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8301
Cypermethrin-Induced Toxic Effect on Glycogen Metabolism in Estuarine Clam, Marcia Opima (Gmelin, 1791) of Ratnagiri Coast, Maharashtra
Published 2012-01-01“…Toxic effects of cypermethrin were studied by selecting Marcia opima as an animal model. Cypermethrins effect on the total glycogen content of mantle, gill, foot, hepatopancreas, male gonad and a female gonad of an estuarine clam, Marcia opima was examined. …”
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8302
Exploitation végétale des oasis d’Arabie
Published 2013-12-01“…The study of various archaeological contexts permits to recognise an optimal daily use of this plant that provides animal and human food products, fuel and building materials. …”
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8303
Un établissement rural de La Tène finale à Couesmes, La Tesserie (Indre-et-Loire)
Published 2011-12-01“…In the light of the new data resulting from the study of several assemblies coming from varied structures, it is possible to better define the architectural constructions and identify the ceramic, bronze and iron furnishings and also animal bones and seeds. In addition this study enabled comparison to be made with various similar sites in the north of France.…”
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8304
The Roles of Thyroid and Thyroid Hormone in Pancreas: Physiology and Pathology
Published 2018-01-01“…Afterwards, epidemiological investigations and animal test research found a link between autoimmune diseases, thyroid dysfunction, and pancreas pathology; however, the underlying mechanisms remain unknown. …”
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8305
Effect of fermented bee pollen on metabolic syndrome in high-fat diet-induced mice
Published 2021-05-01“…After YB intervention in mice for 16 weeks, the effect on alleviating MetS was evaluated based on MetS serum parameters, hepatic oxidant status markers and gut microbial populations. The results of animal experiment showed that YB intervention attenuated MetS. …”
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8306
Prediction of Gas Chromatography-Mass Spectrometry Retention Times of Pesticide Residues by Chemometrics Methods
Published 2013-01-01“…A quantitative structure-retention relationships (QSRRs) method is employed to predict the retention time of 300 pesticide residues in animal tissues separated by gas chromatography-mass spectroscopy (GC-MS). …”
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8307
Thirty years from FDA approval of pegylated liposomal doxorubicin (Doxil/Caelyx): an updated analysis and future perspective
Published 2025-01-01“…While PLD has gained a strong foothold in relapsed ovarian cancer and metastatic breast cancer, it has not been extensively tested in primary (neoadjuvant) and adjuvant therapy and has not fulfilled the expectations from the results in animal models efficacy-wise. This discrepancy may be due to the large dose gap between mice and humans and the apparent variability of the EPR effect in human cancer. …”
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8308
The unique activity of the bone morphogenetic protein TGH4 affects the embryonic development of Trichinella spiralis and the establishment of vaccine protection
Published 2025-02-01“…Abstract In recent years, animal outbreaks of trichinellosis have been reported in Mexico, China, Algeria, Croatia and others, which is a challenge to meat safety and public health. …”
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8309
Malaria Vaccine Development: Are Bacterial Flagellin Fusion Proteins the Bridge between Mouse and Humans?
Published 2011-01-01“…Experimental data using animal infection models demonstrated that it is possible to induce protective immunity against different stages of malaria parasites. …”
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8310
Form and Function of Sleep Spindles across the Lifespan
Published 2016-01-01“…Despite a broad general understanding of mechanisms of spindle generation gleaned from animal studies, the mechanisms underlying certain features of spindles in the human brain, such as “global” versus “local” spindles, are largely unknown. …”
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8311
AMPK regulates the maintenance and remodelling of the neuromuscular junction
Published 2025-01-01“…Young mice null for skeletal muscle AMPK displayed a neuromuscular phenotype akin to aged animals. Pharmacological AMPK stimulation facilitated its localization in subsynaptic myonuclei, preceded the induction of several NMJ-related transcripts, and enhanced myotube acetylcholine receptor clustering. …”
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8312
Regulation of noradrenaline synthesis, uptake, and degradation in the left ventricle by fatty acid amide hydrolase (FAAH) inhibitor URB597 in the chronic unpredictable stress model...
Published 2024-01-01“…URB597 treatment may have a beneficial effect on the cardiovascular system in an animal model of depression with heightened sympathoneural activity.…”
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8313
Optimal Control Strategies for the Infectiology of Brucellosis
Published 2020-01-01“…Direct contact between susceptible and infective animals or their contaminated products are the two major routes of the disease transmission. …”
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8314
Thrombin Cleavage of Osteopontin Modulates Its Activities in Human Cells In Vitro and Mouse Experimental Autoimmune Encephalomyelitis In Vivo
Published 2016-01-01“…Osteopontin is a proinflammatory cytokine and plays a pathogenetic role in multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis (EAE), by recruiting autoreactive T cells into the central nervous system. …”
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8315
Fetal and Neonatal Levels of Omega-3: Effects on Neurodevelopment, Nutrition, and Growth
Published 2012-01-01“…Omega-3 polyunsaturated fatty acids (n-3 LCPUFAs) play an important role in brain development and function. Evidence from animal models of dietary n-3 LCPUFAs deficiency suggests that these fatty acids promote early brain development and regulate behavioral and neurochemical aspects related to mood disorders (stress responses, depression, and aggression and growth, memory, and cognitive functions). …”
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8316
The Use of Generic Medications for Glaucoma
Published 2020-01-01“…Generics can be brought to the market quickly and at low cost as manufacturers are not required to repeat animal or clinical research on active ingredients already approved for safety and efficacy. …”
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8317
Current Perspectives on Mycobacterium farcinogenes and Mycobacterium senegalense, the Causal Agents of Bovine Farcy
Published 2014-01-01“…The zoonotic potentials of M. farcinogenes and M. senegalense are unknown; few studies reported the isolation of M. senegalense and M. farcinogenes from human clinical sources but not from environmental sources or from other domestic or wild animals.…”
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8318
Optogenetic Stimulation Enhanced Neuronal Plasticities in Motor Recovery after Ischemic Stroke
Published 2019-01-01“…Optogenetics is a functional and structural connection-based approach that can selectively activate or inhibit specific subtype neurons with a higher precision, and it has been widely applied to build up neuronal plasticities of the nervous system, which shows a great potential in restoring motor functions in stroke animal models. Here, we reviewed neurobiological mechanisms of enhanced brain plasticities underlying motor recovery through the optogenetic stimulation after ischemic stroke. …”
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8319
Challenges and Shortcomings of “Settlement Patterns Analysis” Studies in the Archaeology of Iran: A Critical Evaluation and Some Suggestions
Published 2021-10-01“…Accordingly, it is suggested here that the data collection and analysis could be done by using the combined method that considers the following items: the study of historical texts, full coverage survey of the region, and attention to off-site archaeology especially in Neolithic studies, regarding absolute chronologies before going through the settlement pattern analysis, analysis of animal and plant remains, soil analysis and geophysical methods, statistical analysis, use of models and analysis of economic relations between settlements, and finally, the spatial analysis of settlements based on up-to-date theories and models.…”
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8320
The Effect of Folic Acid as Supportive Therapy of Spiramycine on Weight of Foetus to Toxoplasma gondii – Infected Pregnant Mice (Mus musculus)
Published 2019-12-01“…Experimental groups received the treatments for 5 days, then animals of each groups were sacrified. Foetuses were dissected out for observation. …”
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