious Mutations in White Raccoon Dogs by Yinping Tian, Yu Lin, Yue Ma, Jiayi Li, Sunil Kumar Sahu, Jiale Fan, Chen Lin, Zhiang Li, Minhui Shi, Fengping He, Lianduo Bai, Yuan Fu, Zhangwen Deng, Huabing Guo, Haimeng Li, Qiye Li, Yanchun Xu, Tianming Lan, Zhijun Hou, Yanling Xia, Shuhui Yang

“…The formation of animal breeds usually begins with a small subsample from their ancestral population. …”
Get full text

Targeting HIF-1α to Prevent Renal Ischemia-Reperfusion Injury: Does It Work? by Kapil Sethi, Kenny Rao, Damien Bolton, Oneel Patel, Joseph Ischia

“…While many promising chemical agents have been trialed for the prevention of IRI in small animal studies, all have failed in human trials. The aim of this review is to highlight the techniques and drugs that target HIF-1α and ameliorate IRI associated with renal ischemia. …”
Get full text

Ensete ventricosum: A Multipurpose Crop against Hunger in Ethiopia by Getahun Yemata

“…It has an irreplaceable role as a feed for animals. Enset starch is found to have higher or comparable quality to potato and maize starch and widely used as a tablet binder and disintegrant and also in pharmaceutical gelling, drug loading, and release processes. …”
Get full text

Optimisation of Dairy Soiled Water as a Novel Duckweed Growth Medium by Cian Redmond, Neil E. Coughlan, Aine Purcell, Marcel A. K. Jansen

“…Under the principles of circular economy, duckweed-based valorisation of DSWs can lead to the production of valuable, high-protein plant biomass that could be incorporated into animal feed to support livestock nutritional requirements. …”
Get full text

Optimal Analysis Method for Dynamic Contrast-Enhanced Diffuse Optical Tomography by Michael Ghijsen, Yuting Lin, Mitchell Hsing, Orhan Nalcioglu, Gultekin Gulsen

“…In this study, we investigated and compared different reconstruction methods and analysis approaches for regular endogenous DOT and DCE-DOT with and without MR anatomical a priori information for arbitrarily-shaped objects. Our phantom and animal studies have shown that superior image quality and higher accuracy can be achieved using DCE-DOT together with MR structural a priori information. …”
Get full text

Development of a Dynamic Virtual Reality Model of the Inner Ear Sensory System as a Learning and Demonstrating Tool by P. Selva, J. Morlier, Y. Gourinat

“…This model, implemented in MATLAB/Simulink, simulates the rotary chair testing which is one of the tests carried out during a diagnosis of the vestibular system. High-quality 3D animations linked to the Simulink model are created using the export of CAD models into Virtual Reality Modeling Language (VRML) files. …”
Get full text

The Role of TLR2, TLR4, and TLR9 in the Pathogenesis of Atherosclerosis by Mohsin H. K. Roshan, Amos Tambo, Nikolai P. Pace

“…This review outlines the pathophysiological role of TLR2, TLR4, and TLR9 in atherosclerosis, focusing on evidence from animal models of the disease.…”
Get full text

Correlation of Circulating Acid-Labile Subunit Levels with Insulin Sensitivity and Serum LDL Cholesterol in Patients with Type 2 Diabetes: Findings from a Prospective Study with Ro... by Ying-Chuen Lai, Hung-Yuan Li, Ta-Jen Wu, Chi-Yuan Jeng, Lee-Ming Chuang

“…Silencing of acid-labile subunit (ALS) improved glucose metabolism in animal models. The aim of this study is to evaluate the effects of rosiglitazone (RSG) on ALS levels in individuals with type 2 diabetes. …”
Get full text

Notes from Field Work on the Ijemo in Abeokuta by Damilola Osunlakin, Toyin Falola

“…For various reasons related to political contestation and reproduction of historical traditions, these entities preserved their animated past from the historical abyss. Notes adumbrated in this study consist of accounts that take the history of Abeokuta beyond the Sodeke era in the third decade 210 Osunlakin and Falola of the nineteenth century. …”
Get full text

Human Keratinocyte Growth and Differentiation on Acellular Porcine Dermal Matrix in relation to Wound Healing Potential by Robert Zajicek, Vaclav Mandys, Ondrej Mestak, Jan Sevcik, Radana Königova, Eva Matouskova

“…A number of implantable biomaterials derived from animal tissues are now used in modern surgery. Xe-Derma is a dry, sterile, acellular porcine dermis. …”
Get full text

Oxygen-binding proteins aid oxygen diffusion to enhance fitness of a yeast model of multicellularity. by Whitney Wong, Pablo Bravo, Peter J Yunker, William C Ratcliff, Anthony J Burnetti

“…One such mechanism is the presence of oxygen-binding proteins, such as globins and hemerythrins, which arose in the ancestor of bilaterian animals. Despite their importance, the precise mechanisms by which oxygen-binding proteins influenced the early stages of multicellular evolution under varying environmental oxygen levels are not yet clear. …”
Get full text