Efficacy of Thiamine in the Treatment of Postcardiac Arrest Patients: A Randomized Controlled Study by Suntornwit Pradita-ukrit, Veerapong Vattanavanit

“…Thiamine administration has been shown to improve survival in a postcardiac arrest animal study. We aimed to evaluate the efficacy of thiamine in comatose out-of-hospital cardiac arrest (OHCA) patients following return of spontaneous circulation. …”
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Recurrent neural networks with transient trajectory explain working memory encoding mechanisms by Chenghao Liu, Shuncheng Jia, Hongxing Liu, Xuanle Zhao, Chengyu T. Li, Bo Xu, Tielin Zhang

“…Besides activity patterns resembling animal recordings and retained versatility to variable encoding time, TRNNs show better performance in delayed choice and spatial memory reinforcement learning tasks. …”
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SELECTION FOR CATATONIA: EFFECT ON THE SEXUAL FUNCTION AND ESTROUS CYCLE SYNCHRONIZATION by D. V. Klochkov, T. A. Alekhina

“…A statistically significant synchronization of estrous cycles is observed in GC rats kept in standard cages, five to seven animals per cage. It includes a larger number of matches of individual estrus phases to form a group estrus phase of their 4–5-day long estrous cycle. …”
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Novel cisplatin-magnetoliposome complex shows enhanced antitumor activity via Hyperthermia by M. Carmen Jiménez-López, Ana Carolina Moreno-Maldonado, Natividad Martín-Morales, Francisco O’Valle, M. Ricardo Ibarra, Gerardo F. Goya, Ignacio J. Molina

“…Therefore, our approach of magnetic hyperthermia plus CDDP-ML significantly enhances in vitro cell death and in vivo survival of treated animals.…”
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Designing a Long Acting Erythropoietin by Fusing Three Carboxyl-Terminal Peptides of Human Chorionic Gonadotropin β Subunit to the N-Terminal and C-Terminal Coding Sequence by Fuad Fares, Avri Havron, Eyal Fima

“…The therapeutic efficacy of EPO-CTP analog needs to be established in higher animals and in human clinical trials.…”
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Potential Therapies by Stem Cell-Derived Exosomes in CNS Diseases: Focusing on the Neurogenic Niche by Alejandro Luarte, Luis Federico Bátiz, Ursula Wyneken, Carlos Lafourcade

“…These novel approaches should be examined in cellular and animal models to provide better, more effective, and specific therapeutic tools in the future.…”
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Neuroprotection as a Therapeutic Target for Diabetic Retinopathy by Cristina Hernández, Massimo Dal Monte, Rafael Simó, Giovanni Casini

“…Many substances have been tested in animal studies for their neuroprotective properties and for possible use in humans. …”
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Brain targeting based nanocarriers loaded with resveratrol in Alzheimer's disease: A review by Cyrus Jalili, Amir Kiani, Mohammadreza Gholami, Fariborz Bahrehmand, Sajad Fakhri, Somayeh Kakehbaraei, Seyran Kakebaraei

“…Regarding the urgent need for the development of novel treatments for neurodegenerative diseases, researchers have recently perused the function of natural phytobioactive combinations, such as resveratrol (RES), in vivo and in vitro (animal models of AD). Investigations have shown the neuroprotective action of RES. …”
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The effects of local and systemic inflammatory status on iron metabolism and lipid profile in calves by Uğur Aydoğdu, İbrahim Yurdakul

“…After routine clinical examinations of all the animals were performed, 8 ml of blood was taken for blood analysis and biochemical analyses were performed.…”
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Changes in Cytokines of the Bone Microenvironment during Breast Cancer Metastasis by Donna M. Sosnoski, Venkatesh Krishnan, William J. Kraemer, Courtenay Dunn-Lewis, Andrea M. Mastro

“…In this study, we examined levels of MCP-1, IL-6, KC, MIP-2, VEGF, MIG, and eotaxin in femurs of athymic nude mice inoculated via intracardiac injection with MDA-MB-231GFP human metastatic breast cancer cells, MDA-MB-231BRMS1GFP, a metastasis suppressed variant, or PBS. Animals were euthanized (day 3, 11, 19, 27 after injection) to examine femoral cytokine levels at various stages of cancer cell colonization. …”
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Comparisons between Arabidopsis thaliana and Drosophila melanogaster in relation to Coding and Noncoding Sequence Length and Gene Expression by Rachel Caldwell, Yan-Xia Lin, Ren Zhang

“…The quantile regression analysis found that the coding sequence length and gene expression correlations varied, and similarities emerged for the noncoding sequence length (5′ and 3′ UTRs) between animal and plant species. In conclusion, the information described in this study provides the basis for further exploration into gene regulation with regard to coding and noncoding sequence length.…”
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Secondary motor cortex tracks decision value during the learning of a non-instructed task by Elisabete Augusto, Vladimir Kouskoff, Nicolas Chenouard, Margaux Giraudet, Léa Peltier, Aron de Miranda, Alexy Louis, Lucille Alonso, Frédéric Gambino

“…Summary: Optimal decision-making depends on interconnected frontal brain regions, enabling animals to adapt decisions based on internal states, experiences, and contexts. …”
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Scorpion Venom and the Inflammatory Response by Vera L. Petricevich

“…The clinical signs and symptoms observed in humans and experimental animals are related with an excessive systemic host inflammatory response to stings and stings, respectively. …”
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Inhibitory Effect of Aconitine on Colorectal Cancer Malignancy via Inducing Apoptosis and Suppression of Cell Motion by Xuehui Li, Jianglin Hu, Duan Tong, Taotao Yang, Ming Deng

“…Flow cytometry, western blotting, wound healing, and Transwell assays were implemented for examining the aconitine effect on CRC cell apoptosis, migration, and invasiveness. Animal experiments were performed to further elucidate aconitine’s effect on CRC tumorigenesis. …”
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Causes and solutions for fruit and vegetable waste: a participatory approach with Romanian farmers for sustainable agriculture by Ruxandra Malina Petrescu-Mag, Dacinia Crina Petrescu, Iulia Ajtai, Carmen Andreea Roba, Oana Adriana Gica, Lucian Cuibus, Ancuta Tenter, Valentin Toader, Adina Letitia Negrusa, Nicoleta Bican-Brișan

“…The results of the qualitative research methods, including one to one interviews and a community-based causal analysis (CBCA) process, showed that farmers defined FV waste as discarded produce, excluding items used for compost or animal feed. During the CBCA sessions, three commonly identified indirect causes emerged: consumers’ preference for supermarkets and perfectly shaped FV, the difficulties farmers face in accessing supermarkets, and selling imperfect FV. …”
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Hypertension in Metabolic Syndrome: Vascular Pathophysiology by Yolanda Mendizábal, Silvia Llorens, Eduardo Nava

“…Next we discuss the importance of perivascular adipose tissue and the role of adipokines that possess vasoactive properties. Finally, animal models used in the study of vascular function of metabolic syndrome are reviewed. …”
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The Organotypic Longitudinal Spinal Cord Slice Culture for Stem Cell Study by Joanna Sypecka, Sylwia Koniusz, Maria Kawalec, Anna Sarnowska

“…All the processes occurring during axonal growth, regeneration, synapse formation, and myelination could be visualized while being cultured in vitro for up to 4-5 weeks after the slices had been isolated. Both pups and adult animals can undergo the same, equally efficient procedures when going by the protocol in question. …”
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Emerging Themes in the Ecology and Management of North American Forests by Terry L. Sharik, William Adair, Fred A. Baker, Michael Battaglia, Emily J. Comfort, Anthony W. D'Amato, Craig Delong, R. Justin DeRose, Mark J. Ducey, Mark Harmon, Louise Levy, Jesse A. Logan, Joseph O'Brien, Brian J. Palik, Scott D. Roberts, Paul C. Rogers, Douglas J. Shinneman, Thomas Spies, Sarah L. Taylor, Christopher Woodall, Andrew Youngblood

“…Several “needs” emerged from the discussions regarding approaches to the study of forest ecosystems, including (1) consideration of variable spatial and temporal scales, (2) long-term monitoring, (3) development of universal databases more encompassing of time and space to facilitate meta-analyses, (4) combining field studies and modeling approaches, (5) standardizing methods of measurement and assessment, (6) guarding against oversimplification or overgeneralization from limited site-specific results, (7) greater emphasis on plant-animal interactions, and (8) better alignment of needs and communication of results between researchers and managers.…”
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Effects of Borneol on Pharmacokinetics and Tissue Distribution of Notoginsenoside R1 and Ginsenosides Rg1 and Re in Panax notoginseng in Rabbits by Shixiang Wang, Weijin Zang, Xinfeng Zhao, Weiyi Feng, Ming Zhao, Xi He, Qinshe Liu, Xiaohui Zheng

“…In comparison with rabbits administrated Panax notoginseng extract alone, animals simultaneously taking Panax notoginseng extract and Borneol exhibited significant differences in pharmacokinetic parameters of NGR1, GRg1, and GRe, such as increasing their bioavailability. …”
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Early life gut microbiome and its impact on childhood health and chronic conditions by Harold Nunez, Pamela A. Nieto, Ruben A. Mars, Maryam Ghavami, Cheryl Sew Hoy, Kimberley Sukhum

“…This review summarizes evidence for these claims, highlighting compositional changes of the gut microbiome during this critical period of life as well as factors that affect gut microbiome development. Based on human and animal data, we conclude that the early-life microbiome is a determinant of long-term health, impacting physiological, metabolic, and immune processes. …”
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