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  1. 8241

    Flexibilité vocale sous influences sociales chez les primates non-humains by Hélène Bouchet, Marion Laporte, Agnès Candiotti, Alban Lemasson

    Published 2014-03-01
    “…Animal vocal communication, as human language, is primarily a social act. …”
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  2. 8242

    The use of human tissue surrogates in anatomical modeling for gunshot wounds simulations: an overview about “how to do” experimental terminal ballistics by Lucas Meciano Pereira dos Santos, Marcelo Rodrigues da Cunha, Carlos Henrique Bertoni Reis, Daniela Vieira Buchaim, Daniela Vieira Buchaim, Ana Paula Bernardes da Rosa, Leandro Moreira Tempest, José Augusto Parola da Cruz, Rogério Leone Buchaim, Rogério Leone Buchaim, João Paulo Mardegan Issa, João Paulo Mardegan Issa

    Published 2025-01-01
    “…Human tissue simulating materials are currently used in scientific research mainly because they help to avoid possible ethical issues, unlike what happens with studies involving live animals and/or human cadavers. The use of ballistic gelatin as a human soft tissue surrogate stands out, although other types of materials can be used, including polyurethane and polydimethylsiloxane in the simulation of bones and skin respectively, not to mention some computational models that completely replace the physical use of surrogate models for gunshot wound simulation. …”
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  3. 8243

    Tennis Rehabilitation Training-Assisted Paclitaxel Nanoparticles in Treatment of Lung Tumor by Di Hu, YiMin Yang

    Published 2020-01-01
    “…The TA2 series of experimental rats were selected to establish animal lung tumor models, and they were randomly divided into 5 groups: local injection of saline, porphyrin, and low-, medium-, and high-dose paclitaxel nanoparticles for treatment. …”
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  4. 8244

    Amyotrophic Lateral Sclerosis, a Multisystem Pathology: Insights into the Role of TNFα by Massimo Tortarolo, Daniele Lo Coco, Pietro Veglianese, Antonio Vallarola, Maria Teresa Giordana, Gabriella Marcon, Ettore Beghi, Marco Poloni, Michael J. Strong, Anand M. Iyer, Eleonora Aronica, Caterina Bendotti

    Published 2017-01-01
    “…Changes in TNFα levels are reported in blood, cerebrospinal fluid, and nerve tissues of ALS patients and animal models. However, whether they play a detrimental or protective role on the disease progression is still not clear. …”
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  5. 8245

    Gene function revealed at the moment of stochastic gene silencing by Shreyan Gupta, James J. Cai

    Published 2025-01-01
    “…Analysis of real data demonstrates that scSGS can reveal regulatory relationships up- and downstream of target genes, circumventing the survivorship bias that often affects gene knockout and perturbation studies. scSGS thus offers an efficient approach for gene function prediction, with significant potential to reduce the use of genetically modified animals in gene function research.…”
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  6. 8246

    Global Distribution, Public Health and Clinical Impact of the Protozoan Pathogen Cryptosporidium by Lorenza Putignani, Donato Menichella

    Published 2010-01-01
    “…Cryptosporidium spp. are coccidians, oocysts-forming apicomplexan protozoa, which complete their life cycle both in humans and animals, through zoonotic and anthroponotic transmission, causing cryptosporidiosis. …”
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  7. 8247

    Synaptic Plasticity and Excitation-Inhibition Balance in the Dentate Gyrus: Insights from In Vivo Recordings in Neuroligin-1, Neuroligin-2, and Collybistin Knockouts by Peter Jedlicka, Julia Muellerleile, Stephan W. Schwarzacher

    Published 2018-01-01
    “…In this minireview, we discuss recent studies unraveling molecular mechanisms of excitatory/inhibitory synaptic transmission, long-term synaptic plasticity, and dentate granule cell excitability in the hippocampus of live animals. We focus on the role of three major postsynaptic proteins localized at excitatory (neuroligin-1) and inhibitory synapses (neuroligin-2 and collybistin). …”
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  8. 8248

    Role of Bile Acids in Dysbiosis and Treatment of Nonalcoholic Fatty Liver Disease by Caihua Wang, Chunpeng Zhu, Liming Shao, Jun Ye, Yimin Shen, Yuezhong Ren

    Published 2019-01-01
    “…During the past decade, stimulation of bile acid receptors with their agonists has been extensively explored for the treatment of NAFLD in both animal models and clinical trials. Early evidence has suggested the potential of bile acid receptor agonists in NAFLD management, but their long-term safety and effectiveness need further clarification.…”
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  9. 8249

    Rescue RM/CS-AKI by blocking strategy with one-dose anti-myoglobin RabMAb by Xinyue Wang, Ning Li, Lu Han, Ou Qiao, Xin Chen, Pengtao Wang, Lancao Zhang, Yingjie Hou, Fengjiao Bao, Herui Hao, Sania Saeed, Li Zhang, Zizheng Li, Xiaohong Duan, Shuquan Rao, Zichuan Liu, Yanhua Gong

    Published 2025-01-01
    “…A single dose of anti-Mb RabMAb injection is sufficient for emergency rescue in both homologous and heterologous RM/CS-AKI male animal models. The main goal of blocking the passage of free Mb through the glomerular filtration barrier has been achieved by using the anti-Mb RabMAb, which has a long-term stable therapeutic effect within 14 days and promotes phagocytosis of Mb. …”
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  10. 8250

    Cancer Cell Adhesion and Metastasis: Selectins, Integrins, and the Inhibitory Potential of Heparins by Gerd Bendas, Lubor Borsig

    Published 2012-01-01
    “…Preclinical studies confirm that heparin possesses antimetastatic activities that lead to attenuation of metastasis in various animal models. Heparin contains several biological activities that may affect several steps in metastatic cascade. …”
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  11. 8251

    Tospoviruses (Family Bunyaviridae, Genus Tospovirus) by Scott Adkins, Tom Zitter, Tim Momol

    Published 2005-10-01
    “…At this time, the identification and characterization of several similar viruses, including Impatiens necrotic spot virus (INSV), led to the creation of the plant-infecting Tospovirus genus within the Bunyaviridae family, a large group of predominantly animal-infecting viruses. More than a dozen tospoviruses have since been identified and characterized and previously unknown species of the genus continue to be described on a regular basis. …”
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  12. 8252

    Genetic and Biochemical Alterations in Non-Small Cell Lung Cancer by Jackie L. Johnson, Smitha Pillai, Srikumar P. Chellappan

    Published 2012-01-01
    “…Recent advances in the detection of genetic alterations in patient samples along with physiologically relevant animal models has yielded a new understanding of the molecular etiology of lung cancer. …”
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  13. 8253

    O território de circulação do carro de boi alagoano em feiras, festas e oficinas: perlengas de memória e esquecimento. by Pedro Simonard, Walcler de Lima Mendes Junior

    Published 2019-05-01
    “…Next, we approach the profession of driver, the animal control techniques and the uses of the ox cart for locomotion and transportation of cargo. …”
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  14. 8254

    Estimation des teneurs en nitrates dans les eaux potables par l'utilisation de bandelettes réactives : un exercice d’éducation à l’environnement dans la vallée du Sourou au Burkina... by Francis Rosillon, Boubacar Savadogo, Aminata Kabore, Jean Noël Poda, Hortense Bado-Sama, Dayeri Dianou

    Published 2012-09-01
    “…The contaminations would be of multiple origins : animal and human defecation, latrines, waste water, and the use of dynamite for the digging having also been evoked. …”
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  15. 8255

    Evaluation of antioxidant and anti-hypercholesterolemic potential of Vitis vinifera leaves by Sushma Devi, Randhir Singh

    Published 2017-09-01
    “…The anti-hypercholesterolemic activity was evaluated by inducing hypercholesterolemia with high cholesterol diet for 21 days in experimental animals. During the experimental periods parameters like lipid profile, liver function test, atherogenic index and histopathological studies were analysed. …”
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  16. 8256

    Enhancement of Neocortical-Medial Temporal EEG Correlations during Non-REM Sleep by Nikolai Axmacher, Christoph Helmstaedter, Christian E. Elger, Juergen Fell

    Published 2008-01-01
    “…Several previous studies in animals and humans suggest that hippocampal-neocortical interactions crucially depend on the state of alertness (i.e., waking state or sleep). …”
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  17. 8257

    Introducing maximum sustainable yield targets in fisheries could enhance global food security by Christian Elleby, Ignacio Pérez Domínguez, Rasmus Nielsen, Max Nielsen, Ayoe Hoff

    Published 2025-01-01
    “…Maximum sustainable yield management of overfished stocks could increase yields by 10.6 Megatons, equivalent to 12% of total catches and 6% of aquatic animal production in 2022. This would alleviate the need for aquaculture expansion by an equivalent of 3 years of growth in the aquaculture sector at its current level, and reduce meat and feed demand. …”
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  18. 8258

    Epigenetic Modifications and Potential New Treatment Targets in Diabetic Retinopathy by Lorena Perrone, Carmela Matrone, Lalit P. Singh

    Published 2014-01-01
    “…As with other diabetic complications, diabetic retinopathy (DR) is characterized by the metabolic memory, which has been observed both in DR patients and in DR animal models. Evidences have provided that after a period of poor glucose control insulin or diabetes drug treatment fails to prevent the development and progression of DR even when good glycemic control is reinstituted (glucose normalization), suggesting a metabolic memory phenomenon. …”
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  19. 8259

    Microgravity, Stem Cells, and Cancer: A New Hope for Cancer Treatment by Uğur Topal, Cihan Zamur

    Published 2021-01-01
    “…Although studies have been carried out in a simulated microgravity environment in cell culture lines, there are few animal experiments or true microgravity studies. Cancer remains one of the most significant problems worldwide. …”
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  20. 8260

    Tospoviruses (Family Bunyaviridae, Genus Tospovirus) by Scott Adkins, Tom Zitter, Tim Momol

    Published 2005-10-01
    “…At this time, the identification and characterization of several similar viruses, including Impatiens necrotic spot virus (INSV), led to the creation of the plant-infecting Tospovirus genus within the Bunyaviridae family, a large group of predominantly animal-infecting viruses. More than a dozen tospoviruses have since been identified and characterized and previously unknown species of the genus continue to be described on a regular basis. …”
    Get full text
    Article