Potential Effect of Exosomes Derived from Cancer Stem Cells and MSCs on Progression of DEN-Induced HCC in Rats by Faisal A. Alzahrani, Mohammed A. El-Magd, Ahmed Abdelfattah-Hassan, Ayman A. Saleh, Islam M. Saadeldin, Eman S. El-Shetry, Abdelnaser A. Badawy, Saleh Alkarim

Get full text

Establishing an Electrophysiological Recording Platform for Epidural Spinal Cord Stimulation in Neuropathic Pain Rats by Yang CT, Shyu BC, Lin WT, Lu KH, Lin CR, Wen YR, Chen CC

“…To elucidate the mechanism of action among conventional and current novel types of SCSs, a stable and reliable electrophysiology model in the consensus animals to mimic human SCS treatment is essential. …”
Get full text

Perspektywiczne kierunki rozwoju biologii człowieka w Polsce, ze szczególnym uwzględnieniem auksologii by Napoleon Wolański, Anna Siniarska

“…Protoculture has already existed in animals and is manifested by using a natural object as a tool or by coping the habits of another animals being successful in doing something. …”
Get full text

Isoacid supplementation influences feed sorting, chewing behaviors, and enteric methane emissions differentially in mid-lactation dairy cows depending on dietary forage level by M.R.A. Redoy, S. Ahmed, M. Bulnes, D.H. Kleinschmit, M.E. Uddin

Get full text

Assessment of ecological asset quality and its drivers in Agro-pastoral Ecotone of China by Wenmin Liu, Zhiyuan Cheng, Jie Li, Guang Li, Ninghui Pan

“…The distribution pattern of the ecological assets was also obvious, showing a distribution pattern of high in the northeast and low in the middle. (2) The effects of altitude and latitude/longitude on the quality of ecological assets in the study area were mainly characterized by a decreasing trend in the quality of ecological assets with decreasing altitude from west to east, and a decreasing and then increasing trend in the quality of ecological assets with increasing altitude from south to north. (3) The quality of ecological assets has a complex correlation with climate and socio-economic factors, among which, temperature and precipitation are significantly positively correlated in the middle altitude (785–2968 m) and low altitude northwest; socio-economic factors are significantly positively correlated with large and medium-sized agricultural tractors, agricultural, forestry, animal husbandry and fishery population and rural population in the high altitude area, significantly positively correlated with GDP of the primary industry in the middle altitude area, and significantly positively correlated with agricultural population and animal husbandry and fishery population in the low altitude area. (4) The construction of a comprehensive assessment system that introduces soil and terrain indices mainly shows an increase in the proportion of medium and low grades of ecological asset quality and a decrease in the proportion of excellent, good, and poor grades, compared with the quality of ecological assets using only the perpendicular index as the assessment system. …”
Get full text

Serum Pharmacochemistry and Network Pharmacology Reveal Active Compounds and Mechanisms of the Huaxian Formula in Alleviating Radiation-Induced Pulmonary Fibrosis by Gong C, Chen J, Zou P, Fang Z, Quan L, Wang J, Yin J, Lin B, Lang J, Chen M

“…Molecular docking indicated that key compounds in HXF serum, 5,7,8-trimethoxyflavone, and hyperoside, exhibited strong affinity with key targets. Finally, animal experiments confirmed that HXF significantly inhibited the expression of p-Akt and p-PI3K proteins in the lung tissue of irradiated mice.Conclusion: Our research results indicate that HXF may exert its effects on the prevention and treatment of radiation-induced pulmonary fibrosis (RIPF) through multiple pathways and targets, with the PI3K-Akt signaling pathway likely playing the most crucial role in this process. …”
Get full text

From α-to β-diversity: Understanding the historical, present, and future diversity patterns of Fagaceae in Southwestern China by Bikram Pandey, Fengying Zhang, Basu Dev Poudel, Rong Li, Mohammed A. Dakhil, Bishal Gurung, Zhaxi Luobu, Yawen Gan, Ziyan Liao, Lin Zhang

Get full text

Development of an Efficient and Generalized MTSCAM Model to Predict Liquid Chromatography Retention Times of Organic Compounds by Mengdie Fan, Chenhui Sang, Hua Li, Yue Wei, Bin Zhang, Yang Xing, Jing Zhang, Jie Yin, Wei An, Bing Shao

Get full text

Un ensemble funéraire de l’Antiquité tardive à dépôt atypique d’âne à Woippy (Moselle) by Gaël Brkojewitsch, Olivier Putelat

“…The animal was in its prime, and thus represents a significant contribution dedicated to this person who clearly possessed a particular status within the group. …”
Get full text

Le lymphosarcome fausse les résultats du test de la tuberculose effectué sur le sang by Cheick Coulibaly, Julia Seidl, Bettina Bernhard, Roland Plesker

“…La décision fut prise de répéter le test sur cet animal et sur tous ceux qui avaient été en contact avec lui. …”
Get full text

Traitement d’un lymphome agressif chez un babouin naturellement infecté par STLV-1 by Jocelyn Turpin, Sandrine Alais, Ambroise Marçais, Julie Bruneau, Anat Melamed, Nicolas Gadot, Olivier Hermine, Charles Bangham, Romain Lacoste, Renaud Mahieux

“…Comme chez les patients souffrant d’ATLL, l’animal a reçu une combinaison d’AZT (Combivir) et d’interféron alpha (viraféron, 50 μg/semaine) pendant quatre mois. …”
Get full text

miR-26a-5p Attenuates Oxidative Stress and Inflammation in Diabetic Retinopathy through the USP14/NF-κB Signaling Pathway by Jie Bian, Weizhong Ge, Zhengmei Jiang

“…Müller cells were identified via morphology observation under phase contrast microscope and fluorescence staining for glutamine synthetase. The in vivo animal models for DR were constructed using streptozotocin-induced diabetic C57BL/6 mice. …”
Get full text

Delay of innate immune responses following influenza B virus infection affects the development of a robust antibody response in ferrets by Thomas Rowe, Ashley Fletcher, Melissa Lange, Yasuko Hatta, Gabriela Jasso, David E. Wentworth, Ted M. Ross

“…ABSTRACT Due to its natural influenza susceptibility, clinical signs, transmission, and similar sialic acid residue distribution, the ferret is the primary animal model for human influenza research. Antibodies generated following infection of ferrets with human influenza viruses are used in surveillance to detect antigenic drift and cross-reactivity with vaccine viruses and circulating strains. …”
Get full text

Buffalo genetic improvement program in Vene- zuela by José A. Aranguren-Méndez, Rafael M. Román-Bravo, Ricardo A. Briceño-Rojas, Mauricio G. Briceño-Rojas, Luis A. Pacheco-Díaz

“…The implementation of genetic evaluations in the water buffalo through Best Linear Unbiased Prediction (BLUP) through the animal model has increased over the last two decades across several countries. …”
Get full text

Molecular cloning and expression dynamics of Atrogin-1 in muscle tissue of Russian sturgeon (Acipenser gueldenstaedtii) under high salt stress by Yong-Juan Mo, Yi-Li Gao, Shi-Jjian Xu, Bin Wang, Jingping Wu, Peng Yu, Ming Li, Xiangtao Kang, Zhi-Qiang Han

Get full text

Description of a new Ornithodoros (Pavlovskyella) (Ixodida: Argasidae) tick species from Pakistan by Abid Ali, Mehran Khan, Muhammad Numan, Abdulaziz Alouffi, Mashal M. Almutairi, Ronel Pienaar, Minique H. de Castro, Lidia Chitimia-Dobler, Sebastián Muñoz-Leal, Ben J. Mans, Ala Tabor

“…., which were collected from animal shelters in Khyber Pakhtunkhwa, Pakistan. Providing additional collections from that same locality and a comprehensive analysis involving detailed morphological and mitogenome-based comparisons with closely related species, this study formally designates a novel species for these specimens. …”
Get full text

Protective Effects of Gynostemma pentaphyllum Saponins on Liver Injury in Guinea Pigs of Hyperlipemia Based on Oxidative Stress by Tianyi DAI, Donglian LIU, Xingmin QIN, Chengling GAO, Jiayi LI, Hailing KUANG

“…Methods: A total of 32 guinea pigs were randomly divided into a model group, a low dose GPs group (85 mg/kg), a high dose GPs group (170 mg/kg), and a simvastatin group (1.5 mg/kg), with 8 animals in each group. All animals were fed with high-fat diet for 5 weeks to prepare a hyperlipemia model. …”
Get full text

Foodborne Pathogen Assessment in Raw Milk Cheeses by Nicola Costanzo, Carlotta Ceniti, Adriano Santoro, Maria Teresa Clausi, Francesco Casalinuovo

Get full text

Studies on the fertilization of mouse eggs in vitro by Tevfik TEKELİ, Mehmet GÜLER, Melih AKSOY

“…The aim of this study was to test the recommended techniques of in vitro fertilization in Iriice as an experimental animaL<p> Adult female mice of Swiss albino strain were superovulated by intrapeıitonal injection of PMSG and HCG 48 hours apart. …”
Get full text

Effect of rifampicin on the kidney of albino rats by DE Peters, AO Chike

“… The study was designed to investigate the effect of rifampicin on the kidney biomarkers and histopathology of kidney of albino rats. 42 albino rats were used and rifampicin was administered at 1.10mg/120gBW and 0.55mg/120gBW for intervals of 20, 40 and 60days.Animals were sacrificed 24 hours after the last day of administration and blood samples were collected for the estimation of urea and creatinine levels sodium , potassium, chloride and bicarbonate ion concentrations. …”
Get full text